scholarly journals Management of Positive Cervical Lymph Nodes in Parotid Cancer

2021 ◽  
Vol 18 (01) ◽  
Author(s):  
Zedan Ali ◽  
Morsy Aieat ◽  
Mustafa Osama ◽  
Hussien Marwa ◽  
Aboeleuien Ebrahim
Keyword(s):  
Lymph Node ◽  
Facial Nerve ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Perineural Invasion ◽  
Cervical Lymph Nodes ◽  
Duct Carcinoma ◽  
Parotid Cancer ◽  
Skin Invasion

Objective: Assessment the management of positive cervical lymph nodes in parotid cancer. Associated clinical symptoms, histological types, regional lymph node stage (n stage), occult metastasis, neck dissection by level, recurrence, neck irradiation. Methods. We carried out a retrospective analysis of 43 patient’s pathological positive lymph nodes metastatic from parodied cancer, who underwent neck dissection. treated in years 2010-2020, we analyzed the following parameters: age, sex, pT-Status, tumour size, skin invasion, facial nerve palsy, tumour fixation, extraparotid extension, localization, grade, histology, Distribution of T classification was: T3 (60%), and T4 (40%). Results: Mean patient age was 52 years, the most common location of cervical Nodes Met. was level II (72%), then III (49%) then I (42%), then IV (40%) and V (19%). The incidence was highest among patients with (27.9%) mucoepidermoid carcinoma was most common, followed by (14.6%) carcinoma ex-pleomorphic adenoma (9.3%) with acinic cell carcinoma (7%) with squamous cell carcinoma, (11.6%) with adenoid cystic carcinoma, (7.0%) with adenocarcinoma, (7.4%) salivary duct carcinoma, When classified by histological grade, 35% of patients with low/intermediate-grade versus 65.0% high-grade ., Pre-operative fine needle aspiration (83.7%) patients, Post-surgical irradiation was performed in all 43 patients (100%). The resection status (R) was Negative margins R0. (93%), lymphovascular space invasion (44.2%) and (25.6%) had perineural invasion. Skin invasion in (14%) patients, and (4.7%) had regional nodal recurrence (7%) patients with pN1, vs (93%) patients with pN2. Pathologically positive lymph node 4 (range: 1–8 Nodes) lymph nodes harvest 29(range, 23–41 lymph nodes)., Conclusion: modified Radical Neck Dissection with additional radiotherapy should be carried out in patients. Nodes positive parotied cancer especially High histological stage, advanced stage, perineural invasion, positive operative edge, a fixed mass with extra parotid extension facial-nerve paralysis and tumor pain in partied cancer.

scholarly journals Therapeutic approach of cervical lymph nodes metastases of squamous cell carcinoma from an unknown primary tumors

2015 ◽  
Vol 10 (1) ◽  
pp. 20-25
Author(s):  
Anca Ruxandra MOŞOIU ◽  
◽  
Alina Lavinia OANCEA ◽  
Roxana Mihaela MATEI ◽  
Marian STAMATE ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Unknown Primary ◽  
Cervical Lymph Nodes ◽  
Node Metastases

Cervical lymph node metastases of squamous cell carcinoma from occult primary constitute about 3-5% of all patients with carcinoma of unknown primary site (CUP). Identification of subgroups with favorable prognosis is of decisive importance for the therapy of patients with CUP syndrome, including prolonged survival from directed treatment. The patients with neck node metastases from occult head and neck cancer have clinical features and prognosis similar to other head and neck malignancies. Treatment of patients with metastatic squamous cell carcinoma involving cervical lymph nodes of an unknown primary origin should be similar to that of patients with locally advanced carcinoma of the head and neck. Therapeutic approaches include surgery (lymph node excision or neck dissection), with or without post-operative radiotherapy, radiotherapy alone and radiotherapy followed by surgery. In early stages (N1), neck dissection and radiotherapy seem to have similar efficacy, whereas more advanced cases (N2, N3) necessitate combined approaches. The extent of radiotherapy (irradiation of bilateral neck and mucosa versus ipsilateral neck radiotherapy) remains debatable. A potential benefit from extensive radiotherapy should be weighted against its acute and late morbidity and difficulties in re-irradiation in the case of subsequent primary emergence. The role of other methods, such as chemotherapy and hyperthermia, remains to be determined.

Role of Clinical Palpation in Evaluation of Cervical Lymph Node in Oral Squamous Cell Carcinoma

2013 ◽  
Vol 1 (2) ◽  
pp. 02-06
Author(s):  
SM Anwar Sadat ◽  
Sufia Nasrin Rita ◽  
Shoma Banik ◽  
Md Nazmul Hasan Khandker ◽  
Md Mahfuz Hossain ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Oral Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Predictive Value ◽  
Cervical Lymph Node ◽  
Betel Quid ◽  
Cervical Lymph Nodes

A cross sectional study of 29 cases of oral squamous cell carcinoma with or without  cervical lymph node metastasis was done among Bangladeshi patients from January 2006 to December 2007. Majority of the study subjects (34.5%) belonged to the age group of 40-49 years. 58.6% of the study subjects were male, while remaining 41.4% of them were female. 51.7% of the lesions were located in the alveolar ridge where the other common sites were buccal mucosa (27.6%) and retro molar area (13.8%). Half of the study subjects (51.7%) were habituated to betel quid chewing followed by 37.9% and 10.3% were habituated to smoking and betel quid-smoking respectively. Grade I lesions was most prevalent (75.9%) in the study subjects.  Majority of cases presented with Stage IV lesions (55.2%). The sensitivity, specificity, positive predictive value, negative predictive value & accuracy of clinical palpation method for determining metastatic cervical lymph nodes were 93.33%, 64.29%, 73.68%, 90% and 79.3% respectively. Careful and repeated clinical palpation plays important role in evaluation of cervical lymph nodes though several modern techniques may help additionally in the management of oral cancer.DOI: http://dx.doi.org/10.3329/updcj.v1i2.13978 Update Dent. Coll. j. 2011: 1(2): 02-06

scholarly journals Outcome of Cervical Lymph Nodes Dissection for Thyroid Cancer with Nodal Metastases: A Southeast Asian 3-Year Experience

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Raymond Z. M. Lim ◽  
Juin Y. Ooi ◽  
Jih H. Tan ◽  
Henry C. L. Tan ◽  
Seniyah M. Sikin
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Neck Dissection ◽  
Lymph Node Dissection ◽  
Endocrine Surgery ◽  
Node Dissection ◽  
Referral Centre ◽  
Local Data ◽  
Cervical Lymph Nodes

Introduction. Therapeutic nodal dissection is still the mainstay of treatment for patients with lymph node metastases in many centres. The local data, however, on the outcome of therapeutic LND remains limited. Hence, this study aims to inform practice by presenting the outcomes of LND for thyroid cancer patients and our experience in a tertiary referral centre.Methods. This is a single-centre retrospective observational study in a Malaysian tertiary endocrine surgery referral centre. Patients who underwent total thyroidectomy with lymph node dissection between years 2013 and 2015 were included and electronic medical records over a 3-year follow-up period were reviewed. The outcomes of different lymph node dissection (LND), including central neck dissection, lateral neck dissection, or both, were compared.Results. Of the 43 subjects included, 28 (65.1%) had Stage IV cancer. Among the 43 subjects included, 8 underwent central LND, and 15 had lateral LND while the remaining 20 had dissection of both lateral and central lymph nodes. Locoregional recurrence was found in 16 (37.2%) of our subjects included, with no statistical difference between the central (2/8), lateral (7/15), and both (7/20). Postoperative hypocalcaemia occurred in 7 (16.3%) patients, and vocal cord palsy occurred in 5 (11.6%), whereas 9 patients (20.9%) required reoperation. Death occurred in 4 of our patients.Conclusion. High recurrence and reoperative rates were observed in our centre. While the routine prophylactic LND remains controversial, high risk patients may be considered for prophylactic LND. The long-term risk and benefit of prophylactic LND with individualised patient selection in the local setting deserve further studies.

Role of Suprahyoid Neck Dissection in the Treatment of Squamous Cell Carcinoma of the Lower Lip

1997 ◽  
Vol 106 (9) ◽  
pp. 787-789 ◽  
Author(s):  
Can Koç ◽  
M. Umut Akyol ◽  
Ali Çekiç ◽  
Serdar Çelikkanat ◽  
Cafer Özdem
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Radical Neck Dissection ◽  
Occult Metastasis ◽  
Cervical Lymph Nodes ◽  
Lower Lip ◽  
Occult Metastases

Treatment of squamous cell carcinoma of the lip is primarily surgical. Unlike other oral lesions, lower lip cancers do not metastasize to lower cervical lymph nodes without invading submental and submandibular lymph nodes. This study presents 30 patients with NO lower lip carcinoma who were treated by en bloc resection of the tumor with suprahyoid neck dissection. Occult metastasis was found in 4 patients (13%). Four patients, 3 of whom had no occult metastases, died of local or regional uncontrollable disease. Suprahyoid or modified radical neck dissection appears to be beneficial, even in small tumors of the lower lip, in detecting occult metastases.

scholarly journals Staging of Cervical Lymph Nodes in Oral Squamous Cell Carcinoma: Adding Ultrasound in Clinically Lymph Node Negative Patients May Improve Diagnostic Work-Up

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e90360 ◽  
Author(s):  
Rikke Norling ◽  
Birgitte Marie Due Buron ◽  
Marianne Hamilton Therkildsen ◽  
Birthe Merete Henriksen ◽  
Christian von Buchwald ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Oral Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Cervical Lymph Nodes ◽  
Node Negative ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

scholarly journals High Resolution Sonography in Diagnosis of Metastatic Cervical Lymph Nodes in Oral Squamous Cell Carcinoma

1970 ◽  
Vol 28 (2) ◽  
pp. 92-99
Author(s):  
SM Anwar Sadat ◽  
Rufia Nasrin Rita ◽  
Asad-Uz Zaman ◽  
Md Abdur Rob ◽  
Md Musharraf Husain ◽  
...  
Keyword(s):  
Lymph Node ◽  
High Resolution ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Maxillofacial Surgery ◽  
Cost Effective ◽  
Cervical Lymph Nodes ◽  
Non Invasive ◽  
Sensitivity Specificity

Ultrasound is reported superior to clinical palpation fordetecting lymph nodes and metastasis. The advantage ofultrasound over other imaging modalities is price, lowpatient burden, and possibilities for follow up. A crosssectional Study on 29 cases of oral squamous cell carcinomawas done in Department of Oral & Maxillofacial Surgery,Dhaka Dental College & Hospital, Dhaka from January2006 to December 2007. The sensitivity, specificity, positivepredictive value, negative predictive value & Accuracy ofUltrasonographic technique for determining metastaticcervical lymph node were 93.33%, 50%, 66.7%, 87.5% and72.4% respectively. Considering the finding of the study,Sonographic evaluation can improve the diagnosis ofmetastatic cervical lymph node in patients with oralsquamous cell carcinoma. It is cost effective, non-invasive,less burden to patient, does not create problem ofoverlapping with mandible and can be done repeatedly tofollow up. Therefore, high resolution sonography may bean adjunct tool in diagnosing metastatic nodes in patientswith oral squamous cell carcinoma.DOI: 10.3329/jbcps.v28i2.5369J Bangladesh Coll Phys Surg 2010; 28: 92-99

scholarly journals Late Neck Metastasis of Clear Cell Salivary Carcinoma of the Soft Palate

2013 ◽  
Vol 5 (3) ◽  
pp. 145-147
Author(s):  
Xu Rena ◽  
Marc William Herr ◽  
Peter Sadow ◽  
Daniel Deschler
Keyword(s):  
Lymph Node ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Soft Palate ◽  
Cervical Lymph Node ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Salivary Gland Tumor ◽  
Cervical Lymph Nodes ◽  
Neck Metastasis

ABSTRACT Introduction Clear cell carcinoma is a rare form of salivary gland tumor, most commonly affecting the palate and tongue. We present a patient with cervical lymph node metastasis 28 years after treatment for clear cell salivary carcinoma of the soft palate. Case presentation A new neck mass was found in a 69-yearold man with a remote history of clear cell salivary carcinoma of the soft palate. Fine-needle aspiration biopsy demonstrated no evidence of malignancy; however, excisional biopsy revealed carcinoma. Neck dissection was performed and final pathologic review demonstrated clear cell salivary carcinoma metastatic to a cervical lymph node. Discussion Clear cell salivary carcinoma may be less indolent than previously believed. Metastases to cervical lymph nodes and distant sites have been reported in one-fourth of patients and can occur many years after treatment. Immunohistochemical staining is a valuable adjunct for differentiating clear cell carcinoma from other neoplasms that demonstrate clear cell components. Conclusion This rare case of late neck metastasis after clear cell salivary carcinoma of the soft palate highlights the need for high clinical suspicion of recurrence many years after treatment and indicates the role of neck dissection for diagnosis and treatment in patients with possible nodal spread. How to cite this article Xu R, Herr MW, Sadow P, Deschler D. Late Neck Metastasis of Clear Cell Salivary Carcinoma of the Soft Palate. Int J Otorhinolaryngol Clin 2013;5(3):145-147.

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