scholarly journals Quality of Life in Patient with Systemic Lupus Erythematosus (SLE)

2016 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Irma Yanih
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Body Image ◽  
Physical Health ◽  
Lupus Erythematosus ◽  
Emotional Health ◽  
Intimate Relationship ◽  
Nutrition Status ◽  
Systemic Lupus

The number of patient with Systemic Lupus Erythematosus (SLE) was keep growing. SLE attacked many women and developed between the age of 15-45. The treatment which used by patient with SLE just for reduced or faded the symptoms that occurred. It couldn’t heals the patient properly yet, so that sometimes that symptoms would occur again. The object of this study were to see the quality of life from 13 patient SLE in 8 domain from Quality of Life (QoL) such as physical health, emotional health, body image, pain, planning, fatigue intimate relationship and burden to others. This study was a study case in 13 patient with SLE which lived in Surabaya and a member of Lupus Indonesia Foundation branch Surabaya. Primary data were collected by interview using LupusQoL questionnaire and the weight was measured by digital weight scales. In this study, there were 13 woman patient with SLE in the age between 15–40 years old with highly educated and having normal nutrition status. They usually work and having monthly income > Rp 1,740,000, were suffer SLE for more than 5 years and having good knowledge in Lupus and SLE. This study showed a good value quality of life in patient with SLE at 3 domain. That were body image, intimate relationship and physical health domain. Some patients had a bad even worse quality in pain, fatigue and burden to others domain. Some of patients with SLE had a good quality of life except pain, fatigue, and burden to others domain. Keywords: Quality of Life (QoL), Systemic Lupus Erythematosus (SLE), desease duration

scholarly journals Depression and Quality of Life in People with Systemic Lupus Erythematosus

2018 ◽  
Vol 33 (3) ◽  
Author(s):  
Fitria Maharani Harsono Putri ◽  
Magdalena S. Halim
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Body Image ◽  
Lupus Erythematosus ◽  
Additional Data ◽  
Demographic Factors ◽  
Systemic Lupus ◽  
Significant Difference ◽  
The Relationship

The aim of this research was to determine the relationship between depression and some aspects of the quality of life. As additional data, the researchers sought connections between demographic factors and the quality of life. This research used measurement implements in the form of the Beck Depression Inventory-II (BDI-II) and the LupusQoL. The participants involved in the research were 49 females aged between 18 and 45 years. The results of the research indicated that depression has a significant relationship with all aspects of quality of life, with the exception of the aspect of body image. The greater the depression, the worse the quality of life. Conversely, the lighter the depression, the better the quality of life. Besides this, the research also indicated a significant difference in aspects of the quality of life, on the basis of demographic factors. The conclusion from the research is that depression is an important matter for attention. By overcoming depression, a number of aspects of the quality of life of people with Lupus/SLE may be improved.

Body image mediates the impact of pain on depressive symptoms in patients with systemic lupus erythematosus

Lupus ◽  
2019 ◽  
Vol 28 (9) ◽  
pp. 1148-1153
Author(s):  
S Gholizadeh ◽  
D R Azizoddin ◽  
S D Mills ◽  
G Zamora ◽  
H M K Potemra ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Body Image ◽  
Depressive Symptoms ◽  
Lupus Erythematosus ◽  
Urban Region ◽  
Systemic Lupus ◽  
Related Quality ◽  
The Relationship

Objective Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with treatment manifestations that can cause changes in appearance, including skin rashes, alopecia, vitiligo, and scars. SLE has been shown to adversely impact body image outcomes, and previous research has identified that greater disease activity is associated with worse body image outcomes which, in turn, are associated with greater depressive symptoms. For patients with SLE who also experience significant pain, poor body image outcomes may further compromise wellbeing and lead to greater depressive symptoms. The role of pain in body image has not been explored in SLE. Thus, the present study examined whether body image (specifically, body image-related quality of life) serves as a mediator of the relationship between pain and depressive symptoms among patients with SLE. Methods Multiple mediation analysis was used to examine the hypothesis that body image-related quality of life mediates the relationship between pain and depressive symptoms in a sample of patients with SLE ( N = 135) from an urban region in Los Angeles, California. Results The sample was predominately female (92.6%) with a mean disease duration of approximately 17 years. Approximately one-quarter of the sample had elevated depressive symptoms. Body image-related quality of life was a significant mediator in the relationship between pain and depressive symptoms. The model accounted for 51% of the total variance in depressive symptoms ( R2 = 0.51). Conclusion This cross-sectional study suggested that body image-related quality of life may mediate the effects of pain on depressive symptoms among patients with SLE.

scholarly journals Impact of demographic, clinical, and treatment compliance characteristics on quality of life of Venezuelan patients with systemic lupus erythematosus

2022 ◽  
Vol 6 (1) ◽  
Author(s):  
Fhabián S. Carrión-Nessi ◽  
María V. Marcano-Rojas ◽  
Sinibaldo R. Romero Arocha ◽  
Daniela L. Mendoza Millán ◽  
David A. Forero-Peña ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Risk Factor ◽  
Physical Health ◽  
Lupus Erythematosus ◽  
Intimate Relationships ◽  
Treatment Compliance ◽  
Systemic Lupus ◽  
Physical Health Domain

Abstract Background We have here assessed the impact of demographic, clinical, and treatment compliance characteristics on health-related quality of life (HRQoL) of Venezuelan patients with systemic lupus erythematosus (SLE). We have used a disease-specific questionnaire, the Lupus Quality of Life (LupusQoL), validated in our patient population, to measure HRQoL. Methods A cross-sectional study was conducted among 100 patients with SLE from outpatient clinics. Patients completed a form with demographic, clinical, and treatment compliance data, and the LupusQoL questionnaire. HRQoL was classified as better or worse according to previously established cut-off points for this patient population. Spearman’s r test was used to determine the correlations between age, years of education, disease duration, SLEDAI, and SLICC-DI with the eight domains of the LupusQoL. Mann–Whitney U test was used to compare the HRQoL between the two groups of patients according to treatment compliance. Binomial logistic regression using the backward stepwise selection method was performed to identify the risk factors associated with each of the eight domains of the LupusQoL among patients with inactive (SLEDAI < 4) and active (SLEDAI ≥ 4) SLE. Results HRQoL of our patients was classified as better in all domains of the LupusQoL. Age correlated negatively with all domains of the LupusQoL, except with “burden to others”, and disease activity correlated negatively with all domains of the LupusQoL, except with “intimate relationships” and “burden to others” (p < 0.05). Patients who fully complied with indicated treatment had higher scores in “physical health” domain compared to patients who did not comply with at least one of the prescribed medications (p < 0.05). In patients with active SLE, a risk factor associated with worse “planning” and “intimate relationships” was advanced age, while having had SLE flare-ups in the previous six months was a risk factor associated with worse “physical health” (p < 0.05). Conclusion Age and disease activity were negatively correlated with almost all domains of the LupusQoL, and treatment compliance was associated with higher score in the “physical health” domain. Disease control and treatment compliance should be the main goals for a better HRQoL in our patients with SLE.

scholarly journals Linguistic Validation of the LupusQoL for the Assessment of Quality of Life in Iranian Patients with Systemic Lupus Erythematosus

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Naeimehossadat Hosseini ◽  
Zahra Sayed Bonakdar ◽  
Ali Gholamrezaei ◽  
Leila Mirbagher
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Psychometric Properties ◽  
Lupus Erythematosus ◽  
Emotional Health ◽  
Inactive Disease ◽  
Systemic Lupus ◽  
Sf 36 ◽  
Disease Damage

Objectives.We evaluated the psychometric properties of the Persian LupusQoL for the evaluation of quality of life in Iranian systemic lupus erythematosus (SLE) patients.Methods.The LupusQoL was translated to Persian language. Patients with SLE (n=78) completed the LupusQoL and the Short-Form Health Survey (SF-36). Disease activity and cumulative disease damage were assessed with standard indices. The psychometric properties of the scale were evaluated.Results.The Cronbach’s alpha was 0.97 for the total LupusQoL (above 0.8 for subscales). There were strong corrected item-total (r>0.4), item-subscale (r≥0.5), and subscale-total correlations (r>0.6), as well as intersubscale correlations (r>0.5). Patients with active disease and patients with disease damage index of ≥1 had lower scores in domains of planning, emotional health, burden to others, and body image than patients with inactive disease and those with no disease damage, respectively (P<0.05). The LupusQoL and the SF-36 correlated well regarding comparable domains (r>0.4).Conclusion.The psychometric characteristics of the Persian version of LupusQoL questionnaire are acceptable in Iranian population. This instrument can be used to evaluate quality of life in Iranian SLE patients.

scholarly journals Impact of Demographic, Clinical, and Treatment Compliance Characteristics on Quality of Life of Venezuelan Patients With Systemic Lupus Erythematosus

2021 ◽  
Author(s):  
Fhabián S. Carrión-Nessi ◽  
María V. Marcano-Rojas ◽  
Sinibaldo R. Romero Arocha ◽  
Daniela L. Mendoza Millán ◽  
David A. Forero-Peña ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Risk Factor ◽  
Physical Health ◽  
Lupus Erythematosus ◽  
Intimate Relationships ◽  
Treatment Compliance ◽  
Systemic Lupus ◽  
Physical Health Domain

Abstract BackgroundWe have here assessed the impact of demographic, clinical, and treatment compliance characteristics on health-related quality of life (HRQoL) of Venezuelan patients with systemic lupus erythematosus (SLE). We have used a disease-specific questionnaire, the Lupus Quality of Life (LupusQoL), validated in our patient population, to measure HRQoL.MethodsA cross-sectional study was conducted among 100 patients with SLE from outpatient clinic. Patients completed a form with demographic, clinical, and treatment compliance data, and the LupusQoL questionnaire. HRQoL was classified as better or worse according to the cutoff points previously established for this patient population. Spearman’s r test was used to determine the correlations between age, years of education, disease duration, SLEDAI, and SLICC-DI with the eight domains of the LupusQoL. Mann–Whitney U test was used to compare HRQoL between the two groups of patients according to treatment compliance. Binomial logistic regression using the backward successive step selection method was performed to identified the risk factors associated with each of the eight domains of the LupusQoL between patients with inactive SLE (SLEDAI < 4) and active (SLEDAI ≥ 4).ResultsHRQoL of our patients was classified as better in all domains of the LupusQoL. Age correlated negatively with all domains of the LupusQoL, except with “burden to others”, and disease activity correlated negatively with all domains of the LupusQoL, except with “intimate relationships” and “burden to others” (p < 0.05). Patients who fully complied with indicated treatment had higher scores in “physical health” domain compared to patients who did not comply with at least one of the prescribed medications (p < 0.05). In patients with active SLE, a risk factor associated with worse “planning” and “intimate relationships” was older age, while having had SLE flare-ups in the previous six months was a risk factor associated with worse “physical health” (p < 0.05).ConclusionAge and disease activity were negatively correlated with almost all domains of the LupusQoL, and treatment compliance was associated with higher score in the “physical health” domain. Disease control and treatment compliance should be the main goals for a better HRQoL in our patients with SLE.

Assessment of Quality of Life (QoL) in Systemic Lupus Erythematosus Patients at a Tertiary Care Hospital in Egypt

2019 ◽  
Vol 15 (4) ◽  
pp. 304-311
Author(s):  
Mervat E. Behiry ◽  
Sahar A. Ahmed ◽  
Eman H. Elsebaie
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Tertiary Care ◽  
Damage Index ◽  
Life Questionnaire ◽  
Care Hospital ◽  
Systemic Lupus

: Systemic Lupus Erythematosus (SLE) has a profound impact on quality of life. Objective: The objective of this study was to explore the quality of life among Egyptian SLE patients and to assess its relationships with demographic and clinical features. Methods: One hundred sixty-four SLE patients were recruited for this study. Demographic information; clinical parameters; disease activity, as evaluated by the systemic lupus erythematosus Disease Activity Index; and organ damage, as assessed by the systemic lupus international Collaborative Clinics/American College of Rheumatology Damage Index, were reported. Quality of life was assessed with a quality of life questionnaire specifically designed for patients with systemic lupus erythematosus; the questions are grouped in the following six domains: physical function, sociooccupational activities, symptoms, treatment, mood, and self-image. Higher values indicate poorer quality of life. Conclusion: Poor quality of life among Egyptian SLE patients and disease activity are strongly related to impaired lifestyles in these patients.

scholarly journals Impact of depression on quality of life in systemic lupus erythematosus patients

2021 ◽  
Vol 57 (1) ◽  
Author(s):  
Eman M. Khedr ◽  
Rania M. Gamal ◽  
Sounia M. Rashad ◽  
Mary Yacoub ◽  
Gellan K. Ahmed
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Short Form ◽  
Systemic Lupus ◽  
Positive Correlation ◽  
Depressed Patients ◽  
Sf 36 ◽  
The Impact

Abstract Background Depression is common in systemic lupus erythematosus (SLE) and is an unmeasured risk factor, yet its symptoms can be neglected in standard disease evaluations. The purpose of this study was to assess the frequency and the impact of depression on quality of life in SLE patients. We recruited 32 patients with SLE and 15 healthy control volunteers in the study. The following investigations were undertaken in each patient: clinical and rheumatologic assessment, SLE Disease Activity Index-2k (SLEDAI-2k), Beck Depression Inventory (BDI), Short-Form Health Survey (SF-36) questionnaire, and routine laboratory tests. Results There was a high percentage of depression (46.9%) in the SLE patients. Regarding quality of life (SF-36), there were significant affection of the physical and mental composite summary domains (PCS and MCS) scores in lupus patients compared with controls (P < 0.000 for both) with the same significant in depressed compared with non-depressed patients. SF-36 subscales (physical function, limit emotional, emotional wellbeing, and social function) were significantly affected in depressed lupus patients compared with non-depressed patients. There was a significant negative correlation between the score of MCS domain of SF-36 with BDI (P < 0.000) while positive correlation between SLEDAI score with depression score. In contrast, there were no significant correlations between MCS or PCS with age, duration of illness, or SLEDAI-2K. Conclusions Depression is common in SLE patients and had a negative impact on quality of life particularly on MCS domain and positive correlation with disease severity score. Trial registration This study was registered on clinical trial with registration number: NCT03165682 https://clinicaltrials.gov/ct2/show/NCT03165682 on 24 May 2017.

scholarly journals A Comparison of the Correlation of Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) and Systemic Lupus Erythematosus Disease Activity Score (SLE-DAS) with Health-Related Quality of Life

2021 ◽  
Vol 10 (10) ◽  
pp. 2137
Author(s):  
Ning-Sheng Lai ◽  
Ming-Chi Lu ◽  
Hsiu-Hua Chang ◽  
Hui-Chin Lo ◽  
Chia-Wen Hsu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Activity Index ◽  
Disease Activity Index ◽  
Information Criterion ◽  
Systemic Lupus Erythematosus Disease ◽  
Systemic Lupus

Background and Aim: The aim of this study was to compare the correlation of a recently developed systemic lupus erythematosus disease activity score (SLE-DAS) with the SLE disease activity index 2000 (SLEDAI-2K) with the Lupus Quality of Life questionnaire (LupusQoL) in Taiwanese patients with SLE. Methods: A cross-sectional study was conducted in a regional teaching hospital in Taiwan from April to August 2019. Adult patients with a clinician-confirmed diagnosis of SLE based on the 1997 American College of Rheumatology revised criteria or the 2012 Systemic Lupus International Collaborating Clinics Classification Criteria were recruited. SLE disease activity was measured with both SLEDAI-2K and SLE-DAS. Disease-specific quality of life was assessed using the LupusQoL. Results: Of the 333 patients with SLE in this study, 90.4% were female and 40% were between the ages of 20 and 39 years. The median SLEDAI-2K score was 4.00 (interquartile range [IQR] 2.00–7.50) and the median SLE-DAS score was 2.08 (IQR 1.12–8.24) in our patients with SLE. After adjusting for sex and age intervals, both SLEDAI-2k and SLE-DAS were significantly and inversely associated with all eight domains of LupusQoL. The magnitudes of the mean absolute error, root mean square error, Akaike Information Criterion, Bayesian Information Criterion, and coefficient of determination were comparable between SLEDAI-2K and SLE-DAS. Conclusions: There were no clear differences in the use of SLE-DAS over SLEDAI-2K in assessing HRQoL in patients with SLE. We suggest that, in this aspect, both SLEDAI-2K and SLE-DAS are effective tools for measuring disease activity in patients with SLE.

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