scholarly journals Economic costs incurred by the patients with Multiple Sclerosis at different levels of the disease: a cross-sectional study in northwest Iran

2020 ◽  
Author(s):  
Ali Imani ◽  
Farid Gharibi ◽  
Ali Khezri ◽  
Nasrin Joudyian ◽  
Koustuv Dalal

Abstract Background Multiple sclerosis (MS) causes significant economic burden to the patients, families, health systems and society. This study aimed to estimate the economic costs incurred by patients with multiple sclerosis at different levels of the disease.Method This was a cross-sectional study, using the Expanded Disability Status Scale (EDSS) tool for assessing the disease level of 300 (=N) patients in East Azerbaijan province, Iran. To estimate the cost of MS, a questionnaire with its validity and reliability (CVR 92% and CVI 87%) and pilot test (Cronbach's alpha score 0.89) was used. The data were collected by interviewing patients and reviewing their clinical records. Linear regression and ANOVA were used to assess the relationship between disease levels and incurred costs.Results The results revealed that the mean annual cost for patients is 97,521,740 IRR (equivalent to 2,321.94 USD) and the mean score of EDSS in patients was 3.14. The annual cost incurred by patients with mild, moderate and severe levels of disease were 83,918,150 IRR (998.05 USD), 137,772,660 IRR (3,280.30 USD) and 119,962,670 IRR (2,856.25 USD) respectively. Also, there was a significant relationship between total cost and disease severity in such a way that any increase in EDSS degree is led to 8,139,260 IRR (193.79 USD) added cost for patients.Conclusion The study results could be helpful for Iranian health managers to solve problems which are facing patients and their families.

2019 ◽  
Author(s):  
Ali Imani ◽  
Farid Gharibi ◽  
Ali Khezri ◽  
Nasrin Joudyian ◽  
Koustuv Dalal

Abstract Background Multiple sclerosis (MS) causes significant economic burden to the patients, families, health systems and society. This study aimed to estimate the economic costs incurred by patients with multiple sclerosis at different levels of the disease.Method This was a cross-sectional study, using the Expanded Disability Status Scale (EDSS) tool for assessing the disease level of 300 (=N) patients in East Azerbaijan province, Iran. To estimate the cost of MS, a questionnaire with its validity and reliability (CVR 92% and CVI 87%) and pilot test (Cronbach's alpha score 0.89) was used. The data were collected by interviewing patients and reviewing their clinical records. Linear regression and ANOVA were used to assess the relationship between disease levels and incurred costs.Results The results revealed that the mean annual cost for patients is 97,521,740 IRR (equivalent to 2,321.94 USD) and the mean score of EDSS in patients was 3.14. The annual cost incurred by patients with mild, moderate and severe levels of disease were 83,918,150 IRR (998.05 USD), 137,772,660 IRR (3,280.30 USD) and 119,962,670 IRR (2,856.25 USD) respectively. Also, there was a significant relationship between total cost and disease severity in such a way that any increase in EDSS degree is led to 8,139,260 IRR (193.79 USD) added cost for patients.Conclusion The study results could be helpful for Iranian health managers to solve problems which are facing patients and their families.


2021 ◽  
Vol 15 (5) ◽  
pp. 1399-1402
Author(s):  
H. J. Mahmood ◽  
R. H. Ibrahim ◽  
M. F. Abdulghani ◽  
Z. F. Al-Zaidy

Background and aim: The Objectives of the present study to determine the VV among people with different background occupations in the City of Mosul, Iraq. Materials and method: A cross-sectional study was performed at Mosul Teaching Hospital between November 2019 and February 2020. Two hundred people who were physically examined represented different jobs in Iraqi society (Nurses, address, Policemen, and teachers). A physical examination was conducted of all participants who agreed to engage in this study. Results: The overall prevalence rate of VV among different occupational backgrounds in the City of Mosul is 19.5%. The study found that the percentage of men (50.5%) and women (49.5%). Most of the patient was beyond to age group (41-45) years and the mean age of the participants was (39.1+3.1). According to the BMI, the results indicated that most subjects belong to a class<30 (77%). Conclusions: The nurses will seek to prevent excessive extended occupational standing and using sitting or walking when appropriate. As a result, an improvement in clinical practice may reduce the incidence of vascular disease. Keywords: Varicose, Veins, Occupational


2020 ◽  
Author(s):  
Niloofar Namazi ◽  
Shadi Ziaei ◽  
Golnaz Afzal ◽  
Saghar Barati ◽  
Rezvaneh Mohebbi ◽  
...  

Abstract BackgroundThe main objectives of this study were to assess quality of life (QoL), consumption patterns of dietary supplements, as well as physical/mental health status in patients with multiple sclerosis (MS). The present study also aimed to determine the association between demographic characteristics and physical as well as mental health composite (PHC and MHC) scores using the Multiple Sclerosis Quality of Life-54 (MSQoL-54) questionnaire.MethodsThis cross-sectional study was conducted on a group of patients with MS (n=382) referring to Shahid Kazemi Pharmacy, based in the city of Tehran, Iran, as a national pharmacy providing specialized pharmaceutical care to these individuals from February 2019 to March 2020 via the implementation of the MSQoL-54 questionnaire. ResultsA total number of 382 patients with MS participated in this study, including 89 (23.3%) men and 293 (76.7%) women, aged 40±10.9 years old (range: 18-84 years old). The overall score of the MSQoL-54 questionnaire was also by 41.58, and that was 69.60 and 62.99 from 100 for PHC and MHC, respectively. Conclusions The study results demonstrated that advanced age, longer disease duration, and lower levels of education were significantly associated with lower QoL. Trial registration IR.SBMU.PHARMACY.REC.1398.240.


1970 ◽  
Vol 6 (4) ◽  
pp. 26-30
Author(s):  
Jai Kirshin ◽  
Sameena Afghan ◽  
Aqeela Ayub ◽  
Kishor Shah ◽  
Maqbool Hussain

BACKGROUND: Measles is highly endemic disease in Pakistan that can be prevented by vaccinating the child.Patients with rash and fever are the major syptoms of this infection. The aim of this study was to find the associationof clinical and serological outcome of measles and rubella with demographic profiles in patients hospitalised withclinical suspicion of these conditions. METHODS: A descriptive cross sectional study was conducted in children hospital of PIMS Islamabad where allchildren presenting with maculopapular rash in outdoor patient, indoor patient and accident and emergencydepartment were enrolled. The study duration was one year or the completion of required sample size. A total of 73children who fulfilled the inclusion criteria were enrolled in this study. A purposive sampling technique was used toselect cases. Data was collected through a structured proforma especially designed for this study. Permission wastaken from the Hospital Ethical Committee before the commencement of the study. A written consent was also takenfrom the parents of children prior to conduct the study. RESULTS: All the children in this study was 46.5 (± 40.1) months of age, the mean (SD) age was 4 years and 10months (± 3 years and 4 months). The median age of all children was 24 months (2 years). The youngest child was 7months old while the eldest child was 12 years (144 months) of age. Out of 73 children enrolled in the current studywho presented with maculopapular rash and their serological outcome was assessed, 50 (68.5 percent) were boyswhereas 23 (31.5 percent) were girls. Koplik's spots were present among 56 (76.7 percent) children whereas 17(23.3 percent) did not have Koplik's spots at the time of enrolment. lymphadenopathy was assessed in 35 (47.9percent) children while 38 (52.1 percent) did not have lymphadenopathy at the time of enrolment. CONCLUSION: Study concluded that a higher proportion of children presenting with maculopapular rash werediagnosed to have measles on the basis of serology.


Author(s):  
Zahra Vakili ◽  
Fatemeh Heydarpour ◽  
Foroud Shahbazi

Background: Direct oral anticoagulants (DOACs) are increasingly used due to fewer side effects, predictable pharmacokinetics, lower potential for drug interactions. Different levels of awareness among health care professionals have been reported. Methods: The main objectives of this study were to investigate the knowledge and attitude of pharmacists about direct oral anticoagulants. The present study was a descriptive cross-sectional study performed in Kermanshah province, Iran. The validated researcher-made questionnaire included questions about demographic characteristics and specialized questions that assessed the knowledge and attitude of pharmacists towards new oral anticoagulants.             Results: Out of 126 pharmacists participating in this study, 67 (53.2%) were male. The mean scores of knowledges and attitude in pharmacists were 64.94±5.84 and 28.62±3.98, respectively. The most common oral anticoagulant with a direct effect dispensed by pharmacists was rivaroxaban (77.4%). There was also a significant relationship between pharmacists' attitudes and their place of activity (P = 0.024). Conclusion: The results of this study showed that pharmacists had an acceptable knowledge and low attitude about DOACs.


New Medicine ◽  
2020 ◽  
Vol 24 (3) ◽  
Author(s):  
Anna Turska-Szybka ◽  
Paula Piekoszewska-Ziętek ◽  
Dariusz Gozdowski ◽  
Dorota Olczak-Kowalczyk

Introduction. Oral lesions in newborns and infants represent a wide range of diseases often creating apprehension and anxiety among parents. Aim. We aimed to assess the type, prevalence and associated factors of oral lesions in newborns and infants. Material and methods. Participants were recruited during a two-year cross-sectional study among children who had their first teething assessed. The mothers answered medical history questions and the children underwent a clinical examination by paediatric dentists after training, calibration, and pilot study. Results. Two hundred and forty-eight children aged up to 12 months took part in the study. The mean number of teeth (SD) was 1.96 (2.55). 1.25% of children had natal teeth. Dental caries was observed in 3.2% children; traumatic dental injuries caused by falling in 7%; enamel hypoplasia in 1.9%, and mucosal lesions in 19.8% (Bohn’s nodules, mucocele, candidiasis). Conclusions. Oral lesions in infants may involve teething, teeth and oral mucosa. One child out of five children has mucosal lesions, most often Bohn’s nodules or candidiasis. There is a significant correlation between the prevalence of natal/neonatal teeth and of Bohn’s nodules.


2014 ◽  
Vol 21 (03) ◽  
pp. 556-558
Author(s):  
Ejaz Hussain Siddiqui ◽  
Saad Siddiqui ◽  
Romana Ayub ◽  
Noreen Shah

Objectives: To assess common presenting features of children with abdominalpain and to determine role of High frequency & Doppler Ultrasound in evaluation of thesepatients. Material and Methods: This is a cross sectional study conducted from August 2012 toDecember 2012. Data from patients presenting for evaluation of abdominal pain was analyzed forpresenting complaints and ultrasound findings according to objectives of the study. Results: Intotal 262 cases were included in the study. The mean age of patients was 6.3 years with a male tofemale ratio of 1.47:1. Dysuria followed by Diarrhoea and vomiting were most commonassociated complaints, Urological pathologies were most common ultrasound findings uponevaluation of patients. Conclusions: Abdominal pain is a frequent presenting feature inpeadiatric population, Urological pathologies were most common examination findings.Ultrasound is a useful and safe modality in evaluation of abdominal pain in children.


F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1973
Author(s):  
Khalid Obiad Mohsin Almohammadawi ◽  
Haider Saadoon Qasim Alhilfi ◽  
Rafid Adil Abood Alkhalidy

Background: Migraine is the most common primary headache. This study aimed to describe clinical observations about migraine in outpatients in Iraq, including migraine types and subtypes, duration and frequency of acute attacks, severity, disability, effects on the quality of life, and complications. Methods: This is an outpatient-based prospective cross-sectional study, conducted in the Misan province, Iraq over nine years, and included 1412 patients aged 12 to 50 years. The data was collected from clinical records of patients who attended outpatient clinics. Results: The study included 1100 women (77.9%) and 312 men (22.1%); the women/men ratio being 3.5:1. The median age and standard deviation (SD) was 21 ± 5.42 years. The mean age at first attack of migraine was 17 ± 4.91 years. Migraine without aura was the most common type, accounting for 68% of the cases. The mean frequency of the attacks was (2 ± 4.63) days/month. In general, acute attacks were moderate to severe. Conclusions: In our study, we observed that migraine causes a headache resulting in episodes of temporary functional disability and women suffered more than men (ratio of 3.5:1). The mean age at first attack was a young age, and a family history of migraine highly altered distribution. Migraine without aura was the most common type, and symptoms including nausea and vomiting and photophobia were experienced by patients, which were used to diagnose migraines. Experienced aura was the most common migraine with aura, but also aura without a headache and aura with migraine were prevalent; therefore, it is important to differentiate between migraine subtypes. Visual aura was the most common aura, while motor symptoms were very rare. Chronic persistent headaches were a common complication recorded. These features provide evidence for the creation of screening tools in migraine prevention migraine.


2022 ◽  
Author(s):  
Hossein Mozhdehipanah ◽  
Ali Emami ◽  
Shima Mohammadhoseini Targhi ◽  
Fatemeh Kazemi ◽  
Ali Sarbazi-Golezari ◽  
...  

Abstract Background: Multiple sclerosis (MS) is a key neurogenic cause of disability among young populations. Assessing the parameters affecting MS severity is vital to reduce the disease burden. the objective of this study is to determine the relationship between socioeconomic status (SES) and MS severity among Iranian young adults.Methods: A descriptive-analytical cross-sectional study was conducted by 180 patients (142 females and 38 males) with MS selected by a non-probability and consecutive sampling was conducted during September 2018-2019. The socio-demographic and primary clinical data were collected by a self-developed questionnaire and face-to-face interviews, respectively. The expanded disability status scale (EDSS) was used to assess the physical disability degree and the overall neurological function of patients.Results: The mean age of patients and MS onset was 27.54 and 35.58 years, respectively. The majority of patients were married (68.3%) while were living in cities (74.4%). The mean values of unemployment, homeownership, and monthly income were determined to be 54.4%, 71.7%, and 11,078,330 IRR, respectively. The mean EDSS was 2.80±1.79 points. A weak positive correlation between EDSS and patients' age (P = 0.001, r = 0.246) and number of children (P = 0.001, r = 0.250) was found. There was no significant difference between EDSS and SES factors (i.e., disease onset age, treatment cost, and monthly income).Conclusions: As SES was not related to the MS severity, there is no need to take special treatment measures in patients with poor SES.


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