scholarly journals Effect of Spirulina maxima Supplementation and a Systematic Physical Exercise Program on Body Composition and Cardiorespiratory Fitness of Overweight or Obese Subjects: A Double Blind Randomized, Crossover Controlled Trial

2018 ◽  
Author(s):  
Marco Antonio Hernández-Lepe ◽  
José Alberto López-Díaz ◽  
Marco Antonio Juárez-Oropeza ◽  
Rosa Patricia Hernández-Torres ◽  
Abraham Wall-Medrano ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Physical Exercise ◽  
Cardiorespiratory Fitness ◽  
Controlled Trial ◽  
Exercise Program ◽  
Spirulina Maxima ◽  
Double Blind ◽  
Fitness Parameters ◽  
Obese Subjects

: Background: Overweight and obesity are major risk factors for many chronic diseases, and weight-loss interventions often include systematic exercising and nutritional supplements. The purpose of this study was to determine the independent/synergistic effects of Spirulina maxima supplementation (6-week, 4.5 g/day) and a systematic physical exercise program (6 weeks/ 2 times) on body composition and cardiorespiratory fitness of overweight and obese subjects. Methods: 27 overweight and 25 obese sedentary male subjects were assigned to four interventions through a randomized double-blind, crossover controlled trial: Physical exercise program with (SE) or without (Ex) Spirulina maxima or no-exercise program with (Sm) and without (C) Spirulina maxima. Body composition and cardiorespiratory fitness parameters were taken during a maximal intensity test. Results: As compared to C group, SE, Sm and Ex groups reduced (p < 0.05) their body fat percentage while improving their maximal oxygen uptake (VO2max; r = −0.40), being obese subjects more benefited. Weight loss, time to reach fatigue and onset of blood lactate accumulation were improved in both Spirulina maxima supplemented groups, regardless the subjects’ body composition. Conclusions: Spirulina maxima supplementation synergistically improves the effects of systematic exercise in body composition and cardiorespiratory fitness parameters in overweight but mostly in obese adults.

scholarly journals Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program on the Body Composition and Cardiorespiratory Fitness of Overweight or Obese Subjects: A Double-Blind, Randomized, and Crossover Controlled Trial

Marine Drugs ◽  
2018 ◽  
Vol 16 (10) ◽  
pp. 364 ◽  
Author(s):  
Marco Hernández-Lepe ◽  
José López-Díaz ◽  
Marco Juárez-Oropeza ◽  
Rosa Hernández-Torres ◽  
Abraham Wall-Medrano ◽  
...  
Keyword(s):  
Body Composition ◽  
Physical Exercise ◽  
Cardiorespiratory Fitness ◽  
Controlled Trial ◽  
Exercise Program ◽  
The Body ◽  
Spirulina Maxima ◽  
Double Blind ◽  
Fitness Parameters ◽  
Obese Subjects

Excess weight and obesity are major risk factors for many chronic diseases, and weight-loss interventions often include systematic exercise and nutritional supplements. The purpose of this study was to determine the independent/synergistic effects of Arthrospira (Spirulina) maxima supplementation (six weeks, 4.5 g·day−1) and a systematic physical exercise program (six weeks, twice weekly) on the body composition and cardiorespiratory fitness of overweight and obese subjects. To achieve this, 27 overweight and 25 obese sedentary male subjects were assigned to four interventions through a randomized double-blind, crossover controlled trial: A physical exercise program, with (SE) or without (Ex) Spirulina maxima; or no-exercise program, with (Sm) and without (C) Spirulina maxima. The body composition and cardiorespiratory fitness parameters were taken during a maximum intensity test. As compared to the C group, the body fat percentage of the SE, Sm and Ex groups was reduced (p < 0.05), while their maximal oxygen uptake improved (r = −0.40), and obese subjects benefited more significantly. Weight loss, the time to reach fatigue and the onset of blood lactate accumulation were improved in both of the Spirulina maxima supplemented groups, regardless of the subjects’ body weight. Spirulina maxima supplementation synergistically improves the effects of systematic exercise on body composition and cardiorespiratory fitness parameters in overweight, but mostly in individuals with obesity. Trial registration: Clinical Trials, NCT02837666. Registered 19 July 2016.

scholarly journals Hypolipidemic Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program in Overweight and Obese Men: A Double-Blind, Randomized, and Crossover Controlled Trial

Marine Drugs ◽  
2019 ◽  
Vol 17 (5) ◽  
pp. 270 ◽  
Author(s):  
Marco Antonio Hernández-Lepe ◽  
Abraham Wall-Medrano ◽  
José Alberto López-Díaz ◽  
Marco Antonio Juárez-Oropeza ◽  
Oscar Iván Luqueño-Bocardo ◽  
...  
Keyword(s):  
Body Weight ◽  
Physical Exercise ◽  
Plasma Lipids ◽  
Controlled Trial ◽  
Exercise Program ◽  
Density Lipoprotein ◽  
Excess Body Weight ◽  
Hypolipidemic Effect ◽  
Spirulina Maxima ◽  
Double Blind

Low-fat diets, lipid-modifying nutraceuticals and a higher level of physical activity are often recommended to reduce dyslipidemia. A double-blind, randomized, crossover, controlled trial was designed to evaluate the independent and synergistic effects of Arthrospira (Spirulina) maxima supplementation (4.5 g·day−1) with or without performing a physical exercise program (PEP: aerobic exercise (3 days·week−1) + high-intensity interval training (2 days·week−1)) on blood lipids and BMI of 52 sedentary men with excess body weight. During six weeks, all participants were assigned to four intervention treatments (Spirulina maxima with PEP (SE), placebo with PEP (Ex), Spirulina maxima without PEP (Sm), placebo without PEP (C; control)) and plasma lipids were evaluated spectrophotometrically pre- vs. post intervention in stratified subgroups (overweight, obese and dyslipidemic subjects). Pre/post comparisons showed significant reductions in all plasma lipids in the SE group, particularly in those with dyslipidemia (p ≤ 0.043). Comparing the final vs. the initial values, BMI, total cholesterol, triglycerides and low-density lipoprotein cholesterol were decreased. High-density lipoprotein cholesterol increased in all treatment groups compared to C. Changes were observed mostly in SE interventions, particularly in dyslipidemic subjects (p < 0.05). Spirulina maxima supplementation enhances the hypolipidemic effect of a systematic PEP in men with excess body weight and dyslipidemia.

scholarly journals Impact of Spirulina maxima Intake and Exercise (SIE) on Metabolic and Fitness Parameters in Sedentary Older Adults with Excessive Body Mass: Study Protocol of a Randomized Controlled Trial

2021 ◽  
Vol 18 (4) ◽  
pp. 1605
Author(s):  
Marco Antonio Hernández-Lepe ◽  
José de Jesús Manríquez-Torres ◽  
Omar Ramos-Lopez ◽  
Aracely Serrano-Medina ◽  
Melinna Ortiz-Ortiz ◽  
...  
Keyword(s):  
Older Adults ◽  
Body Mass ◽  
Study Protocol ◽  
Healthy Lifestyle ◽  
Controlled Trial ◽  
Exercise Program ◽  
Daily Practice ◽  
Spirulina Maxima ◽  
Double Blind ◽  
Fitness Parameters

Life expectancy has increased unprecedentedly in recent decades, benefiting the longevity of the world’s population. The most frequent pathological conditions presented in this age group include excessive body fat, frailty, and hypercholesterolemia. These pathological characteristics condition general health and autonomy in adults to carry out their usual activities. In this sense, the search for a healthy lifestyle is necessary, consisting in a healthy diet that includes supplementation with nutraceuticals and the daily practice of physical activity. This study protocol aims to evaluate the independent and synergistic effect of 12 weeks of Spirulina maxima intake (5 g/day), with or without an exercise program on metabolic and fitness parameters of 52 sedentary older adults with excessive body mass in a double-blind, randomized, crossover, controlled trial design. The main findings from this trial will provide novel evidence for future interventions designed for the elderly population and the result will be disseminated through peer-reviewed journals and international meetings. ClinicalTrials.gov identification number: NCT04658875 (Effect of Spirulina maxima and Exercise on General Fitness and Blood Lipids in Older Adults).

scholarly journals Systematic Physical Exercise and Spirulina maxima Supplementation Improve Body Composition, Cardiorespiratory Fitness, and Blood Lipid Profile: Correlations of a Randomized Double-Blind Controlled Trial

Antioxidants ◽  
2019 ◽  
Vol 8 (11) ◽  
pp. 507 ◽  
Author(s):  
Marco Antonio Hernández-Lepe ◽  
Francisco Javier Olivas-Aguirre ◽  
Luis Mario Gómez-Miranda ◽  
Rosa Patricia Hernández-Torres ◽  
José de Jesús Manríquez-Torres ◽  
...  
Keyword(s):  
Body Composition ◽  
Physical Exercise ◽  
Oxygen Uptake ◽  
Lipid Profile ◽  
Cardiorespiratory Fitness ◽  
Maximal Oxygen Uptake ◽  
Controlled Trial ◽  
Blood Lipid ◽  
Spirulina Maxima ◽  
Blood Lipid Profile

Cardiovascular diseases are part of the highly preventable chronic diseases associated with changes in lifestyle. Within them, physical activity, low-fat and high-fiber diets are distinguished as the main support for prevention, even when supplementation with nutraceuticals has become a very common practice. Fifty-two young sedentary men with excess body weight (body mass index (BMI) ≥ 25 kg·m−2) were enrolled in a randomized-crossover controlled trial [six weeks of a systematic physical exercise with Spirulina maxima or placebo supplementation (4.5 g·day−1)]. Body composition, blood lipid profile, and maximal oxygen uptake were determined pre/post intervention. Pairwise comparisons showed a significant improvement (p < 0.01) on blood lipid profile in the group of exercise plus Spirulina maxima. Moreover, correlations of absolute changes of BMI, body fat percentage, blood lipids and maximal oxygen uptake were statistically significant (p < 0.01). These results indicate that the Spirulina maxima supplementation could be acting in a synergistic way with exercise due to the enhanced effects on body composition, cardiorespiratory fitness, and blood lipid profile. This phenomenon should be considered to reduce risk of cardiovascular disorders. Trial registration: Clinical Trials, NCT02837666 (July 19, 2016).

scholarly journals Double-blind randomised controlled trial of the independent and synergistic effect of Spirulina maxima with exercise (ISESE) on general fitness, lipid profile and redox status in overweight and obese subjects: study protocol

BMJ Open ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. e013744 ◽  
Author(s):  
Marco Antonio Hernández-Lepe ◽  
José Alberto López-Díaz ◽  
Laura Alejandra de la Rosa ◽  
Rosa Patricia Hernández-Torres ◽  
Abraham Wall-Medrano ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Synergistic Effect ◽  
Lipid Profile ◽  
Study Protocol ◽  
Controlled Trial ◽  
Redox Status ◽  
Spirulina Maxima ◽  
Double Blind ◽  
Obese Subjects ◽  
Randomised Controlled

scholarly journals The effects of 14-week betaine supplementation on endocrine markers, body composition and anthropometrics in professional youth soccer players: a double blind, randomized, placebo-controlled trial

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Hadi Nobari ◽  
Mehdi Kargarfard ◽  
Vazgen Minasian ◽  
Jason M. Cholewa ◽  
Jorge Pérez-Gómez
Keyword(s):  
Body Composition ◽  
Controlled Trial ◽  
Exercise Program ◽  
Soccer Players ◽  
Double Blind ◽  
Significant Group ◽  
Youth Soccer ◽  
Professional Soccer ◽  
Competitive Season ◽  
Betaine Supplementation

Abstract Objective Betaine supplementation may enhance body composition outcomes when supplemented chronically during an exercise program. The purpose of this study was to evaluate the effect of betaine supplementation on development-related hormones, body composition, and anthropometrics in professional youth soccer players during a competitive season. Methods Twenty-nine players (age, 15.45 ± 0.25 years) were matched based upon position and then randomly assigned to a betaine group (2 g/day; n = 14, BG) or placebo group (PG, n = 15). All subjects participated in team practices, conditioning, and games. If a subject did not participate in a game, a conditioning protocol was used to ensure workload was standardized throughout the 14-week season. Growth hormone (GH), insulin-like growth factor-1 (IGF-1), testosterone, cortisol, height, weight, and body composition were assessed at pre-season (P1), mid-season (P2) and post-season (P3). Anthropometric variables were also measured following a one-year follow-up (F). Results Significant (p < 0.05) group x time interactions were found for testosterone and testosterone to cortisol ratio (T/C). Both variables were greater in BG at P2 and P3 compared to P1, however, the testosterone was less in the PG at P3 compared to P2. There was no significant group by time interactions for GH, IGF-1, lean body mass, or body fat. There was a significant (p < 0.05) group x time interaction in height and weight at F, with the greater increases in BG compared to PG. Conclusion Betaine supplementation increased testosterone levels and T/C ratio in youth professional soccer players during a competitive season. Betaine supplementation had no negative effects on growth (height and weight) and may attenuate reductions in testosterone due to intense training during puberty.

The Weight Loss Effects of Branched Chain Amino Acids and Vitamin B6: A Randomized Controlled Trial on Obese and Overweight Women

2018 ◽  
Vol 88 (1-2) ◽  
pp. 80-89 ◽  
Author(s):  
Zahra Shakibay Novin ◽  
Saeed Ghavamzadeh ◽  
Alireza Mehdizadeh
Keyword(s):  
Amino Acids ◽  
Weight Loss ◽  
Body Composition ◽  
Vitamin B6 ◽  
Controlled Trial ◽  
Density Lipoprotein ◽  
Branched Chain Amino Acids ◽  
Model Assessment ◽  
Waist To Hip Ratio ◽  
Branched Chain

Abstract. Branched chain amino acids (BCAA), with vitamin B6 have been reported to improve fat metabolism and muscle synthesis. We hypothesized that supplementation with BCAA and vitamin B6 would result in more weight loss and improve body composition and blood markers related to cardiovascular diseases. Our aim was to determine whether the mentioned supplementation would affect weight loss, body composition, and cardiovascular risk factors during weight loss intervention. To this end, we performed a placebo-controlled randomized clinical trial in 42 overweight and obese women (BMI = 25–34.9 kg/m2). Taking a four-week moderate deficit calorie diet (–500 kcal/day), participants were randomized to receive BCAA (6 g/day) with vitamin B6 (40 mg/day) or placebo. Body composition variables measured with the use of bioelectrical impedance analysis, homeostatic model assessment, and plasma insulin, Low density lipoprotein, High density lipoprotein, Total Cholesterol, Triglyceride, and fasting blood sugar were measured. The result indicated that, weight loss was not significantly affected by BCAA and vitamin B6 supplementation (–2.43 ± 1.02 kg) or placebo (–1.64 ± 1.48 kg). However, significant time × treatment interactions in waist to hip ratio (P = 0.005), left leg lean (P = 0.004) and right leg lean (P = 0.023) were observed. Overall, supplementation with BCAA and vitamin B6 could preserve legs lean and also attenuated waist to hip ratio.

scholarly journals Subcutaneous Oxyntomodulin Reduces Body Weight in Overweight and Obese Subjects: A Double-Blind, Randomized, Controlled Trial

Diabetes ◽  
2005 ◽  
Vol 54 (8) ◽  
pp. 2390-2395 ◽  
Author(s):  
K. Wynne ◽  
A. J. Park ◽  
C. J. Small ◽  
M. Patterson ◽  
S. M. Ellis ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Body Weight ◽  
Controlled Trial ◽  
Double Blind ◽  
Randomized Controlled ◽  
Obese Subjects

scholarly journals Analysis of the Impact of a Multi-Strain Probiotic on Body Composition and Cardiorespiratory Fitness in Long-Distance Runners

Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3758
Author(s):  
Joanna Smarkusz-Zarzecka ◽  
Lucyna Ostrowska ◽  
Joanna Leszczyńska ◽  
Karolina Orywal ◽  
Urszula Cwalina ◽  
...  
Keyword(s):  
Body Composition ◽  
Cardiorespiratory Fitness ◽  
The Body ◽  
Double Blind Study ◽  
Distance Runners ◽  
Long Distance ◽  
Double Blind ◽  
Necrosis Factor Alpha ◽  
Total Body ◽  
The Impact

Use of probiotic supplements, the benefits of which have not been proven in sportspeople, is becoming more widespread among runners. The aim of this study was to evaluate the effect of a multi-strain probiotic on body composition, cardiorespiratory fitness and inflammation in the body. The randomised, double-blind study included 66 long-distance runners. The intervention factor was a multi-strain probiotic or placebo. At the initial and final stages of the study, evaluation of body composition and cardiorespiratory fitness was performed and the presence of inflammation determined. In the group of men using the probiotic, an increase in lean body mass (p = 0.019) and skeletal muscle mass (p = 0.022) was demonstrated, while in the group of women taking the probiotic, a decrease in the content of total body fat (p = 0.600) and visceral fat (p = 0.247) was observed. Maximum oxygen consumption (VO2max) increased in women (p = 0.140) and men (p = 0.017) using the probiotic. Concentration of tumour necrosis factor-alpha decreased in women (p = 0.003) and men (p = 0.001) using the probiotic and in women (p = 0.074) and men (p = 0.016) using the placebo. Probiotic therapy had a positive effect on selected parameters of body composition and cardiorespiratory fitness of study participants and showed a tendency to reduce inflammation.

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