Prevalence and predictors of HIV infection among adults aged 50 years and above in Shinyanga, Iringa and Ruvuma regions of Tanzania

2020 ◽  
Vol 8 (12) ◽  
pp. 492-503
Author(s):  
Mangi Ezekiel ◽  
Lucas E. Matemba ◽  
Idda Mosha ◽  
Mukome Nyamhagatta ◽  
Sharon Lwezaura ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hiv Infection ◽  
Condom Use ◽  
Sexual Intercourse ◽  
Age Groups ◽  
Wealth Quintile ◽  
People Living With Hiv ◽  
Cross Sectional ◽  
Increased Risk ◽  
Study Participants

Background The UNAIDS Report on the global AIDS report show  that 35.3 million people living with HIV globally, out of that an estimated 3.6 million are people aged 50 years or above. Methods This was a cross sectional study conducted in Shinyanga, Iringa and Ruvuma regions in Tanzania aiming at determining prevalence and risk factors for HIV infection among elderly people aged 50 years and above. Random sampling was employed to select 2,214 participants. HIV testing to consenting participants was conducted and a survey was used to collect data on socio-demographic information, medical conditions and sexual behavioral factors.   Results The overall prevalence of HIV infection among study participants was 4.4% (95% CI=3.6-5.4). The prevalence was higher among females compared to males. Majority of study participants were aware of HIV, transmission and preventive measures. Few respondents knew that a person could be infected through anal sex. More than half of the participants prefer HIV status to remain confidential. A significantly larger proportion (24.2%) of males reported to ever use a condom during their last sexual intercourse compared to females (9.5%). Compared to older age groups, respondents aged 50-59 years were significantly more likely to report condom use during last sexual intercourse. Being in the fourth of highest wealth quintile, ever use of condom, condom use during last sexual encounter, having 2 or more partners in the last one year were associated with an increased risk of HIV infection. Conclusion The high prevalence of HIV among study participants highlights the prerequisite for increased attention to address underlying risk factors for HIV infection among adults.  

scholarly journals The use of inappropriate anal douching tool associates with increased HIV infection among men who have sex with men: a cross-sectional study in Shenyang, China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhen Xing Chu ◽  
Guangquan Shen ◽  
Qinghai Hu ◽  
Hongyi Wang ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hiv Infection ◽  
Sexual Behaviors ◽  
Anal Intercourse ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Anal Sex ◽  
Cross Sectional ◽  
Increased Risk ◽  
Sex With Men

Abstract Background Rectal douching (RD) is widely practiced by men who have sex with men (MSM), and is associated with increased risk of HIV infection. However, the mechanism of how RD increases the risk of HIV infection is not well understood, and there is limited data on RD behavior in MSM practicing anal sex in China. We examine the purpose of RD, its timing in relation to anal sex, the types of RD products used, and risky sexual behaviors among MSM reporting anal sex. Methods Between August 2017 and December 2018, a cross-sectional study was conducted among adult MSM in Shenyang, China. Data were collected on demographics, sexual behaviors, and RD for the most recent sexual intercourse by means of interviewer-administered face-to-face questionnaires. Blood samples were collected to test for antibodies to HIV and syphilis. Multivariable logistic regression models were used to assess the risk factors associated with HIV infection. Results A total of 515 eligible MSM participated in this survey (median age: 31 years). During the most recent anal intercourse, 28.3% (146/515) had condomless receptive anal intercourse (CRAI), 21.4% (110/515) practiced serosorting, and more than half (61.6%, 317/515) reported RD before or after anal sex. Of those practicing RD, 96.8% (307/317) conducted RD before sex, while 62.5% (198/317) conducted RD after sex. The douching devices used were primarily shower hoses (85.3%, 262/307), and relatively few MSM used commercial RD products (8.1%, 25/307) before sex. The prevalence of HIV-1 and syphilis was 11.7% and 13.2%, respectively. HIV infection was positively associated with RD, practicing RD before sex, the interaction between RD and CRAI using a shower hose for RD and other risk factors, practicing RD after sex, CRAI, using nitrite inhalants, main sexual role with males as bottom and syphilis infection. Conclusions RD is popular among Chinese MSM. Improper noncommercial RD tools use (such as shower hose), the interaction effect between RD and CRAI associated with HIV infection. Public health workers and the MSM community should publicize scientific knowledge and prevention approaches relating to RD and HIV transmission to MSM. We recommend that further studies should be conducted to understand the detailed mechanism between RD and increased HIV prevalence.

scholarly journals Prevalence and Risk Factors of Untreated Thyroid Dysfunctions in the Older Caucasian Adults: Results of Polsenior 2 Survey

2021 ◽  
Author(s):  
Piotr Kocelak ◽  
Malgorzata Mossakowska ◽  
Monika Puzianowska-Kuznicka ◽  
Krzysztof Sworczak ◽  
Adam Wyszomirski ◽  
...  
Keyword(s):  
Risk Factors ◽  
Thyroid Dysfunction ◽  
Population Based ◽  
Community Dwelling ◽  
Medical Services ◽  
Design Data ◽  
Cross Sectional ◽  
Multidisciplinary Study ◽  
Increased Risk ◽  
Study Participants

Abstract Background: To determine the prevalence of treated and untreated thyroid dysfunction and to identify factors associated with increased risk of undiagnosed thyroid dysfunction in older adults.Methods The population of 5987 community-dwelling Polish Caucasian seniors aged 60 years and above who participated in the PolSenior 2 study (2018 – 2019). Population-based cross-sectional multidisciplinary study in design. Data from structured questionnaires, geriatric tests and scales were obtained from all study participants who underwent anthropometric and blood pressure measurements during three home visits. Assessment of thyroid function was based on TSH serum measurements.ResultsThe prevalence of thyroid dysfunction in the Polish population aged 60 years or above was estimated at 15.5% (21.5% in women and 7.2% in men), with 3.2% of undiagnosed individuals among them. The prevalence of hypothyroidism and hyperthyroidism in the studied group was 13.9% (19.4% in women and 6.3% in men) and 1.6% (2.1% in women and 0.9% in men) respectively. In multiple regression analysis independent risk factors for thyroid disorders being untreated were older age (> 75 years), male sex, a low education level (primary or lower) and low utilization of medical services.Conclusions One-fifth of Polish Caucasian seniors with hypothyroidism and one-third with hyperthyroidism is untreated. Older, poorly educated and rarely utilizing medical services seniors, especially men, are more frequently untreated for thyroid dysfunction and some of them do not benefit from contemporary achievements of medicine.

scholarly journals Trends and correlates of HIV prevalence among adolescents in South Africa: evidence from the 2008, 2012 and 2017 South African National HIV Prevalence, Incidence and Behaviour surveys

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Musawenkosi Mabaso ◽  
Goitseone Maseko ◽  
Ronel Sewpaul ◽  
Inbarani Naidoo ◽  
Sean Jooste ◽  
...  
Keyword(s):  
South Africa ◽  
Hiv Infection ◽  
Transition To Adulthood ◽  
Educational Institution ◽  
Age Groups ◽  
Hiv Prevalence ◽  
Cross Sectional ◽  
Factors Associated ◽  
Increased Risk ◽  
And Gender

Abstract Background Adolescents are at increased risk of HIV infection compared to other age groups. There is an urgent need for strategic information that will inform programmes to reduce risk and vulnerability to HIV and reverse the pattern of increasing HIV infection as they transition to adulthood. This paper analysed trends and factors associated with HIV prevalence among adolescents in South Africa using the national HIV population-based household surveys conducted in 2008, 2012 and 2017. Methods All three surveys used a multistage cross-sectional design. A trend analysis was conducted to assess the differences in HIV prevalence and covariates overtime using P-trend Chi-squared statistic. Univariate and multivariate logistic regression models were used to determine factors associated with HIV prevalence. Results Overall there was a significant increase in HIV prevalence among adolescents aged 12–19 years from 3.0% (n = 2892) in 2008 to 3.2% (n = 4829) in 2012 and 4.1% (n = 3937) in 2017 (p = 0.031). The odds of being HIV positive among adolescents aged 12–19 years was significantly higher among females [AOR = 2.24; 95% CI (1.73–2.91); p < 0.001] than males, those residing in KwaZulu-Natal province [AOR = 2.01; 95% CI (1.-3.99); p = 0.027] than Northern Cape, and those who did not attend an educational institution and were unemployed [AOR = 2.66; 95% CI (1.91–3.67); p < 0.001] compared to those attending an educational institution. The odds were significantly lower among Whites [AOR = 0.29; 95% CI (0.09–0.93); p = 0.037], Coloureds [AOR = 0.21; 95% CI (0.11–0.37); p ≤ 0.001] and Indian/Asian [AOR = 0.08; 95% CI (0.02–0.34); p = 0.001] population groups than Black Africans. Conclusion The observed increasing trend and gender disparities in HIV prevalence suggests an urgent need for age appropriate and gender specific HIV interventions tailored and targeted at identified drivers of HIV infection among adolescents.

scholarly journals Prevalence and Risk Factors of CoronaVac Side Effects: An Independent Cross-Sectional Study among Healthcare Workers in Turkey

2021 ◽  
Vol 10 (12) ◽  
pp. 2629
Author(s):  
Abanoub Riad ◽  
Derya Sağıroğlu ◽  
Batuhan Üstün ◽  
Andrea Pokorná ◽  
Jitka Klugarová ◽  
...  
Keyword(s):  
Risk Factors ◽  
Side Effects ◽  
Healthcare Workers ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Vaccine Hesitancy ◽  
Public Confidence ◽  
Sectional Study ◽  
Cross Sectional ◽  
Increased Risk

Background: COVID-19 vaccine hesitancy is a serious threat to mass vaccination strategies that need to be accelerated currently in order to achieve a substantial level of community immunity. Independent (non-sponsored) studies have a great potential to enhance public confidence in vaccines and accelerate their uptake process. Methods: A nationwide cross-sectional study for the side effects (SE) of CoronaVac was carried out in February 2021 among Turkish healthcare workers who were recently vaccinated. The questionnaire inquired about local and systemic SEs that occurred in the short-term, within four weeks, following vaccination. Results: A total of 780 healthcare workers were included in this study; 62.5% of them experienced at least one SE. Injection site pain (41.5%) was the most common local SE, while fatigue (23.6%), headache (18.7%), muscle pain (11.2%) and joint pain (5.9%) were the common systemic SEs. Female healthcare workers (67.9%) were significantly more affected by local and systemic SEs than male colleagues (51.4%). Younger age, previous infection, and compromised health status (chronic illnesses and regular medicines uptake) can be associated with an increased risk of CoronaVac SEs; Conclusions: The independent research shows a higher prevalence of CoronaVac SEs than what is reported by phase I–III clinical trials. In general, the results of this study confirm the overall safety of CoronaVac and suggest potential risk factors for its SEs. Gender-based differences and SEs distribution among age groups are worth further investigation.

scholarly journals Beyond biomarkers and towards functional outcomes for adult persons living with HIV. A cross sectional survey in Blantyre Urban, Malawi.

2019 ◽  
Author(s):  
Steven Derrick Manyozo ◽  
Nesto Tarimo ◽  
Gift Kawalazira ◽  
Adamson Sinjani Muula
Keyword(s):  
Risk Factors ◽  
International Classification Of Functioning ◽  
Categorical Variables ◽  
People Living With Hiv ◽  
Cross Sectional ◽  
Mental Functions ◽  
Persons Living With Hiv ◽  
Associated Risk Factors ◽  
Study Participants ◽  
Living With Hiv

Abstract Introduction Despite improvements in survival, reports indicate that people living with HIV are experiencing a range of physical, cognitive, mental and social health-related challenges associated with HIV, comorbidities and aging recently termed ‘disability’. Among adult persons living with HIV in Malawi, the prevalence of disability and associated risk factors are not known. This study was designed to assess the prevalence of impairments, activity limitations and associated risk factors among adults living with HIV in Blantyre urban, Malawi. Methods We conducted a quantitative cross sectional study among adult persons living with HIV in Blantyre urban from March to August 2018. Participants were recruited consecutively from 5 health centers. We used the WHO’s International Classification of Functioning, Disability and Health (ICF) for data collection. Written informed consent was sourced from study participants, permission was granted at each study site and the study received ethics approval from the College of Medicine Research Ethics Committee (COMREC). Descriptive statistics were used to summarize the data. Categorical variables were summarized as frequencies and percentages and continuous variables were summarized using means and standard deviation. Univariable and multivariable logistic regression were used to assess association between presence of disability and selected factors. Odds ratios (OR) and their 95% confidence intervals were calculated. Results Of the 277 participants enrolled in the study, 225 (81%) were female and 52 (19%) were male. The mean age of participants was 37 years ( std. dev 9.5 ). Impairments in mental functions were the most prevalent affecting 118 (43%) study participants. Energy and drive (18%), memory (14%) and sleep (13%) were the most affected mental functions. Impairments in the mental functions, genital urinary, reproductive, digestive, metabolic and endocrine systems were associated with higher odds of disability among the participants. Conclusions Our results indicate a high prevalence of impairments among persons living with HIV. Clinicians and rehabilitation personnel need to be proactive in identifying and managing impairments to promote health among HIV patients.

scholarly journals Prevalence of shisha smoking and risk factors among female adolescents in Iran

2019 ◽  
Author(s):  
Saeed Bashirian ◽  
Majid Barati ◽  
Manoochehr Karami ◽  
Behrooz Hamzeh ◽  
elahe ezati
Keyword(s):  
Risk Factors ◽  
Age Groups ◽  
Educational Interventions ◽  
Cross Sectional Study ◽  
Female Adolescents ◽  
Limited Data ◽  
Cross Sectional ◽  
Western City ◽  
The Mean ◽  
Study Participants

Abstract Background: shisha smoking is on the increase in Iarn, but there are limited data on its use among adolescents. This research purpose is to the survey prevalence of shisha smoking and risk factors among female in Iran. Methods: This was a cross-sectional study . The study participants was 1302. The sampling was multistage random. 12 schools from three sectors of Kermanshah in the western city in Iran( 4 schools from each sector), were selected. Students were in grades 7 to 12. data were collected using questionnaire and analyzed by descriptive statistical methods and Logistic regression test by using SPSS 22 software. Results: The mean (SD) ages of the students and the ages when the participants started SS were 15.22 ± 1.85 and 13.64 (1.64) respectively. 32.4% of the participants ever having used a shisha and 20.4% mentioned they used shisha the last 30 days. Most of the subjects smoked shishas in friends’ houses (45.8%) and with their friends (47.4%). The significantly important factors that affect SS in these age groups were the father's and mother's occupation, family size, living with others, father's education, having a friend who smokes shishas, friends’ encouragement to smoke shisha, and being in a family that smoke shishas. Conclusions: shisha smoking has become a major concern in female . shisha prevention needs extensive studies. Investigation of shisha behavioral factors is essential in designing of educational interventions. Key words: Female, adolescents, student, shisha smoking .

scholarly journals The use of inappropriate anal douching tool associates with increased HIV infection among men who have sex with men: a cross-sectional study in Shenyang, China

2021 ◽  
Author(s):  
ZhenXing Chu ◽  
Guangquan Shen ◽  
Qinghai Hu ◽  
Hongyi Wang ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hiv Infection ◽  
Sexual Behaviors ◽  
Anal Intercourse ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Anal Sex ◽  
Cross Sectional ◽  
Increased Risk ◽  
Sex With Men

Abstract Background: Rectal douching (RD) is widely practiced by men who have sex with men (MSM), and is associated with increased risk of HIV infection. However, the mechanism of how RD increases the risk of HIV infection is not well understood, and there is limited data on RD behavior in MSM practicing anal sex in China. We examine the purpose of RD, its timing in relation to anal sex, the types of RD products used, and risky sexual behaviors among MSM reporting anal sex.Methods: Between August 2017 and December 2018, a cross-sectional study was conducted among adult MSM in Shenyang, China. Data were collected on demographics, sexual behaviors, and RD for the most recent sexual intercourse by means of interviewer-administered face-to-face questionnaires. Blood samples were collected to test for antibodies to HIV and syphilis. Multivariable logistic regression models were used to assess the risk factors associated with HIV infection.Results: A total of 515 eligible MSM participated in this survey (median age: 31 years). During the most recent anal intercourse, 28.3% (146/515) had condomless receptive anal intercourse (CRAI), 21.4% (110/515) practiced serosorting, and more than half (61.6%, 317/515) reported RD before or after anal sex. Of those practicing RD, 96.8% (307/317) conducted RD before sex, while 62.5% (198/317) conducted RD after sex. The douching devices used were primarily shower hoses (85.3%, 262/307), and relatively few MSM used commercial RD products (8.1%, 25/307) before sex. The prevalence of HIV-1 and syphilis was 11.7% and 13.2%, respectively. HIV infection was positively associated with RD, practicing RD before sex, the interaction between RD and CRAI using a shower hose for RD and other risk factors, practicing RD after sex, CRAI, using nitrite inhalants, main sexual role with males as bottom and syphilis infection.Conclusions: RD is popular among Chinese MSM. Improper noncommercial RD tools use (such as shower hose), the interaction effect between RD and CRAI associated with HIV infection. Public health workers and the MSM community should publicize scientific knowledge and prevention approaches relating to RD and HIV transmission to MSM. We recommend that further studies should be conducted to understand the detailed mechanism between RD and increased HIV prevalence.

scholarly journals Community‐Acquired Pneumonia and Risk of Cardiovascular Events in People Living With HIV

2020 ◽  
Vol 9 (23) ◽  
Author(s):  
Jerry S. Zifodya ◽  
Meredith S. Duncan ◽  
Kaku A. So‐Armah ◽  
Engi F. Attia ◽  
Kathleen M. Akgün ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hiv Infection ◽  
Cox Regression ◽  
Community Acquired Pneumonia ◽  
People Living With Hiv ◽  
Hiv Status ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
Increased Risk ◽  
Living With Hiv

Background Hospitalization with community‐acquired pneumonia (CAP) is associated with an increased risk of cardiovascular disease (CVD) events in patients uninfected with HIV. We evaluated whether people living with HIV (PLWH) have a higher risk of CVD or mortality than individuals uninfected with HIV following hospitalization with CAP. Methods and Results We analyzed data from the Veterans Aging Cohort Study on US veterans admitted with their first episode of CAP from April 2003 through December 2014. We used Cox regression analyses to determine whether HIV status was associated with incident CVD events and mortality from date of admission through 30 days after discharge (30‐day mortality), adjusting for known CVD risk factors. We included 4384 patients (67% [n=2951] PLWH). PLWH admitted with CAP were younger, had less severe CAP, and had fewer CVD risk factors than patients with CAP who were uninfected with HIV. In multivariable‐adjusted analyses, CVD risk was similar in PLWH compared with HIV‐uninfected (hazard ratio [HR], 0.89; 95% CI, 0.70–1.12), but HIV infection was associated with higher mortality risk (HR, 1.49; 95% CI, 1.16–1.90). In models stratified by HIV status, CAP severity was significantly associated with incident CVD and 30‐day mortality in PLWH and patients uninfected with HIV. Conclusions In this study, the risk of CVD events during or after hospitalization for CAP was similar in PLWH and patients uninfected with HIV, after adjusting for known CVD risk factors and CAP severity. HIV infection, however, was associated with increased 30‐day mortality after CAP hospitalization in multivariable‐adjusted models. PLWH should be included in future studies evaluating mechanisms and prevention of CVD events after CAP.

scholarly journals Standardized Comparison of Cardiovascular Risk Factors Prevalence in Spanish Women and Men Living with HIV and in the General Population

2021 ◽  
Vol 11 (11) ◽  
pp. 1085
Author(s):  
Anna Camps-Vilaró ◽  
Silvia Pérez-Fernández ◽  
Isaac Subirana ◽  
Ramon Teira ◽  
Vicente Estrada ◽  
...  
Keyword(s):  
Risk Factors ◽  
General Population ◽  
Direct Method ◽  
Age Groups ◽  
People Living With Hiv ◽  
Population Cohort ◽  
Increased Risk ◽  
Significant Difference ◽  
General Population Cohort ◽  
Living With Hiv

People living with HIV (PLWH) have an increased risk of cardiovascular (CV) disease, likely due to a higher prevalence of CV risk factors. We compared the age-standardized prevalence and management of CV risk factors in PLWH to that of the general population in Spain. Blood pressure, lipid, glucose, and anthropometric profiles were cross-sectionally compared along with the treatment of hypertension, dyslipidemia, and diabetes in a general population cohort and a PLWH cohort. Prevalence rates were standardized by the direct method by 10-year age groups in European standard populations and stratified by gender. We included 47,593 individuals aged 35 to 74 years, 28,360 from the general population cohort and 19,233 from the PLWH cohort. Compared to the general population, PLWH had a higher concentration of triglycerides (>35 mg/dL in women and >26 mg/dL in men) and a higher prevalence of smoking (>23% and >17%) and diabetes (>9.9% and >8.5%). The prevalence of treated diabetes, hypertension, and dyslipidemia were up to three-fold lower in both women and men living with HIV. There was a significant difference in PLWH compared to the general population in the lipid, glucose, and anthropometric profile. In addition, PLWH were less often treated for diagnosed diabetes, hypertension, and dyslipidemia.

scholarly journals Atherosclerosis in subjects newly diagnosed with human immunodeficiency virus infection

2018 ◽  
Vol 38 (4) ◽  
Author(s):  
Tatiana V. Kirichenko ◽  
Veronika A. Myasoedova ◽  
Tatiana E. Shimonova ◽  
Alexandra A. Melnichenko ◽  
Dmitri Sviridov ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hiv Infection ◽  
Surrogate Marker ◽  
Density Lipoprotein ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Control Group ◽  
Newly Diagnosed ◽  
Cross Sectional ◽  
Increased Risk

HIV infection is associated with the increased risk of cardiovascular disease (CVD), even in patients successfully treated with the combination antiretroviral therapy (cART). However, the relationship between HIV, cART, and pathogenesis of CVD remains controversial. In the present study, we evaluated the carotid intima–media thickness (CIMT), a surrogate marker of atherosclerosis, in HIV-infected subjects receiving or not receiving cART. One hundred nine newly diagnosed HIV-infected subjects and one hundred nine uninfected age-matched controls (all males) without the history of CVD, hypertension, or diabetes were recruited into the present study. Cross-sectional analysis at baseline (BL) showed significantly increased levels of triglycerides (TG) and decreased levels of high-density lipoprotein (HDL) in HIV-infected subjects, indicating that these risk factors for CVD appeared during the undiagnosed period of HIV infection. Nevertheless, no differences in CIMT were detected between the groups, suggesting that these risk factors were yet to be translated into the clinical disease. The prospective arm of the study, which included 37 HIV-infected and 23 uninfected subjects, showed higher CIMT increase in HIV-infected group than in control group (P=0.0063). This difference was significant for both cART-treated (P=0.0066) and untreated (P=0.0246) subgroups relative to the uninfected subjects, but no difference was found between the HIV-infected subgroups. These results suggest that cART does not reverse the HIV-induced increase of CIMT. The present study demonstrates that the progression of atherosclerosis is accelerated in HIV-infected subjects regardless of treatment.

Sign in / Sign up

Export Citation Format

Share Document