scholarly journals The Relationship between Dietary Patterns and Depression is mediated by Serum Level of Folate and Vitamin B12: A Case-Control Study

2020 ◽  
Author(s):  
Maryam Khosravi ◽  
Gity Sotoudeh ◽  
Maryam Amini ◽  
Firoozeh Raisi ◽  
Anahita Mansoori ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Folate ◽  
Folate And Vitamin B12 ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract Background: Major depressive disorder is among main worldwide causes of disability. The low medication compliance rates in depressed patients as well as the high recurrence rate of the disease can bring up the nutrition-related factors as a potential preventive or treatment agent for depression. The aim of this study was to investigate the association between dietary patterns and depression via the intermediary role of the serum folate and vitamin B12, total homocysteine, tryptophan, and tryptophan/competing amino acids ratio. Methods This was an individually matched case-control study in which 110 patients with depression and 220 healthy individuals, who completed a semi-quantitative food frequency questionnaire were recruited. In addition, to measure the serum biomarkers 43 patients with depression and 43 healthy people were randomly selected from the study population. To diagnose depression the criteria of Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were utilized. Results The findings suggest that the healthy dietary pattern was significantly associated with a reduced odds of depression (OR: 0.75; 95% CI: 0.61-0.93) whereas the unhealthy dietary pattern increased it (OR: 1.382, CI: 1.116–1.71). The mediation analysis showed that the healthy dietary pattern was associated with a reduced risk of depression via increased serum levels of the folate and vitamin B12; however, the unhealthy dietary pattern was associated with increased risk of depression via decreased serum levels of folate and vitamin B12, based on tree adjusted logistic regression models. Conclusion Dietary patterns may be associated with depression by changing the serum levels of folate and vitamin B12. Further studies are required to confirm the mechanism.

scholarly journals The Relationship between Dietary Patterns and Depression is mediated by Serum Level of Folate and Vitamin B12: A Case-Control Study

2019 ◽  
Author(s):  
Maryam Khosravi ◽  
Gity Sotoudeh ◽  
Maryam Amini ◽  
Firoozeh Raisi ◽  
Anahita Mansoori ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Folate ◽  
Folate And Vitamin B12 ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract Introduction Major depressive disorder is among main worldwide causes of disability. The low medication compliance rates in depressed patients as well as the high recurrence rate of the disease can bring up the nutrition-related factors as a potential preventive or treatment agent for depression. The aim of this study was to investigate the association between dietary patterns and depression via the intermediary role of the serum folate and vitamin B12, total homocysteine, tryptophan, and tryptophan/competing amino acids ratio. Methods This was an individually matched case-control study in which 110 patients with depression and 220 healthy individuals, who completed a semi-quantitative food frequency questionnaire were recruited. In addition, to measure the serum biomarkers 43 patients with depression and 43 healthy people were randomly selected from the study population. To diagnose depression the criteria of Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were utilized. Results The findings suggest that the healthy dietary pattern was significantly associated with a reduced odds of depression (OR: 0.75; 95% CI: 0.61-0.93) whereas the unhealthy dietary pattern increased it (OR: 1.382, CI: 1.116–1.71). The mediation analysis showed that the healthy dietary pattern was associated with a reduced risk of depression via increased serum levels of the folate and vitamin B12; however, the unhealthy dietary pattern was associated with increased risk of depression via decreased serum levels of folate and vitamin B12, based on tree adjusted logistic regression models. Conclusion Dietary patterns may be associated with depression by changing the serum levels of folate and vitamin B12. Further studies are required to confirm the mechanism.

scholarly journals The Relationship between Dietary Patterns and Depression is mediated by Serum Level of Folate and Vitamin B12: A Case-Control Study

2019 ◽  
Author(s):  
Maryam Khosravi ◽  
Gity Sotoudeh ◽  
Maryam Amini ◽  
Firoozeh Raisi ◽  
Anahita Mansoori ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Folate ◽  
Folate And Vitamin B12 ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract Introduction Major depressive disorder is among main worldwide causes of disability. The low medication compliance rates in depressed patients as well as the high recurrence rate of the disease can bring up the nutrition-related factors as a potential preventive or treatment agent for depression. The aim of this study was to investigate the association between dietary patterns and depression via the intermediary role of the serum folate and vitamin B12, total homocysteine, tryptophan, and tryptophan/competing amino acids ratio. Methods This was an individually matched case-control study in which 110 patients with depression and 220 healthy individuals, who completed a semi-quantitative food frequency questionnaire were recruited. In addition, to measure the serum biomarkers 43 patients with depression and 43 healthy people were randomly selected from the study population. To diagnose depression the criteria of Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were utilized. Results The findings suggest that the healthy dietary pattern was significantly associated with a reduced odds of depression (OR: 0.75; 95% CI: 0.61-0.93) whereas the unhealthy dietary pattern increased it (OR: 1.382, CI: 1.116–1.71). The mediation analysis showed that the healthy dietary pattern was associated with a reduced risk of depression via increased serum levels of the folate and vitamin B12; however, the unhealthy dietary pattern was associated with increased risk of depression via decreased serum levels of folate and vitamin B12, based on tree adjusted logistic regression models. Conclusion Dietary patterns may be associated with depression by changing the serum levels of folate and vitamin B12. Further studies are required to confirm the mechanism.

scholarly journals The Relationship between Dietary Patterns and Depression is mediated by Serum Level of Folate and Vitamin B12: A Case-Control Study

2020 ◽  
Author(s):  
Maryam Khosravi ◽  
Gity Sotoudeh ◽  
Maryam Amini ◽  
Firoozeh Raisi ◽  
Anahita Mansoori ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Folate ◽  
Folate And Vitamin B12 ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract Background: Major depressive disorder is among main worldwide causes of disability. The low medication compliance rates in depressed patients as well as the high recurrence rate of the disease can bring up the nutrition-related factors as a potential preventive or treatment agent for depression. The aim of this study was to investigate the association between dietary patterns and depression via the intermediary role of the serum folate and vitamin B12, total homocysteine, tryptophan, and tryptophan/competing amino acids ratio. Methods This was an individually matched case-control study in which 110 patients with depression and 220 healthy individuals, who completed a semi-quantitative food frequency questionnaire were recruited. In addition, to measure the serum biomarkers 43 patients with depression and 43 healthy people were randomly selected from the study population. To diagnose depression the criteria of Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were utilized. Results The findings suggest that the healthy dietary pattern was significantly associated with a reduced odds of depression (OR: 0.75; 95% CI: 0.61-0.93) whereas the unhealthy dietary pattern increased it (OR: 1.382, CI: 1.116–1.71). The mediation analysis showed that the healthy dietary pattern was associated with a reduced risk of depression via increased serum levels of the folate and vitamin B12; however, the unhealthy dietary pattern was associated with increased risk of depression via decreased serum levels of folate and vitamin B12, based on tree adjusted logistic regression models. Conclusion Dietary patterns may be associated with depression by changing the serum levels of folate and vitamin B12. Further studies are required to confirm the mechanism.

scholarly journals The relationship between dietary patterns and rheumatoid arthritis: a case–control study

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Shokufeh Nezamoleslami ◽  
Reza Ghiasvand ◽  
Awat Feizi ◽  
Mansour Salesi ◽  
Makan Pourmasoumi
Keyword(s):  
Rheumatoid Arthritis ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Case Control ◽  
Inverse Association ◽  
Western Dietary Pattern ◽  
Increased Risk ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract Background and aim A number of studies have investigated the effects of individual foods and/or nutrients on rheumatoid arthritis (RA), but research focusing on whole dietary patterns remains limited. The association of dietary patterns and rheumatoid arthritis is therefore not well elucidated. This study aims to determine existing relationships between major identified dietary patterns and RA. Methods This matched case–control study was conducted on 297 individuals in Isfahan, Iran. The presence of RA was determined by an expert rheumatologist, based on the American College of Rheumatology definitions, 2010. A 168-item questionnaire was used to collect dietary data. Major dietary patterns were identified using the factor analysis method. Results Two major dietary patterns, namely, healthy and western dietary patterns, were identified. Lower adherence to the healthy dietary pattern was associated with increased risk of RA (OR = 2.80; 95% CI 1.74–4.67; P < 0.001). The association remained significant even after taking other confounders into account (OR = 2.85; 95% CI 1.12–7.45; P = 0.03). A positively significant association was also observed between adherence to western dietary pattern and RA in the fully-adjusted final model (OR = 2.22; 95% CI 1.04–4.72; P = 0.03). Conclusions The study suggests that there is an inverse association between adherence to a healthy dietary pattern and the odds of RA, and a positive significant relationship was found between western dietary pattern and RA. Further studies are required to confirm these findings.

A healthy dietary pattern may be associated with primary insomnia among Iranian adults: A case-control study

2020 ◽  
pp. 1-12
Author(s):  
Samaneh Sadat ◽  
Ammar Salehi-sahlabadi ◽  
Makan Pourmasoumi ◽  
Awat Feizi ◽  
Cain C. T. Clark ◽  
...  
Keyword(s):  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Principal Component ◽  
Severity Index ◽  
Case Control ◽  
Primary Insomnia ◽  
Health Centers ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract. Objective: While it has been reported that both foods and nutrients for individuals are connected with sleep, there is no evidence regarding the association of dietary patterns, identified by factor analysis, with primary insomnia. The present study sought to evaluate the association between major dietary patterns and the chance of having primary insomnia. Methods: The present case-control study was performed using 444 people (111 cases and 333 control), aged 18 to 60 years, referred to Isfahan health centers. Dietary intake was assessed via a food frequency questionnaire in a case-control study in Isfahan, Iran. Principal component analysis was used to determine major dietary patterns. The presence of primary insomnia was measured via the insomnia severity index questionnaire, and the subjects were grouped as healthy or insomniac. Results: Three major dietary patterns were recognized, and named; Western, Iranian Traditional and Healthy, respectively. The cumulative percentage of variance explained by three dietary patterns was 48.2%. Those in second (OR = 0.30; 95%CI: 0.2–0.46) and third (OR = 0.22; 95%CI: 0.15–0.35) tertiles of healthy dietary pattern were less likely suffer with insomnia. This association remained significant only in the highest tertile after adjusting potential confounders (OR = 0.45; 95%CI: 0.32–0.95). We found no significant association between greater adherence to Western or Iranian traditional dietary patterns and primary insomnia. Conclusions: The findings showed that although no statistically significant association was observed between both Western and Iranian traditional dietary patterns with primary insomnia, people with greater adherence to the healthy dietary pattern are less likely to have primary insomnia.

scholarly journals Dietary patterns and benign breast diseases: a case–control study

2016 ◽  
Vol 116 (2) ◽  
pp. 353-359 ◽  
Author(s):  
Zeinab Tiznobeyk ◽  
Zahra Sheikhi Mobarakeh ◽  
Mostafa Qorbani ◽  
Fariba Koohdani ◽  
Gity Sotoudeh ◽  
...  
Keyword(s):  
Dietary Patterns ◽  
Dietary Pattern ◽  
Dairy Products ◽  
Case Control Study ◽  
Case Control ◽  
Breast Diseases ◽  
Benign Breast Diseases ◽  
Academic Center ◽  
Control Study ◽  
Healthy Dietary Pattern

AbstractSeveral studies have investigated the relation between benign breast diseases (BBD) and food intake. However, dietary patterns of these patients have not been taken into consideration up to now. The aim of this study is to determine the association between dietary patterns and BBD. In this case–control study, ninety-six patients with BBD and seventy controls were selected from women attending the Iranian Center for Breast Cancer affiliated with Academic Center for Education, Culture and Research. Demographic, physical activity and semi-quantitative FFQ were completed. The main dietary patterns were extracted by factor analysis. Two major dietary patterns emerged: Healthy dietary pattern including fish, poultry, eggs, low-fat dairy products, vegetables, legumes, nuts and seeds, whole grains, oil and mayonnaise, olives, fruits; and Unhealthy dietary pattern including red meats, organ and processed meats, high-fat dairy products, refined grains, sweets and desserts, animal and solid fats. After adjustment for age, BMI and energy intake, the participants in the highest tertile of Healthy dietary pattern (OR 0·44; 95 % CI 0·20, 0·99) were less likely to have BBD compared with those in the first tertile. After adjustment for other confounding variables, this relationship still remained close to significant level. However, higher consumption of Unhealthy dietary pattern was not associated with the risk of BBD. In conclusion, Healthy dietary pattern might be inversely associated with the risk of BBD; however, this result should be interpreted with caution. Future studies are needed to confirm our findings.

scholarly journals The relationship between major dietary patterns and fertility status in iranian men: a case–control study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Farahnaz Haeri ◽  
Makan Pourmasoumi ◽  
Reza Ghiasvand ◽  
Awat Feizi ◽  
Amin Salehi-Abargouei ◽  
...  
Keyword(s):  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Case Control ◽  
World Health ◽  
Inverse Association ◽  
Fertility Status ◽  
Increased Risk ◽  
Control Study ◽  
Healthy Dietary Pattern

AbstractIn this case–control study, we aimed to investigate the association between major dietary patterns and fertility status in Iranian men. The study population included 400 newly diagnosed infertile men and 537 healthy individuals without a history of infertility in Yazd, Iran. Infertility was confirmed clinically, based on the World Health Organization (WHO) criteria. Dietary intake was assessed using a 168-item semi-quantitative food frequency questionnaire (FFQ), and dietary patterns were determined based on a principal component analysis. Four major dietary patterns were found in this study, including healthy, Western, mixed, and traditional dietary patterns. After adjustments for potential confounders, men above the median of a healthy dietary pattern showed a reduced risk of infertility compared to those below the median (OR 0.52; 95% CI 0.33–0.83). In contrast, men with greater adherence to Western and mixed dietary patterns were more likely to be infertile (OR 2.66; 95% CI 1.70–4.17 and OR 2.82; 95% CI 1.75–4.56, respectively). Also, there was no significant association between the traditional dietary pattern and the odds of infertility. The present study suggests that greater adherence to a healthy dietary pattern may have an inverse association with the odds of infertility; however, Western and mixed dietary patterns may be associated with an increased risk of infertility.

scholarly journals Serum vitamin-mineral profiles – association with breast cancer risk including dietary patterns and supplements use: a case-control study

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Beata Krusinska ◽  
Lidia Wadolowska ◽  
Malgorzata Anna Slowinska ◽  
Maciej Biernacki ◽  
Marek Drozdowski
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Dietary Patterns ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Serum Folate ◽  
Serum Concentrations ◽  
25 Oh Vitamin D ◽  
Control Study

AbstractBreast cancer is the most diagnosed cancer among women worldwide. Studies regarding diet and blood levels of vitamins and minerals in the breast cancer aetiology are limited and the results are inconclusive. We investigated the association between serum vitamin-mineral profiles (V-MPs) and breast cancer (BC) risk with including dietary patterns (DPs) and use of supplements. This case-control study involved 420 women aged 40–79 years from north-eastern Poland, including 190 newly-diagnosed breast cancer cases. The serum concentrations of vitamins (folate, cobalamin, 25(OH) vitamin D) and minerals (iron, calcium, magnesium) were marked in 129 post-menopausal women (82 controls, 47 cases) using an immune-analyser Cobas e411 and a Cobas Integra 400plus auto-analyser (Roche Diagnostics®), respectively. A posteriori V-MPs were derived with a Principal Component Analysis (PCA). Three PCA-driven DPs: ‘Non-Healthy’, ‘Prudent’, and ‘Margarine and Sweetened Dairy’ were described previously. A logistic regression analysis was performed. The odds ratios (ORs) and 95% confidence interval (95% CI) were calculated. Two serum V-MPs were identified. The ‘Folate-Cobalamin-Vitamin D’ profile was loaded heavily by the folate (factor loading 0.82), cobalamin (0.81) and vitamin D (0.49). The ‘Iron-Calcium’ profile was loaded heavily by the iron (0.81) and calcium (0.77). The ‘Magnesium-vitamin D’ profile was loaded heavily by the magnesium (0.92) and vitamin D (0.39). The risk of BC was lower by 88% (OR: 0.12; 95%Cl: 0.02–0.88; p < 0.05) in the upper tertile of the serum ‘Iron-Calcium’ profile compared to the bottom tertile. The risk of BC was lower by 67% (OR: 0.33; 95%Cl: 0.11–0.97; p < 0.05) at the level of serum 25(OH) vitamin D ≥ 24.6 ng/mL and lower by 68% (OR: 0.32; 95%Cl: 0.11–0.91; p < 0.05) at the level of serum calcium ≥ 9.6 mg/dL. There was the inverse association of the serum ‘Magnesium-Vitamin D’ profile with the risk of BC, which disappeared after adjustment for DPs. No significant association between BC risk and the serum ‘Folate-Cobalamin-Vitamin D’ profile and also folate, cobalamin, iron or magnesium considered separately was revealed. These findings highlight that the higher-adequate serum concentrations of both iron and calcium as well as close-to-adequate concentrations of calcium and vitamin D considered separately may protect against breast cancer among postmenopausal women, independently of dietary patterns and use of supplements. Therefore, women should be screened for blood concentrations of multiple vitamins and minerals in the breast cancer prevention.

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