scholarly journals Thalassemia Major and Associated Psychosocial Problems: A Narrative Review

Author(s):  
Hazel Şahin Tarım ◽  
Fatma Öz

Thalassemia is an inherited disease that causes the production of damaged hemoglobin chains. Patients are diagnosed with thalassemia major due to major clinical signs and deep anemia. This study aimed to examine the major thalassemia and psychosocial aspect of it, which is such an important issue, to serve as a roadmap for better handling these patients and to contribute to the literature. The method used in this study was narrative review. A literature review was conducted by searching the materials published in databases including Web of Science, PubMed, Scopus, and Google Scholar search engine from 2001 to 2020. Besides WHO website was searched. Thalassemia major damages the heart, liver, lungs and endocrine organs due to anemia and iron accumulation. In addition, the patient may experience mental and social problems due to the congenital nature of the disease and its lifelong duration. The psychosocial problems and treatment burdens of thalassemia patients are very high. There are many studies about the prevalence and physical consequences of thalassemia. However, there are not enough articles and researches describing the psychosocial effects of thalassemia on patients and what can be done about these effects. For this reason, this paper focuses on the process of thalassemia and the psychosocial problems it creates to contribute to the literature and to be a roadmap for better handling these patients.

Author(s):  
Tomohiro Gonjo ◽  
Bjørn Harald Olstad

Researchers have quantified swimming races for several decades to provide objective information on race strategy and characteristics. The purpose of the present review was to summarize knowledge established in the literature and current issues in swimming race analysis. A systematic search of the literature for the current narrative review was conducted in September 2020 using Web of Science, SPORTDiscus (via EBSCO), and PubMed. After examining 321 studies, 22 articles were included in the current review. Most studies divided the race into the start, clean swimming, turn, and/or finish segments; however, the definition of each segment varied, especially for the turn. Ideal definitions for the start and turn-out seemed to differ depending on the stroke styles and swimmers’ level. Many studies have focused on either 100 m or 200 m events with the four strokes (butterfly, backstroke, breaststroke, and freestyle). Contrastingly, there were few or no studies for 50 m, long-distance, individual medley, and relay events. The number of studies examining races for short course, junior and Paralympic swimmers were also very limited. Future studies should focus on those with limited evidence as well as race analysis outside competitions in which detailed kinematic and physiological analyses are possible.


2021 ◽  
Vol 11 (16) ◽  
pp. 7417
Author(s):  
Arkaitz Castañeda-Babarro

The Wingate Anaerobic Test (WAT) has been widely used since its creation in 1974. The WAT involves performing a 30 s “all-out” cycling test. The test is currently applied with some modifications, partly due to the evolution of the material used to perform it. The purpose of this text is to act as a guide for the correct use and application of the test, as well as to highlight the importance of controlling many of the variables that may influence its results. Methods: A literature search was conducted in PUBMED/MEDLINE and Web of Science with different combinations of keywords all related to the WAT to obtain a search of 113 papers. Results and discussion: It was observed that variables such as the duration of the test or the resistance used in the cycle ergometer must be adjusted according to the objective and the population evaluated, while others such as the warm-up or the supplementation of different substances can improve performance on the WAT. Conclusions: In order to apply the WAT correctly, variables such as duration, resistance used or warm-up time and intensity must be adjusted according to the evaluated subjects and the aim of the study. Other variables such as position on the bike or equipment used should also be controlled if we want to guarantee its replicability.


Author(s):  
Ali Jafari ◽  
Ahmadali Enayati ◽  
Fatemeh Jafari ◽  
Farzad Motevalli Haghi ◽  
Nasibeh Hosseini-Vasoukolaei ◽  
...  

Background and purpose: Mosquitoes are responsible for the transmission of many pathogens such as malaria, yellow fever, dengue fever, and so on. The control of mosquitoes using chemical insecticides is not always a sensible approach, so, alternative biological control methods, especially the use of larvivorous fishes, can play a significant role in controlling of mosquito larvae. Materials and Methods: In this narrative review study, papers and dissertations were collected without time and language limits from international electronic databases in Google Scholar, PubMed, ScienceDirect, Web of Science, Ovid, Medline and WHO site, and Iranian scientific databases including: Barakatkns, SID, Civilica, Magiran, and Medlib using appropriate keywords from 1937 to 2018. Finally, 55 sources were selected and criticized, interpreted, and analyzed. Results: In the study, some of larvivorous fishes including Aphanius dispar, Carassius auratus (goldfish), Gambusia affinis, and Poecilia reticulate (guppy) have been investigated as important predators of mosquito larvae. Among these fish, Gambusia, Aphanius dispar, Colisa Lalia, Danio rerio, Goldfish, Guppy and Oreochromis mossambica are present in different regions of Iran. Conclusion: Given the fact that malaria carriers are present in many regions of Iran and the climate of Iran is also potentially suitable for the transmission of malaria, it is recommended to use larvivorous fishes that are compatible with the environmental conditions of each area.


Antibiotics ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 93
Author(s):  
Angel-Orión Salgado-Peralvo ◽  
Juan-Francisco Peña-Cardelles ◽  
Naresh Kewalramani ◽  
Alvaro Garcia-Sanchez ◽  
María-Victoria Mateos-Moreno ◽  
...  

As the population ages, more and more patients with orthopaedic prostheses (OPs) require dental implant treatment. Surveys of dentists and orthopaedic surgeons show that prophylactic antibiotics (PAs) are routinely prescribed with a very high frequency in patients with OPs who are about to undergo dental procedures. The present study aims to determine the need to prescribe prophylactic antibiotic therapy in patients with OPs treated with dental implants to promote their responsible use and reduce the risk of antimicrobial resistance. An electronic search of the MEDLINE database (via PubMed), Web of Science, LILACS, Google Scholar, and OpenGrey was carried out. The criteria used were those described by the PRISMA® Statement. No study investigated the need to prescribe PAs in patients with OPs, so four studies were included on the risk of infections of OPs after dental treatments with varying degrees of invasiveness. There is no evidence to suggest a relationship between dental implant surgeries and an increased risk of OP infection; therefore, PAs in these patients are not justified. However, the recommended doses of PAs in dental implant procedures in healthy patients are the same as those recommended to avoid infections of OPs.


2021 ◽  
Vol 33 (3) ◽  
pp. 419-423
Author(s):  
Flavia Noronha ◽  
Sanju Pant ◽  
Renjulal Yesodharan ◽  
Asha Nayak ◽  
Rochelle Dsa

The world is facing an unprecedented challenge of the 21st century in the form of COVID-19 outbreak. People across the culture, race, ethnicity, socio-economic background are being affected by the rippling effects of this pandemic. The aim of this narrative review is to briefly describe the impact of the pandemic on mental health, the vicious cycle of social issues and psychological health caused and aggravated by the Covid-19 pandemic. We also aim to highlight certain interventions to overcome the mental health challenges posed by the pandemic. For this purpose, a thorough search of all databases was done to gather articles relevant to the objective of this narrative review. Keywords were used in combination and separately to identify the articles on the various psychosocial issues caused by the pandemic. Published articles in various databases like Scopus, Web of Science, Pubmed etc., related to psychosocial effects due to COVID-19 were searched and summarized to justify and support the objective of this paper. The coming months will reveal the extent of damage this pandemic has caused to the socio-economic and health sectors across the globe. It is crucial to recognize the psychosocial impact of this pandemic and necessitate the measures to overcome them by mobilizing the resources we have at hand.


2021 ◽  
Vol 15 (2) ◽  
pp. 7-21
Author(s):  
Daniel Rojas-Valverde ◽  
Luis D Rojas-Valverde ◽  
Andrea Fallas-Campos ◽  
Braulio Sánchez-Urena ◽  
Randall Gutiérrez-Vargas

El uso de la ecografía terapéutica (TUS) en la ciencia del deporte, la medicina y la rehabilitación ha aumentado significativamente en la última década. Este crecimiento ha estado acompañado de un gran interés científico por el estudio de las respuestas durante el tratamiento de lesiones y el hallazgo de la dosis óptima. Por lo tanto, el propósito de esta revisión narrativa fue explorar el conocimiento informado hasta la fecha sobre el uso de TUS y las consideraciones metodológicas al aplicarlo en la evaluación de lesiones deportivas. Se realizó una búsqueda electrónica (PubMed [MEDLINE], Science Direct [EMBASE], Web of Science [WoS] y Google Scholar) siguiendo las pautas de revisión sistemática (PRISMA), e incluyó solo revisiones sistemáticas sobre la aplicación de TUS en los deportes. El resultado de esta revisión es la presentación de algunas consideraciones metodológicas al utilizar la TUS en la práctica deportiva, dando una orientación general para su uso de seguridad, eficiencia y efectividad considerando la necesidad de recuperarse rápidamente de las lesiones en el deporte.


2021 ◽  
Vol 11 (3) ◽  
pp. 34101-34101
Author(s):  
Haleh Talaie ◽  
◽  
Sayed Masoud Hosseini ◽  
Maryam Nazari ◽  
Farzad Nazemi ◽  
...  

Background: Fear, anxiety, and stress are natural reactions of the human body to unpredictable and potentially threatening conditions. Currently, individuals are encountering Coronavirus Disease 2019 (COVID-19) pandemic; it is caused by a virulent, partially unknown pathogen with high transmissibility, recognized as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is conceivable to experience anxiety, stress, and subsequent mental health disorders during the pandemic. This narrative review provided a brief overview of mechanisms involved in COVID-19 and mental health disorders as well as the bidirectional association between them. Methods: Scientific electronic databases, such as PubMed, Scopus, Web of Science, and Google Scholar were thoroughly searched, based on different keywords in this study. Results: Lifestyle changes and isolation for breaking the chain of infection facilitate mental health disorders development more than before. Since the onset of the pandemic, the prevalence of mental health disorders has significantly increased. Moreover, studies suggested that the incidence of COVID-19 and the progression of the disease to a severe and life-threatening stage is higher in individuals with a history of mental health disorders. Inflammation is caused by, also may cause mental health disorders. Besides, COVID-19 is associated with cytokine storm and subsequent inflammation. Conclusion: There seems to be a bidirectional association between COVID-19 and mental health disorders, in which inflammation acts as an adaptor.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Maryam Masoumi ◽  
Forouzan Elyasi

Context: Tokophobia is an intense fear of childbirth that may result in considerable outcomes. This phenomenon may also be observed in fathers. However, studies are infrequent on tokophobia frequency and its related factors in fathers. Therefore, this study aimed to address tokophobia in fathers. Evidence Acquisition: A comprehensive literature search was performed in databanks such as Ovid and Google Scholar, as well as electronic databases including PubMed, ProQuest, Web of Science, Science Direct, Magiran, Scientific Information Database (SID), and Barakat (IranMedex), without time limit. Articles were published between 1988 and 2020. Results: Initially, 150 studies were recruited, and finally, 55 of them remained for the final appraisal after omitting unrelated studies. The findings from related studies were organized as the epidemiology of tokophobia in men, biopsychosocial etiology, clinical signs, diagnosis, treatment, and prognosis of tokophobia in men. Considering the tendency of fathers to hide tokophobia, providing suitable knowledge and support from health providers can probably retain the trust in this population and help them cope with tokophobia. Conclusions: During pregnancy, fathers may suffer from fear of childbirth that can impact their health and abilities. Thus, during counseling and prenatal care, the providers should pay attention to fathers.


2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
King Hans Kurnia ◽  
Elvioza Elvioza ◽  
Mohamad Sidik ◽  
Teny Tjitra Sari ◽  
Rita Sita Sitorus

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S730-S730
Author(s):  
Michael Kessler ◽  
Sandip Biswas ◽  
Tsokyi Choera ◽  
Derrick Chen ◽  
Alexander Lepak ◽  
...  

Abstract Background Anterior nares (AN) MRSA PCR can help identify MRSA colonization as a risk factor for MRSA pneumonia and can be especially useful, given high NPV, in making treatment decisions when lower respiratory tract (LRT) cultures are lacking. Oropharynx (OP) MRSA carriage without AN colonization can occur suggesting the potential benefit of duel site screening, but doubles resource utilization. We evaluated concordance between the AN and OP sites and whether the addition of OP MRSA PCR testing provides clinical benefit. Methods MRSA PCR was performed using Xpert SA Nasal Complete (Cepheid; FDA-cleared and modified). Results were retrieved from January 2017 to July 2018 for adult in-patients who received both AN and OP testing within the same calendar day. Medical charts were reviewed for a clinical course, respiratory culture results, and effect of discordant PCR results. Results AN and OP MRSA PCRs were performed on 1,419 adult inpatients, concordance was 96.5% (n = 1370, see Table). In 38 of 49 discordant cases, PCR was used to evaluate the etiology of pneumonia. Of those, 22 (58%) had LRT culture results available within 48 h to direct therapy. We further evaluated the value of OP PCR by focusing on AN-/OP+ (n = 22) discordant results, of which 16 were used to evaluate pneumonia. LRT culture results were available in 7 (44%) of these cases. Three had isolation of MRSA; however, the remaining 4 were culture-negative but still received vancomycin for an average of 5 days. Of the 9 that were AN−, OP+, and without culture results, only 4 had clinical signs and symptoms consistent with MRSA pneumonia. OP MRSA PCR is $303. Conclusion OP and AN MRSA PCR screening are highly concordant in patients with pneumonia. 355 AN/OP PCRs (4/1419), at > $100,000 in additional healthcare costs, were needed to detect one potentially missed MRSA pneumonia compared with AN PCR only approach. Our results suggest addition of OP MRSA PCR: (1) has limited clinical utility for pneumonia evaluation as it is unlikely to be discordant with AN testing, which will not significantly alter the very high NPV and when discordant (AN-/OP+) has a <50% PPV, (2) is unlikely to be cost-effective, and (3) has unintended consequences such as overuse of MRSA therapy. Additionally, there is an opportunity to improve PCR ordering to include only those situations in which LRT cultures are lacking. Disclosures Alexander Lepak, MD, Paratek Pharmaceuticals: Research Grant; Tetraphase Pharmaceuticals: Research Grant.


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