scholarly journals A Register-Based Study: Cough - A Frequent Phenomenon in the Adult Population

2021 ◽  
Author(s):  
Vibeke Backer ◽  
Andreas Porsborg ◽  
Victor Hansen ◽  
Tina Skjold ◽  
Johannes Martin Schmid ◽  
...  
Keyword(s):  
Chronic Cough ◽  
Adult Population ◽  
Challenge Test ◽  
Specific Treatment ◽  
Final Diagnosis ◽  
Patient Registry ◽  
Co Morbidity ◽  
National Patient ◽  
Icd 10 ◽  
Work Up

Abstract BackgroundChronic cough, more than 8 weeks, can either be without co-morbidity called unexplained chronic cough (UCC) or with co-morbidity called refractory chronic cough (RCC). Using datasets from the Danish National Prescription Registry (Prescription Registry) and Danish National Patient Registry (Patient Registry) we wanted to investigate the prevalence of cough in a Nationwide registry from both primary and secondary care setting.Material and MethodsInclusion criteria were patients 18-90 years with at least one final cough diagnosis (ICD-10 DR05/DR059) in Patient registry or patients who have redeemed ≥2 prescriptions for relevant cough-medication within a 90-day harvest in the Prescription registry from 2008-2017. To validate this study’s chosen proxy on chronic cough an analysis of the Patient registry sub-population with a contact of ≥8 weeks and then final diagnosis code DR05/DR059 was also performed. The population was divided into UCC and RCC.ResultsOf the 104.216 patients from the Prescription registry, 52.727 were classified as having UCC and 51.489 were classified with RCC. From the Patient registry 34.260 were included, of whom 12.278 had UCC and 21.982 had RCC. Cough were frequently found among females between 50 and 66 years. Spirometry was performed in 69% and 57%, X-ray in 73% and 58% and asthma challenge test performed in 13% and 5% (UCC and RCC, respectively). The frequency of co-morbidities such as heart failure, rheumatologic disease, pulmonary embolism, and diabetes was < 10%. The distribution of all the included variables of patients who have had attachment to the department for 8 weeks or more, was similar as in the main group, thus fewer.ConclusionMany patients suffer from chronic cough or cough requiring medications, with or without co-morbidity; frequently found among menopausal women. Most patients had a substantial work-up performed. The high frequency and the resources consuming work-up program call for systematic coding of disease, systematic patient evaluation and more specific treatment options.The study was accepted by the Danish Data Protection Agency (ID: no. P-2019-191)

scholarly journals Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry

2018 ◽  
Vol Volume 10 ◽  
pp. 1503-1508 ◽  
Author(s):  
Jacob Bodilsen ◽  
Michael Dalager-Pedersen ◽  
Nicolai Kjærgaard ◽  
Diederik van de Beek ◽  
Matthijs C Brouwer ◽  
...  
Keyword(s):  
Positive Predictive Value ◽  
Brain Abscess ◽  
Predictive Value ◽  
Patient Registry ◽  
National Patient Registry ◽  
Diagnosis Codes ◽  
Danish National Patient Registry ◽  
National Patient ◽  
Icd 10

Psychopathology of alcoholics during withdrawal and early abstinence

2000 ◽  
Vol 15 (8) ◽  
pp. 483-488 ◽  
Author(s):  
T Wetterling ◽  
K Junghanns
Keyword(s):  
Alcohol Withdrawal ◽  
Depressive Disorders ◽  
Specific Treatment ◽  
The Other ◽  
Depression And Anxiety ◽  
Symptom Profile ◽  
Co Morbidity ◽  
Icd 10 ◽  
Severe Psychopathology ◽  
The Impact

Epidemiologic surveys show a high lifetime co-morbidity with psychiatric disorders (e.g., depression and anxiety) in alcoholics. However, alcoholics frequently complained about psychopathologic symptoms, particularly during alcohol withdrawal. There is some evidence that symptomatology decreases spontaneously with prolonged abstinence. Thus, the question arises whether high levels of psychopathology could be accounted for by withdrawal effects. This study was aimed at examining the impact of the alcohol withdrawal severity (assessed by the AWS scale) on psychopathologic symptoms. The psychopathologic profile of 110 alcoholics as measured by the Symptom Checklist-90 revised (SCL-90-R) was compared to that of 253 patients with adjustment, anxiety or depressive disorders (according to ICD-10 criteria). No relationship between the severity of alcohol withdrawal and psychopathology could be found which might hint at two different neurobiological processes underlying these phenomena. The comparison with patients suffering from depression or anxiety disorders revealed that the global symptom severity of alcoholics undergoing withdrawal was similar, but recovery was achieved more rapidly than in the other groups. On the other hand, the self-rated psychopathologic symptom profile of alcoholics was rather similar to that of patients with adjustment disorders. While about one-quarter of the alcoholics reported severe psychopathology on admission, only about 10% showed symptomatology at discharge about three weeks later, predominantly depression or anxiety. These results underline the notion that much of the psychopathology described by alcoholics decreases within 2–3 weeks after withdrawal without specific treatment.

scholarly journals Evaluation of ICD-10 algorithms to identify hypopituitary patients in the Danish National Patient Registry

2017 ◽  
Vol Volume 9 ◽  
pp. 75-82 ◽  
Author(s):  
Agnethe Berglund ◽  
Morten Olsen ◽  
Marianne Andersen ◽  
Eigil Husted Nielsen ◽  
Ulla Feldt-Rasmussen ◽  
...  
Keyword(s):  
Patient Registry ◽  
National Patient Registry ◽  
Danish National Patient Registry ◽  
National Patient ◽  
Icd 10

Clinical and epidemiological characteristics of chickenpox in the adult population at the present stage

2020 ◽  
pp. 17-24
Author(s):  
Ekaterina Peredelskaya ◽  
Tatyana Safyanova ◽  
Mikhail Druchanov
Keyword(s):  
Health Care ◽  
Adult Population ◽  
Final Diagnosis ◽  
Health Care Institution ◽  
Federal State ◽  
Economic Damage ◽  
Clinical Hospital ◽  
Care Institution ◽  
High Level ◽  
Epidemiological Characteristics

Chickenpox is an urgent problem, as it is widely spread with a high level of morbidity and an increasing share in the structure of the General infectious pathology with significant economic damage. The aim of the study is to study the epidemiological and clinical features of chickenpox in adults hospitalized in Krai government-owned publicy funded health care institution «City clinical hospital No. 5, Barnaul» for the period 2008‑2018. Content analysis included statistical reporting forms No. 2 of Federal state statistical supervision «Data on infectious and parasitic diseases» in the city of Barnaul during the period 2008‑2018 of medical archival documents adult infectious Department Krai government-owned publicy funded health care institution «City clinical hospital №5, Barnaul» for the same period. Data processing was performed using calculation of intensive and extensive indicators, calculation of the arithmetic mean (X) and standard error of the average (m). Calculations were made using the STATISTICA-10 program. Consistently high rates were recorded, with an average of 64.32 ± 3.46 per 100,000 population. The percentage of hospitalized adults averaged 18.5% during the study period. Adults aged 18‑30 were more likely to be admitted to the hospital (90.3%); 41.6% were students. Adults with moderate severity were hospitalized more often (70.6%); 7 patients (1.3%) had complications: aphthous stomatitis (3 cases), pustulosis (2 cases), and pneumonia (2 cases). Patients with severe severity of the disease accounted for 2.4%, the premorbid background was burdened in 48% (HIV infection, tuberculosis). In 35% of patients with severe severity, the final diagnosis of Herpes zoster was made, all patients older than 40 years, stayed in the hospital for 20‑25 days.

scholarly journals Paediatric Idiopathic Intracranial Hypertension (IIH)—A Review

Life ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 632
Author(s):  
Andrew Malem ◽  
Twishaa Sheth ◽  
Brinda Muthusamy
Keyword(s):  
Intracranial Hypertension ◽  
Idiopathic Intracranial Hypertension ◽  
Adult Population ◽  
Underlying Disease ◽  
Diagnostic Process ◽  
Paediatric Patients ◽  
Disease Aetiology ◽  
Sight Loss ◽  
Chronic Headaches ◽  
Work Up

Paediatric idiopathic intracranial hypertension (IIH), is a rare but important differential diagnosis in children presenting with papilloedema. It is characterised by raised intracranial pressure in the absence of an identifiable secondary structural or systemic cause and is, therefore, a diagnosis of exclusion. In the adult population, there is a strong predilection for the disease to occur in female patients who are obese. This association is also seen in paediatric patients with IIH but primarily in the post-pubertal cohort. In younger pre-pubertal children, this is not the case, possibly reflecting a different underlying disease aetiology and pathogenesis. Untreated IIH in children can cause significant morbidity from sight loss, chronic headaches, and the psychological effects of ongoing regular hospital monitoring, interventions, and medication. The ultimate goal in the management of paediatric IIH is to protect the optic nerve from papilloedema-induced optic neuropathy and thus preserve vision, whilst reducing the morbidity from other symptoms of IIH, in particular chronic headaches. In this review, we will outline the typical work-up and diagnostic process for paediatric patients with suspected IIH and how we manage these patients.

Disability and psychiatric disorders in an urban community: measurement, prevalence and outcomes

1998 ◽  
Vol 28 (3) ◽  
pp. 509-517 ◽  
Author(s):  
S. S. BASSETT ◽  
G. A. CHASE ◽  
M. F. FOLSTEIN ◽  
D. A. REGIER
Keyword(s):  
Psychiatric Disorders ◽  
Service Utilization ◽  
Adult Population ◽  
Diagnostic Category ◽  
Psychiatric Evaluation ◽  
Chronic Medical Conditions ◽  
Medical Conditions ◽  
Sampling Weights ◽  
Co Morbidity ◽  
Specific Disability

Background. The purpose of this analysis was to examine: (1) the prevalence of psychiatric disorders among disabled people, using seven different measures of disability; (2) variation in disability between and within psychiatric diagnostic categories; and (3) relationship of diagnosis and disability to health service utilization.Method. Data were drawn from Phase I and Phase II of the Eastern Baltimore Mental Health Survey, part of the Epidemiologic Catchment Area Program (ECA) conducted in 1980–1 to survey mental morbidity within the adult population. A total of 810 individuals received both a household interview and a standardized clinical psychiatric evaluation. Estimated prevalence rates were computed using appropriate survey sampling weights.Results. Prevalence of disability ranged from 2·5 to 19·5%, varying with specific disability measure. Among those classified as disabled by any of the measures examined, 56 to 92% had a psychiatric disorder and serious chronic medical conditions were present in the majority of these cases (54 to 78%). Disability was expressed differently among the various diagnostic groups. Diagnostic category and disability were significant independent predictors of medical service utilization and receipt of disability payments.Conclusions. The majority of disabled adults living in the community have diagnosable psychiatric disorders, with the majority of these individuals suffering from significant chronic medical conditions as well, thus making co-morbidity the norm.

Protein-losing enteropathy as precursor of inflammatory bowel disease: a review of the literature

2021 ◽  
Vol 14 (1) ◽  
pp. e238802
Author(s):  
Fritz Ruprecht Murray ◽  
Bernhard Morell ◽  
Luc Biedermann ◽  
Philipp Schreiner
Keyword(s):  
Inflammatory Bowel Disease ◽  
Liver Cirrhosis ◽  
Female Patient ◽  
Bowel Disease ◽  
Final Diagnosis ◽  
Gastrointestinal Diseases ◽  
Review Of The Literature ◽  
Protein Losing Enteropathy ◽  
Inflammatory Bowel ◽  
Work Up

We report the case of a 63-year-old female patient with liver cirrhosis who presented with symptoms of severe hypoalbuminaemia and diarrhoea. After ruling out other causes of hypoalbuminaemia and confirmation of an elevated faecal α-1 antitrypsin clearance, the diagnosis of protein-losing enteropathy (PLE) could be established. Since PLE is a syndrome caused by various diseases, classified into erosive and non-erosive gastrointestinal diseases or lymphatic obstruction, an extensive work-up was necessary, establishing the final diagnosis of Crohn’s disease.

Primary leptomeningeal lymphoma masquerading as infectious tubercular meningitis

2021 ◽  
Vol 14 (9) ◽  
pp. e243574
Author(s):  
Salini Sumangala ◽  
Thidar Htwe ◽  
Yousuf Ansari ◽  
Lidia Martinez- Alvarez
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Correct Diagnosis ◽  
Central Nervous System Lymphoma ◽  
Final Diagnosis ◽  
Csf Analysis ◽  
Antitubercular Treatment ◽  
Lymphoma Treatment ◽  
Work Up ◽  
Timely Treatment

Primary central nervous system lymphoma (PCNSL) is infrequent and often poses diagnostic conundrums due to its protean manifestations. We present the case of a South Asian young man presenting with raised intracranial pressure and a lymphocytic cerebrospinal fluid (CSF) with pronounced hypoglycorrhachia. Progression of the neuro-ophthalmic signs while on early stages of antitubercular treatment led to additional investigations that produced a final diagnosis of primary leptomeningeal lymphoma. Treatment with chemoimmunotherapy (methotrexate, cytarabine, thiotepa and rituximab (MATRix)) achieved full radiological remission followed by successful autologous transplant. This case highlights the difficulties and diagnostic dilemmas when PCNSL presents as a chronic meningeal infiltrative process. While contextually this CSF is most often indicative of central nervous system tuberculosis and justifies empirical treatment initiation alone, it is essential to include differential diagnoses in the investigation work-up, which also carry poor prognosis without timely treatment. High suspicion, multidisciplinary collaboration and appropriate CSF analysis were the key for a correct diagnosis.

scholarly journals Validity and underrecording of diagnosis of COPD in the Danish National Patient Registry

2011 ◽  
Vol 105 (7) ◽  
pp. 1063-1068 ◽  
Author(s):  
Reimar W. Thomsen ◽  
Peter Lange ◽  
Birthe Hellquist ◽  
Ejvind Frausing ◽  
Paul D. Bartels ◽  
...  
Keyword(s):  
Patient Registry ◽  
National Patient Registry ◽  
Danish National Patient Registry ◽  
National Patient

scholarly journals A cross sectional study on alcoholism and its comorbidity patterns among urban adult population in Salem Tamil Nadu

2019 ◽  
Vol 6 (7) ◽  
pp. 2861
Author(s):  
Dhanasekar Gurupatham ◽  
Jeevithan Shanmugam
Keyword(s):  
Alcohol Use ◽  
Tamil Nadu ◽  
Adult Population ◽  
Data Entry ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Co Morbidity ◽  
Study Participants ◽  
Salem District

Background: Alcohol use is associated with serious public health problems thereby raising the global morbidity and mortality. The main aim of this study is to estimate the prevalence of alcoholism and its co morbidity pattern among urban adult population in Salem district, Tamil Nadu.Methods: A community based cross-sectional study was carried out among urban adult population in Salem district involving 493 participants. Convenient sampling method was used. Informed consent was obtained from each participant and information was collected by using a predesigned structured questionnaire. Microsoft Excel 2007 was used for data entry and SPSS version 24 was used for data analysis.Results: It was found from the study that the prevalence of alcoholism was high. Alcohol use in any form was found in 38% of the study participants. 8% of the participants confessed that alcohol is an eye opener to them. 6% of the participants lost their job and 15% of the participants were hospitalised due to alcohol.Conclusions: The study showed higher prevalence of alcohol use among urban adult population in Salem district. Awareness about the ill effects of alcoholism among the population and necessary rehabilitation will help to reduce alcoholism consumption and its related disorders.

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