scholarly journals Seasonal and Climatic Variation in the Incidence of Adult Acute Appendicitis: A Seven Year Longitudinal Analysis

2020 ◽  
Author(s):  
Thomas York

Abstract Introduction Acute appendicitis represents an extremely common surgical emergency, yet its aetiology remains uncertain. A multifactorial understanding of its causation has emerged along with increasing evidence of seasonal variation. This study seeks to find evidence for such a circannual trend within the UK, and further assess key meteorological indicators which may be causative of any such variation. Methods The patient records of a region health body in the North East of England were retrospectively assessed over a 7-year period. Incidence of acute appendicitis was recorded and averaged by month before undergoing statistical analysis for variation and correlation with average temperature, sunlight hours, and rainfall. Results The incidence of acute appendicitis revealed significant seasonal variation with only 38 total cases in the months of January compared to 73 in July, a 92.1% increase. Only a weak correlation was seen between incidence and average sunlight hours/rainfall, however a significant, positive correlation was found between incidence and average temperature ( r=0.58, p=0.48 ). Conclusion Compelling evidence is found to support the existence of a circannual trend for acute appendicitis. Data suggests a seasonal peak in the month of July, accompanied by a low in January, a finding that develops the understanding of this trend from previously equivocal research in the UK.

2019 ◽  
Author(s):  
Fang Wang ◽  
Dingtao Hu ◽  
Xiaoqi Lou ◽  
Nana Meng ◽  
Qiaomei Xie ◽  
...  

Abstract Background: The outcomes of smoking have generated considerable clinical interest in recent years. Although people from different countries are more interested to the topic of quit smoking during the winter, few studies have tested this hypothesis. The current study aimed to quantify public interest in quit smoking via Google.Methods: We use Google Trends to obtain the Internet search query volume for terms relating to quit smoking for major northern and southern hemisphere countries in this research. Normally search volumes for the term “quit smoking + stop smoking + smoking cessation” were retrieved within the USA, the UK, Canada, Ireland, New Zealand and Australia from January 2004 to December 2018. Seasonal effects were investigated using cosinor analysis and seasonal decomposition of time series models.Results: Significant seasonal variation patterns in those search terms were revealed by cosinor analysis and demonstrated by the evidence from Google Trends analysis in the representative countries including the USA (pcos = 2.36×10-7), the UK (pcos < 2.00×10-16), Canada (pcos < 2.00×10-16), Ireland (pcos <2.00×10-16) ,Australia (pcos = 5.13×10-6) and New Zealand (pcos = 4.87×10-7). Time series plots emphasized the consistency of seasonal trends with peaks in winter / late autumn by repeating in nearly all years. The overall trend of search volumes, observed by dynamic series analysis, declined from 2004 to 2018.Conclusions: The preliminary evidence from Google Trends search tool showed a significant seasonal variation and decreasing trend for the RSV of quit smoking. Our novel findings in smoking cessation epidemiology need to be verified with further studies, and the mechanisms underlying these findings must be clarified.


Finisterra ◽  
2012 ◽  
Vol 31 (62) ◽  
Author(s):  
Andrew Pike ◽  
Mário Vale

The industrial policy in the UK and in Portugal, as in most EU countries, seeks to attract new investment capacity, to create jobs and to promote the impact of the so-called "demonstration efect" of "greenfield" development strategies pursued in the new plants of inward investors on existing or "brownfield" plants. This industrial policy focus is particularly evident in the automobile industry.This paper compares the industrial policy oriented towards the automobile industry in the UK and in Portugal. Two recent "greenfield" investments are analised: Nissan in the North-East region (UK) and Ford/VW in the Setúbal Peninsula (Portugal), as well as three "brownfield" plants: Ford Halewood and GM Vauxhall Ellesmere Port in the North-West region (UK) and Renault in Setúbal (Portugal). The first part starts with a discussion of industrial policy in the automobile sector, the role of "greenfield" development strategies and the "demonstration effect" on "brownfield" plants. Then, the limits of new inward investment are pointed out, basically their problems and restrictions. Afterwards, the structural barriers to the "demonstration effect" within "brownfield" plants are outlined and some possabilities for alternative "brownfield" development strategies are presented.


1997 ◽  
Vol 42 (1) ◽  
pp. 13-15 ◽  
Author(s):  
D. Nathwani ◽  
J Spiteri

Malaria remains a huge public health problem worldwide, with over 100 million new cases annually, causing one to two million deaths.1 This global problem spills over into the UK, with around 2000 cases of reported annually.2 The proportion of infections due to Plasmodium falciparum (PF) continues to increase and worse still accounts for five to 12 deaths per year. In 1992, Nathwani et al reported the 10 year experience of malaria cases admitted to the Regional Infection Unit, in Aberdeen, Scotland-the “Oil Capital”.3 This study was of interest in that 46% of those British residents who acquired infection had travelled to West or Central Africa on oil related business. The Oil boom of the 1980‘ s appeared to very much centred around Aberdeen and the neighbouring hinterland but did not appear to extend to Dundee which was only 60 miles further down the North-East coast. We, therefore, carried out a retrospective study of patients with malaria admitted to the Regional Infectious Diseases Unit in Dundee over a fifteen year period between 1980 and 1994.


2020 ◽  
pp. bmjspcare-2020-002422
Author(s):  
Donna Wakefield ◽  
Elizabeth Fleming ◽  
Kate Howorth ◽  
Kerry Waterfield ◽  
Emily Kavanagh ◽  
...  

ObjectivesNational guidance recommends equality in access to bereavement services; despite this, awareness and availability appears inconsistent. The aim of this study was to explore availability and accessibility of bereavement services across the North-East of England and to highlight issues potentially applicable across the UK, at a time of unprecedented need due to the impact of COVID-19.MethodsPhase 1: an eight item, web-based survey was produced. A survey link was cascaded to all GP practices (General Practitioners) in the region. Phase 2: an email was sent to all services identified in phase 1, requesting details such as referral criteria and waiting times.ResultsAll 392 GP practices in the region were invited to participate. The response rate was 22% (85/392). Twenty-one per cent (18/85) of respondents reported that they do not refer patients, comments included ‘not aware of any services locally’. A total of 36 services were contacted with 72% responding with further information. Most bereavement specific support was reliant on charity-funded services including hospices, this sometimes required a pre-existing link with the hospice. Waiting times were up to 4 months.ConclusionsAlthough multiple different, usually charity-funded services were identified, awareness and accessibility were variable. This survey was conducted prior to the COVID-19 pandemic, where complex situations surrounding death is likely to impact on the usual grieving process and increase the need for bereavement support. Meanwhile, charities providing this support are under severe financial strain. There is an urgent need to bridge the gap between need and access to bereavement services.


2019 ◽  
Vol 8 (3) ◽  
pp. e000409 ◽  
Author(s):  
Julia Wood ◽  
Bob Brown ◽  
Annette Bartley ◽  
Andreia Margarida Batista Custódio Cavaco ◽  
Anthony Paul Roberts ◽  
...  

In the UK, over 700 000 patients are affected by pressure ulcers each year, and 180 000 of those are newly acquired each year. The occurrence of pressure ulcers costs the National Health Service (NHS) more than 3.8 million every day. In 2004, pressure ulcers were estimated to cost the NHS £1.4–£2.4 billion per year, which was 4% of the total NHS expenditure.The impact on patients can be considerable, due to increased pain, length of hospital stay and decreased quality of life. However, it is acknowledged that a significant number of these are avoidable.In early 2015, it was identified that for the North East and North Cumbria region the incidence of pressure ulcers was higher than the national average. Because of this, a 2-year Pressure Ulcer Collaborative was implemented, involving secondary care, community services, care homes and the ambulance service, with the aim of reducing the percentage of pressure ulcers developed by patients within their care.The Breakthrough Series Collaborative Model from the Institute for Healthcare Improvement provided the framework for this Collaborative.In year 1, pressure ulcers were reduced by 36%, and in year 2 by 33%, demonstrating an estimated cost saving during the lifespan of the Collaborative of £513 000, and a reduction in the number of bed days between 220 and 352.


2016 ◽  
Vol 17 (S1) ◽  
pp. 13-20 ◽  
Author(s):  
Simon Deakin

In the aftermath of the Brexit referendum of 23 June 2016, the question of migration has been at the forefront of attempts to understand what happened, and in particular why working class communities in many of the regions of England, and in parts of Wales, voted predominantly for the Leave side. Polling data show a weak correlation between areas of the country that voted for Leave and high levels of inward migration from the rest of the EU. The link between immigration and Brexit is very clear in East Anglian agricultural towns like Boston and Wisbech, but otherwise is weak. South Wales and the North East of England, which also saw clear majorities for Leave, are not areas of high EU migration. Instead, they are regions that have experienced successive waves of deindustrialisation since the 1980s. The overriding issue raised by the Brexit vote, in my view, is not migration as such (although that is part of the story), but a wider phenomenon of deepening economic insecurity, and the dangerous political dynamic it has created.


2014 ◽  
Vol 43 (2) ◽  
pp. 311-330 ◽  
Author(s):  
KAYLEIGH GARTHWAITE ◽  
CLARE BAMBRA ◽  
JONATHAN WARREN ◽  
ADETAYO KASIM ◽  
GRAEME GREIG

AbstractThe UK social security safety net for those who are out of work due to ill health or disability has experienced significant change, most notably the abolition of Incapacity Benefit (IB) and the introduction of Employment and Support Allowance (ESA). These changes have been underpinned by the assumption that many recipients are not sufficiently sick or disabled to ‘deserve’ welfare benefits – claims that have been made in the absence of empirical data on the health of recipients. Employing a unique longitudinal and mixed-methods approach, this paper explores the health of a cohort of 229 long-term IB recipients in the North East of England over an eighteen-month period, during a time of significant changes to the UK welfare state. In-depth interviews with twenty-five of the survey cohort are also presented to illustrate the lived experiences of recipients. Contributing to debates surrounding the conceptualisation of work-readiness for sick and disabled people, findings indicate IB recipients had significantly worse health than the general population, with little change in their health state over the eighteen-month study period. Qualitative data reinforced the constancy of ill health for IB recipients. Finally, the paper discusses the implications for social policy, noting how the changing nature of administrative definitions and redefinitions of illness and capacity to work can impact upon the lives of sick and disabled people.


Author(s):  
E.S. Fileman ◽  
R.J.G. Leakey

Microzooplankton community composition, abundance, biomass and grazing impact were assessed, along with measurements of ciliate growth and mortality, during the onset of the spring bloom in the north-east Atlantic. The study was undertaken as part of the UK Biogeochemical Ocean Flux Study during 1 May to 15 June 1990. The microzooplankton community was composed of protozoans and metazoan developmental stages with respective mixed-layer depth integrated biomass values ranging from 127 to 638 and 74 to 394 mg C m−2. High numbers of aloricate ciliates (up to 35,000 cells l−1) dominated the microzooplankton community during early May prior to the onset of the spring bloom. Ciliate abundance then declined rapidly during mid-May with community growth rates ranging from −0·71 to 0·23 d−1. High abundances of metazoplankton (up to 400 l−1) were also recorded at this time and may have contributed to the decline in ciliate numbers. In late May and early June the protozoan community comprised a more even mix of dinoflagellates, tintinnids and aloricate ciliates. Phytoplankton mortality rates, measured using a dilution technique, ranged from 0·2 to 0·5 d−1. The microzooplankton consumed 8 to 44 μg C l−1 d−1, equivalent to between 16 and 40% of the chlorophyll biomass and 38 and 154% of primary production. These high rates of herbivory reflect the predominance of small (<5 μm in length) phytoplankton cells present throughout the first half of the study and support previous studies demonstrating the microzooplankton to be the main grazers of phytoplankton in the north-east Atlantic. However, there is also evidence that a disparity between predator and prey may have prevented a response by the microzooplankton to rapid increases in phytoplankton biomass and production during the spring bloom.


1960 ◽  
Vol 38 (10) ◽  
pp. 1366-1375 ◽  
Author(s):  
J. A. Kim ◽  
B. W. Currie

A previous paper showed that systematic motions of aurora parallel and normal to the geomagnetic meridians could be deduced from successions of all-sky camera photographs. More reliable deductions which are based on a much larger number of observations, including some from a station inside the auroral zone, are reported in this paper. Both southward and northward speeds increase with geomagnetic latitude to the auroral zone where they become constant, or even decrease slightly, before continuing to increase inside the auroral zone. A seasonal variation of north–south speeds does not appear to exist. A diurnal variation of north–south speeds, dependent on geomagnetic latitude, is evident, the speeds decreasing to a minimum during the morning hours to the south of the auroral zone and increasing to a maximum during the same hours to the north of the zone. Large positive correlations exist between north–south speeds and departures of the magnetic field intensity from normal. East–west speeds either decrease or remain constant with increasing geomagnetic latitude. A significant seasonal variation of east–west speeds is not evident. Eastward speeds are at a maximum between 03 and 04 hours L.M.T., and are associated with negative magnetic bays; westward speeds, between 21 and 22 hours L.M.T., and are associated with positive magnetic bays.


Author(s):  
Peter van der Graaf ◽  
Mandy Cheetham ◽  
Amelia Lake ◽  
Mark Welford ◽  
Rosemary Rushmer ◽  
...  

Background: Fuse was established in 2008 as one of five public health research centres of excellence in the UK funded by the UK Clinical Research Centres collaboration. The centre works across five universities in the North East of England. This is an innovative collaboration and enables the pooling of research expertise. A prime focus of the centre is not just the production of excellent research, but also its translation into usable evidence, a dual focus that remains uncommon.Aims/objectives: This practice paper outlines Fuse’s approach to knowledge exchange (KE) by reflecting on ten years of collaborative research between academics and policy and practice partners in the North East of England. We will describe the principles and assumption underlying our approach and outline a conceptual model of four steps in Fuse’s KE process to develop collaborative research and achieve meaningful impact on policy and practice.Key conclusions: Our model describes a fluid and dynamic approach to knowledge exchange broken down in four steps in the KE process that are concurrent, iterative and vary in intensity over time: awareness raising; knowledge sharing; making evidence fit for purpose; and supporting uptake and implementation of evidence. These steps support the relational context of KE. Relationship building and maintenance is essential for all stages of KE to develop trust and explore the meaning and usefulness of evidence in a multi-directional information flow that supports the co-creating and application of evidence.


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