scholarly journals The Relationship of Modifiable Risk Factors with Indicators of Arterial Stiffness and Vascular Age in Patients with Arterial Hypertension

2021 ◽  
Vol 17 (1) ◽  
pp. 42-48
Author(s):  
A. M. Tuktarov ◽  
T. S. Kazanceva ◽  
A. E. Filippov ◽  
A. G. Obrezan
Keyword(s):  
Risk Factors ◽  
Arterial Stiffness ◽  
Arterial Hypertension ◽  
Pulse Wave ◽  
Modifiable Risk Factors ◽  
Hypertensive Patients ◽  
Vascular Age ◽  
The Mean ◽  
Relationship Of ◽  
The Relationship

Aim. To study the relationship of modifiable risk factors (RF) with indicators of arterial stiffness and vascular age based on the contour analysis of the pulse wave velocity in hypertensive patients.Material and methods. The material of the study was the data from a survey of patients undergoing clinical observation at the polyclinic of MMC SOGAZ. A total of 107 patients were examined, in which 70 were men and 37 were women. The average age was 52.3±18.29. Photoplethysmography was used as a special research method, performed using the AngioScan-01 diagnostic complex. The main indicators used to evaluate the stiffness of large vessels were: stiffness index (SI), reflection index (RI), augmentation index (Alp75), age index (AGI), pulse wave types (PV) and vascular age (VA).Results. The mean values of arterial stiffness indices in patients with essential arterial hypertension (AH) and healthy individuals (control) had significant differences. The mean SI, Alp75, and VA values in the group of patients with AH were 7.8±1.03, 7.0±14.44 and 50.8±15.93 versus 7.2±1.73, 0.5±18.02 and 43.8±16.94, respectively (p< 0.05). In both groups, a strong inverse correlation of passport age with C-type PV was revealed (r=0.74, p< 0.01), which reflected the dynamics of a gradual age-dependent decrease in vascular compliance. The average VA value in the control group was 63.1±16.99 years with an average passport age of 59.5±8.79 years, which significantly differed from VA in hypertensive patients (p< 0,05). Overweight, hypercholesterolemia, elevated low-density lipoprotein levels, lack of adequate antihypertensive control, and left ventricular diastolic dysfunction were significantly associated with early vascular (arterial) aging.Conclusion. Patients with hypertension, in addition to high blood pressure, significantly differ from normotensive control in terms of arterial stiffness. The lack of control over modifiable RF of patients with hypertension is associated with early vascular aging.

scholarly journals The Relationship of the Atlantic Diet with Cardiovascular Risk Factors and Markers of Arterial Stiffness in Adults without Cardiovascular Disease

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 742 ◽  
Author(s):  
Carmela Rodríguez-Martín ◽  
Luis Garcia-Ortiz ◽  
Emiliano Rodriguez-Sanchez ◽  
Carlos Maderuelo-Fernandez ◽  
Alba Lugones-Sanchez ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Pulse Wave ◽  
Diet And Physical Activity ◽  
Relationship Of ◽  
The Relationship

Background: Studying the adherence of the population to the Atlantic Diet (AD) could be simplified by an easy and quickly applied dietary index. The aim of this study is to analyse the relationship of an index measuring compliance with recommendations regarding the Atlantic diet and physical activity with cardiovascular disease risk factors, cardiovascular risk factors, obesity indexes and arterial stiffness markers. Methods: We included 791 individuals from the EVIDENT study (lifestyles and arterial ageing), (52.3 ± 12 years, 61.7% women) without cardiovascular disease. Compliance with recommendations on AD was collected through the responses to a food frequency questionnaire, while physical activity was measured by accelerometer. The number of recommendations being met was estimated using a global scale between 0 and 14 points (a higher score representing greater adherence). Blood pressure, plasma lipid and glucose values and obesity rates were measured. Cardiovascular risk was estimated with the Framingham equation. Results: In the overall sample, 184 individuals (23.3%) scored between 0–3 on the 14-point index we created, 308 (38.9%) between 4 and 5 points, and 299 (37.8%) 6 or more points. The results of multivariate analysis yield a common tendency in which the group with an adherence score of at least 6 points shows lower figures for total cholesterol (p = 0.007) and triglycerides (p = 0.002). Similarly, overall cardiovascular risk in this group is the lowest (p < 0.001), as is pulse wave velocity (p = 0.050) and the mean values of the obesity indexes studied (p < 0.05 in all cases). Conclusion: The rate of compliance with the Atlantic diet and physical activity shows that greater adherence to these recommendations is linked to lower cardiovascular risk, lower total cholesterol and triglycerides, lower rates of obesity and lower pulse wave velocity values.

EVALUATION OF THE VESSEL AGE BY APPLYING THE ACCELERATION PLETHYSMOGRAM ANALYSIS

2021 ◽  
pp. 61-67
Author(s):  
Елизавета Александровна Молчанова ◽  
Петр Вячеславович Лужнов
Keyword(s):  
Blood Vessels ◽  
Pulse Wave ◽  
Vascular System ◽  
Vascular Wall ◽  
Second Derivative ◽  
Contour Analysis ◽  
Physiological Factors ◽  
Vascular Age ◽  
Relationship Of ◽  
The Relationship

В работе приведены понятия жесткости, эластичности и тонуса сосудов, а также же их взаимосвязь с общим состоянием сосудистой стенки. Описан индекс, объединяющий влияние вышеперечисленных факторов на состояние сосудистой системы и дающий представление о возрасте сосудов пациента, а также показана связь этого индекса с возрастом человека. Представлен обзор способов определения возраста сосудов с помощью контурного анализа пульсовой волны. Среди предложенных способов был выделен подход на основе контурного анализа сигнала пульсовой волны, а также ее второй производной. В данном исследовании проводилась разработка алгоритма расчета показателя возраста сосудов (VA), базирующаяся на анализе сигнала и его второй производной. При этом особое внимание уделялось физической интерпретации параметров, входящих в состав расчетной формулы. С помощью представленного алгоритма в группе из трех испытуемых был определен сосудистый возраст. Из анализа полученных результатов было выявлено влияние физиологических факторов на значение возраста сосудов. Предложены методики, позволяющие исключить влияние этих факторов на значения показателя VA и тем самым получить более точные результаты. Также представлены стратегии дальнейшего развития исследований в этом направлении In The paper presents the concepts of rigidity, elasticity and tone of blood vessels, as well as their relationship with the general state of the vascular wall. An index is described that combines the influence of the above factors on the state of the vascular system and gives an idea of the age of the patient's vessels, and also shows the relationship of this index with the age of a person. An overview of the methods for determining the age of blood vessels using the contour analysis of the pulse wave is presented. Among the proposed methods, an approach based on the contour analysis of the pulse wave signal, as well as its second derivative, was singled out. In this study, an algorithm was developed for calculating the indicator of vascular age (VA), based on the analysis of the signal and its second derivative. In this case, special attention was paid to the physical interpretation of the parameters included in the calculation formula. Using the presented algorithm, vascular age was determined in a group of three subjects. From the analysis of the results obtained, the influence of physiological factors on the value of the age of the vessels was revealed. Methods are proposed that allow to exclude the influence of these factors on the values of the VA indicator and thereby obtain more accurate results. Also presented are strategies for the further development of research in this direction

Use of 99mTc-HMPAO Brain SPECT in Patients with Arterial Hypertension: Correlation with Cognitive Function

2015 ◽  
Vol 1084 ◽  
pp. 492-495
Author(s):  
Irina Yu. Efimova ◽  
Nataliya Yu. Efimova ◽  
Sergey V. Triss ◽  
Yuri B. Lishmanov
Keyword(s):  
Cognitive Function ◽  
Arterial Hypertension ◽  
Brain Perfusion ◽  
Brain Spect ◽  
Thought Processes ◽  
Psychomotor Speed ◽  
Hypertensive Patients ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain

Article focuses on the use of 99mTc-HMPAO brain SPECT for evaluation of cerebral blood flow in patients with arterial hypertension and identification of the relationship of brain perfusion and cognitive function. Using SPECT of brain with 99mTc-HMPAO it was found out that hypertensive patients even in the absence of focal neurological symptoms have hypoperfusion of the brain which leads to cognitive dysfunction: decreased attention, psychomotor speed and slow thought processes.

The Role of Adipokines in the Development of Arterial Stiffness and Hypertension

Angiology ◽  
2020 ◽  
Vol 71 (8) ◽  
pp. 754-761
Author(s):  
Agata Bielecka-Dabrowa ◽  
Marcin A. Bartlomiejczyk ◽  
Agata Sakowicz ◽  
Marek Maciejewski ◽  
Maciej Banach
Keyword(s):  
Arterial Stiffness ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Elevated Serum ◽  
Control Group ◽  
Newly Diagnosed ◽  
Potential Mechanism ◽  
Relationship Of ◽  
The Relationship

The study aimed to assess the role and the relationship of adipokines as well as parameters of arterial stiffness in newly diagnosed hypertension. Forty-nine newly diagnosed hypertensive cases (median age 47 ± 6 years) and 48 normotensive patients (median age 47 ± 6 years) were enrolled to this study. Patients underwent echocardiography, noninvasive assessment of hemodynamic parameters using SphygmoCor tonometer (Atcor Med). The levels of the adipokines—leptin, adiponectin, and resistin—were investigated. The augmentation pressure, augmentation index, and pulse wave velocity (PWV) were higher in patients with hypertension compared with controls ( Ps < .05). Patients with hypertension had higher E/ E′ ratio, higher diameter of left atrium, and lower tricuspid annular plane systolic excursion compared with the control group ( Ps < .05). Patients with hypertension had significant higher levels of leptin (ng/mL) and lower levels of adiponectin (μg/mL) compared with normotensive patients. The multivariate analysis showed that PWV (odds ratio [OR] 1.95, 95% CI, 1.2-2.9; P = .002) and leptin level (OR 1.01, 95% CI, 1.004-1.031; P = .01) were significantly associated with hypertension. Arterial stiffness as determined by PWV and leptin are associated with newly diagnosed hypertension. Elevated serum leptin level may influence the potential mechanism leading to sympathetic activation.

scholarly journals Association of self-reported sleep duration and quality with BaPWV levels in hypertensive patients

2020 ◽  
Vol 43 (12) ◽  
pp. 1392-1402
Author(s):  
Huan Hu ◽  
Huan Li ◽  
Xiao Huang ◽  
Huihui Bao ◽  
Yun Song ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Sleep Quality ◽  
Sleep Duration ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Sectional Analysis ◽  
Relationship Of ◽  
The Relationship

AbstractThe association between sleep conditions and arterial stiffness remains inconclusive. We aimed to investigate the relationship of sleep duration and quality with brachial-ankle pulse-wave velocity (baPWV) in hypertensive patients. A total of 14,485 hypertensive adults were included in this cross-sectional analysis. Information about sleep duration and quality was obtained via questionnaire. A baPWV level ≥1800 cm/s was defined as indicative of arterial stiffness. Compared with participants with a sleep duration <8 h per day, participants with a sleep duration ≥8 h per day had a significantly higher baPWV level (β = 13.7 cm/s; 95% CI: 3.9, 23.5) and a nonsignificantly higher prevalence of arterial stiffness (39.7% vs. 33.0%; OR, 1.08; 95% CI: 0.99–1.19). Similarly, compared with participants with good or medium sleep quality, participants with poor sleep quality had a significantly higher baPWV level (β = 16.3 cm/s; 95% CI: 0.1, 32.6) and a nonsignificantly greater prevalence of arterial stiffness (36.6% vs. 35.3%; OR, 1.13; 95% CI: 0.97–1.32). When sleep duration and quality were examined jointly, participants with a sleep duration ≥8 h and/or poor sleep quality had a significantly higher baPWV level (β = 14.4 cm/s; 95% CI: 5.3, 23.4) and a greater prevalence of arterial stiffness (38.8% vs. 32.7%; OR, 1.10; 95% CI: 1.01–1.20) than those with a sleep duration <8 h and good/medium sleep quality. In summary, among hypertensive patients, a longer sleep duration (≥8 h per day) and poor sleep quality were associated with higher baPWV levels and a higher prevalence of arterial stiffness.

scholarly journals Study of the relationship social and psychological characteristics of hypertensive patients, the frequency of medical emergencies and adherence of patients to treatment

2014 ◽  
Vol 11 (2) ◽  
pp. 5-8
Author(s):  
E A Chumakova ◽  
N I Gaponova
Keyword(s):  
Arterial Hypertension ◽  
Antihypertensive Drugs ◽  
Psychological Characteristics ◽  
Social Characteristics ◽  
Hypertensive Patients ◽  
Medical Emergencies ◽  
Medical Recommendations ◽  
Relationship Of ◽  
The Relationship ◽  
Active Patients

The aim of the study was to investigate the relationship of psychological and social characteristics of patients with hypertension often seek emergency medical help with their adherence to treatment.Material and methods. Outpatient were examined 300 patients with hypertension (100 men and 200 women) from 35 years and older (mean age 72,1±12,8 years). Duration of hypertension ranged from 4 to 36 years old. We excluded patients with symptomatic arterial hypertension. Using questionnaires, revealed frequency of calls ambulance, the extent to which medical recommendations and regularity of antihypertensive drugs by patients. Also completed questionnaires Spielberg- Hanin for the assessment of emotional status.Results. The study showed that more frequent calls in general are more common in women than men, single patients, compared to unmarried as well as retirees compared to active patients. The proportion of women callers ambulance at least 1 time per year was 29% and was significantly (p

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