scholarly journals Cancer preventive effect of recombinant TRAIL by ablation of oncogenic inflammation in colitis-associated cancer rather than anticancer effect

Oncotarget ◽  
2017 ◽  
Vol 9 (2) ◽  
pp. 1705-1716 ◽  
Author(s):  
Joo-Young Kim ◽  
Young-Mi Kim ◽  
Jong-Min Park ◽  
Young Min Han ◽  
Kang Choon Lee ◽  
...  
Keyword(s):  
Preventive Effect ◽  
Anticancer Effect ◽  
Recombinant Trail

scholarly journals P071 Cancer preventive effect of recombinant TRAIL by ablation of oncogenic inflammation in colitis-associated cancer rather than anticancer effect

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S128-S129
Author(s):  
K B Hahm ◽  
J M Park ◽  
Y M Han ◽  
S Hong ◽  
K C Lee
Keyword(s):  
Preventive Effect ◽  
Anticancer Effect ◽  
Recombinant Trail

Biometrological assessment of the preventive effect of a miconazole spray powder on athlete's foot

1996 ◽  
Vol 21 (5) ◽  
pp. 344-346 ◽  
Author(s):  
G.E. PIERARD ◽  
R. WALLACE ◽  
P. DE DONCKER
Keyword(s):  
Preventive Effect ◽  
Athlete’S Foot

Preventive Effect of Both Vitamin C and E on Sperm Abnormalities Caused by Nicotine in Male Albino Mice

2017 ◽  
Vol 2017 (Special-2) ◽  
pp. 152-160
Author(s):  
Galawezh Obaid Othman ◽  
◽  
Nadhum jalal Esmaeil ◽  
Keyword(s):  
Vitamin C ◽  
Preventive Effect ◽  
Sperm Abnormalities ◽  
Albino Mice

CARBOHYDRATE PRODUCT FOR THERAPEUTIC AND PROPHYLACTIC PURPOSES

2020 ◽  
pp. 89-94
Author(s):  
Khvorova L.S. ◽  
Byzov V.A.
Keyword(s):  
Antioxidant Activity ◽  
Uric Acid ◽  
Phenolic Compounds ◽  
Mental Stress ◽  
The Body ◽  
Hot Water ◽  
Preventive Effect ◽  
Activity Inhibition ◽  
Medicinal Properties ◽  
Simple Carbohydrates

The article is devoted to the creation of a carbohydrate product with rosehip extract in the form of sweets (glucose Fudge) with a therapeutic and preventive effect aimed at restoring the body of people exposed to intense physical and mental stress and the effects of damaging environmental factors. As carbohydrates in the recipe, simple carbohydrates (glucose) and complex carbohydrates in the form of starch molasses containing (maltose, tri - Tetra - sugars, dextrins) are used. Glucose in the formulation is the main energy ingredient, sweetener and structure-forming component that gives the product a solid consistency due to crystallization. The medicinal effect of the product is provided by rosehip extract. Numerous published studies have established its vitamin, immunostimulating and antioxidant activity, inhibition of uric acid formation and obesity, which are associated with flavonoids, other phenolic compounds, and vitamins. The list of medicinal properties of rosehip extract shows the feasibility of using it in additional nutrition of people in order to prevent diseases. For the formulation of our sweets, the extraction of crushed rosehip fruits was carried out three times with hot water at a temperature of 65-700C, followed by concentration of the extract under vacuum to 25-30% SV. The resulting extract-concentrate was introduced into the formulation in a dosage of 5.5% SV per 100 g of SV glucose Fudge, which provided the necessary dosage for the product when used from 3 (for children) to 10 sweets a day (for adults) for the prevention of colds.

The Preventive Effect of Fig Leaves’s (Ficus carica L.) towards Colon Histopathological Feature and IL-6 Serum Level on Ulcerative Colitis Induced Mice

2016 ◽  
Vol 1 (4) ◽  
Author(s):  
Hartini Tiono
Keyword(s):  
Ulcerative Colitis ◽  
Serum Level ◽  
Interleukin 6 ◽  
Methanolic Extract ◽  
Chronic Inflammatory Disease ◽  
Control Group ◽  
Preventive Effect ◽  
Histopathological Feature ◽  
Group I ◽  
Control Group Group

Ulcerative colitis is a chronic inflammatory disease mainly affects sigmoid colon and rectum. The inflammation process will activate NF-κB and leads to proinflamatory cytokine release such as Interleukin-6 (IL-6). Fig leaves contain a high level of flavonoid which can prevent NF-κB activation, and further inhibits IL-6 secretion. This research aims to see the preventive effect of methanolic extract of fig leaves towards colon histopathological feature and IL-6 serum level on ulcerative colitis induced mice. Balb/C male mice were randomly assigned into 5 groups (n=5). The treatment groups were dextran suphate sodium (DSS) control group (group I), methanolic extract of Fig leaves dose 28 mg/ day control group (group II), and methanolic extract of Fig leaves dose 7 mg/ day (group III), 14 mg/ day (group IV), and 28 mg/ day (group V) for 14 days, which at the 8th till 14th day were given DSS to induce colitis. The results showed that both of colon mucosal damage and IL-6 serum level of group I were significantly different from other groups (p=0,029). In  conclusion, the methanolic extract of Fig leaves can improve colon mucous damage and decrease IL-6 serum level on ulcerative colitis-induced mice. Keywords: ulcerative colitis, fig leaves, colon mucousal damage, interleukin-6

ANTICANCER EFFECT OF UVARIA GENUS

2014 ◽  
pp. 98-101
Author(s):  
Thi Bich Hien Le ◽  
Viet Duc Ho ◽  
Thi Hoai Nguyen
Keyword(s):  
Biological Activities ◽  
Current Trend ◽  
Healthcare Systems ◽  
Chemical Compositions ◽  
Cancer Therapies ◽  
Pharmacological Effects ◽  
Anticancer Effect ◽  
Anti Cancer ◽  
Tropical Areas ◽  
Cancer Activity

Nowadays, cancer treatment has been a big challenge to healthcare systems. Most of clinical anti-cancer therapies are toxic and cause adverse effects to human body. Therefore, current trend in science is seeking and screening of natural compounds which possess antineoplastic activities to utilize in treatment. Uvaria L. - Annonaceae includes approximately 175 species spreading over tropical areas of Asia, Australia, Africa and America. Studies on chemical compositions and pharmacological effects of Uvaria showed that several compound classes in this genus such as alkaloid, flavonoid, cyclohexen derivaties, acetogenin, steroid, terpenoid, etc. indicate considerable biological activities, for example anti-tumor, anti-cancer, antibacterial, antifungal, antioxidant, etc. Specifically, anti-cancer activity of fractions of extract and pure isolated compounds stands out for cytotoxicity against many cancer cell lines. This study provides an overview of anti-cancer activity of Uvaria and suggests a potential for further studies on seeking and developing novel anti-cancer compounds. Key words: Anti-cancer, Uvaria.

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