The Role of Clinical Guidelines for the Management of Chemotherapy-Induced Nausea and Vomiting in Children with Cancer

Author(s):  
Hamid Farhangi ◽  
Ali Ghasemi ◽  
Mojgan Bahari ◽  
Zohreh Alirezaei ◽  
Akram Rabbani Javadi ◽  
...  

Background: Nausea and vomiting are among the most important side-effects associated with chemotherapy in children with cancer, affecting the quality of their lives. Clinical guidelines for selecting antiemetics are effective in reducing acute chemotherapy-induced nausea and vomiting (CINV). Materials and Methods: The present quasi-experimental study compared the effectiveness of the Pediatric Oncology Group of Ontario (POGO) CINV guideline with that of conventional arbitrary therapies for CINV in 82 children aged 6 months to 16 years old. Out of 177 cycles of chemotherapy, in 101 cycles patients were treated according to POGO-CINV Guideline; in the other 76 cycles, patients were treated with arbitrary types and doses of antiemetics. Then, vomiting in the first 24 hours after chemotherapy in both groups was measured and compared. Results: In this study, 82 patients hospitalized in the Hematology Department of Dr. Sheikh Children’s Hospital were enrolled, of whom 48 patients (58.7%) were boys and 34 (41.3%) were girls. The mean age of patients was 6.24±4.47 years (6 months to 16 years). The results of the current study showed that using a protocol for the prevention of vomiting based on the patient’s age and the type of chemotherapy is superior to conventional management of CINV. Findings showed that the frequency of nausea and vomiting in the protocol group was significantly reduced in comparison with the control group (p˂0.005). Moreover, a reduction in the frequency of nausea and vomiting was quite significant in the sub-categories of the protocol group who had received high-risk or moderate-risk emetogenic drugs (p˂0.005). Conclusion: The results of the current study showed that using the POGO guideline, which takes into account the patient’s age and the type of chemotherapy, is more effective than arbitrary management of CINV, particularly in children.

2021 ◽  
Vol 15 (5) ◽  
pp. 1774-1779
Author(s):  
Sanaz Nehbandani ◽  
Hajar Salehi ◽  
Khadije Rezaie Keikhaie ◽  
Hossein Rashki Ghalenow ◽  
Fatemeh Mirzaie ◽  
...  

Introduction & Objective: Nausea and vomiting during pregnancy is one of the most common gastrointestinal disorders that more than 85% of pregnant women experience. However, controlling and treating this complication is still one of the most important issues in antenatal care. Therefore, the aim of this study was to investigate the effect of ear acupressure at Shen Men point on relieving nausea, vomiting and retching during pregnancy. Materials and Methods: In this quasi-experimental study, 100 pregnant women with a gestational age of less than 16 weeks attending the health clinics of Zabol city during 2019-2020 were studied in two control and intervention groups (n = 50 in each group). The samples in the intervention group were trained to apply pressure on their ears’ Shen Men point with the thumb for three minutes three times a day (morning, noon, and night), for a duration of one month. At the end of second and fourth weeks, the data were collected using the Rhodes index form and then, were analyzed by SPSS software version 22. Results: According to the results, there was no significant difference between the two groups in terms of age, gestational age, occupation and education. The difference in the mean scores of nausea, vomiting and retching was not statistically significant between the control and intervention groups before the study. But four weeks after the study, a significant difference was observed in the mean scores of vomiting, nausea and retching between the two groups, so that the mean scores of vomiting, nausea and retching were significantly lower in the intervention group than in the control group. Conclusion: The ear acupressure medicine at the Shen men point can be used as a non-invasive, safe and inexpensive method to relieve nausea, vomiting and retching during pregnancy. Keywords: Acupressure medicine, Shen Men, Vomiting, Pregnancy, Nausea, Retching, Rhodosis


2016 ◽  
Vol 19 (2) ◽  
pp. 145-152 ◽  
Author(s):  
Chi-Hsiang Shen ◽  
Li-Yu Yang

Nausea and vomiting are the most common side effects of antineoplastic chemotherapy. However, only a small number of studies have been conducted in Taiwan to determine the efficacy of acupressure in treating these side effects in cancer patients receiving chemotherapy. In this quasi-experimental study, we aimed to explore the effects of acupressure on meridian energy as well as nausea and vomiting in 70 lung cancer patients receiving chemotherapy. Patients were assigned to the experimental or control group based on order of hospital admission. The experimental group received acupressure on “Neiguan (PC6)” and “Gongsun (SP4)” points, and the control group received sham acupoint patches on “Houxi (SI3)” point. The results showed that the mean meridian energy in the experimental group after acupressure was significantly higher than in the control group ( F = 28.71, p < .001). The experimental group had significantly less nausea ( p < .001) and vomiting ( p = .006) during the delayed phase than the control group. In conclusion, acupressure significantly increased the mean meridian energy and effectively decreased the severity of nausea and vomiting in lung cancer patients undergoing chemotherapy. We recommend that clinical nurses provide acupressure as an intervention to relieve nausea and vomiting in patients receiving chemotherapy.


2021 ◽  
Author(s):  
Azam Amzajerdi ◽  
Maryam Keshavarz ◽  
Ali Montazeri ◽  
Reza Bekhradi

Abstract Objective: The present study was performed to determine whether lavender oil affects nausea-vomiting and anxiety in pregnant women.Methodology: In a quasi-experimental study, sixty-six pregnant women in the 6th to 16th week of pregnancy with a range of mild to moderate nausea and vomiting were randomized into two groups; a Lavender and a control group (n = 33 for each group). Twice a day (before rest in the afternoon and night sleep) for a week, samples in the intervention and control group inhaled Lavender and sesame oil, respectively. Every night before sleeping, the Rhodes nausea-vomiting questionnaire was completed by the subjects. In addition, Maternal State Anxiety (MSA) in mothers of two groups was measured by using the state anxiety scale before and on the seventh day of the intervention. Results: Seven days after inhalation of Lavender oil, the overall mean score of Rhodes index and the severity of nausea and vomiting (p = 0.008, p = 0.032, respectively), also the mean scores and severity of MSA in mothers of the Lavender group were significantly lower than the control group (p = 0.012 and p = 0.027, respectively). According to the repeated measures analysis, the mean score of the Rhodes index was significantly decreased in the Lavender and control groups during one week (p = 0.0001 and 0.004, respectively).Conclusion: This study presented evidence that Lavender aromatherapy could decrease nausea, vomiting, and anxiety in pregnant women. The findings can guide healthcare workers in providing aromatherapy to women throughout pregnancy.


2021 ◽  
Vol 15 (6) ◽  
pp. 1602-1606
Author(s):  
Sanaz Nehbandani ◽  
Hajar Salehi ◽  
Khadijerezaie Keikhaie ◽  
Hossein Rashki Ghalenow ◽  
Fatemeh Mirzaie ◽  
...  

Background: Nausea and vomiting during pregnancy is one of the most common gastrointestinal disorders that more than 85% of pregnant women experience. However, controlling and treating this complication is still one of the most important issues in antenatal care. Aim: To investigate the effect of ear acupressure at Shen Men point on relieving nausea, vomiting and retchingduring pregnancy. Methods: In this quasi-experimental study, 100 pregnant women with a gestational age of less than 16 weeks attending the health clinics ofZabol city during 2019-2020 were studied in two control and intervention groups (n = 50 in each group). The samples in the intervention group weretrained to apply pressure ontheirears’Shen Men point with the thumb for three minutes three times a day (morning, noon, and night), for a duration of one month. At the end of second and fourth weeks, the data were collected using the Rhodes index form and then, were analyzed by SPSS software version 22. Results: According to the results, there was no significant difference between the two groups in terms of age, gestational age, occupation and education. The difference in the mean scores of nausea, vomiting and retching was not statistically significant between the control and intervention groups before the study. But four weeks after the study, a significant difference was observed in the mean scores of vomiting, nausea and retching between the two groups, so that the mean scores of vomiting, nausea and retching were significantly lower in the intervention group than in the control group. Conclusion: The ear acupressure medicine at the Shen men point can be used as a non-invasive, safe and inexpensive method to relieve nausea, vomiting and retching during pregnancy. Keywords :Acupressure medicine, Shen Men, Vomiting, Pregnancy, Nausea, Retching, Rhodosis


2018 ◽  
Vol 3 (2) ◽  
pp. 127 ◽  
Author(s):  
Hend Abdallah EL Sayed ◽  
Samia Abdel Hakeem Hanseen Aboud

Aim of the study was to investigate the effect of an educational intervention on quality of life and sexual function in women with endometriosis. Design: Quasi experimental time series research design. Setting: obstetrics and gynecology outpatient clinic affiliated to Benha University Hospital and Benha teaching Hospital. Sample: A purposive sample of 138 women diagnosed with endometriosis was eligible in the study and assigned equally into study and control groups. Tools for data collection: A structured interviewing questionnaire, Endometriosis Health Profile Questionnaire-30 and Sexual Health Outcomes in Women Questionnaire. Results: There was no statistically significant difference between both groups regarding demographic and obstetrical characteristics (p ˃ 0.05). Before implementation of educational intervention, the mean scores of total EHP-30 and SHOW-Q showed impaired quality of life and sexual function in the both groups (p ˃ 0.05). After one and two months of educational intervention implementation, mean total score of EHP-30 was significantly lowered in the study group compared with the control group. The mean scores of satisfaction, orgasm, and desire subscales were significantly higher in study group compared with control group. Whereas, the mean score of the pelvic problem interference subscale was significantly lower in study group compared with control group (p ≤ 0.001). Conclusion: The educational intervention about endometriosis has significant effect on the improvement of women's quality of life and sexual function. Recommendation: Provide health educational program for women with endometriosis to improve quality of life as well as sexual function.


Author(s):  
Fielda Djuita ◽  
Harsono Mardiwiyoto ◽  
Ova Emilia ◽  
Soehartati Soehartati

Background: Clinical Audit is one of the formative evaluations that conducted to maintain and increase behavior and performance of the Radiation Oncology students, as an effort to maintain radiotherapy services and grant the quality of education. The objective of this study is to evaluate the role of clinical audit in improving students’ behavior.Method: This was a quasi-experimental research time series. We have done audit to the medical record chart of the residences at Policlinic I, II, III and stay at semester 3, 4, 5 in FK UI/RSUPNCM between September 2010 and December 2011 (T0). Audit had done by the author and one of the lectures. After analyzing the audit report, the reports were sent to the students one by one through email followed by forwarding it to the lecturer involved in this research. Then we continue the audit by performing the second clinical audit (T1) from January until March 2011. We used the mean score from the two auditors. The score divided into 4 groups as follows: hospital clinical record, treatment prescription, simulation and planning also evaluation during treatment. After that the author compared the audit score before and after intervention with t-test.Results: There were 16 Oncology Radiation students with 163 cases (To) and 156 cases (T1) who worked at Policlinic I, II and III. Behavior mean score is 1.9229 (T0), standard deviation 0.0514 and mean score after first intervention is 1.9764, standard deviation 0.0479 with p= 0.006.Conclusion: The students’ behaviors and performance are changed significantly after intervention.


2021 ◽  
Vol 8 (8) ◽  
Author(s):  
Styliani Gidari ◽  
Domna - Mika Kakana

<p>Research findings suggest that teachers’ education and training is a key factor in improving the preschool quality. Teachers’ qualifications can lead to high-quality preschool education and positive developmental outcomes for the children. This study examines the effectiveness of the teachers’ professional development program “Upgrading the Quality of the Preschool Environment” on improving the quality of the Kindergartens. The research followed a quasi-experimental design and included 26 kindergarten teachers from 23 public Greek kindergartens, who were divided into an Experimental and a Control Group. The quality of the kindergartens was initially assessed using the ECERS-R scale and a five-month professional development program, based on this initial evaluation and on collaborative practices, was designed and implemented to the Experimental Group. Our results show that although the mean scores of quality before the implementation of the program did not differ significantly (t = 6.45, p =.52), the mean scores, for the Experimental Group (M = 4.71, SD = .62) were significantly higher after the intervention (t = 4.30, p &lt;001) than those of the Control Group (M = 3.78, SD = .37). The follow up evaluation one and a half years later showed the maintenance and further improvement of the results of the program in the quality of the kindergartens. Our research provides useful information that can be used in the future for the designing of professional development programs aimed at improving the quality of the preschool environment.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0756/a.php" alt="Hit counter" /></p>


2019 ◽  
Author(s):  
Nur Tsalits Fahman Mughni

Teaching materials by integrating local culture makes easier for students to understand the subject matter in the learning process. The aims of the study is to measure the effectiveness of teaching materials based on local wisdom of agriculture in Binjai in improving the students problem solving abilities. The research method was a quasi experimental which use non equivalent control group in the pretest posttest design. The sample of study were students of Senior High School grade X in Binjai that consisted of experiment group which used teaching materials based on local wisdom of agriculture in Binjai and control group that used student handbooks. Teaching materials are tested by material experts and technology experts to ensure the quality of teaching materials. Data collection was conducted through test. The results showed that the teaching materials based on local wisdom of agriculture in Binjai effective in improving students problem solving abilities in the experimental group students based on the results of N gain value was 0.67 which has medium criteria. It means teaching materials based on agricultural local wisdom of agriculture in Binjai can be used as one of the teaching materials in learning activities.


Author(s):  
Muhammad Irfan ◽  
Safdar Abbas ◽  
Beenish Jehan Azhar ◽  
Shakeel Ahmad ◽  
Hafsa Muhammad ◽  
...  

Background: Phytonutrients in peach fruits have health promoting antioxidants against various chronic diseases. However, there is no extensive data to show the nutritional values of Local peach cultivars after post-harvest treatments. Objective: Mainly this study was objective to determine the effect of calcium carbide on nutritional value and quality of fruits of Pakistani peach cultivars. Methods: The peach fruits were collected from three different peach orchids of KPK and the fruits were divided into 4 groups while 5th group was collected from local fruit shop. Each experimental group was treated with different concentration of calcium carbide whereas control group was not treated. The peel and pulp samples were oven dried and ground to fine powder separately. The elemental compositions were determined using Particle Induced X-ray emission and Pelletron Tandem Accelerator. Result: Sixteen elements were identified in peach fruits and the elements were Al, P, S, Cl, K, Ca, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, and Se. In peel, concentration of some elements increased or decreased after treatment with CaC2 while in pulp the conc. of nearly all detected elements was increased in treated samples. We found significantly high amount of heavy metals traces including As, Se, Co, Si, and P in peach fruits treated with CaC2. Interestingly, the presence of trichomes in peach skin prevents the transfer of these heavy metals deep into the pulp which was also verified by the elemental profiling of nectarines. Conclusion: Conclusively, the artificial ripening with CaC2 changed the nutritional value of peach fruits that has higher health risks if consume with the peel. According to our best knowledge, this is the first report that highlights the effects of CaC2 which deteriorate the nutritional value of peach fruits in Pakistan.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Ya-ping Xu ◽  
Pei-yu Zhao ◽  
Yi-tong Bai ◽  
Shuang Li

Abstract Background The coronavirus disease (COVID-19) pandemic has had a massive impact on individuals globally. The Chinese government has formulated effective response measures, and medical personnel have been actively responding to challenges associated with the epidemic prevention and control strategies. This study aimed to evaluate the effect of the implementation of a care transition pathway on patients that underwent joint replacement during the COVID-19 pandemic. Methods A quasi-experimental study was designed to evaluate the effect of implementing a care transition pathway for patients who underwent joint replacement during the COVID-19 pandemic in the orthopedic department of a tertiary care hospital in Beijing, China. Using a convenient sampling method, a total of 96 patients were selected. Of these, 51 patients who had undergone joint replacement in 2019 and received treatment via the routine nursing path were included in the control group. The remaining 45 patients who underwent joint replacement during the COVID-19 epidemic in 2020 and received therapy via the care transition pathway due to the implementation of epidemic prevention and control measures were included in the observation group. The quality of care transition was assessed by the Care Transition Measure (CTM), and patients were followed up 1 week after discharge. Results The observation group was determined to have better general self-care preparation, written planning materials, doctor-patient communication, health monitoring, and quality of care transition than the control group. Conclusions A care transition pathway was developed to provide patients with care while transitioning through periods of treatment. It improved the patient perceptions of nursing quality. The COVID-19 pandemic is a huge challenge for health professionals, but we have the ability to improve features of workflows to provide the best possible patient care.


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