scholarly journals Parameters of the oxidative-reduction system of the homeostasis in female transplant patients with tumors of the reproductive system treated with hyperbaric oxygen therapy

2019 ◽  
Vol 11 (4) ◽  
pp. 290-300
Author(s):  
A. V. Babkina ◽  
M. Sh. Khubutiya ◽  
O. A. Levina ◽  
A. K. Evseev ◽  
A. K. Shabanov ◽  
...  
Keyword(s):  
Hyperbaric Oxygen ◽  
Postoperative Period ◽  
Reproductive System ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
The Body ◽  
Antioxidant Systems ◽  
Complex Treatment ◽  
Transplant Patients

Introduction. Studies on the effects of hyperbaric oxygenation have often been represented as animal model experiments. Currently, the number of studies on the use of hyperbaric oxygen therapy in the post-transplant period in humans is growing. The need in investigating the efficacy of hyperbaric oxygen therapy in the postoperative period in female transplant patient with tumors of the reproductive system is dictated by time.The aim of the study was to evaluate the efficacy of hyperbaric oxygen therapy in the complex treatment of transplant patients at an early stage of the postoperative period.Material and methods. We have studied the course of an early postoperative period in 8 female transplant patients with reproductive system tumors treated in N.V. Sklifosovsky Research Institute for Emergency Medicine, using hyperbaric oxygenation. The hyperbaric oxygen therapy sessions were provided in a single-patient hyperbaric chamber at 1.2–1.6 ATA for 40 minutes. The status of the redox homeostasis system was assessed based on the data of the platinum electrode open circuit potential measured in blood plasma by using the potentiometric method; and the blood plasma antioxidant activity was assessed by cyclic voltammetry.Results. The analysis of the results showed that there was a direct relationship indicating the positive effect of hyperbaric oxygen therapy on the balance status of the pro- and antioxidant systems of the body, and on the improvement of blood counts.Conclusion. The early inclusion of hyperbaric oxygen therapy in the complex treatment of transplant patients with tumors of the reproductive system contributes to a more rapid recovery of pro- and antioxidant systems of the body, blood counts.

scholarly journals Research on the Possibility of Treating Streptococcal Infections with Hyperbaric Oxygenation

2020 ◽  
Vol 70 (1) ◽  
pp. 43-46
Author(s):  
Władysław Wolański
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
Lethal Effect ◽  
Streptococcal Infections ◽  
Group A

AbstractThe aim of the study was to determine the effect of the application of hyperbaric oxygen therapy on the course of an infection with group A type T-3 hemolytic β streptococcus. Experiments were carried out on Porton white mice and in vitro blood plates. General and local infections with streptococci were induced in animals. The infected animals were treated with hyperbaric oxygenation. The lethal effect of infection was significantly inhibited using hyperbaric oxygenation on the first and second day following the infection.

Hyperbaric Oxygen Therapy and Its Suitability as an Adjuvant for Treatment of Covid-19 Patients: A Review

2021 ◽  
Vol 12 (4) ◽  
pp. 2548-2556
Author(s):  
Sameera Dawar ◽  
Meena Jain
Keyword(s):  
Mechanical Ventilation ◽  
Oxygen Saturation ◽  
Hyperbaric Oxygen ◽  
Basic Principle ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Delivery ◽  
Atmospheric Pressure ◽  
Oxygen Therapy ◽  
Tissue Oxygenation ◽  
The Body

The outbreak of the SARS CoV2 ' pandemic' is believed to have originated in Wuhan in 2019 as a spread from bats to humans. It is a highly communicable infection-causing rapid human to human transmission of the virus by virtue of its infectious and nature. The virus has affected millions of people worldwide, with numbers still rising with each passing day. Depleting oxygen saturation levels is amongst the prime concerns in the majority of infected patients. Nasal prongs, face masks, mechanical ventilation and membrane (ECMO) are the commonly used modes of oxygen delivery in such patients. These methods though mostly successful, at times fail to restore the depleting oxygen levels to normal. oxygen therapy (HBOT) involves the administration of 100% O2 in a special chamber whose pressure is maintained at a level greater than 1 ATP. The main purpose for raising the pressure within the chamber is that as the atmospheric pressure increases, the saturation levels of oxygen in the blood also increase, which eventually result in increased overall tissue oxygenation. This article provides a systematic and wholesome review on the basic principle of oxygen therapy, its effects on the body at a microscopic and macroscopic level, its various uses and its suitability as an for the treatment of select COVID-19 infected patients.

scholarly journals HISTORICAL DEVELOPMENT OF THE HYPERBARIC OXYGENATION

2021 ◽  
Vol 27 (2) ◽  
pp. 3772-3777
Author(s):  
Krasimira Tsankova ◽  
◽  
Mila Dimitrova ◽  
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Historical Development ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
The Past ◽  
History Of ◽  
Hyperbaric Medicine ◽  
Physical Laws ◽  
Based Medicine

Background: Hyperbaric oxygenation (HBO) is a treatment in which a patient breathes near 100% oxygen within a chamber at a pressure greater than one atmosphere absolute (ATA). The development of hyperbaric medicine is continuous and associated with the history of underwater activities, the development of physical laws and physiological mechanisms of breathing. Purpose: The aim of this article is to present the development of hyperbaric oxygenation internationally and nationally. Materials and Methods: We have conducted a literature review of the published works on hyperbaric oxygen therapy (HBOT) during the last 100 years. Our survey includes scientific reports and books in English and Bulgarian. Results: Three main periods of the historical development of HBOT can be defined. In the past, HBO did not have much scientific support but is extensively used in the field of medicine. We observed an increase in scientific interest in HBO during the last two decades both in our country and worldwide. The majority of the reviewed articles contained information about different aspects of HBO as clinical uses, effects, risks. HBOT has been used as a primary and adjuvant treatment for a variety of diseases for nearly 50 years in Bulgaria. The main areas of application and researches of hyperbaric oxygen therapy include diving diseases, intoxications, traumatic injuries, soft tissue infections, diabetic foot, hearing loss, some neurological disorders, etc. Conclusion: Over the past decades, hyperbaric oxygen therapy has grown rapidly worldwide in accordance with evidence-based medicine methods, and future developments to expand the knowledge are perspective.

scholarly journals Hyperbaric Oxygenation as a Possible Therapy of Choice for Infertility Treatment

2006 ◽  
Vol 6 (2) ◽  
pp. 21-24 ◽  
Author(s):  
Ana Mitrović ◽  
Branka Nikolić ◽  
Svetlana Dragojević ◽  
Predrag Brkić ◽  
Aleksandar Ljubić ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
Endometrial Thickness ◽  
Color Doppler ◽  
Endometrial Receptivity ◽  
Doppler Flowmetry ◽  
Randomised Study

Endometrial sonographic and color doppler features can be used to predict the occurrence of pregnancy in natural or stimulated cycles. Implantation will usually only take place if the endometrium has reach a certain stage of vascularisation and development. The aim of this study was to evaluate endometrial development -- endometrial thickness and reflectivity , subendometrial, endometrial and uterine perfusion, after hyperbaric oxygenation, using transvaginal color doppler. During a three years period 32 women with unexplained infertility were entered into a randomised study. The patients were treated in multiplaced HAUX chamber at pressure of 2.3 ATA during 70 minutes, 7 days consecutively beginning with day 5th of menstrual cycle. The evaluation of effects of hyperbaric oxygen therapy was carried out by transvaginal color doppler sonography which was continuously used starting from 8th day of menstrual cycle until the ovulation in the cycles when the therapy was applied , one month before and one month after the therapy. Folliculometry in the cycles when hyperbaric oxygen therapy at 2.3 ATA was applied, indicated an excellent response of endometrium. Thickness of endometrium at the time of ovulation was 11.0 +/- 2.6 mm. Desirable quality of endometrium was significantly better in the cycle when HBO therapy had been applied (p< 0.001). The doppler flowmetry of the uterine arteries indicated that the uterine blood vessel resistance was slightly higher than expected. Mapping of subendometrial blood vessels in the cycles covered by hyperbaric oxygen therapy showed the intensive capillary network of endometrium with low resistance Ri< 0.45. The oxygen used under higher pressure -- oxygen as a drug , may have an extraordinary significance for better outcome of pregnancy implantation by improving endometrial receptivity. If endometrial receptivity is conditioned by adequate vascularisation and oxygenation, then hyperbaric oxygen therapy is the treatment of choice.

scholarly journals Integrative Role of Hyperbaric Oxygen Therapy on Healthspan, Age-Related Vascular Cognitive Impairment, and Dementia

2021 ◽  
Vol 2 ◽  
Author(s):  
Priya Balasubramanian ◽  
Jordan Delfavero ◽  
Adam Nyul-Toth ◽  
Amber Tarantini ◽  
Rafal Gulej ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Vascular Cognitive Impairment ◽  
The Body ◽  
World Population ◽  
Age Related

Growing life expectancy will contribute to the on-going shift towards a world population increasingly comprised of elderly individuals. This demographic shift is associated with a rising prevalence of age-related diseases, among all age-related pathologies it has become crucial to understand the age-associated cognitive changes that remain a major risk factor for the development of vascular cognitive impairment and dementia (VCID). Furthermore, age-related Alzheimer’s disease and other neurogenerative diseases with vascular etiology are the most prominent contributing factors for the loss of cognitive function observed in aging. Hyperbaric Oxygen Therapy (HBOT) achieves physiologic effects by increasing oxygen tension (PO2), raising oxygen tissue levels, decreasing intracranial pressure and relieving cerebral edema. Many of the beneficial effects of HBOT exert their protective effects at the level of the microcirculation. Furthermore, the microcirculation’s exquisite pervasive presence across every tissue in the body, renders it uniquely able to influence the local environment of most tissues and organs, including the brain. As such, treatments aimed at restoring aging-induced functional and structural alterations of the cerebral microcirculation may potentially contribute to the amelioration of a range of age-related pathologies including vascular cognitive impairment, Alzheimer’s disease, and vascular dementias. Despite the presented evidence, the efficacy and safety of HBOT for the treatment of age-related vascular cognitive impairment and dementia remains understudied. The present review aims to examine the existing evidence indicative of a potential therapeutic role for HBOT-induced hyperoxia against age-related cerebromicrovascular pathologies contributing to cognitive impairment, dementia and decreased healthspan in the elderly.

scholarly journals Clinical Observation of Hyperbaric Oxygen Therapy in Patients with Craniocerebral Trauma

2014 ◽  
Vol 3 ◽  
pp. 14
Author(s):  
Shiqiang Wang
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Craniocerebral Trauma ◽  
The Body ◽  
Duration Of Treatment ◽  
The Difference ◽  
Gcs Score ◽  
Symptoms And Signs ◽  
Better Than

<p><strong>Objective: </strong>To review and analyze the clinical effect of hyperbaric oxygen therapy in the treatment of craniocerebral trauma, and to provide reference for the treatment of craniocerebral trauma. <strong>Method: </strong>From January 2009 to April 2014, we treated 287 cases of patients with craniocerebral trauma, on the basis of conventional treatment, the use of hyperbaric oxygen therapy and assessment for therapeutic effect. <strong>Results</strong><strong>: </strong>After hyperbaric oxygen therapy, patients with GCS score and GOS levels were significantly improved, compared with before treatment, the difference was statistically significant (<em>p</em> &lt; 0.05); effect of the treatment of patients with 2−3 courses of treatment was better than patients receive more than 3 courses of treatment (<em>p</em> &lt; 0.05). <strong>Conclusion: </strong>Hyperbaric oxygen in the treatment of craniocerebral trauma can effectively improve patient’s symptoms and signs, there are helpful in the recovery of the body function of patients. Hyperbaric oxygen treatment should be carry out as soon as possible with appropriate extending the duration of treatment, as well as reduce the severe disability, death and sequela.</p>

scholarly journals The Importance of Hyperbaric Oxygen Therapy in Patients with Fournier Syndrome.

2019 ◽  
pp. 1-5
Keyword(s):  
Early Detection ◽  
Antibiotic Therapy ◽  
Patient Outcomes ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
Adjunctive Treatment ◽  
Broad Spectrum Antibiotic ◽  
Improve Patient

Abstract Fournier syndrome is a synergistic polymicrobial infection that mainly affects the perianal, perineal and genital regions. It is a relatively rare disease with high mortality and an estimated overall incidence of 1.6/100,000 men. Diagnosis is clinical and an early detection is crucial to improve patient outcomes. Treatment is based on three pillars: initial patient stabilization, broad-spectrum antibiotic therapy and extensive surgical debridement of the entire necrotic area. Currently, hyperbaric oxygen therapy has been used as an adjunctive treatment. This study aimed to report the case of a patient with Fournier syndrome who underwent the three-pillar treatment and also hyperbaric oxygenation with a satisfactory result.

scholarly journals Effects of heparin and hyperbaric oxygenation on necrosis reduction in an animal model for degloving injuries

2017 ◽  
Vol 44 (1) ◽  
pp. 64-71
Author(s):  
DOUGLAS NEUMAR MENON ◽  
LETÍCIA TEIXEIRA ◽  
NATALHA BRISTOT PAUROSI ◽  
MARCIO EDUARDO BARROS
Keyword(s):  
Animal Model ◽  
Treatment Group ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
Therapy Group ◽  
Statistical Significance ◽  
Positive Control ◽  
Control Group

ABSTRACT Objective: to evaluate the efficacy of the treatment with hyperbaric oxygen therapy or with topical and intralesional heparin in an animal model of degloving lesions. Methods: we conducted an experimental study with adult, male Wistar rats submitted to degloving of the left hind limb and divided into four groups according to the treatment: Group 1 (control) - without treatment; Group 2 (Heparin) - intralesional application at the time of surgery and topically, in the postoperative period, with heparin spray 10,000IU/mL; Group 3 (hyperbaric oxygenation) - daily sessions of 30 minutes in a hyperbaric chamber with 100% oxygen and 2 ATA pressure; Group 4 (positive control) - administration of a single dose of 45 mg/kg of intraperitoneal allopurinol. On the seventh day, we killed the animals, removed the cutaneous flaps and measured the total and necrotic areas, as well as computed the percentage of necrotic area. Results: the mean percentage of necrosis in the control group was 56.03%; in the positive control group it was 51.36% (p<0.45); in the heparin group, 42.10% (p<0.07); and in the hyperbaric oxygen therapy group, 31.58% (p<0.01) . Conclusion: both hyperbaric oxygen and heparin therapies were effective in reducing the percentage of necrosis in the model studied, although only the hyperbaric oxygenation showed statistical significance.

scholarly journals A Case of Cutaneous Leishmaniasis Treated with Hyperbaric Oxygen Therapy

2016 ◽  
Vol 57 (4) ◽  
pp. 39-41 ◽  
Author(s):  
Romuald Olszański ◽  
Piotr Siermontowski ◽  
Dariusz Juszczak ◽  
Zbigniew Dąbrowiecki ◽  
Agnieszka Pedrycz
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
Hyperbaric Chamber ◽  
Tropical Countries ◽  
Imported Disease ◽  
The Tropics

Abstract Cutaneous leishmaniasis in Poland is an imported disease mainly occurring in tourists who travelled to tropical countries. Cutaneous symptoms occur as late as between ten and twenty days following the return from the tropics. Lesions connected with cutaneous leishmaniasis were most commonly diagnosed by Polish doctors as furuncle, ecthyma or ulceration and ineffectively treated for several weeks with antibiotics. The paper presents the case of leishmaniasis in a 30-year-old male with an ulceration of the left shank, ineffectively treated with antibiotics over a period of four months. The ulceration was healed completely only after leishmaniasis was diagnosed and following the application of a treatment based on antimony derivatives, followed by hyperbaric oxygenation performed in a hyperbaric chamber.

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