scholarly journals Social and Housing Determinants of Dengue and Chikungunya in Indian Adults Aged 45 and Above: Analysis of a Nationally Representative Survey (2017-18)

2021 ◽  
Author(s):  
Winnie Paulson ◽  
Karuppusamy Balasubramani ◽  
Rashi Dixit ◽  
Savitha Chellappan ◽  
Sujit Kumar Behera ◽  
...  
Keyword(s):  
Control Strategies ◽  
Water Source ◽  
Health Concern ◽  
Wealth Status ◽  
Vector Borne Diseases ◽  
Primary Schooling ◽  
Vector Borne ◽  
Nationally Representative ◽  
The Difference ◽  
And Control

Abstract BackgroundDengue and chikungunya (CHIKV) are the two major vector-borne diseases of serious public health concern in India. Studies on socio-economic and housing determinants of dengue and CHIKV at a pan-India level are lacking. Here, we took advantage of the recently carried out Longitudinal Ageing Study in India (LASI) carried across all the States and Union Territories of India to study the social determinants of dengue and CHIKV in India.MethodsLASI-1 (2017-2018) data on the self-reported period prevalence of dengue and CHIKV from 70,865 respondents aged ≥45 years were used for this analysis. The State-wise distribution of dengue and CHIKV was mapped. Prevalence was estimated for each study variable, and the difference was compared using the χ2 test. The adjusted odds ratios (AOR) of the socio-economic and housing variables for dengue and CHIKV were calculated using a multiple logistic regression model.ResultsUrban residence is the major socio-economic determinant of dengue and CHIKV (dengue: AOR: 1.57, 95% CI: 1.17-2.10; CHIKV: AOR 1.56, 95% CI: 1.20-2.02). Wealth status (richest) and less than primary schooling are associated with dengue and CHIKV prevalence. In addition to these factors, social group (scheduled and forward castes) is also associated with CHIKV prevalence. Water-source outside the dwelling (AOR: 1.20, 95% CI: 0.96-1.50), pucca or semi- pucca house type are also associated with increased odds of CHIKV. ConclusionsDespite the limitation that the data is only from adults ≥ 45, this analysis provides important insights into the socio-economic and housing variables that increase the odds of dengue and CHIKV in India. Understanding these determinants may assist in the national planning of prevention and control strategies for dengue and CHIKV.

scholarly journals Wolbachia: endosymbiont of onchocercid nematodes and their vectors

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Ranju Ravindran Santhakumari Manoj ◽  
Maria Stefania Latrofa ◽  
Sara Epis ◽  
Domenico Otranto
Keyword(s):  
Control Strategies ◽  
Molecular Data ◽  
Scientific Data ◽  
Growth And Survival ◽  
Vector Borne Diseases ◽  
Wide Range ◽  
Veterinary Importance ◽  
Wolbachia Endosymbiont ◽  
Vector Borne ◽  
And Control

Abstract Background Wolbachia is an obligate intracellular maternally transmitted, gram-negative bacterium which forms a spectrum of endosymbiotic relationships from parasitism to obligatory mutualism in a wide range of arthropods and onchocercid nematodes, respectively. In arthropods Wolbachia produces reproductive manipulations such as male killing, feminization, parthenogenesis and cytoplasmic incompatibility for its propagation and provides an additional fitness benefit for the host to protect against pathogens, whilst in onchocercid nematodes, apart from the mutual metabolic dependence, this bacterium is involved in moulting, embryogenesis, growth and survival of the host. Methods This review details the molecular data of Wolbachia and its effect on host biology, immunity, ecology and evolution, reproduction, endosymbiont-based treatment and control strategies exploited for filariasis. Relevant peer-reviewed scientic papers available in various authenticated scientific data bases were considered while writing the review. Conclusions The information presented provides an overview on Wolbachia biology and its use in the control and/or treatment of vectors, onchocercid nematodes and viral diseases of medical and veterinary importance. This offers the development of new approaches for the control of a variety of vector-borne diseases. Graphic Abstract

scholarly journals Epidemiological situations and control strategies of vector-borne diseases in Nepal during 1998–2016

2019 ◽  
Vol 33 (6) ◽  
pp. 478-493
Author(s):  
Shanker Bahadur Shrestha ◽  
Uttam Raj Pyakurel ◽  
Mukti Khanal ◽  
Murari Upadhyay ◽  
Kesara Na-Bangchang ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Dengue Fever ◽  
Dengue Hemorrhagic Fever ◽  
Control Strategies ◽  
Hemorrhagic Fever ◽  
Content Type ◽  
Vector Borne Diseases ◽  
Kala Azar ◽  
Vector Borne ◽  
And Control

Purpose The purpose of this paper is to investigate epidemiology and control strategies of the four priority vector-borne diseases (VBDs) in Nepal, i.e. malaria, Kala-azar (visceral leishmaniasis), lymphatic filariasis (LF) and dengue fever/dengue hemorrhagic fever. Design/methodology/approach The study was a retrospective design to collect data during 1998–2016 from VBDs endemic districts of Nepal. All data were reviewed and epidemiological information of the four VBDs were analyzed. Findings The number of malaria cases during 1998–2016 of the 13 affected districts was declined from 8,498 to 991 cases with no record of deaths since 2012. The number of cases and deaths in the 12 kala-azar (visceral leishmaniasis) affected districts in 1998 was 1,409 and 42 cases, respectively, but was dramatically decreased in 2016 to 213 and 2 cases, respectively. LF cases of the 61 affected districts in 2011, 2014 and 2016 were 28,855, 30,000 and 33,517 cases, respectively. In total, 25 districts achieved elimination target and the remaining are expected to complete the needful cycles by 2018. Dengue incidence of the 31 affected districts during 2006–2015 was under controlled with reported cases of 642, 356 and 136 cases in 2013, 2014 and 2015, respectively, and only one death in 2015. Implementation of control strategies particularly disease management and community peoples’ awareness significantly reduced the cases and deaths of the target VBDs. Practical implications The results of this study clearly suggest that the current control strategies have been worked effectively. However, in particular of the VBDs, health education in communities in the endemic areas should be adopted for better community participation in the context of the primary health care approach and increase the effectiveness of disease control. Originality/value VBDs, i.e., malaria, kala-azar (visceral leishmaniasis), LF and dengue fever/dengue hemorrhagic fever, are major causes of morbidity and mortality in the least developed countries which include Nepal. Globalization of travel and trading, unplanned urbanization, environmental and climate change are having a significant impact on disease transmission. Therefore, the Ministry of Health of Nepal had brought some changes in strategies based on activities for disease control, vector control, preventive and preparedness for outbreak response. Consequently, the cases and deaths due to malaria, kala-azar (visceral leishmaniasis), lymphatic filaiasis and dengue fever/dengue hemorrhagic fever have been brought down markedly.

scholarly journals Trends of HIV/AIDS Highlighted the Progresses and Challenges in Prevention and Control From 1990 to 2019

2021 ◽  
Author(s):  
Zejin Ou ◽  
Huan He ◽  
Danfeng Yu ◽  
Yongzhi Li ◽  
Yuanhao Liang ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Control Strategies ◽  
Health Concern ◽  
Effective Prevention ◽  
Global Trends ◽  
Life Years ◽  
Disease Study ◽  
And Control ◽  
Increasing Trends ◽  
Hiv Aids

Abstract Background HIV/AIDS is a critical public health concern worldwide. This article aimed to demonstrate th trends of HIV/AIDS burden from 1990 to 2019.Methods Data was extracted from the Global Burden of Disease study (GBDs) 2019. Estimated annual percentage change (EAPC) and age-standardized rate (ASR) were estimated to quantify the trends at global, regional and national levels.Results During the period 1990-2004, the trend in incidence of HIV/AIDS was stable globally. Whereas the trends in prevalence, death and disability-adjusted life years (DALYs) had pronounced increasing trends, with the respective EAPCs were 7.47 (95%confidence interval [CI]: 5.84 to 9.12), 10.85(95%CI: 8.90 to 12.84), and 10.40(95%CI: 8.47 to 12.36). Meanwhile, the pronounced increasing trends were seen in low-resource settings, particularly that of death in Oceania and South Asia, in which the respective EAPCs were 44.76 (95%CI: 40.81 to 48.82) and 40.82 (95%CI: 34.31 to 47.64). However, the global trends in incidence, death and DALYs of HIV/AIDS pronouncedly decreased from 2005 to 2019, with the respective EAPCs were −2.68(95%CI: −2.82 to −2.53), −6.73(95%CI: −6.98 to −6.47) and −6.75(95%CI: −6.95 to −6.54). Whereas prevalence showed increasing trend (EAPC: 0.71, 95%CI: 0.54 to 0.87). Decreasing trends of HIV/AIDS were observed in most regions and countries, particularly that of death and DALYs in Burundi respectively were −15.28 (95%CI: −16.08 to −14.47) and −15.07 (95%CI: −15.79 to −14.33). Conclusions Decreasing trends of HIV/AIDS were observed worldwide over the past 15 years. However, HIV/AIDS remains one of the most critical causes of health loss worldwide, which emphasized the effective prevention and control strategies.

Vector-borne diseases in Iran: epidemiology and key challenges

2021 ◽  
Vol 16 (1) ◽  
pp. 51-69
Author(s):  
Najmeh Parhizgari ◽  
Norair Piazak ◽  
Ehsan Mostafavi
Keyword(s):  
Q Fever ◽  
Hemorrhagic Fever ◽  
Health Concern ◽  
Current Status ◽  
Vector Borne Diseases ◽  
High Prevalence ◽  
Dispersion Patterns ◽  
Monitoring And Surveillance ◽  
Vector Borne ◽  
Review Study

Vector-borne diseases have become a global health concern in recent decades as a result of global warming, globalization, growth in international trade and travel, use of insecticide and drug resistance. This review study addressed the key vector-borne diseases and their current status in Iran to emphasize the requirements for further research on vector-borne diseases. The dispersion patterns of these diseases differ in various regions. Some of them such as Crimean–Congo hemorrhagic fever, and Q fever are distributed all across Iran, whereas some others such as plague, leishmaniasis, tularemia, and malaria are restricted to specific areas. The high prevalence of vectors throughout the country necessitates enhancing the monitoring and surveillance of emerging and reemerging vector-borne diseases and their potential vectors.

scholarly journals Vaccine and Therapeutic Options To Control Chikungunya Virus

2017 ◽  
Vol 31 (1) ◽  
Author(s):  
Ann M. Powers
Keyword(s):  
Vector Control ◽  
Future Development ◽  
Chikungunya Virus ◽  
Therapeutic Options ◽  
Protective Measures ◽  
Vector Borne Diseases ◽  
Advantages And Disadvantages ◽  
Vector Borne ◽  
And Control ◽  
Integrated Vector Control

SUMMARYBeginning in 2004, chikungunya virus (CHIKV) went from an endemic pathogen limited to Africa and Asia that caused periodic outbreaks to a global pathogen. Given that outbreaks caused by CHIKV have continued and expanded, serious consideration must be given to identifying potential options for vaccines and therapeutics. Currently, there are no licensed products in this realm, and control relies completely on the use of personal protective measures and integrated vector control, which are only minimally effective. Therefore, it is prudent to urgently examine further possibilities for control. Vaccines have been shown to be highly effective against vector-borne diseases. However, as CHIKV is known to rapidly spread and generate high attack rates, therapeutics would also be highly valuable. Several candidates are currently being developed; this review describes the multiple options under consideration for future development and assesses their relative advantages and disadvantages.

Assessing the Impact of Temperature Change on the Effectiveness of Insecticide-Treated Nets

2011 ◽  
Vol 3 (3) ◽  
pp. 35-48 ◽  
Author(s):  
Gregory J. Davis
Keyword(s):  
Control Strategies ◽  
Global Climate ◽  
Financial Burden ◽  
Insecticide Treated Nets ◽  
Policy Makers ◽  
Agent Based ◽  
Mosquito Abundance ◽  
Vector Borne ◽  
And Control ◽  
The Impact

Malaria is a vector-borne illness affecting millions of lives annually and imposes a heavy financial burden felt worldwide. Moreover, there is growing concern that global climate change, in particular, rising temperature, will increase this burden. As such, policy makers are in need of tools capable of informing them about the potential strengths and weaknesses of intervention and control strategies. A previously developed agent-based model of the Anopheles gambiae mosquito is extended, one of the primary vectors of malaria, to investigate how changes in temperature influence the dynamics of malaria transmission and the effectiveness of a common malaria intervention: insecticide-treated nets (ITNs). Results from the simulations suggest two important findings. Consistent with previous studies, an increase in mosquito abundance as temperature increases is observed. However, the increase in mosquito abundance reduces the effectiveness of ITNs at a given coverage level. The implications and limitations of these findings are discussed.

‘Swimming mosquitoes’: a key stepping stone to prevent Dengue, Zika and Chikungunya: an educative experience in Colima, Mexico

2019 ◽  
Vol 34 (4) ◽  
pp. 389-399 ◽  
Author(s):  
Paula Medone ◽  
Carlos M Hern�ndez-Su�rez
Keyword(s):  
Risk Perception ◽  
Control Strategies ◽  
Social Representations ◽  
Adult Mosquito ◽  
Breeding Sites ◽  
Stepping Stone ◽  
Public Issues ◽  
Vector Borne Diseases ◽  
The People ◽  
Vector Borne

Abstract Dengue, Zika and Chikungunya arboviruses (DZC), mainly transmitted by mosquito Aedes aegypti, are global health public issues affecting 390 million people each year. In most endemic countries, vector control strategies have been focused on reducing breeding sites and adult mosquito populations. Most health communication strategies have pointed out adult mosquito as the main responsible of the transmission, persuading people to eliminate domestic containers. However, it is not clear how should people understand the relationship between adult mosquitoes and water domestic containers. So, the main goal of the present study was to assess the people understanding of this relationship. Results showed that most people associate adult mosquitoes with DZC, but only few could associate swimming larvae with mosquitoes. The unawareness of larva presence leads to an underestimation of risk perception about DZC transmission. In this context, we consider that educative interventions for health promotion, based on meaningful knowledge and social representations arise as long-term strategies to control transmission of vector-borne diseases. Here, we propose innovative health strategies focused on increase the risk perception about swimming larvae, considering social representations, which may be a key stepping stone to increase people adherence to massive campaigns and reducing DZC burden.

scholarly journals Mapping Environmental Suitability of Scrub Typhus in Nepal Using MaxEnt and Random Forest Models

2019 ◽  
Vol 16 (23) ◽  
pp. 4845
Author(s):  
Bipin Acharya ◽  
Wei Chen ◽  
Zengliang Ruan ◽  
Gobind Pant ◽  
Yin Yang ◽  
...  
Keyword(s):  
Vegetation Index ◽  
Normalized Difference Vegetation Index ◽  
Agricultural Land ◽  
Scrub Typhus ◽  
Control Strategies ◽  
National Level ◽  
Spatial Prediction ◽  
Health Concern ◽  
Environmental Suitability ◽  
And Control

Being a globally emerging mite-borne zoonotic disease, scrub typhus is a serious public health concern in Nepal. Mapping environmental suitability and quantifying the human population under risk of the disease is important for prevention and control efforts. In this study, we model and map the environmental suitability of scrub typhus using the ecological niche approach, machine learning modeling techniques, and report locations of scrub typhus along with several climatic, topographic, Normalized Difference Vegetation Index (NDVI), and proximity explanatory variables and estimated population under the risk of disease at a national level. Both MaxEnt and RF technique results reveal robust predictive power with test The area under curve (AUC) and true skill statistics (TSS) of above 0.8 and 0.6, respectively. Spatial prediction reveals that environmentally suitable areas of scrub typhus are widely distributed across the country particularly in the low-land Tarai and less elevated river valleys. We found that areas close to agricultural land with gentle slopes have higher suitability of scrub typhus occurrence. Despite several speculations on the association between scrub typhus and proximity to earthquake epicenters, we did not find a significant role of proximity to earthquake epicenters in the distribution of scrub typhus in Nepal. About 43% of the population living in highly suitable areas for scrub typhus are at higher risk of infection, followed by 29% living in suitable areas of moderate-risk, and about 22% living in moderately suitable areas of lower risk. These findings could be useful in selecting priority areas for surveillance and control strategies effectively.

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