scholarly journals The correlation between the cerebroplacental ratio and fetal arterial blood gas in appropriate-for-gestational-age fetuses: A cross-sectional study

2021 ◽  
pp. 821-826
Author(s):  
Ashraf Jamal ◽  
Vajiheh Marsoosi ◽  
Fatemeh Sarvestani ◽  
Neda Hashemi
Keyword(s):  
Gestational Age ◽  
Neonatal Intensive Care ◽  
Fetal Distress ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Emergency Cesarean ◽  
Appropriate For Gestational Age ◽  
Adverse Pregnancy

Background: The cerebroplacental ratio (CPR) is an important index for predicting adverse pregnancy outcomes in small-for-gestational-age and appropriate-forgestational-age fetuses. Objective: To find out whether there is an association between the CPR level and the blood cord gases analysis in appropriate for gestational age fetuses. Materials and Methods: This cross-sectional study included 347 pregnant women at the gestational age of 37-40 wk. Patients had an appropriate-for-gestational-age fetus confirmed from their first ultrasonography results. Participants were divided into two groups based on their CPR, measured before delivery. Finally, after delivery, arterial blood gas level and the incidence of emergency cesarean section, intrapartum fetal distress and neonatal intensive care unit admissions were compared between the two groups. Results: Fifty-four (15.6%) cases had a CPR below the detection limit of the assay. The incidence of fetal distress, emergency cesarean section, neonatal hospitalization in the neonatal intensive care unit, and pH < 7.2 were significantly lower in women with CPR ≥ 0.67 multiples than in women with a CPR < 0.67 multiples of the median. Conclusion: The third-trimester CPR is an independent predictor of stillbirth and perinatal mortality and morbidity. The role of UA/MCA Doppler and the CPR in assessing the risk of adverse pregnancy outcomes should be evaluated prospectively. Key words: Umbilical cord blood, Color Doppler ultrasonography, Gestational age.

Impact of paternal presence and parental social-demographic characteristics on birth outcomes

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Amruta A. Bamanikar ◽  
Shetal Shah ◽  
David Aboudi ◽  
Soumya Mikkilineni ◽  
Clare Giblin ◽  
...  
Keyword(s):  
Birth Outcomes ◽  
Gestational Age ◽  
Neonatal Intensive Care ◽  
Post Partum ◽  
Birth Certificate ◽  
Cross Sectional Study ◽  
Environment Impact ◽  
Cross Sectional ◽  
Post Partum Period ◽  
Paternal Race

Abstract Objectives Maternal race, marital status, and social environment impact risk of preterm delivery and size for gestational age. Although some paternal characteristics such as age are associated with pregnancy outcomes, the influence of the paternal presence, race/ethnicity and adverse life events is not well known. The objective of the study was to assess birth outcomes in mothers with a paternal presence compared to those without during the post-partum period. The secondary aim was to determine whether paternal race is associated with birth outcomes. Methods This was a cross-sectional study using parental surveys linked with birth certificate data from 2016 to 2018. Adverse birth composite outcomes (ABCO) including small for gestational age (SGA), prematurity or neonatal intensive care unit admission (NICU) were assessed. Results A total of 695 parents were analyzed (239 single mothers and 228 mother-father pairs). Compared to mothers with a father present, mothers without a father present exhibited increased odds of ABCO, prematurity and NICU. Non-Hispanic Black fathers had increased odds of ABCO and NICU compared to Non-Hispanic Whites (NHW). Hispanic fathers had increased odds of NICU compared to NHW. Conclusions Paternal absence in the post-partum period and paternal race were both independently associated with ABCO and NICU. Assessment of paternal presence and paternal race in clinical practice may help identify opportunities for additional support necessary to optimize birth outcomes.

scholarly journals Fetal foot length for assessment of gestational age: a cross sectional study

2021 ◽  
Vol 10 (8) ◽  
pp. 3153
Author(s):  
Vaibhav Sharma ◽  
Ruchi Saxena ◽  
Priyanka Gaur
Keyword(s):  
Gestational Age ◽  
Abdominal Ultrasound ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Maternal Characteristics ◽  
Foot Length ◽  
Adverse Pregnancy ◽  
The Relationship ◽  
Singleton Pregnancies

Background: Fetal age actually begins at conception and an equivalent term is conceptional age. Uncertain gestational age (GA) has been associated with adverse pregnancy outcomes independent of maternal characteristics. The objective was to evaluate the accuracy of fetal foot length (FFL) in estimation of gestational age.Methods: It was a cross sectional study. Trans abdominal ultrasound on 150 pregnant women with normal singleton pregnancies between 16 to 40 weeks was done to measure FFL. The relationship between GA and FFL was analysed by simple linear regression.Results: A linear relationship was demonstrated between FFL and GA. (GA (in weeks)=7.490+0.393×FFL (in mm)) with significant correlation (r=0.985, p<0.001).Conclusions: Ultrasonographic measurement of FFL is a reliable indicator of gestational age and can be a useful alternative to estimate GA when other routine biometric parameters are not conclusive.

scholarly journals Investigation of Frequency of the Lethal Triad and Its 24 Hours Prognostic Value among Patients with Multiple Traumas

2019 ◽  
Vol 7 (6) ◽  
pp. 962-966 ◽  
Author(s):  
Iraj Goli Khatir ◽  
Farzad Bozorgi ◽  
Hesam Ghanbari ◽  
Fatemeh Jahanian ◽  
Mohsen Arabi ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Predictive Value ◽  
Coagulation Factors ◽  
Cross Sectional Study ◽  
Care Plan ◽  
Cross Sectional ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Lethal Triad ◽  
Multiple Traumas

BACKGROUND: Death in multiple trauma (MT) patients is one of the serious concerns of the medical service provider. Any prediction of the likelihood of death on the assessment of the patient's condition is performed using different variables, one of the tools in the triage of patients to determine their condition. AIM: We aimed to investigate the frequency and the predictive value of death in 24 hours triad of death in patients qualified with multiple traumas admitted to Imam Khomeini hospital. METHODS: This was a prospective cross-sectional study to determine the prevalence and predictive value of 24-hour triad of death among patients with MT referred to an emergency department. Three factors including acidosis, hypothermia and coagulopathy and predictive value of 24-hour death were evaluated. Arterial blood gas, oral temperature and blood samples for coagulation factors were analysed. Data were analysed using SPSS version 19. Multivariate analysis (logistic regression) was used to determine the predictive value of the triad of death. RESULTS: A group of 199 MT patients referring to Imam Khomeini hospital during the first 6 months of 2015 were evaluated for the first 24 hours of admission. Logistic regression analysis showed that using the following formula based on the triad of death can predict death in 96% of cases can be based on the triad of a death foretold death upon admission to the emergency room. It should be noted that this prediction tool as 173 people left alive after 24 hours as live predicts (100% correct). CONCLUSION: The triad of death is one of the tools in the triage of patients to determine their condition and care plan to be used, provided valuable information to predict the prognosis of patients with a medical team.

scholarly journals Reference Values of Fetal Peak Systolic Velocity in the Middle Cerebral Artery at 19–40 Weeks of Gestation in Nepalese Population

2014 ◽  
Vol 8 (2) ◽  
pp. 42-45 ◽  
Author(s):  
U Shrestha ◽  
I Shrestha ◽  
RK Ghimire ◽  
S Paudel
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Gestational Age ◽  
Adverse Pregnancy Outcome ◽  
Peak Systolic Velocity ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Systolic Volume ◽  
Serial Measurement ◽  
Adverse Pregnancy

Aims: The purpose of this study was to construct new reference range for fetal middle cerebral artery peak systolic velocity (MCA-PSV) in uncomplicated pregnancy at 19-40 weeks of gestation. Methods: This was a prospective cross-sectional study involving 400 singleton pregnancies between 19 and 40 weeks of gestation without any known risk factors of adverse pregnancy outcome who were referred for routine obstetric examination. The protocol included the doppler examination of fetal middle cerebral artery (MCA) within 2 mm after its origin from the internal carotid artery and data were used to construct the normograms and percentile fitted curves of each doppler parameter for different gestational age. Results: Among 400 singleton uncomplicated pregnancies between 19 and 40 weeks of gestation maximum number of pregnancies (10%) was at 19 weeks of gestation and minimum (2.5%) was at 31 weeks. The fetal peak systolic blood flow in the MCA showed significant correlation with period of gestation. Mean MCA-PSV was 22.35 ± 3.05 at 19 weeks of gestation which increased to 67.73 ± 9.92 at 40 weeks. The MCA-PSV showed continuous increment with increasing gestational age.Conclusions: Continuous increment in the peak systolic volume with advancing gestational age was obtained which was consistent with the previous studies done by various authors. The percentile fitted values and normograms will be valuable for the serial measurement of the peak systolic volume of the middle cerebral artery for complicated pregnancies.Nepal Journal of Obstetrics and Gynaecology / Vol 8 / No. 2 / Issue 16 / July-Dec, 2013 / 42-45 DOI: http://dx.doi.org/10.3126/njog.v8i2.9769  

scholarly journals Changes in Maternal Serum Transforming Growth Factor Beta-1 during Pregnancy: A Cross-Sectional Study

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Mandeep Singh ◽  
Ngozi C. Orazulike ◽  
Jill Ashmore ◽  
Justin C. Konje
Keyword(s):  
Growth Factor ◽  
Gestational Age ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Cross Sectional Study ◽  
Maternal Serum ◽  
Cross Sectional ◽  
Appropriate For Gestational Age ◽  
Growth Factor Beta ◽  
Circulating Levels

Changes in circulating levels of maternal serum transforming growth factor beta-1 (TGF-β1), collected from 98 women (AGA) at different gestational ages (10–38 weeks) were measured and comparisons were made between levels in pregnant and nonpregnant controls and also between 10 women with small-for-gestational age (SGA) and 7 with appropriate-for-gestational age (AGA) fetuses. Maternal serum TGF-β1 levels at all stages of pregnancy were higher than those in normal healthy nonpregnant adults. The mean TGF-β1 levels in SGA pregnancies at 34-week gestation (32.5 + 3.2 ng/mL) were significantly less than those in AGA pregnancies (39.2 + 9.8 ng/mL) while at 38-week gestation, the levels were similar in the two groups (36.04 + 4.3 versus 36.7 + 7.0 ng/mL). This differential change in TGF-β1 levels is probably an important modulating factor in the aetiopathogenesis of abnormal intrauterine fetal growth.

scholarly journals Comparison of bone age in small-for-gestationalage children vs appropriate-for-getational-age children

2010 ◽  
Vol 50 (2) ◽  
pp. 73
Author(s):  
Lionardus Edward ◽  
Sjarif Hidajat Effendi ◽  
Djatnika Setiabudi
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Linear Growth ◽  
Prevalence Ratio ◽  
Bone Age ◽  
Cross Sectional Study ◽  
Healthy Children ◽  
Cross Sectional ◽  
Appropriate For Gestational Age ◽  
Bone Age Delay

BackgroundAbout 10-15% small-for-gestational-age children are in higher risk for having linear growth retardation due to growth hormone-insulin like growth factor 1 axis defect (GH-IGF 1) which causes bone age delay.ObjectivesTo compare bone age in 24-36 month old children born small-for-gestational-age (SGA) to that in children born appropriate-for-gestational-age (AGA).MethodsA cross-sectional study was conducted in Hasan Sadikin General Hospital, Bandung, from January to April 2009.Subjects consisted of50 healthy children of 24-36 months old (25 children born at term, SGA, 25 children born at term, AGA). We compared the appropriateness and delay of bone age between the two groups. ResultsMean bone age in the SGA group was 20.8 (SD 7.7) months, and in the AGA group was 25.7 (SD 7.1) months (P=0.022). Mean bone age deficit was -10.5 (6.5) months in the SGA group and -5.5 (SD 5.7) months in the AGA group (P=0.009). The prevalence ratio was 1.77 (95% CI: 1.19–2.62). Bone age delay was found to be higher in children born SGA than that in children of the other group (23 vs 13). On the contrary, appropriate bone age was found more in children born AGA (12 vs 2) (P=0.002).Conclusion Bone age delay in 24-36 months old children born small-for-gestational-age was found to be higher than in those born appropriate-for-gestational-age.

Prognostic factors in methanol poisoning

2007 ◽  
Vol 26 (7) ◽  
pp. 583-586 ◽  
Author(s):  
H. Hassanian-Moghaddam ◽  
A. Pajoumand ◽  
S.M. Dadgar ◽  
Sh. Shadnia
Keyword(s):  
Mortality Rate ◽  
Cross Sectional Study ◽  
Time Interval ◽  
Poison Center ◽  
Cross Sectional ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Significant Difference ◽  
The Mean ◽  
Mean Time

The aim of this study was to assess the clinical and laboratory factors in methanol poisoned patients to determine the prognosis of their toxicity. This survey was done as a prospective cross-sectional study in methanol-poisoned patients in Loghman-Hakim hospital poison center during 9 months from October 1999—June 2000. During this time 25 methanol-poisoned patients were admitted. The mortality rate was 12 (48%). Amongst survivors, three (23%) of the patients developed blindness due to their poisoning and the other 10 (77%) fully recovered without any complication. The mortality rate in comatose patients was nine (90%) while in non-comatose patients it was three (20%) ( P < 0.001). There was a significant difference in mean pH in the first arterial blood gas of patients who subsequently died (6.82 ± 0.03) and survivors (7.15 ± 0.06) ( P < 0.001, M-W). The mean time interval between poisoning and ED presentation in deceased patients were (46 ± 15.7) hours, in survived with sequelae were (16.7 ± 6.7) and in survived without sequelae were (10.3 ± 7.2) hours ( P < 0.002, K-W). We found no significant difference between the survivors versus the patients who died regarding methanol. Simultaneous presence of ethanol and opium affected the outcome of the treatment for methanol intoxication favourably and unfavourably, respectively. In our study, poor prognosis was associated with pH < 7, coma on admission and >24 hours delay from intake to admission. Human & Experimental Toxicology (2007) 26: 583—586.

scholarly journals Comparison of Serum Triglyceride and Cholesterol Levels in Premature Neonates with or without Respiratory Distress Syndrome (RDS)

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Roya Kelishadi ◽  
Behzad Barekatain ◽  
Atefeh Fatahi
Keyword(s):  
Fatty Acids ◽  
Gestational Age ◽  
Neonatal Intensive Care ◽  
Direct Relationship ◽  
Essential Fatty Acids ◽  
Serum Triglyceride ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Premature Neonates ◽  
Cholesterol Levels

Background. Deficiency or reduced transmission of long-chain fatty acids and essential fatty acids may inhibit lung growth and development. We aimed to evaluate and compare serum triglyceride and cholesterol levels in premature neonates with RDS. Methods. This study is a cross-sectional study performed on premature neonates born in Beheshti Hospital in Isfahan in 2018. Immediately after birth and after umbilical cord clumping, blood samples were taken from the umbilical artery and triglyceride and total cholesterol levels were measured. Those patients with the diagnosis of RDS were transferred to the neonatal intensive care unit (NICU). Data regarding the laboratory results of the lipid profile in patients were compared to that in the other group. Results. A total number of 100 neonates entered the study and were divided into 2 groups. Analysis of gender and mean gestational ages among the two groups showed no significant differences between the groups ( P = 0.84 and P = 0.28 , respectively). Further analysis showed a significant decreased serum cholesterol in the group 1 of patients ( P = 0.01 ), but there were no significant differences between the two groups regarding triglyceride levels ( P = 0.43 ). There was a significant direct relationship between gestational age and serum triglyceride levels in patients with RDS ( r = 0.550 , P < 0.001 ). Conclusion. Here, we indicated significantly lower cholesterol levels in the cord serum of premature neonates with RDS compared to non-RDS premature neonates. Our data also showed a significant direct relationship between gestational age and serum triglyceride levels in patients with RDS. These data were in line with the previous studies.

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