scholarly journals Comparison of serum level of some trace elements and vitamin D between patients with premenstrual syndrome and normal controls: A cross-sectional study

2019 ◽  
Author(s):  
Mahnoosh Fatemi ◽  
Maryam Allahdadian ◽  
Mehrnoosh Bahadorani
Keyword(s):  
Vitamin D ◽  
Trace Elements ◽  
Serum Level ◽  
Premenstrual Syndrome ◽  
Cross Sectional Study ◽  
Female Students ◽  
Control Group ◽  
Cross Sectional ◽  
Calcium Magnesium ◽  
Normal Controls

Background: Premenstrual syndrome (PMS) is a common problem among women and is identified by reversal emotional, psychological, and physical signs during the luteal phase. These signs, however, lower down in the follicular phase. The cause of PMS isn’t very well-known up to now control group and many researchers have suggested that mineral compounds and vitamins can inhibit these symptoms. Objective: The objective of this study is to compare the serum level of some trace elements and vitamin D between normal controls and patients with PMS. Materials and Methods: 300 female students (19–21 yr old) from Falavarjan County were randomly selected and asked to complete a standard questionnaire on PMS during three menstruation cycles. The students were divided into two groups: healthy persons (control) and PMS persons, and PMS was determined on the basis of the answers to the questionnaire. Thereafter, the serum concentrations of zinc, iron, calcium, magnesium, potassium, sodium, and Vitamin D3 were measured and compared between the two groups. Results: Our results showed that the PMS prevalence was about 41.5%. The level of vitamin D decreased in both the control and PMS groups, with a significantly lower range of vitamin D (p 0.05) in the PMS group. Other factors had no significant change between the two groups. Conclusion: Vitamin D deficiency was probably one of the most important causes of unpleasant symptoms of PMS between these students. Key words: Premenstrual syndrome, Trace elements, Vitamin D.

scholarly journals Serum level of vitamin D and trace elements in children with recurrent wheezing: a cross-sectional study

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Metin Uysalol ◽  
Ezgi Pasli Uysalol ◽  
Yasin Yilmaz ◽  
Gunes Parlakgul ◽  
Tulin Ayse Ozden ◽  
...  
Keyword(s):  
Vitamin D ◽  
Trace Elements ◽  
Serum Level ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Recurrent Wheezing ◽  
Cross Sectional

scholarly journals Homocysteine, trace elements and oxidant/antioxidant status in mild cognitively impaired elderly persons: a cross-sectional study

2015 ◽  
Vol 53 (4) ◽  
pp. 336-342 ◽  
Author(s):  
Hajar Negahdar ◽  
Seyed Reza Hosseini ◽  
Hadi Parsian ◽  
Farzan Kheirkhah ◽  
Abbas Mosapour ◽  
...  
Keyword(s):  
Trace Elements ◽  
Cognitive Impairment ◽  
Antioxidant Status ◽  
Clinical Signs ◽  
Cross Sectional Study ◽  
Control Group ◽  
Elderly Persons ◽  
Effective Parameters ◽  
Cross Sectional ◽  
Significant Difference

Abstract Introduction. Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer’s disease (AD), so identification of the related risk factors can be helpful. There are controversial data regarding the serum oxidant/antioxidant status, trace elements and homocysteine (Hcy) as effective parameters in this disease, therefore the status of these factors was determined in this study. Methods. One hundred-twenty elderly persons with cognitive impairment and 120 elderly healthy persons who were differentiated using Mini-mental state examination (MMSE) participated in this study. The patients were divided into mild and moderate-to-severe cognitive impairment group. Serum antioxidant/oxidant, copper (Cu), manganese (Mn), zinc (Zn) and Hcy concentrations were measured using routine methods. Results. Oxidant and antioxidant levels increased and decreased based on the severity of the disease and were higher and lower in patients than in control group, respectively (p<0.001). With adjusting for age, gender and education, significant difference in Hcy levels was not observed. There was no significant difference in trace elements levels among groups. Conclusions. Results confirmed the association between oxidative damage with increasing the severity of cognitive impairment. These factors may be involved in the etiology of cognitive impairment and AD. Identification of such biomarkers is important to select appropriate treatment goals before the onset of irreversible clinical signs.

scholarly journals Vitamin D Supplementation in Tuberculosis Patients: A Cross Sectional Study

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Dina Keumala Sari ◽  
Nurfida Khairina Arrasyid ◽  
Y. S. Harahap
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Vitamin D Supplementation ◽  
Sectional Study ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

Previous studies have not been able to show with certainty the effect of vitamin D supplementation in tuberculosis patients. The objective of this study is to determine whether vitamin D supplementation to patients with tuberculosis could influence 25-hydroxyvitamin D (25(OH)D) and calcium serum levels. The results, after 28 days, the vitamin D supplementation showed significant increase of 25(OH)D serum level at the end point (p=0.001), but not for the calcium serum level (p=0.3). The Conclusions is supplementation with 1,000 IU vitamin D per day increased the 25(OH)D serum level but there was no association with the calcium serum level.

scholarly journals Premenstrual Syndrome in Students of a Teaching Hospital

2019 ◽  
Vol 17 (2) ◽  
pp. 253-257
Author(s):  
Dhan Bahadur Shrestha ◽  
Shreya Shrestha ◽  
Debika Dangol ◽  
Barun Babu Aryal ◽  
Sabina Shrestha ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Premenstrual Syndrome ◽  
Cross Sectional Study ◽  
Severe Form ◽  
Female Students ◽  
Premenstrual Symptom ◽  
Chi Square ◽  
Cross Sectional ◽  
Patient Profile ◽  
Symptom Screening

Background: Premenstrual syndrome is group of psychosomatic symptoms which occurs during second half of menstrual cycle. Significant number of reproductive aged females suffer from it with its impact on their daily activities. This study was conducted to assess the prevalence, severity and impacts of Premenstrual syndrome on female students of a teaching hospital of Kathmandu, Nepal.Methods: This cross-sectional study was conducted among female students of a teaching hospital from Kathmandu over a period of three months. Premenstrual Symptom Screening Tool was used to quantify the symptoms severity and their effect in activities. In addition; patient profile, socioeconomic status were recorded. The obtained information was entered in Statistical Package for Social Sciences and analyzed. Findings were then interpreted using chi-square test.Results: Out of the 285 respondents, 206 (72.3%) reported at least one premenstrual syndrome symptom of moderate to severe intensity among which 74 (25.9%) had at least one severe symptom. Six individuals (2.1%) fulfilled all criteria for Pre-Menstrual Dysphoric Disorder and 49 (17.2%) fulfilled the criteria for moderate to severe premenstrual syndrome and rest (80.7%) were having no or mild premenstrual syndrome with isolated symptoms. PMS was found to have significant association to menstrual bleeding (p?0.001) and severity of dysmenorrhea (p?0.001), family history of premenstrual syndrome (p=0.019) and physical activity (p=0.021). Conclusions: Premenstrual syndrome is common in female and has a considerable impact on day to day activities activities although its severe form Pre-Menstrual Dysphoric Disorder is less common.Keywords: Female students; Nepal; premenstrual syndrome.

scholarly journals 25(OH)D Inadequacy Has Different Pathway with VEGF in Increases the Risk of Severe Preeclampsia

2015 ◽  
Vol 23 (2) ◽  
pp. 42
Author(s):  
Hanifa Erlin Damayanti ◽  
Aditiawarman Aditiawarman
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Vitamin D Deficiency ◽  
Sandwich Elisa ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Chemiluminescent Immunoassay ◽  
Risk Of Preeclampsia

Objectives: To identify in vivo correlation between 25(OH)D and VEGF in severe preeclampsia.Materials and Methods: A case control, cross sectional study of 36 pregnant women which consist of 18 patients with preeclampsia and 18 patients as control with gestational age-matched. We perform 25(OH)D serum examination by chemiluminescent immunoassay (CLIA) and VEGF serum examination by sandwich ELISA to all patients.Results: All patients are in 25(OH)D insufficiency and deficiency state. Both maternal 25(OH)D and VEGF levels were inversely associated with the risk of preeclampsia (both P<0.05). There is no correlation between 25(OH)D serum level and VEGF serum level (P=0,629).Conclusion: Maternal vitamin D deficiency is associated with increased preeclampsia risk. However, our data do not support the hypothesis that the association between vitamin D deficiency and preeclampsia is mediated by impaired level of VEGF.

Biochemical Changes in Neonates with and without Seizure: A Comparative Study

2021 ◽  
Vol 8 (1) ◽  
pp. 25-29
Author(s):  
ASM Shahidullah ◽  
Rafika Afrose ◽  
Kalpona Deb ◽  
Bina Sen ◽  
Arup Ratan Paul ◽  
...  
Keyword(s):  
Serum Calcium ◽  
Femoral Vein ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Sodium Potassium ◽  
Pediatric Age Group ◽  
Group I ◽  
Calcium Magnesium ◽  
Group Ii

Background: Seizure is a common neurological disorder in the pediatric age group. Objective: Neonates with seizure have decreased in serum calcium, magnesium, sodium, potassium, and glucose if compared to neonates without seizure. Methodology: This comparative cross-sectional study was carried out in the Department of Biochemistry at Mymensingh Medical Collage, Mymensingh, Bangladesh in cooperation with the Department of Pediatric of Mymensingh Medical Collage & Hospital, Mymensingh, Bangladesh from July 2005 to June 2006. Neonates were included in the study. Subjects were divided into two groups designated as group I as control group and group II cases. From each subject at least 2 ml of blood were collected from femoral vein and was collected serum for biochemical analysis. Result: A total of 60 neonates were included in the study. Subjects were divided into two groups-group-I control- (n=20) and group II cases-(n=40). The concentration of serum calcium, magnesium, sodium, potassium, and glucose yielded 7.33 ±0.79, 5.79 ±1.10; 2.18 ± 0.23,1.61 ± 0.25; 134.82 ±3.03, 133.68±8.57; 4.80 ±0.56,5.89 ±2.02; 66.33 ± 8.23, 62.25± 7.96 in group I and group II respectively. Conclusion: Significant decreases of serum calcium, magnesium and significant increase of serum potassium in neonates with seizure are found in this study. The change in serum sodium and glucose are not significant. Journal of Current and Advance Medical Research, January 2021;8(1):25-29

Evaluation of vitamin D levels in patients with primary hypothyroidism: A cross-sectional study

2021 ◽  
Vol 8 (3) ◽  
pp. 193-197
Author(s):  
Minakshi Kumari ◽  
Rajiv Kumar Mahli ◽  
Sunil Kumar Verma ◽  
Vinod Kumar
Keyword(s):  
Vitamin D ◽  
Cross Sectional Study ◽  
Primary Hypothyroidism ◽  
Control Group ◽  
Thyroid Peroxidase ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
Lower Vitamin ◽  
Hypothyroid Patients

Vitamin D deficiency (VDD) and hypothyroidism have been linked in research with inconsistent outcomes. Because of the controversy surrounding these two disorders and their relatively high incidence, we undertook a case-control research comparing the prevalence of VDD in hypothyroid patients (both TPO-Ab positive and negative) to euthyroid controls. This is a cross-sectional study with a single centre. Adults (aged 18 and above) of both sexes with primary hypothyroidism (TSH &#62;5.1 mIU/L) were included (n = 165), as were age and sex matched euthyroid (TSH 5 mIU/ml) controls (n = 165) from the outpatients' department. Biochemical parameters like Thyroid stimulating hormone (TSH), free T4 (fT4), 25 hydroxy vitamin D (Vit D) and thyroid peroxidase antibody (TPO-Ab) were tested in both the groups.The study involved 330 patients, with 165 (mean age 46± 15 years) having primary hypothyroidism (3 having subclinical hypothyroidism) and 165 (mean age 45± 17 years) being euthyroid controls. VDD was seen in 96 percent of hypothyroid patients compared to 90 percent in the control group. The hypothyroid group had a significantly lower mean Vitamin D level than the euthyroid group (12.03± 8.6 SD vs. 17.49± 11.89 SD [ng/ml]; P= 0.001). TPO-Ab was found in two-thirds of the hypothyroid group (110/165). The mean Vitamin D level in the TPO-Ab positive hypothyroid group was 10.4± 7.2 ng/ml, compared to 15.3± 10.3 ng/ml in the TPO-Ab negative group (P = 0.004). With increased TPO-Ab titers, there was a downward trend in Vitamin D levels. A direct association between Vitamin D levels and TPO-Ab, on the other hand, did not reveal any relevance. Patients with hypothyroidism had considerably lower vitamin D levels than euthyroid controls. TPO-Ab positive individuals had lower vitamin D levels than TPO-Ab negative patients.

scholarly journals Verbal behavior in Alzheimer disease patients: Analysis of phrase repetition

2010 ◽  
Vol 4 (3) ◽  
pp. 202-206 ◽  
Author(s):  
Juliana Francisca Cecato ◽  
José Eduardo Martinellil ◽  
Luana Luz Bartholomeu ◽  
Ana Paula Basqueira ◽  
Mônica Sanches Yassuda ◽  
...  
Keyword(s):  
Alzheimer Disease ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Language Problems ◽  
Dsm Iv ◽  
Echoic Behavior ◽  
Repetition Task ◽  
Normal Controls

Abstract Language problems in the elderly with AD are due to the fact that deterioration occurs not only in semantic memory, but in a group of cognitive factors, evidenced by a deficiency in search strategies for linguistic information. Objectives: To evaluate phrase repetition in two cognitive tests, the MMSE and MoCA, in a group of Alzheimer disease patients (AD) and normal controls. Methods: A Cross-sectional study was conducted involving 20 patients who sought medical assistance at a geriatric institute in Jundiaí, São Paulo. The subjects underwent a detailed clinical examination and neuropsychometric evaluation. All subjects with AD met DSM-IV and NINCDS-ADRDA criteria. Ten patients received a diagnosis of AD and 10 were healthy subjects, forming the control group (CG). Results: All participants correctly answered the phrase from the MMSE (phrase 1). The MoCA phrases (phrases 2 and 3) were correct in 80% and 90%, respectively in the CG and in 40% and 50%, respectively in the AD group. Conclusions: The MoCA test proved more effective in evaluating the echoic behavior in AD patients compared to the MMSE. The simpler phrase repetition task in the MMSE was found to be less sensitive in detecting mild language decline in AD patients.

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