scholarly journals Innovative Multi-Site Photoplethysmography Analysis for Quantifying Pulse Amplitude and Timing Variability Characteristics in Peripheral Arterial Disease

Author(s):  
Michael Bentham ◽  
Gerard Stansby ◽  
John Allen

Photoplethysmography (PPG) is a simple-to-perform vascular optics measurement technique that can detect changes in blood volume in the microvascular tissue bed. Beat-to-beat analysis of the PPG waveform enables the study of the variability of pulse features such as amplitude and pulse arrival time (PAT), and when quantified in the time and frequency domains, has considerable potential to shed light on perfusion changes associated with peripheral arterial disease (PAD). In this pilot study innovative multi-site bilateral finger and toe PPG recordings from 43 healthy control subjects and 31 PAD subjects were compared (recordings each at least 5 minutes, collected in a warm temperature-controlled room). Beat-to-beat normalized amplitude and PAT variability was then quantified in the time-domain using SD and IQR measures and in the frequency-domain bilaterally using Magnitude Squared Coherence (MSC). Significantly reduced normalized amplitude variability (healthy control 0.0384 (IQR 0.0217-0.0744) vs PAD 0.0160 (0.0080-0.0338) (p<0.001) and significantly increased PAT variability (healthy control 0.0063 (0.0052-0.0086) vs PAD 0.0093 (0.0078-0.0144) (p<0.001) was demonstrated in PAD using the time-domain analysis. Frequency-domain analysis demonstrated significantly lower MSC values across a range of frequency bands for PAD patients. These changes suggest a loss of right-to-left body side coherence and cardiovascular control in PAD. This study has also demonstrated the feasibility of using these measurement and analysis methods in studies investigating multi-site PPG variability for a wide range of cardiac and vascular patient groups.

Diseases ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 81 ◽  
Author(s):  
Michael Bentham ◽  
Gerard Stansby ◽  
John Allen

Photoplethysmography (PPG) is a simple-to-perform vascular optics measurement technique that can detect blood volume changes in the microvascular bed of tissue. Beat-to-beat analysis of the PPG waveform enables the study of the variability of pulse features, such as the amplitude and the pulse arrival time (PAT), and when quantified in the time and frequency domains, has considerable potential to shed light on perfusion changes associated with peripheral arterial disease (PAD). In this pilot study, innovative multi-site bilateral finger and toe PPG recordings from 43 healthy control subjects and 31 PAD subjects were compared (recordings each at least five minutes, collected in a warm temperature-controlled room). Beat-to-beat normalized amplitude variability and PAT variability were then quantified in the time-domain using two simple statistical measures and in the frequency-domain bilaterally using magnitude squared coherence (MSC). Significantly reduced normalized amplitude variability (healthy control 0.0384 (interquartile range 0.0217–0.0744) vs. PAD 0.0160 (0.0080–0.0338) (p < 0.0001)) and significantly increased PAT variability (healthy control 0.0063 (0.0052–0.0086) vs. PAD 0.0093 (0.0078–0.0144) (p < 0.0001)) was demonstrated for the toe site in PAD using the time-domain analysis. Frequency-domain analysis demonstrated significantly lower MSC values across a range of frequency bands for PAD patients. These changes suggest a loss of right-to-left body side coherence and cardiovascular control in PAD. This study has also demonstrated the feasibility of using these measurement and analysis methods in studies investigating multi-site PPG variability for a wide range of cardiac and vascular patient groups.


1994 ◽  
Vol 116 (4) ◽  
pp. 781-786 ◽  
Author(s):  
C. J. Goh

The convergence of learning control is traditionally analyzed in the time domain. This is because a finite planning horizon is often assumed and the analysis in time domain can be extended to time-varying and nonlinear systems. For linear time-invariant (LTI) systems with infinite planning horizon, however, we show that simple frequency domain techniques can be used to quickly derive several interesting results not amenable to time-domain analysis, such as predicting the rate of convergence or the design of optimum learning control law. We explain a paradox arising from applying the finite time convergence criterion to the infinite time learning control problem, and propose the use of current error feedback for controlling possibly unstable systems.


Author(s):  
Bonjun Koo ◽  
Jang Whan Kim

The Extendable Draft Platform (EDP) is a deep draft, column stabilized platform with a deck box support for topsides and a single, deep draft heave plate that provides suitable motion characteristics to enable the use of dry tree top tensioned risers. The EDP can be fabricated with topsides installed on the deck box and commissioned quayside in a typical construction yard. With the columns in the retracted position, the EDP floats on its deck box and can be towed, in this configuration, to the location of interest. Once the EDP is transported to its final site, the columns and heave plate are lowered to their final operating draft. During the lowering sequence, the deck box and the lower hull become two relatively independent bodies, mechanically connected by chains that control the lowering of the columns and heave plate, and the guides between the deck box and the columns. This multi-body system is hydrodynamically coupled because of radiated and diffracted waves. The global performance analyses of the installation process (lowering of the lower hull) are carried out by three different methods. The first method is frequency-domain analysis by WAMIT and a frequency domain motion solver. In the frequency domain analysis, all the mechanical connections are modeled as linear springs. The second method is time-domain, partially coupled analysis using HARP/WINPOST. In this analysis, the off diagonal 6×6 hydrodynamic interactions are ignored. The last method is a time domain, fully coupled analysis using HARP/WINPOST. In this analysis, full 12×12 hydrodynamic interactions are considered. In the time domain analyses, the mechanical couplings between each column and deck box are modeled with linear springs and the chain connections are modeled with slender rods by using the nonlinear finite element method. This paper presents and compares analysis results based on the three methods for relative motions and loads between the deck box and the lower hull during the lowering of the columns and heave plate.


2015 ◽  
Vol 31 (5) ◽  
pp. 292-308 ◽  
Author(s):  
Jianhua Wu ◽  
Toyin Ajisafe ◽  
Matthew Beerse

This study used both time and frequency domain analyses to investigate walking patterns with ankle load in children and adults. Twenty-two children aged 7–10 years and 20 young adults participated in this study. Three levels of ankle load were manipulated: no load, low load (2% of body mass on each side), and high load (4% of body mass on each side). An instrumented treadmill was used to register vertical ground reaction force (GRF) and spatiotemporal parameters, and peak vertical GRFs were determined. A frequency domain analysis was conducted on the vertical GRF data. Results demonstrate that, in the time domain, children showed adult-like spatiotemporal parameters and adult-like timing and magnitude of the 2 peak vertical GRFs under each load. In the frequency domain, children produced a lower power from the second harmonic than young adults, although both groups showed the highest power from this harmonic and increased this power with ankle load. It was concluded that children aged 7–10 years may start showing adult-like neuromuscular adaptations to increasing ankle load and display similar spatiotemporal control of foot falls and foot–floor kinetic interaction; however, a frequency domain analysis is effective in revealing different kinetic and neuromuscular characteristics between children and adults.


2020 ◽  
Vol 12 (09) ◽  
pp. 2050103
Author(s):  
Alvin Maningding ◽  
Mojtaba Azadi

The force response of poroelastic materials including poroelastic gels to indentation is known to be time- and space-dependent (i.e., a function of indenter shape and size). Despite the complexity of the poroelastic response and in contrast to viscoelastic mechanics, poroelastic mechanics can be captured in terms of several intrinsic mechanical properties, such as elasticity, permeability, and Poisson ratio. While these intrinsic properties can be found from time-domain or frequency-domain master curves, indentation is usually conducted and analyzed only in the time domain using stress-relaxation or creep experiments. This paper advocates using frequency-domain analysis of poroelastic gels by reviewing and analyzing the relevant works of the literature. The analysis and methods, proposed here, enable researchers to characterize dynamic moduli of poroelastic gels in frequency domain using only a few experimental defining parameters. The authors have intentionally provided extensive details and background, to make this work useful for researchers who consider using frequency-domain analysis for the first time. This work reviews and explains the instantaneous elastic modulus, depicted over normalized time as a unifying and understandable set of master curves for time-domain stress relaxation tests on poroelastic gels for cylindrical, conical, and spherical indenters. The dynamic elastic modulus, depicted over normalized frequency, are derived symbolically and numerically and explained for the first time as master curves with simple transfer function in the frequency domain for presenting poroelastic mechanics of gels.


Author(s):  
Arcandra Tahar ◽  
John Halkyard ◽  
Mehernosh Irani

The Horn Mountain Spar is located in 1,654 m of water about 135 km from Venice, Louisiana in the Gulf of Mexico. The facility was instrumented extensively to measure key spar and riser response parameters (Edwards et. al. 2003). Halkyard et. al. (2004) and Tahar et. al. (2005) have compared measured spar responses such as motion and mooring line tensions with numerical predictions. This paper extends the work done on comparison of the full scale data during hurricane Isidore. All previous numerical simulations were based on a time domain analysis procedure. One concern related to this method is that it is computationally intensive and time consuming. In the initial stages of a project, a frequency domain solution may be an effective tool compared with a fully coupled time domain analysis. The present paper compares results of time domain and frequency domain simulations with field measurements. Particular attention has been placed on the importance of the phase relationship between motion and excitation force. In the time domain analysis, nonlinear drag forces are applied at the instantaneous position. Whereas in the frequency domain analysis, nonlinear drag forces are stochastically linearized and solutions are obtained by an iterative procedure. The time domain analysis has better agreement with the field data compared to the frequency domain. Overall, however, the frequency domain method is still promising for a quick and approximate estimation of relevant statistics. With advantages in terms of CPU time, the frequency domain method can be recommended as a tool in pre-front end engineering design or in a phase where an iterative nature of design of an offshore structure takes place.


Author(s):  
Ying Min Low ◽  
Robin S. Langley

This paper outlines the dynamic analysis of flexible risers in the time and frequency domain using lumped mass discretization, where tension and bending are modeled with extensional and rotational springs respectively. For the time domain analysis, integration is carried out using the Wilson-theta implicit scheme, which allows the use of relatively large time steps without compromising stability. This increases computational efficiency and automatically filters the high frequency axial responses. The time domain code is validated with the commercial software Orcaflex, which employs an explicit scheme, and results are found to match for the same number of elements. The relative merits of implicit and explicit integration schemes are discussed. For the frequency domain analysis, the added mass, damping, axial/bending stiffness matrices are formulated in global coordinates. The nonlinear drag force is linearized iteratively for both regular and random waves. The range of accuracy for the linearized frequency domain simulations is assessed by methodical comparisons with the nonlinear time domain results for varying loading amplitudes. One problem encountered during the early development of an analytical tool is the lack of published results for validation, especially where access to commercial packages and test facilities is unavailable or limited. Hence, the simulation results presented herein are for a flexible hanging riser with simple boundary conditions and load cases to facilitate benchmarking.


Author(s):  
Chan K. Yang ◽  
D. H. Lee ◽  
M. H. Kim ◽  
B. N. Park ◽  
Y. T. Yang ◽  
...  

In this paper, the float-off operation of a land-built crude oil tank (COT) loaded out and towed on launching dual-submersible barges is numerically simulated by a time-domain vessel-mooring-riser coupled dynamic analysis program with multiple floating bodies. The study is particularly focused on the maximum load prediction on connectors and the minimum gap prediction between barges and the COT. In case of simpler modeling, the time-domain simulation results are compared with frequency-domain results. Then, the time-domain model is run for more realistic situation with hawsers and mooring line. In hydrodynamic analysis, the interactions among the 3 floating bodies are fully taken into consideration. In the frequency-domain analysis, the connectors between barges are modeled by equivalent translational and rotational springs, the stiffness of which is estimated using Euler’s beam theory. In order to assess the possible occurrence of contact between COT and barges, the relative motions between barges and the COT at several points of interest were investigated.


Electronics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 1504 ◽  
Author(s):  
Stefano Gaiotto ◽  
Antonino Laudani ◽  
Gabriele Maria Lozito ◽  
Francesco Riganti Fulginei

In this paper, a novel algorithm with high computational efficiency is proposed for the filter adaptation in a feedforward active noise control system. The proposed algorithm Zero Forcing Block Adaptive Filter (ZF-BAF) performs filter adaptation on a block-by-block basis in the frequency domain. Filtering is performed in the time domain on a sample-by-sample basis. Working in the frequency domain permits us to get sub-linear complexity, whereas filtering in the time domain minimizes the latency. Furthermore, computational burden is tunable to meet specific requirements about adaptation speed and processing load. No other parameter tuning according to the working condition is required. Computer simulations, performed in different realistic cases against other high-performing time and frequency-domain algorithms, show that achievable performances are comparable, or even better, with those of the algorithms perfectly tuned for each specific case. Robustness exhibited in the tests suggests that performances are expected to be even better in a wide range of real cases where it is impossible to know a priori how to tune the algorithms.


Author(s):  
Safia Abdullah Al Fadhel, Amal Al-Ser Al-khadir, Obeid Mahmo

:   This paper takes into account the application of the Periodogram and the Fourier Series Analysis. It is one of the non-parametric methods of Frequency domain analysis or spectral analysis of time series using Gas sales data in the United States of America from 1993-2014. In order to achieve these objectives، the data were obtained and then the Periodogram and the Fourier series methods were used to analyze the data. Based on the analysis، the cycle of variability within the period under study was 135 months، and a high Accuracy data model was estimated for the Fourier series which included trend، seasonal and error components. The RMSE، MASE and MAE standards were used to confirm the efficiency of the model and the model was then used to predict gas sales for six months، and we have 90% 95% confidence intervals for predictions. In addition، a time domain analysis was provided for the data series using Bok Jenkins method to obtain the appropriate ARMA model and to generate Predictions. Finally، a comparison was made between the accuracy measures of the time domain and frequency domain methods The frequency domain method competed with the time domain and the slight difference in efficiency.


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