Knowledge, Practice, and Attitude of patients and physicians towards insulin therapy in Type 2 DM: a cross sectional study in TASH patients and Physician from various universities in Ethiopia

Author(s):  
Biniyam Woya Sheno ◽  
Ahmed Reja

Abstract Background As type 2 DM is a growing health problem worldwide early treatment and intensification of therapy will decrease the vascular complications as evidenced by large trials. Insulin therapy is delayed in this group of patients and multiple physician and patient factors are mentioned in different settings. Methods This study is a cross-sectional, quantitative descriptive study conducted on 221patients at TASH endocrine clinic and 122 physicians working at TASH, residents visiting for detachment, and Yekatit 12 hospital. Conducted on Jul 1- Sep 30, 2020, G.C Result 76% of physicians think taking insulin at the prescribed time is difficult while only 31.5% of patients think it’s difficult. Hypoglycemia is one of the most fearful parts of having diabetes for 81.1% of patients on Insulin therapy. 87% of physicians and76.6% of patients think insulin-treated diabetes controls life while. 56% of patients therapy know nothing about insulin therapy. 23% of patients said they will not accept insulin therapy the top reason being they will be afraid of insulin injection because they think it will be painful. Conclusion Physicians tend to overestimate the difficulty of insulin injection preparation and dose adjustment fears the risk of hypoglycemia when starting insulin therapy. More than half of our patients not on insulin therapy know nothing about insulin therapy which we have to improve. Even if patients not on insulin therapy overestimate insulin needle phobia and injection pain those who are already on insulin disagree with them.

Author(s):  
Andi Syamsudduha ◽  
S. V Sembiring ◽  
R DN Pakasi

Diabetic patients can suffer from hipokalemia because of prolonged osmotic diuretic and management diabetic mellitus with insulinif does not associate with kalium intake. The aimed of this study was to evaluate kalium serum level on type 2 DM, and comparisonof kalium serum level on type 2 DM patients with or without insulin therapy. A cross-sectional study was done on 33 patiens type 2diabetic mellitus that admission on Stella Maris Hospital who examined kalium serum level. The data were colected from Medical Recordperiode January to December 2007. Data were analyzed with Fisher Exact test using SPSS versi 11.5. From 33 samples found normalkalium level 9 samples (27.3%) and decreased 6 samples (18.2%) and without insulin therapy found decresed 3 samples (9.1%) andnormal Kalium level 15 samples (45.5%). Comparison of Kalium serum level of type 2 DM patiens with or without insulin therapydid not statistically significant with P = 0.135. Kalium serum level of type 2 DM patiens with or without insulin therapy commonly inreference value.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Randa I. Farah ◽  
Mohammed Q. Al-Sabbagh ◽  
Munther S. Momani ◽  
Asma Albtoosh ◽  
Majd Arabiat ◽  
...  

Abstract Aim Diabetic kidney disease (DKD) is a major long-term complication of diabetes mellitus (DM). Given the paucity of data on DKD in Jordan, we aimed to evaluate the prevalence, characteristics and correlates of DKD in Jordanian patients with type 2 DM. Methods This cross-sectional study included 1398 adult patients with type 2 DM who sought medical advice in the endocrinology clinic between March and September 2019. Demographic, clinical and laboratory data were reviewed. DKD was defined as reduced eGFR, and/or albuminuria. Three regression models were constructed to identify factors associated with CKD stages, albuminuria and DKD. Results Overall, 701 (50.14%) patients had DKD, with a median age of 59.71 ± 11.36  years. Older age, high triglycerides, and low high-density lipoprotein were associated with DKD (multivariable odds ratio [OR]: 1.02, 95% confidence interval [CI]: 1.01–1.03, p < 0.01; OR: 1.1, 95% CI: 1.01–1.2; and OR: 0.98, 95% CI: 0.97–0.99, p < 0.01 respectively). Metformin and renin-angiotensin system blockers were negatively associated with albuminuria and chronic kidney disease stages (p < 0.01). Conclusion Our study demonstrated that approximately one half of patients with type 2 DM had DKD. Further studies are necessary to understand this high prevalence and the underlying factors. Future research are needed to assess implementing targeted community-based intervention.


2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Mustapha Zainab Abubakar ◽  
Kabiru Abdulsalam ◽  
Isah A. Yahaya

Diabetes mellitus (DM) and thyroid disease are the two most common endocrine disorders in the general population. Several Studies have shown that thyroid dysfunction is common in patients with DM, and thyroid dysfunction have been found to have a considerable impact on the glycaemic control and often increases the risk of development of long-term complications in patients with diabetes mellitus. This study determined the prevalence of thyroid dysfunction in patients with type 2 DM in Kano, North-Western Nigeria. The study was a descriptive cross-sectional study conducted on 250 participants made up of 130 patients with type 2 DM and 120 apparently healthy non-diabetic controls. Questionnaires were used to collect information on bio data, medical history, duration of diagnosis of diabetes and type of treatment. Also, blood samples of the participants were collected and analyzed for fasting plasma glucose, fT3, fT4, and TSH. The results were interpreted using American Thyroid Associations’ criteria and the data was analyzed using the statistical software package, STATA version 20. Two hundred and thirty-four (93.6%) of the participants were euthyroid while sixteen (6.4%) were found to have various forms of thyroid dysfunction. The prevalence of thyroid dysfunction was 10% and 2.5% among type 2 diabetics and controls respectively. Among the type 2 DM patients with thyroid dysfunction, 38.5% had hypothyroidism. Thyroid dysfunction was found to be commoner among type 2 DM patients than non-diabetic individuals with hypothyroidism being the commonest disorder.


2020 ◽  
Vol 6 (1) ◽  
pp. 39-45
Author(s):  
Reny Sulistyowati ◽  
Agnes Dewi Astuti

The level of adherence usually decreases in patients with chronic conditions compared to acute conditions; this is related to the long-term nature of chronic disease due to the most rapid decrease in adherence after the first 6 months of therapy. The decline in compliance not only resulted in poor health outcomes but also had a significant impact on health costs. The purpose of this study was to determine family support for medication adherence in type 2 DM patients. This study used descriptive correlational using a cross-sectional study approach of 100 respondents. Patient demographic data and family support were obtained using a questionnaire while the level of compliance used Morisky Medication Adherence Scales. The results show that there is a relationship between family support and medication adherence in patients with type 2 diabetes, which is viewed from 4 dimensions: appreciation support, emotional support, information support, and instrumental support. Support from family can improve medication adherence in type 2 DM patients.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Tatiana de Paula ◽  
Mauren de Freitas ◽  
Vanessa Lopes ◽  
Maria Elisa Miller ◽  
Karen Araujo ◽  
...  

Abstract Objectives The aim of the study was to establish the prevalence of sarcopenia and associated factors in elderly with type 2 diabetes (DM) in southern Brazil. Methods A cross-sectional study was performed in 240 patients with type 2 DM. The diagnosis of sarcopenia was performed according to EWGSOP criteria. Muscle mass was calculated by skeletal muscle mass index (appendicular skeletal muscle mass/height² - Inbody® bioimpendance). Muscle strength was assessed by manual grip strength (Jamar® dynamometer) and physical performance was assessed by the sit and lift test. Patients with type 2 DM with age ≥60 years and with the ability to ambulate were selected. Patients with recent cardiovascular events, serum creatinine >2.0 mg/dl, use of corticosteroids and BMI >40 kg/m² were excluded. The sample size was 240 patients based on meta-analysis who found 17% sarcopenia in elderly patients without DM. Results We included 240 patients aged 68.4 ± 5.5 years, 53.2% were women and the duration of DM was 15 (8–22) years, the BMI was 29.4 ± 4.4 kg/m². The prevalence of sarcopenia was 21% and men had more sarcopenia (75%). Patients with sarcopenia walk less [3541 (2227–4574) vs. 4521 (3037–5678) steps, P = 0.013], drink more alcohol [21 (56.8%) vs. 71 (31.8%); P < 0.034] and have lower total cholesterol levels [146 ± 41 Vs. 168 ± 43; P = 0.007] than the group without sarcopenia. In multivariate logistic regression models, walking < 3760 steps [OR = 2868; CI 95% 1.331–6.181] and male [OR = 5285; CI 95% 2261–12,350], were associated with sarcopenia. Conclusions The prevalence of sarcopenia was 21%, higher than in patients without diabetes (17%). In this group of patients, lower physical activity, and male sex were associated with sarcopenia. Funding Sources FIPE n. 160467; CAPES.


2019 ◽  
Author(s):  
Adeladlew Kassie Netere ◽  
Eyayaw Ashete ◽  
Eyob Alemayehu Gebreyohannes ◽  
Sewunet Admasu Belachew

Abstract Background: Diabetes mellitus is a group of metabolic disorders and resulting from deficits in insulin secretion, insulin action, or both. Insulin therapy is primarily required to attain the recommended goal of blood sugar. The primary aim of this study was to evaluate the knowledge, skills and practices of insulin storage and injection technique of patients. Methods : An interview based cross-sectional study was conducted in conveniently selected participants in Northwest Ethiopian primary hospitals from March, 1, 2019 to May, 30, 2019. Knowledge and practice were measured by administering structured questionnaire with a Likert scale of 1–5 through face-to-face interviews and skills were assessed by five observational (demonstration) techniques from a total of 166 clients. Results: Of the total 166 participants, 54.8% were males and the mean age was 38.46±13.8 years . The overall knowledge (65.4%.) and practice (53.89%) rate on insulin storage and handling techniques were showed moderate knowledge and fair practices. About 94.6% of participants correctly shown insulin injection sites. One-way ANOVA showed that the level of education [F (3, 162) = 7.283, p<0.001], ways of instruction of insulin injection [F (2, 163) =3.32, p = 0.039], insulin therapy duration [F (3,162) = 3.59, p= 0.015] and assessing insulin storage [F (2,163) = 4.45, p = 0.013] had a significant effect on level of knowledge. Similarly, knowledge level [F (2,163) = 14.17, p < 0.001], educational status [F (3,162) = 10.57, p <0.001], occupation type [F (4,161) = 5.43, p <0.001], time since insulin therapy [F (3, 162) = 5.46, p = 0.001] and diagnosis [F (3,162) = 3.36, p= 0.02] had a significant effect on patients’ insulin storage and administration practices. Conclusion: Patient had marginal knowledge and practices on insulin storage and administration techniques. The patients’ skills on the important and critical steps of administrations are poor. The engagements of healthcare professionals and stakeholders should be in developments of instructions and guidelines are very crucial in addition to focusing on educating and changing their wrong perceptions, believes and attitudes towards storage and administering techniques.


2021 ◽  
Vol 14 (01) ◽  
pp. 379-383
Author(s):  
Akshai Lekshmi P ◽  
T Srimathi ◽  
V S Anandarani

Diabetes mellitus [DM] is a major disease worldwide with increasing prevalence. Its etiologic heterogeneity comprising genetic predisposition and environmental factors may provide a characteristic feature among the population helpful for the early diagnosis. This study aims to evaluate the palmar dermatoglyphic patterns in DM patients. This case controlled cross-sectional study included 100 type 2 DM patients in group A and 100 healthy subjects in group B. Each group has equal gender distribution. The palmar dermatoglyphics were evaluated quantitatively using standard methods. Student’s t-test and Chi-square test was used to determine the level of significance. The palmar triradius number varied significantly (Pd”0.0001). The angle of palm variations were statistically insignificant between groups, but TAD angle showed significant gender variations in group A patients (Pd”0.0001). The variation in palmar triradius revealed in this study may help in early diagnosis of type 2 DM patients and also may provide a scope for further studies with larger sample size.


2019 ◽  
Vol 1 (1) ◽  
pp. 35-44
Author(s):  
Indah Lestari ◽  
Dzul Rizka ◽  
Prema Hapsari ◽  
Pratiwi L Basri ◽  
Nur Hidayah

Background: The prevalence of diabetes mellitus in the world has increased which is certainly accompanied by a rapid increase in the incidence of its chronic complications like kidney disorders. Insulin resistance, the patophysiology of diabetes mellitus, also associated with obesity, which both are the main risk factors for cardiovascular events. Obesity also known as a risk factor for kidney disease that proved by the presence of proteinuria in obesity patients. Objective: To determine the correlation of obesity with occurrence of proteinuria in patients with type 2 DM in internal medicine polyclinic Ibnu Sina Hospital Makassar. Method: A cross sectional study on 32 type 2 DM patients at Ibnu Sina Hospital as measured by body weight, height and waist circumference. Urinalysis examination is also performed at that time. Results: In this study, there were 4 patients (12,5%) patients with proteinuria (+), 1 patient (3.1%) with proteinuria (++), 2 patients (6.3%) with proteinuria (+++) and 1 patient (3.1%) with proteinuria (++++). According to BMI, we found that 17 patients (53.1%) were overweight,  5 patients (15.6%) were class 1 obesity, no class 2 obesity patient, and 1 patients (3.1%) were class 3 obesity. In Waist circumference examination we found that  in normal waist circumference group there is 1 patient that did not has proteinuria while in the  abnormal waist circumference group, 8 patients out of 31 patients have proteinuria. After doing statistical analysis to assess the correlation of obesity with proteinuria obtained p value> 0.05. Similarly, the correlation analysis waist circumference with proteinuria obtained p value> 0.05. Conclusion: There is no correlation between obesity and proteinuria as well as waist circumference and proteinuria correlation in type 2 DM patients.


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