scholarly journals Faktor Risiko Tuberculosis Paru di Kabupaten Rejang Lebong

2007 ◽  
Vol 2 (3) ◽  
pp. 112
Author(s):  
Demsa Simbolon

Di Kabupaten Rejang Lebong, sejak tahun 1995 telah dilaksanakan kegiatan pemberantasan TB Paru dengan strategi DOTS, tetapi penderita baru tetap di temukan dan memperlihatkan trend yang meningkat dari tahun ke tahun. Penelitian ini bertujuan untuk mengetahui faktor risiko yang berhubungan dengan kejadian TB paru BTA (+) di Kabupaten Rejang Lebong. Desain penelitian yang digunakan aalah disain kasus kontrol. Kelompok kasus adalah penderita TB Paru BTA (+) berumur ³15 tahun yang berobat pada Oktober 2005 sampai Mei 2006. Kontrol adalah tetangga kasus yang tidak mempunyai tanda-tanda gejala klinis TB paru dengan golongan umur ³15 tahun. Jumlah sampel sebanyak 50 kasus dan 50 kontrol dengan teknik stratified Random Sampling. Analisis data menggunakan metode regresi logistik ganda. Hasil penelitian menemukan bahwa faktor risiko kejadian TB Paru jika tidak pernah di imunisasi BCG (OR=2,855, P=0,048), ada sumber kontak (OR=2,263, P=0,046), luas ventilasi rumah kurang dari 10% luas lantai (OR=4,907, P=0,004), tidak ada cahaya matahari masuk ke rumah (OR=5,008, P=0,006), interaksi antara perilaku merokok dengan penghuni rumah padat serta keeratan kontak (OR=14,576, P=0,017). Faktor yang paling dominan adalah interaksi perilaku merokok dan penghuni rumah yang padat. Probabilitas seseorang mengalami TB paru denganfaktor risiko adalah 98%.Kata kunci: TBC, faktor risiko, sumber penular, lingkunganAbstractSince 1995, eradication program of Pulmonary Tuberculosis with strategy of DOTS have been executed in Rejang Lebong District, but new patient remain to occur and showing tendency of increasing from year to year. The objective of this study is to know risk factor related to occurence of Pulmonary Tuberculosis BTA (+) in Rejang Lebong District. This research use case control study with comparison 1:1. Case is patient of Pulmonary Tuberculosis BTA (+) residing in working areas of Puskesmas Curup, Perumnas and Puskesmas Kampung Delima age >15 year, who seek medical treatment within October 2005 to May 2006, with exclusion criteria of not being relapsing TB patient. Control is neighbor of case who don’t have symptom of clinical Pulmonary Tuberculosis of the same age with cases. Research was conducted in May-July 2006 with 50 cases and 50 controls. Data analysis used in this study is multivariate logistic regression. The study has found that risk factor related to occurrence of Pulmonary Tuberculosis is not BCG immunized (OR=2.855, p=0.048), source of infection (OR=2.263, p=0.046), ventilation less than 10% of wide floor (OR=4.907, p=0.004), no sunlight into the house (OR=5.008, p=0.006), interaction between smoking behavior with house density, and closeness of contact (OR=14.576, P=0.017). The most dominant factor is interaction between smoking behavior with house density.Keywords : Pulmonary tuberculosis, risk factors, source of infection, housing environment

PLoS ONE ◽  
2011 ◽  
Vol 6 (8) ◽  
pp. e24215 ◽  
Author(s):  
Daniel Faurholt-Jepsen ◽  
Nyagosya Range ◽  
George PrayGod ◽  
Kidola Jeremiah ◽  
Maria Faurholt-Jepsen ◽  
...  

2017 ◽  
Vol 5 (1) ◽  
pp. 68
Author(s):  
Kanella Ayu Wulanuari ◽  
Anggi Napida Anggraini ◽  
Suparman Suparman

<em>A study by UNICEF in Indonesia find that the number of early marriage for 15 years old is 11% and 18 years is 35%. Generally, early marriage is more common in women than men, it’s approximately 5% of boys get married before they are 19 years old. The purpose of this study was to determine factors relating to early marriage in women and the most significant factor relating to early marriage. The study used observational quantitative study with case-control study design. The population of the study was 132 married women, samples were selected by using total sampling technique with the inclusion and exclusion criteria. The respondents of this study were 53 women. Data were analysis by chi square test and logistic regression. The results of chi-square test showed variables that had relationship with early marriage were respondents' education (p=0.035), respondents’ income (p=0.000), and sexual pre marriage (p=0.006) whereas variables that did not have relationship with early marriage are father's education (p=0.436), mother’s education (p=0.290), parents’ income (p=0.356) and respondents’ religiosity (p=0.489). The result of logistic regression analysis showed that respondents’ income was the most dominant factor affecting early marriage in women. Conclusion the most significant factor related to early marriage was respondents’ income.</em>


2021 ◽  
Author(s):  
Michael N. Bates ◽  
Karl Pope ◽  
Tula R. Sijali ◽  
Autumn E. Albers ◽  
Sharat C. Verma

2021 ◽  
pp. 100776
Author(s):  
Flora Martinez Figueira Moreira ◽  
Renu Verma ◽  
Paulo Cesar Pereira dos Santos ◽  
Alessandra Leite ◽  
Andrea da Silva Santos ◽  
...  

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 973-973
Author(s):  
R. Gonzalez Mazario ◽  
J. J. Fragio-Gil ◽  
P. Martinez Calabuig ◽  
E. Grau García ◽  
M. De la Rubia Navarro ◽  
...  

Background:Cardiovascular disease (CV) is the most frequent cause of death in rheumatoid arthritis (RA) patients. It is well known that RA acts as an independent cardiovascular risk factor.Objectives:To assess the CV risk in RA patients using carotid ultrasonography (US) additionally to the traditional CV risk factors.Methods:A prospective transversal case control study was performed, including adult RA patients who fulfilled ACR/EULAR 2010 criteria and healthy controls matched according to CV risk factors. Population over 75 years old, patients with established CV disease and/or chronic kidney failure (from III stage) were excluded. The US evaluator was blinded to the case/control condition and evaluated the presence of plaques and the intima-media thickness. Statistical analysis was performed with R (3.6.1 version) and included a multivariate variance analysis (MANOVA) and a negative binomial regression adjusted by confounding factors (age, sex and CV risk factors).Results:A total of 200 cases and 111 healthy controls were included in the study. Demographical, clinical and US data are exposed in table 1. Not any difference was detected in terms of CV risk factors between the cases and controls. In both groups a relationship between age, BMI and high blood pressure was detected (p<0.001).Table 1.Table 2.RA basal characteristicsDisease duration (years)16,98 (11,38)Erosions (X-Ray of hands/feet)163 (81,5%)Seropositive (RF/anti-CCP)146 (73%)Extra-articular symptoms44 (22%)Intersticial difusse lung disease10 (5%)Rheumatoid nodules14 (7%)Prednisone use103 (51,5%)Median dose of Prednisone last year (mg)2,34 (2,84)sDMARDsMethotrexate104 (52%)Leflunomide29 (14,5%)Hydroxycloroquine9 (4,5%)bDMARDs89 (44,5%) TNFi41 (20,5%) Abatacept15 (7,5%) IL6i22 (11%) RTX11 (5,5%)JAKi26 (13%) Baricitinib11 (5,5%) Tofacitinib15 (7,5%)DAS 28-ESR3,1 (2,3, 3,9)SDAI7,85 (4,04, 13,41)HAQ0,88 (0,22, 1,5)RF (U/mL)51 (15, 164,25)Anti-CCP (U/mL)173 (22, 340)Patients showed higher intima-media (both right and left) thickness compared to controls (p<0.006). Moreover it was also related to the disease duration and DAS28 score (p<0.001). A higher plaque account was noted in cases(p<0.004) and it was also related to the disease duration (p<0.001).Conclusion:RA implies a higher CV risk. Traditional CV risk factors explains only partially the global risk. These findings support that RA acts as an independent cardiovascular risk factor.Disclosure of Interests:None declared


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