scholarly journals Assessment of Safety and Efficacy of Ultra-micro Transconjunctival Lower Eyelid Bags Removal Combined with Orbital Fat Transfer

2021 ◽  
Author(s):  
Ke-xue Wang ◽  
Xiong Xiang ◽  
Jian-feng Zhang ◽  
Man-cang Ma
Keyword(s):  
Retrospective Chart Review ◽  
Lower Eyelid ◽  
Postoperative Recovery ◽  
Control Group ◽  
Observation Group ◽  
Fat Transfer ◽  
Orbital Fat ◽  
Significant Difference ◽  
The Difference

Abstract BackgroundThe elaboration of a precise operation is essential during lower eyelid blepharoplasty. The aim of this study was to investigate the clinical effect of ultra-micro transconjunctival lower eyelid bags removal combined with orbital fat transfer in the correction of lower eyelid bags. MethodsA total of 226 patients underwent lower eyelid blepharoplasty in our department during the past 3 years (2018-2020). Excluded were patients with previous eyelid surgery, diplopia, strabismus and associated procedures. A retrospective chart review of patients undergoing traditional transconjunctival blepharoplasty (n=104) and ultra-micro transconjunctival lower eyelid bags removal combined with orbital fat transfer (n=122) was performed. The length of follow-up ranged between 24 hours and 3 months after operation. ResultsThe control group (conventional conjunctival blepharoplasty) included 45 males and 59 females with an average age of (44.5±3.5) years, while the observation group (subconjunctival blepharoplasty with orbital fat transfer) included 49 males and 73 females with an average age of (43.1±4.2) years. There were no statistically significant differences between the two groups in gender (p = 0.27) and age (p = 0.44) (p > 0.05). The Clinical improvement of the observation group is significantly higher than the control group, after 5 days has significant statistical differences between two groups (P < 0.05). It was found that the clinical efficiency of the observation group was significantly higher than that of the control group (P < 0.05). Next, we compared the complications between the two groups and found that there was a significant difference between the two groups (P < 0.05). The satisfaction of the two groups at different follow-up times was compared: 1 day after the operation, the satisfaction of the observation group was 52.5%, and that of the control group was 32.5%, with no statistically significant difference (P > 0.05). The satisfaction of the observation group was higher than that of the control group at 3d and 1 month after surgery, and the difference was statistically significant (P < 0.05).ConclusionThe application of ultra-micro transconjunctival lower eyelid bags removal combined with orbital fat transfer can correct the lower eyelid bag safely and effectively with short postoperative recovery time, high patient satisfaction and low complication rate. This advanced technical skill may significantly improve the treatment of lower eyelid bags.

scholarly journals Effect of manual reduction and indirect decompression on thoracolumbar burst fracture: a comparison study

2020 ◽  
Author(s):  
Jian Huang ◽  
Limin Zhou ◽  
Zhaodong Yan ◽  
Zongbo Zhou ◽  
Xuejian Gou
Keyword(s):  
Burst Fracture ◽  
Wedge Angle ◽  
Control Group ◽  
Thoracolumbar Burst Fracture ◽  
Manual Reduction ◽  
Significant Difference ◽  
Indirect Decompression ◽  
The Difference ◽  
Experimental Group

Abstract Study designRetrospective cohort study.ObjectiveTo evaluate the effect of manual reduction and indirect decompression on thoracolumbar burst fracture.Methods60 patients with thoracolumbar burst fracture who were hospitalized from January 2018 to October 2019 were selected and divided into experimental group (33 cases) and control group (27 cases) according to different treatment methods. The experimental group was treated with manual reduction and indirect decompression, while the control group was not treated with manual reduction. The operation time and intraoperative blood loss were recorded. VAS score was used to evaluate the improvement of pain. The anterior height of injured vertebra, wedge angle of injured vertebral body, encroachment ratio of injured vertebral canal were used to evaluate spinal canal decompression and fracture reduction. JOA score was used to evaluate the improvement of spinal function.ResultsThere was no significant difference in operation time and intraoperative blood loss between the two groups. Compared with the control group, the VAS score and the wedge angle of injured vertebral body of the experimental group on 3 days after operation and the last follow-up were significantly lower than that of the control group, and the difference was statistically significant. The ratio of anterior height of injured vertebra of the experimental group on 3 days after operation and the last follow-up were significantly higher than that of the control group, and the difference was statistically significant. The difference of the encroachment ratio of injured vertebral canal between preoperation and 3 days after operation was significantly higher than that of the control group, and the difference was statistically significant. The bladder function of JOA on 3 days after operation of the experimental group was significantly higher than that of the control group, and the difference was statistically significant. And the rest aspect of JOA on 3 days after operation and last follow-up of the experimental group were no significant difference Compared with the control group.ConclusionManipulative reduction and indirect decompression can obtain better clinical effect in the treatment of thoracolumbar burst fractures.

scholarly journals Efficacy of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in the Management of Malignant Ascites

2020 ◽  
Author(s):  
Jie Jiao ◽  
Chengzhen Li ◽  
Guanying Yu ◽  
Lei Zhang ◽  
Xiaoyan Shi ◽  
...  
Keyword(s):  
Intraperitoneal Chemotherapy ◽  
Adverse Reactions ◽  
Total Effective Rate ◽  
Malignant Ascites ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Short Term ◽  
Significant Difference ◽  
The Difference

Abstract Objective: The purpose of this study is to compare the difference of clinical efficacy between conventional intraperitoneal chemotherapy and HIPEC, so as to explore the clinical application value and advantages of HIPEC.Design: A retrospective analysis was conducted on 80 patients with malignant ascites admitted to our hospital from June 2017 to June 2019. The general clinical data and qualitative data of the treatment results of 80 patients with malignant ascites were processed by SPSS19.0 using χ2 test and quantitative data were processed by t test. P <0.05, statistical data can be considered statistically significant.Results: 1. There was no significant change in vital signs and temperature in the observation group during the treatment, and the difference was not statistically significant 2. The short-term total effective rate of patients in the observation group was 91.11%, and the short-term total effective rate of the patients in the control group was 40%.3. There was no significant difference in the incidence of adverse reactions between the two groups of patients.Conclusion: Intraperitoneal hyperthermic chemotherapy combined with intravenous chemotherapy can significantly control malignant ascites, and has small adverse reactions, which is worthy of clinical promotion and application.

scholarly journals Effect of Metoprolol on Cardiac Function and Prognosis in Patients with Dilated Cardiomyopathy

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Huailing Su ◽  
Bin Li ◽  
Zhisheng Jia
Keyword(s):  
Cardiac Function ◽  
Dilated Cardiomyopathy ◽  
Adverse Reactions ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Control Group ◽  
Observation Group ◽  
Significant Difference ◽  
Conventional Methods ◽  
The Difference

Objective: To investigate the effect of metoprolol on cardiac function and prognosis in patients with dilated cardiomyopathy. Methods: 100 patients with dilated cardiomyopathy treated in our hospital from January 2018 to December 2019 were randomly divided into control group (n = 50) and observation group (n = 50). The control group was treated with conventional methods, and the observation group was treated with conventional methods and metoprolol for 6 months. The cardiac function [left ventricular ejection fraction (LVEF), stroke volume (SV), cardiac output (CO)] and prognosis [Glasgow Outcome Scale (GOS) score] of the two groups before and at the end of 6 months of intervention were compared, and the incidence of adverse reactions of the two groups were compared. Results: After 6 months of treatment, the levels of LVEF, SV and CO in the two groups were higher than before treatment, and the comparison level between the observation group and the control group was higher, the difference was statistically significant (P  < 0.05);After 6 months of treatment, the GOS score of the observation group was higher than that of the control group, and the difference was statistically significant (P < 0.05);There was no significant difference in the total incidence of adverse reactions between the two groups (P > 0.05). Conclusion:  Metoprolol can improve the cardiac function and prognosis of patients with dilated cardiomyopathy, without increasing the incidence of adverse reactions.

scholarly journals Effect of manual reduction and indirect decompression on thoracolumbar burst fracture: a comparison study

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Jian Huang ◽  
Limin Zhou ◽  
Zhaodong Yan ◽  
Zongbo Zhou ◽  
Xuejian Gou
Keyword(s):  
Burst Fracture ◽  
Wedge Angle ◽  
Control Group ◽  
Thoracolumbar Burst Fracture ◽  
Manual Reduction ◽  
Significant Difference ◽  
Indirect Decompression ◽  
The Difference ◽  
Experimental Group

Abstract Objective To evaluate the effect of manual reduction and indirect decompression on thoracolumbar burst fracture. Methods Sixty patients with thoracolumbar burst fracture who were hospitalized from January 2018 to October 2019 were selected and divided into an experimental group (33 cases) and control group (27 cases) according to different treatment methods. The experimental group was treated with manual reduction and indirect decompression, while the control group was not treated with manual reduction. The operation time and intraoperative blood loss were recorded. VAS score was used to evaluate the improvement of pain. The anterior height of the injured vertebra, wedge angle of the injured vertebral body, and encroachment ratio of the injured vertebral canal were used to evaluate the spinal canal decompression and fracture reduction. JOA score was used to evaluate the improvement of spinal function. Results There was no significant difference in operation time and intraoperative blood loss between the two groups. Compared with the control group, the VAS score and the wedge angle of the injured vertebral body of the experimental group 3 days after the operation and the last follow-up were significantly lower than that of the control group, and the difference was statistically significant. The ratio of the anterior height of the injured vertebra of the experimental group 3 days after the operation and the last follow-up was significantly higher than that of the control group, and the difference was statistically significant. The difference of the encroachment ratio of the injured vertebral canal between preoperation and 3 days after operation was significantly higher than that of the control group, and the difference was statistically significant. The bladder function of JOA 3 days after the operation of the experimental group was significantly higher than that of the control group, and the difference was statistically significant. And the rest aspect of JOA on 3 days after the operation and last follow-up of the experimental group has no significant difference compared with the control group. Conclusion Manipulative reduction and indirect decompression can obtain a better clinical effect in the treatment of thoracolumbar burst fractures.

scholarly journals Effects of Misoprostol and Oxytocin Combined with Calcium Gluconate on Delivery Time of Parturient with High-risk Postpartum Hemorrhage and Neonatal Outcomes

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Rongfang Chen ◽  
Wenwen Shuo
Keyword(s):  
High Risk ◽  
Calcium Gluconate ◽  
Apgar Score ◽  
Postpartum Hemorrhage ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Delivery Time ◽  
Significant Difference ◽  
The Difference

Objective: To investigate the effect of misoprostol and oxytocin combined with calcium gluconate on parturient with high-risk postpartum hemorrhage. Methods: The clinical data of 80 parturient with high-risk postpartum hemorrhage who were treated in our hospital from July 2016 to July 2019 were retrospectively analyzed. According to different treatment methods, they were divided into control group (treated with misoprostol combined with oxytocin, 40 cases) and observation group (treated with misoprostol and oxytocin combined with calcium gluconate, 40 cases), compared the clinical efficacy, delivery time, postpartum hemorrhage 2 hour after delivery, postpartum hemorrhage 24 hours after delivery and Apgar score of the newborns at 1min after birth. Results: The total effective rate (95.00%) in the observation group was higher than that in the control group (77.50%), and the difference was statistically significant (P<0.05). The third delivery stage in the observation group was shorter than that in the control group, and the postpartum hemorrhage volume was less than that in the control group. The difference was statistically significant (P<0.05). There was no significant difference in Apgar score of the two groups of newborns (P>0.05). Conclusion: Misoprostol and oxytocin combined with calcium gluconate is effective in treating high-risk postpartum hemorrhage parturient, which not only can effectively reduce postpartum hemorrhage and shorten the delivery time, but also is beneficial for neonatal outcome and worthy of clinical application.

scholarly journals Comparison of the Effect of Combined Cardiovascular Dexmedetomidine and Propofol in Minimally Invasive axillary Odor Surgery with Tumescent Anesthesia

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Chunfei Xu ◽  
Xiaoying Gao
Keyword(s):  
Postoperative Complications ◽  
Minimally Invasive ◽  
Postoperative Recovery ◽  
Control Group ◽  
Observation Group ◽  
Tumescent Anesthesia ◽  
Arterial Blood ◽  
Before And After ◽  
The Difference ◽  
Axillary Odor

Objective: The effects of combined dexmedetomidine hydrochloride and propofol in minimally invasive axillary odor surgery with tumescent anesthesia. Methods: A total of 46 patients underwent minimally invasive axillary odor surgery by tumescent anesthesia received in the hospital from May 2017 to January 2019 were divided into observation group (23 cases) and control group (23 cases) according to the random number table method. The control group used propofol, and the observation group underwent minimally invasive axillary odor combined with dexmedetomidine hydrochloride by tumescent anesthesia. The changes of arterial blood pressure (MAP), heart rate (HR) and postoperative complications before and after anesthesia were compared and analyzed between the two groups. Results: After anesthesia, MAP and HR in both groups were lower than before anesthesia, and the observation group was lower than the control group, the difference was statistically significant (P<0.05). Compared with the control group, the postoperative complications were less in the observation group, but the difference was not statistically significant (P>0.05). Conclusion: Compared with the use of propofol, the effect of dexmedetomidine hydrochloride combined with minimally invasive axillary odor surgery by tumescent anesthesia is more obvious, and the postoperative recovery is faster with fewer complications.

scholarly journals Compared benefits of educational programs dedicated to diabetic patients with or without community pharmacist involvement

2020 ◽  
Vol 21 ◽  
Author(s):  
Laura Foucault-Fruchard ◽  
Laura Bizzoto ◽  
Aude Allemang-Trivalle ◽  
Peggy Renoult-Pierre ◽  
Daniel Antier
Keyword(s):  
Community Pharmacist ◽  
Educational Interventions ◽  
Pharmacist Intervention ◽  
Educational Programs ◽  
Diabetes Control ◽  
Control Group ◽  
Diabetic Patients ◽  
Significant Difference ◽  
The Difference

Abstract Background: International guidelines on diabetes control strongly encourage the setting-up of therapeutic educational programs (TEP). However, more than half of the patients fail to control their diabetes a few months post-TEP because of a lack of regular follow-up by medical professionals. The DIAB-CH is a TEP associated with the follow-up of diabetic patients by the community pharmacist. Aim: To compare the glycated hemoglobin (HbA1c) and body mass index (BMI) in diabetic patients of Control (neither TEP-H nor community pharmacist intervention), TEP-H (TEP in hospital only) and DIAB-CH (TEP-H plus community pharmacist follow-up) groups. Methods: A comparative cohort study design was applied. Patients included in the TEP-H from July 2017 to December 2017 were enrolled in the DIAB-CH group. The TEP-H session was conducted by a multidisciplinary team composed of two diabetologists, two dieticians and seven nurses. The HbA1c level and the BMI (when over 30 kg/m2 at M0) of patients in Control (n = 20), TEP-H (n = 20) and DIAB-CH (n = 20) groups were collected at M0, M0 + 6 and M0 + 12 months. First, HbA1c and BMI were compared between M0, M6 and M12 in the three groups with the Friedman test, followed by the Benjamini-Hochberg post-test. Secondly, the HbA1c and BMI of the three groups were compared at M0, M6 and M12 using the Kruskal-Wallis test. Findings: While no difference in HbA1c was measured between M0, M6 and M12 in the Control group, Hb1Ac was significantly reduced in both TEP-H and DIAB-CH groups between M0 and M6 (P = 0.0072 and P = 0.0034, respectively), and between M0 and M12 only in the DIAB-CH group (P = 0.0027). In addition, a significant decrease in the difference between the measured HbA1c and the target assigned by diabetologists was observed between M0 and M6 in both TEP-H and DIAB-CH groups (P = 0.0072 and P = 0.0044, respectively) but only for the patients of the DIAB-CH group between M0 and M12 (P = 0.0044). No significant difference (P > 0.05) in BMI between the groups was observed. Conclusion: The long-lasting benefit on glycemic control of multidisciplinary group sessions associated with community pharmacist-led educational interventions on self-care for diabetic patients was demonstrated in the present study. There is thus evidence pointing to the effectiveness of a community/hospital care collaboration of professionals on diabetes control in primary care.

Dental Age Difference in Children with ADHD

2018 ◽  
Vol 42 (3) ◽  
pp. 208-211
Author(s):  
Puneet Wadhwa ◽  
Qingzhao Yu ◽  
Han Zhu ◽  
Janice A. Townsend
Keyword(s):  
Retrospective Chart Review ◽  
Control Group ◽  
Age Difference ◽  
Adhd Group ◽  
Dental Age ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
Significant Difference ◽  
The Difference ◽  
The Impact

Objective: The purpose of this study was to determine if changes in dental development are associated with Attention Deficit Hyperactivity Disorder (ADHD) or ADHD medications. Study Design: This retrospective chart review evaluated the dental age of 128 patients between 6 and 16 years of age using the Demirjian method from the following two groups a) children with ADHD b) unaffected children. The ADHD group was further stratified into four groups according to the medication type. The impact of ADHD on dental age difference (the difference between dental age and chronologic age) was analyzed using T-test and the association between medication type and dental age difference was analyzed through one way ANOVA. Results: The mean difference between estimated dental age and chronologic age (dental age difference) for all subjects was 0.80 years. There was no significant dental age difference in subjects with ADHD and the control group (0.78±1.28vs. 0.84 ±1.09 years respectively; P=0.75) and there was no significant difference in dental age difference and type of medication (P=0.84). Conclusion: No significant difference was found between children with ADHD and unaffected children with respect to dental age difference. No significant differences were found in dental age difference in the four medication groups.

scholarly journals The curative effect analysis of peripherally inserted central venous catheter catheterization for tumor patients under the guidance of new medical guide wire

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Weizhu Xiao
Keyword(s):  
Success Rate ◽  
Guide Wire ◽  
Venous Catheter ◽  
General Information ◽  
Control Group ◽  
Observation Group ◽  
Curative Effect ◽  
Effect Analysis ◽  
Significant Difference ◽  
The Difference

Abstract Objective To report a method of PICC catheterization with the aid of a new medical guide wire, and to discuss the curative effect. Methods Five hundred and thirteen patients who visited our hospital from January 2013 to December 2019 for PICC catheterization were selected as study subjects. Random number method was used to group patients. General information was recorded for both groups. Patients in the observation group received catheterization with the aid of a new medical guide wire. The control group received catheterization via conventional guide wire. The success rate of the first catheterization, the success rate of the catheterization, the timing of the catheterization, the complications and the position of the catheter end were compared between the two groups. Results There was no significant difference in general information between the two groups. After analyzing the puncture situation of the two groups, it was found that the average catheterization time of the observation group was shorter than that of the control group, and the difference was statistically significant. Patients in the observation group had higher success rate of one-time catheterization and catheterization success rate, and the difference was statistically significant. The incidences of occult thrombosis, phlebitis and catheter blockage in the observation group were lower than those in the control group, and the difference was statistically significant. The incidence of dominant thrombosis and bleeding at puncture point in the observation group was also lower than that in the control group, but the difference was not statistically significant. Conclusion The new type of medical guide wire component is effective for PICC catheterization and worthy of further promotion.

scholarly journals Effects of Crown Lengthening on Bi, PLI and PD Levels in Patients with Different Periodontal Biotypes

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Lu Bai
Keyword(s):  
Plaque Index ◽  
Control Group ◽  
Observation Group ◽  
Gingival Margin ◽  
Probing Depth ◽  
Flat Type ◽  
Significant Difference ◽  
The Difference ◽  
Periodontal Probing ◽  
Crown Lengthening

Objective: To investigate the effect of crown lengthening on patients with different periodontal biological types. Methods: 60 patients with different periodontal biotypes treated in our hospital from May 2017 to February 2019 were retrospectively analyzed. According to the different periodontal biotypes, the above-mentioned patients were further divided into control group (thin fan type, 30 cases) and observation group (thick flat type, 30 cases).The periodontal probing depth (PD), plaque index (PLI), bleeding index (BI) and gingival margin position at 1 week, 1 month, 2 months and 3 months after operation were compared between the two groups. Results: The PD, Bi and PLI values of the two groups after treatment were lower than those before treatment (P<0.05);There was no significant difference in gingival margin position between the two groups after 1 week to 1 month and 1 month to 2 months (P>0.05);After 2 months to 3 months of treatment, the gingival margin distance of the observation group was larger than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: Crown lengthening can effectively improve the periodontal indexes of different periodontal biotypes, and the gingival margin of thick and flat type patients moves more toward the crown.

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