Association Between Gestational Bell’s Palsy and Preeclampsia and Other Pregnancy-Related Metabolic Disorders: A Retrospective Comparative Case Study
Abstract BackgroundThe associations between gestational Bell’s palsy (GBP) and preeclampsia (PE) and other pregnancy-related metabolic disorders such as gestational hypertension (GHT) and gestational diabetes mellitus (GDM) remain unclear. We aimed to evaluate these associations and to compare the neonatal outcomes between the newborns of pregnant women with and without GBP.MethodsThis was a retrospective 1:5 comparative case study between pregnant women with and without GBP. GBP cases in Songklanagarind Hospital from 2006 to 2016 were enrolled. The exact maternal age and order of gravidity at the onset of GBP were matched. The associations between GBP and PE, GHT and GDM were evaluated comparatively. Also, the outcomes of newborns from the two pregnant women groups were compared and analyzed by univariable analysis (p<0.05).ResultsEight GBP cases out of 8,756 pregnant women were enrolled. Six of the GBP cases were first or second gravidity pregnancies. Five cases developed GBP during the third trimester. Except for significantly higher median systolic and diastolic blood pressures (SBP and DBP) in the GBP cases, we found no significant associations between GBP and PE, GHT or GDM. Additionally, the neonates of the GBP women had significantly lower mean birth weight.ConclusionsWe found that GBP had no associations with PE, GHT or GDM. However, significantly lower birth weight was found in the newborns of the GBP women. The higher median SBP and DBP found in the GBP women may imply that a common pathogenesis of microvasculopathy between GBP and late pregnancy-related complications exists.