PERBEDAAN KADAR PM2,5 DI TEMPAT PEMBAKARAN BATU BATA DAN KEJADIAN SINDROMA MATA KERING

Brick cumbustion in Kaloran Village uses firewood and corncob as main fuel. Combustion using firewood and corncobs in burning bricks produce PM2.5 pollutants that can cause health problem including the eyes. Dry eye is a multifactorial disease of ocular surface in symptoms that include discomfort, visual disturbance and tear film instability with potential damage to the ocular surface. This study aims to describe PM2.5 levels in brick combustion and dry eye syndrome events in brick workers in Kaloran Village Ngronggot Nganjuk District in 2017. This research was an observational study with cross sectional design, conducted in May 2017, Using questionnaires, interviews and observations with a large sample of 42 respondents. The PM2.5 measurements use the Haz-Dust EPAM 5000 model for 30 minutes, which is performed three times a day at each point of location. Data collection on the incidence of dry eye syndrome was diagnosed using an OSDI questionnaire. All measurements of PM2.5 exceed the ambient air quality standard of government regulation number 41 of 1999 of (0.065 mg/m3) and There are three measurement result of PM2.5 that exceed the Threshold Limit No 13 of 2011 about Threshold Value of Physical Factors and Chemical Factors in the Work Environment. There are 71.6% workers experience dry eye syndrome. In the results of this study, PM2.5 levels are in place. The advantages and disadvantages of some places that exceed the Threshold Limit and there are workers who experience dry eye syndrome. Keywords: burning bricks, dry eye syndrome, level of PM2,5

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Dry Eye Syndrome-Related Quality of Life in Glaucoma Patients

European Journal of Ophthalmology ◽

10.1177/112067210901900409 ◽

2009 ◽

Vol 19 (4) ◽

pp. 572-579 ◽

Cited By ~ 78

Author(s):

Gemma Caterina Maria Rossi ◽

Carmine Tinelli ◽

Gian Maria Pasinetti ◽

Giovanni Milano ◽

Paolo Emilio Bianchi

Keyword(s):

Quality Of Life ◽

Dry Eye ◽

Ocular Surface ◽

Cross Sectional Study ◽

Dry Eye Syndrome ◽

Control Group ◽

Ocular Surface Disease Index ◽

Symptom Scale ◽

Cross Sectional

Purpose To verify the presence of dry eye syndrome (DES) in treated patients with glaucoma and to analyze DES's impact on the patients' quality of life (QOL) versus the control group. Methods In this observational cross-sectional study, 61 patients were enrolled at a clinical practice. Patients were divided into three groups by number of glaucoma drops instilled per day (G1=1 drop/day, G2=2 drops/day, G3=3 drops/day). A control group of 20 subjects was also selected (G0). All subjects were submitted to a complete ocular examination (including tear function and ocular surface status) and completed the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ), Glaucoma Symptom Scale (GSS) questionnaire, and Ocular Surface Disease Index (OSDI). DES was defined as presence of punctate keratitis and decreased break-up time. Statistical analysis was performed applying the Kruskal-Wallis analysis of variance and Mann-Whitney U tests (to compare median values between groups) as well as the χ2 and Fisher test (to verify significant differences). Results A total of 40% of G3 and 39% of G2 patients presented DES versus 11% of G1 and 5% of G0 (p=0.01). QOL was significantly influenced and altered (NEI-VFQ 25 total mean and GSS total mean and symptoms average: p=0.0085, p=0.006, and p=0.03, respectively). OSDI pointed out differences by group: 26% of G2 and 15% of G3 presented moderate OSDI and 15% of G3 and 8.7% of G2 severe OSDI (p>0.05). Conclusions Patients with topically treated glaucoma present DES more often than a similar control group (p=0.01). The presence of DES negatively influences the patient's QOL. The patients with glaucoma's ocular surface status should be evaluated regularly to ensure the timely detection and treatment of pathologic signs on the ocular surface.

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Pengaruh Penggunaan Obat Antihipertensi Terhadap Sindroma Mata Kering di Surabaya

Hang Tuah Medical journal ◽

10.30649/htmj.v17i2.418 ◽

2020 ◽

Vol 17 (2) ◽

pp. 159

Author(s):

WISNU TRI PAMUNGKAS ◽

INDIRA RA ◽

IRMA ANDRIANI PASARIBU

Keyword(s):

Public Health ◽

Health Center ◽

Dry Eye ◽

Channel Blocker ◽

Antihypertensive Drugs ◽

Descriptive Analysis ◽

Dry Eye Syndrome ◽

Chi Square ◽

Cross Sectional ◽

Public Health Center

AbstrakLatar Belakang : Prevalensi Hipertensi di Indonesia semakin meningkat mencapai 25,8% pada penduduk berusia 18 tahun keatas. Amlodipin merupakan salah satu pilihan obat untuk terapi Hipertensi yang termasuk golongan Calsium Channel Blocker (CCB). Penggunaan obat antihipertensi sendiri merupakan salah satu faktor risiko yang menyebabkan sindroma mata kering.Tujuan : Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan obat antihipertensi terhadap sindroma mata kering pada penderita Hipertensi di wilayah kerja Puskesmas Jagir kota Surabaya.Metode penelitian : Penelitian ini adalah penelitian observasional analitik dengan metode cross-sectional. Subyek pada penelitian ini adalah 48 responden yang didapatkan dibagi kedalam 2 kelompok yakni, kelompok minum obat antihipertensi >6 bulan dan tidak minum obat. Dilakukan pengisian kuesioner DEQ-5 dan pemeriksaan schirmer I.Hasil penelitian : Analisa deskriptif dari tes schirmer I frekuensi sindroma mata kering lebih tinggi pada responden yang mengkonsumsi obat antihipertensi dari pada responden yang tidak minum obat antihipertensi. Hasil analisa statistik menggunakan uji chi-square signifikansinya yaitu sebesar <0,001 atau dapat dikatakan bahwa p<α (0,05), menunjukkan ada pengaruh pemberian obat antihipertensi terhadap sindroma mata kering yang berdasarkan tes Schirmer pada pasien Hipertensi di wilayah kerja puskesmas Jagir kota Surabaya.Simpulan : Penggunaan obat antihipertensi berpengaruh terhadap sindroma mata kering pada penderita hipertensi di wilayah kerja Puskesmas Jagir kota SurabayaKata Kunci : Sindroma mata kering, obat antihipertensi, hipertensi AbstractBackground: Hypertension prevalence in Indonesia is increasing to reach 25.8% in the population aged 18 years and over. Amlodipine is one of the drugs for hypertension therapy which is included in the Calcium Channel Blocker (CCB) class. The use of antihypertensive medication itself is one of the risk factors that cause dry eye syndrome.Purpose: This study aims to determine the effect of the use of antihypertensive drugs on dry eye syndrome in patients with hypertension at Jagir Public Health Center in Surabaya working area.Methods: This study was an observational analytic study with a cross-sectional method. The subjects in this study were 48 respondents found divided into 2 groups namely, the group taking antihypertensive drugs> 6 months and not taking medication. The DEQ-5 questionnaire was completed and Schirmer I was examined.Results: Descriptive analysis of the Schirmer I test for the frequency of dry eye syndrome was higher in respondents who took antihypertensive drugs than those who did not take antihypertensive drugs. The results of statistical analysis using the chi-square test of significance that is equal to <0.001 or it can be said that p <α (0.05), indicates there is an effect of antihypertensive drug administration on dry eye syndrome based on the Schirmer test in hypertension patients at Jagir Public Health Center in Surabaya..Conclusion: The use of antihypertensive drugs has an effect on dry eye syndrome in patients with hypertension at the Jagir Public Health Center in SurabayaKeywords: Dry eye syndrome, antihypertensive drugs, hypertension

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A Survey on How Ocular Surface Demodex Infestation Interactively Associates with Diabetes Mellitus and Dry Eye Disease

Acta Parasitologica ◽

10.1007/s11686-021-00382-8 ◽

2021 ◽

Author(s):

Chang Huang ◽

Shuze Chen ◽

Sheng Fu ◽

Yingli Li ◽

Zhenhao Li ◽

...

Keyword(s):

Diabetes Mellitus ◽

Dry Eye ◽

Ocular Surface ◽

Cross Sectional Study ◽

General Information ◽

Potential Interaction ◽

Dry Eye Disease ◽

Eye Disease ◽

Cross Sectional ◽

Demodex Infestation

Abstract Purpose Prevention of ocular surface (OS) Demodex infestation plays an important role in OS hygiene and variety of factors may be associated with it, in which diabetes mellitus (DM) or dry eye disease (DED) has caught the attention of most scholars. However, there has been no research on whether there was a potential interaction between DM and DED in the process of OS Demodex infestation. This cross-sectional study was implemented in Zhujiang Hospital of Southern Medical University. Methods Ophthalmologic interviews, questionnaires, and examinations were conducted. Factors including general information, DM status, dry eye condition, etc. were collected to study the correlation of DM and DED on OS Demodex infestation. Results After statistical analysis, we found that both DM (P < 0.001) and DED (P = 0.013 < 0.05) are closely associated with OS Demodex infestation. Compared with DED, DM has higher priority association with OS Demodex infestation, and patients with both diseases have a significant higher risk of OS Demodex infestation (R = 0.197, P < 0.001). Meanwhile, age (R = 0.299, P < 0.001) and hypertension (P < 0.05) were also correlated with OS Demodex infestation. Conclusion This study provides a new evidence-based basis for clinical prevention and management of OS Demodex infestation.

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Dry eye disease among Glaucoma patients on topical hypotensive medications, in a tertiary hospital, Ethiopia

BMC Ophthalmology ◽

10.1186/s12886-021-01917-3 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Miraf Sahlu ◽

Abeba T. Giorgis

Keyword(s):

Dry Eye ◽

Ocular Surface ◽

Signs And Symptoms ◽

Dry Eye Disease ◽

Eye Disease ◽

Eye Drops ◽

Schirmer Test ◽

Ocular Surface Disease Index ◽

Cross Sectional ◽

Corneal Staining

Abstract Background Dry eye disease is a multifactorial disease; causing various ocular symptoms with potential damage to the ocular surface. Applying hypotensive eye drops are presumed to initiate or exacerbate existing dry eye disease. The purpose of this study was to determine the frequency of signs and symptoms and severity of dry eye disease among glaucoma patients on topical hypotensive medications and controls. Methods A cross-sectional comparative study, involving 320 glaucoma patients and controls. Ocular Surface Disease Index (OSDI) symptoms score and Schirmer, tear breakup time and corneal staining tests were used to assess dry eye disease. Data was analyzed using SPSS version 24 software; p-value less than 0.05 was considered as statistically significant. Results Among the 160 study glaucoma patients, the mean duration of topical hypotensive medication use was 5.2 ± 5.21 years (range, 4 months - 32 years). Mild to severe level of OSDI score was found in 122 (76%) glaucoma patients and in 137 (86%) controls (p = 0.033). Mild to sever abnormal clinical tests in the glaucoma patients and control, respectively, were 106 (66%) vs 80 (50%) corneal staining (p = 0.045), 79 (49%) vs 72 (45%) TBUT (p = 0.021), and 91 (57%) vs 83 (52%) Schirmer test (p = 0.242). Test results at the level of sever: 2 (1%) vs 0 (0%) corneal staining, 50 (31%) vs 39 (24%) TBUT and 65 (41%) vs 60 (38%) Schirmer test in the glaucoma patents and controls, respectively. Corneal staining and TBUT had correlation with the number of drugs (p = 0.004 and 0.031, respectively), and more relationship of the two tests with total number of drops applied per day (p = 0.01 and p < 0.001, respectively). Patients on pilocarpine and timolol had more corneal staining and lower TBUT [(p = 0.011 and p < 0.001) and (p = 0.04 and 0.012), respectively]. Conclusions The study has identified glaucoma patients to be more affected by dry eye disease than non-glaucoma patients, and presence of significantly lower TBUT and higher corneal staining in the glaucoma patients on multidrops and multidose per day. We recommend consideration of evaluation and management of DED for glaucoma patients on multidrops and multidose hypotensive medications.

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Risk Factors Influencing the Occurrence and Severity of Symptomatic Dry Eye Syndrome: A Cross-sectional Study

Ophthalmic Epidemiology ◽

10.1080/09286586.2021.1879172 ◽

2021 ◽

pp. 1-7

Author(s):

Hye Rin Choi ◽

Na Hyun Kim ◽

Ju-Mi Lee ◽

Dong Phil Choi ◽

Yuri Seo ◽

...

Keyword(s):

Risk Factors ◽

Dry Eye ◽

Cross Sectional Study ◽

Dry Eye Syndrome ◽

Sectional Study ◽

Cross Sectional ◽

Factors Influencing

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PENGARUH EMISI DEBU SEMEN TERHADAP STATUS TEAR FILM MASYARAKAT DI SEKITAR PABRIK PT. SEMEN PADANG

Jurnal Kesehatan Andalas ◽

10.25077/jka.v6i3.753 ◽

2018 ◽

Vol 6 (3) ◽

pp. 654

Author(s):

Muhammad Syauqie ◽

Ardizal Rahman ◽

Getry Sukmawati

Keyword(s):

Dry Eye ◽

Tear Film ◽

Cross Sectional Study ◽

Dry Eye Syndrome ◽

Sectional Study ◽

Cross Sectional ◽

Break Up

Permukaan okular rentan terhadap efek iritatif dari debu semen tersebut karena epitel konyungtiva dan kornea hanya dilapisi oleh lapisan tipis tear film. Paparan debu semen jangka panjang menyebabkan terjadinya inflamasi subklinis kronik yang dapat mempengaruhi transdiferensiasi epitel konyungtiva dan densitas sel goblet yang kemudian dapat menyebabkan timbulnya gejala dry eye syndrome. Tujuan penelitian ini adalah menilai status tear film pada masyarakat yang terpapar emisi debu semen dibandingkan dengan masyarakat yang tidak terpapar. Penelitian ini berupa analytic cross sectional study pada dua populasi yaitu kelompok terpapar dan tidak terpapar emisi debu pabrik semen. Semua sampel penelitian dari dua populasi menjalani pemeriksaan pH tear film, Schirmer, Ferning dan Tear Break Up Time (TBUT). Hasil studi mendapatkan peningkatan nilai pH tear film yang bermakna pada penduduk di kelompok terpapar dengan p=0.001. Terdapat juga penurunan kualitas Ferning yang bermakna pada penduduk di kelompok terpapar yang didominasi tipe III dengan p=0.005 dan 0.029. Sedangkan hasil pemeriksaan Schirmer dan TBUT masih dalam batas normal dan tidak terdapat perbedaan yang bermakna antara kedua kelompok. Simpulan studi ini ialah erdapat peningkatan rerata nilai pH tear film dan penurunan kualitas lapisan musin tear film yang bermakna pada masyarakat yang terpapar emisi debu semen namun tidak didapatkan peningkatan kejadian dry eye yang bermakna.

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Changes the Ocular Surface after Corneal Refractive Surgery. Review

Ophthalmology in Russia ◽

10.18008/1816-5095-2020-3-344-350 ◽

2020 ◽

Vol 17 (3) ◽

pp. 344-350

Author(s):

S. V. Trufanov ◽

E. V. Sukhanova ◽

A. A. Tyurina

Keyword(s):

Dry Eye ◽

Ocular Surface ◽

Refractive Surgery ◽

High Efficiency ◽

High Specificity ◽

Functional Results ◽

Dry Eye Syndrome ◽

Specificity And Sensitivity ◽

Surgery Research ◽

Corneal Refractive Surgery

Modern corneal refractive surgery provides high efficiency, safety, predictability and stability of the different ametropia kinds correction’s clinically-functional results. However, in overwhelming percentage of cases, having spent some time after surgery patients complain about discomfort, eyes dryness, burning, feel gritty, redness, blurred and vision instability. Complaints mentioned above are caused by the appearance of transitory dry eye syndrome. Main etiology and pathogenesis factors of this disease are presented in this review. The results of dry eye syndrome classical diagnosis methods have been analyzed, as well as modern techniques, characterized by high specificity and sensitivity, which allow to increase the dry eye’s diagnostics accuracy. The study of the dry syndrome after corneal refractive surgery is devoted to a huge number of works of domestic and foreign authors. However, at present time there is no unique algorithm for assessing the damage of the ocular surface before and after corneal refractive surgery, which would include a set of high-precision and specific techniques for quickly and reliably evaluate the severity of dry eye syndrome, allowing to develop preventive measures and pathogenetically oriented treatment and, thereby, accelerate rehabilitation of patients after surgery. Research continuation is needed in this direction.

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