scholarly journals Adequate Animal Protein Intake Maintains Normal Thyroid Antibody Levels in Pregnant Women With Mild Iodine Deficiency

2021 ◽  
Author(s):  
Zhengyuan Wang ◽  
Jiaying Shen ◽  
Qi Song ◽  
Xueying Cui ◽  
Zehuan Shi ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Iodine Deficiency ◽  
Total Protein ◽  
Protein Intake ◽  
Animal Protein ◽  
Negative Group ◽  
Positive Group ◽  
Thyroid Antibody ◽  
Total Protein Intake ◽  
Antibody Levels

Abstract Background: Both of the iodine and animal protein may affect thyroid function. We explored the association between animal protein intake and thyroid antibody status in pregnant women after universal salt iodization.Method: Pregnant women were enrolled by using a multistage, stratified random sampling method. 4,646 eligible participants were interviewed in person with questionnaires physical examination and thyroid antibody test. Results: Only thyrotropin receptor antibodies (TR-Ab) positive rates were different among different animal protein intake groups. The median of urinary iodine concentration (UIC) in thyroid peroxidase antibodies (TPO-Ab) positive groups was higher than the negative group. The median of total protein intake, animal protein intake and UIC in TR-Ab positive group was higher than the negative group. The medians of total protein intake and UIC in TPO-Ab/TG-Ab/TR-Ab positive group were higher than the negative group. The above differences were statistically significant (P < 0.05). The multivariable logistic regression results showed that insufficient iodine had a negative correlation with TPO-Ab positive and TR-Ab positive (P < 0.05). The middle third and top third animal protein intakes served as protective factors for TR-Ab (coefficient = 0.559, 95% CI = 0.415–0.752; coefficient = 0.0.406, 95% CI = 0.266–0.621) and positive TPO-Ab/TR-Ab/TG-Ab (coefficient = 0.817, 95% CI = 0.687–0.971; coefficient = 0.805, 95% CI= 0.672–0.964). Conclusions: Adequate animal protein intake protects against elevated anti-thyroid antibody levels in pregnant women with mild iodine deficiency.

scholarly journals Protein Intake by Source and Breast Cancer Incidence and Mortality: The Women’s Health Initiative

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Kathy Pan ◽  
Joseph C Larson ◽  
Ross L Prentice ◽  
Joanne E Mortimer ◽  
Marian L Neuhouser ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Total Protein ◽  
Protein Intake ◽  
Vegetable Protein ◽  
Breast Cancer Incidence ◽  
Animal Protein ◽  
Breast Cancers ◽  
Risk Of Death ◽  
Total Protein Intake

Abstract Background Prior studies of dietary protein intake and breast cancer have been mixed and were limited by dietary self-report measurement error. Methods Biomarker-calibrated total protein intake and estimated vegetable protein and animal protein intake were determined from baseline food frequency questionnaires in 100 024 Women’s Health Initiative participants. Associations between total, animal, and vegetable protein intake and breast cancer incidence, deaths from breast cancer, and deaths after breast cancer were estimated using Cox proportional hazards regression. Breast cancers were verified by medical record review and survival outcomes enhanced by National Death Index queries. All statistical tests were 2-sided. Results After 14 years of follow-up, there were 6340 incident breast cancers, 764 deaths from breast cancer, and 2059 deaths after breast cancer. In multivariable analyses, higher calibrated total protein intake was not associated with breast cancer incidence or deaths from or after breast cancer. Vegetable protein intake was associated with statistically significantly lower breast cancer incidence (hazard ratio [HR] = 0.98, 95% confidence interval [CI] = 0.96 to 0.99, Ptrend = .006) and statistically significantly lower risk of death after breast cancer (HR = 0.93, 95% CI = 0.91 to 0.97, Ptrend &lt; .001) but not with deaths from breast cancer. In contrast, higher animal protein intake was associated with statistically significantly higher breast cancer incidence (HR = 1.03, 95% CI = 1.01 to 1.06, Ptrend = .02) but not with deaths from or after breast cancer. Conclusions Calibrated total protein intake was not associated with breast cancer incidence or mortality. Higher vegetable protein intake was associated with lower breast cancer incidence and lower risk of death after breast cancer. Higher animal protein intake was associated with higher breast cancer incidence.

scholarly journals Global Intakes of Total Protein and Sub-types; Findings from the 2015 Global Dietary Database (P10-050-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Julia Reedy ◽  
Frederick Cudhea ◽  
Peilin Shi ◽  
Jianyi Zhang ◽  
Jennifer Onopa ◽  
...  
Keyword(s):  
Middle East ◽  
North Africa ◽  
Total Protein ◽  
Protein Intake ◽  
Animal Protein ◽  
Sub Saharan Africa ◽  
Plant Protein ◽  
Macronutrient Intake ◽  
Omega 3 ◽  
Total Protein Intake

Abstract Objectives Adequate macronutrient intake is critical for child growth and health and the prevention of non-communicable diseases. Presently, the global distributions of macronutrient intake are not well established. Our objective was to comprehensively estimate daily intakes of total, animal, and plant protein, and additional macronutrients for individuals of all ages from 185 countries in 2015. Methods We collected and analyzed individual-level dietary intake data from nationally or sub-nationally-representative surveys, comprising 1137 survey-years of data representing 185 countries (97% of the world's population). Using a Bayesian hierarchical model, we estimated mean macronutrient intake by country, time (35 years), age (15 groups), sex, education (3 levels), urban or rural residence, and pregnancy status (when applicable). The primary model incorporated the number of subjects in each stratum, sampling representativeness, dietary assessment method, type of dietary metric, availability from the United Nations FAO, and country, and superregion (6 groupings of regions) random effects as covariates. Results In 2015, global total protein intake was 78.2 g/day, ranging from 61.0 g in the Middle East and North Africa to 92.5 g/day in Asia. Mean national total protein intake was ≥46 g/day in all 185 countries. Global animal protein intake was 33.3 g/day and intake was highest in Latin American and the Caribbean (42.8 g/day) and lowest in Sub-Saharan Africa (38.3 g/day). The countries with the lowest mean national animal protein intake were Bangladesh (7.2 g/day) and Nepal (10.1 g/day). Global plant protein intake was 29.1 g/day. Region-specific intake was highest in the Middle East and North Africa (32.1 g/day) and lowest in the Former Soviet Union (25.5 g/day). Plant protein intake was usually greater in males than females. Additional findings for dairy protein, carbohydrate, added sugar, fiber, total fat, saturated fat, polyunsaturated fat, seafood omega-3 fat, plant omega-3 fat, and trans-fat will be presented at the meeting. Conclusions Our results show trends and variation in protein worldwide, by region, and by country. These data provide the best available global evidence on macronutrient intakes and are valuable for informing public health policy and disease prevention efforts. Funding Sources Bill & Melinda Gates Foundation. Supporting Tables, Images and/or Graphs

scholarly journals Dietary Protein Sources and Muscle Mass over the Life Course: The Lifelines Cohort Study

Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1471 ◽  
Author(s):  
Nikita Alexandrov ◽  
Coby Eelderink ◽  
Cécile Singh-Povel ◽  
Gerjan Navis ◽  
Stephan Bakker ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Dietary Protein ◽  
Total Protein ◽  
Protein Intake ◽  
Animal Protein ◽  
Creatinine Excretion ◽  
Protein Sources ◽  
Fish Meat ◽  
Total Protein Intake ◽  
Egg Protein

The influence of dietary protein intake on muscle mass in adults remains unclear. Our objective was to investigate the association between protein intake and muscle mass in 31,278 men and 45,355 women from the Lifelines Cohort. Protein intake was estimated by food frequency questionnaire and muscle mass was estimated from 24 h urinary creatinine excretion. The age range was 18–91 years and mean total protein intake was 1.0 ± 0.3 g/kg/day. Across increasing quartiles of total protein intake, animal protein intake, and fish/meat/egg protein intake, creatinine excretion significantly increased in both men (+4% for total and +6% for fish/meat/egg protein intake, p < 0.001) and women (+3% for total and +6% for fish/meat/egg protein intake, p < 0.001). The associations were not systematically stronger or weaker with increasing age, but associations were strongest for young men (26–45 years) and older women (>75 years). The association between total protein intake and muscle mass was dependent on physical activity in women (p interaction < 0.001). This study suggests that total protein intake, animal protein intake, and in particular fish/meat/egg protein intake may be important for building and preserving muscle mass. Dietary protein sources should be further studied for their potential to build and preserve muscle mass.

Linkage between H. pylori Infection and TNF-α polymorphism in The Pregnant Women

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Ghaidaa Raheem Lateef ◽  
Azhar Omaran Al-Thahab
Keyword(s):  
Pregnant Women ◽  
Serum Antibody ◽  
Rapid Test ◽  
Negative Group ◽  
Positive Group ◽  
Gynecology And Obstetrics ◽  
Tnf Α ◽  
Significant Difference ◽  
Pcr Products ◽  
H Pylori

A study was performed on 100 pregnant women in the outpatient department of gynecology and obstetrics of Maternity and Children Hospital in Al-Diwaniya City during the period between (March to September 2016). One hundred blood samples (50 for patients and 50 for control) were collected under the supervision of the treating gynecologist. The detection of Helicobacter. pylori was done by the use of the serum antibody Rapid test. The results showed that 50 (100%) were positive and 50 (100%) were negative for H. pylori in above method.All blood of patients and control samples were used for the extraction of genomic DNA,where the 107 bp PCR product size. Genotyping of the TNF-α-308 SNP (G/A)was performed by restriction fragment length polymorphism PCR (RFLP-PCR). PCR products were digested with restr NcoI iction enzyme. Individuals with the TNF-α-308(GG) homozygote produced digested DNA bands at 80,and 20 bp bp. A heterozygous genotype ofTNF-α-308 (GA)produced 107 bp,80 bp,and 20 bp bands. Individuals with the TNF-α-308 (AA) homozygote genotype had no amplicon digested and generated only one band of 107 bp. There was a significant difference in the frequency of the TNF-α-308(GG)genotype between H. pylori positive group and H. pylori negative group(72%,78% respectively). Also for GA genotype,there was a significant difference between H. pylori positive group and H. pylori negative group(24%,18% respectively). Concerning the frequency of the TNF-α-308 (AA)genotype between H. pylori positive group and H. pylori negative group,there was no significant difference between the two groups.

scholarly journals Dietary Intake, Nutritional Adequacy, and Food Sources of Protein and Relationships with Personal and Family Factors in Spanish Children Aged One to < 10 Years: Findings of the EsNuPI Study

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1062
Author(s):  
Casandra Madrigal ◽  
María José Soto-Méndez ◽  
Ángela Hernández-Ruiz ◽  
Teresa Valero ◽  
Federico Lara Villoslada ◽  
...  
Keyword(s):  
Dietary Protein ◽  
Total Protein ◽  
Dairy Products ◽  
Protein Intake ◽  
Meat Products ◽  
Food Sources ◽  
Animal Origin ◽  
Total Protein Intake ◽  
Fish And Shellfish ◽  
Milk And Dairy Products

Diet in the first years of life is an important factor in growth and development. Dietary protein is a critical macronutrient that provides both essential and nonessential amino acids required for sustaining all body functions and procedures, providing the structural basis to maintain life and healthy development and growth in children. In this study, our aim was to describe the total protein intake, type and food sources of protein, the adequacy to the Population Reference Intake (PRI) for protein by the European Food Safety Authority (EFSA), and the Recommended Dietary Allowance (RDA) by the Institute of Medicine (IoM). Furthermore, we analyzed whether the consumption of dairy products (including regular milk, dairy products, or adapted milk formulas) is associated with nutrient adequacy and the contribution of protein to diet and whole dietary profile in the two cohorts of the EsNuPI (in English, Nutritional Study in the Spanish Pediatric Population) study; one cohort was representative of the Spanish population from one to < 10 years old (n = 707) (Spanish reference cohort, SRS) who reported consuming all kinds of milk and one was a cohort of the same age who reported consuming adapted milk over the last year (including follow-on formula, growing up milk, toddler’s milk, and enriched and fortified milks) (n = 741) (adapted milk consumers cohort, AMS). The children of both cohorts had a high contribution from protein to total energy intake (16.79% SRS and 15.63% AMS) and a high total protein intake (60.89 g/day SRS and 53.43 g/day AMS). We observed that protein intake in Spanish children aged one to < 10 years old was above the European and international recommendations, as well as the recommended percentages for energy intakes. The main protein sources were milk and dairy products (28% SRS and 29% AMS) and meat and meat products (27% SRS and 26% AMS), followed by cereals (16% SRS and 15% AMS), fish and shellfish (8% in both cohorts), eggs (5% SRS and 6% AMS), and legumes (4% in both cohorts). In our study population, protein intake was mainly from an animal origin (meat and meat products, milk and dairy products, fish and shellfish, and eggs) rather than from a plant origin (cereals and legumes). Future studies should investigate the long-term effect of dietary protein in early childhood on growth and body composition, and whether high protein intake affects health later in life.

scholarly journals The Relationships between Total Protein Intake, Protein Sources, Physical Activity, and Lean Mass in a Representative Sample of the US Adults

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3151
Author(s):  
Furong Xu ◽  
Jacob E. Earp ◽  
Maya Vadiveloo ◽  
Alessandra Adami ◽  
Matthew J. Delmonico ◽  
...  
Keyword(s):  
Physical Activity ◽  
Lean Mass ◽  
Total Protein ◽  
Representative Sample ◽  
Protein Intake ◽  
Large Scale ◽  
Weight Status ◽  
Protein Sources ◽  
Total Protein Intake ◽  
Study Results

Background: Although dietary protein and physical activity play essential roles in developing and preserving lean mass, studies exploring these relationships are inconsistent, and large-scale studies on sources of protein and lean mass are lacking. Accordingly, the present study examined the relationship between total protein intake, protein sources, physical activity, and lean mass in a representative sample of US adults. Methods: This cross-sectional study analyzed data from 2011–2016 US National Health and Nutrition Examination Survey and corresponding Food Patterns Equivalents Database (n = 7547). Multiple linear regression models were performed to examine the sex-specific associations between total protein intake, protein sources (Dairy, Total Protein Foods, Seafood, and Plant Proteins), physical activity, and lean mass adjusting for demographics, weight status, and total daily energy intake. Results: Total protein intake was inversely related to lean mass in females only (Lean mass index: β= −0.84, 95%CI: −1.06–−0.62; Appendicular lean mass index: β= −0.35, 95%CI: −0.48–−0.22). However, protein sources and physical activity was positively associated with lean mass in males and/or females (p < 0.05). Conclusion. Study results suggest that consuming more protein daily had a detrimental influence on lean mass in females whereas eating high-quality sources of proteins and being physically active are important for lean mass for men and women. However, the importance of specific protein sources appears to differ by sex and warrants further investigation.

scholarly journals The Relationship Between Healthy Eating Motivation and Protein Intake in Community-Dwelling Older Adults With Varying Functional Status

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 662
Author(s):  
Hanna M. Rempe ◽  
Gudrun Sproesser ◽  
Anne Hannink ◽  
Thomas Skurk ◽  
Beate Brandl ◽  
...  
Keyword(s):  
Older Adults ◽  
Functional Status ◽  
Healthy Eating ◽  
Total Protein ◽  
Protein Intake ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Protein Sources ◽  
Total Protein Intake ◽  
The Relationship

In older adults, the relationship between healthy eating motivation (HEM) and protein intake as key component of a healthy diet is poorly understood. Therefore, we investigate the association of HEM with (1) total protein intake and (2) intake of different protein sources in older adults with varying functional status. In this cross-sectional study including 250 adults (≥70 years), we assessed HEM with “The Eating Motivation Survey” and protein intake by 7-day food records. In addition, gender, age, Body Mass Index (BMI), energy intake and functional status were considered. Regression analyses revealed that HEM was neither related to total (β = −0.02; p = 0.723) nor to relative protein intake (β = 0.04; p = 0.370). Notwithstanding this, participants with stronger HEM showed lower intake of protein from meat and meat products (β = −0.14; p = 0.018), higher intake of overall plant-based protein (β = 0.11; p = 0.032), protein from fruit and vegetables (β = 0.20; p = 0.002) and from pulses, nuts an seeds (β = 0.16; p = 0.016). Our findings suggest HEM as a valuable indicator for intake of distinct protein sources. However, since HEM is not related to total protein intake, the importance of sufficient protein consumption should be emphasized by promoting healthy eating, regardless of self-perceived HEM.

scholarly journals Protein intake per day and at each daily meal and skeletal muscle mass declines among older community dwellers in Japan

2019 ◽  
Vol 23 (6) ◽  
pp. 1090-1097 ◽  
Author(s):  
Rei Otsuka ◽  
Yuki Kato ◽  
Chikako Tange ◽  
Yukiko Nishita ◽  
Makiko Tomida ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Mass ◽  
Total Protein ◽  
Protein Intake ◽  
Skeletal Muscle Mass ◽  
Total Protein Intake ◽  
Dietary Records ◽  
Logistic Modelling ◽  
Community Dwellers

AbstractObjective:To examine associations between protein intake per day and at different meals and skeletal muscle mass declines.Design:Two-year prospective cohort study among older community dwellers.Setting:National Institute for Longevity Sciences–Longitudinal Study of Aging (NILS-LSA) in Japan.Participants:Older men (n 292) and women (n 363) aged 60–87 years who participated in the baseline (2006–2008) and follow-up studies (2008–2010) of NILS-LSA and did not exhibit low skeletal muscle mass at baseline. Muscle mass was assessed using dual-energy X-ray absorptiometry at baseline and follow-up. Low muscle mass was defined as skeletal muscle mass index <7·0 kg/m2 for men and <5·4 kg/m2 for women at follow-up. Daily protein intake and protein intake at each meal were calculated from 3 d dietary records at baseline and sex-stratified tertiles were determined.Results:Mean (sd) protein intake at breakfast, lunch and dinner was 22·7 (7·8), 26·7 (9·3) and 37·4 (10·5) g for men and 19·3 (6·3), 23·2 (7·3) and 28·5 (7·0) g for women, respectively. After adjusting for age, baseline skeletal muscle mass and other confounders in logistic modelling, greater total protein intake was associated with lower prevalence of skeletal muscle mass decline among men at follow-up (P = 0·024). Particularly, the OR (95 % CI) for high lunchtime protein intake was low (0·11 (0·02, 0·61); P = 0·01). No significant association between total protein intake and prevalence of skeletal muscle mass decline was found among women.Conclusions:High total protein intake, particularly at lunchtime, is associated with retention of skeletal muscle mass in men.

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