Antioxidant Evaluation and Chemo-Profiling of Non-conventional Curcuma Species as Conservation of Drug Targeting Molecule
Abstract The objective of the present study was to determine and compare antioxidant activities of different species of Curcuma i.e. Curcuma longa, Curcuma caesia and Curcuma aromatic and their chemoprofiling for conservation of highest yield plants. The functional group analysis of the plants extract were determined by FTIR and structural features of phyto-constituents and Chemo-profiling of ethanol fractions of all targeted Curcuma species showing highest activity were analyzed by GC–MS/MS. Ethanolic extract of C. aromatica (ECA) was exhibited to determine high radical scavenging activity against DPPH (92.12%), lipid Peroxidation (85.13 ± 0.23%), nitric oxide scavenging, total reducing power (700.83 ± 8.14 μg/mg) and ferric reducing power assay. In ABTS·+ and phosphomolybdate assay Curcuma species showed a significant difference ranging from 67.53 – 98.57%. Furthermore, the amount of total phenolic and flavonoid content ranged from 3.63± 1.06 – 545.77 ± 2.76 μg/mg eq GAE and 21.18 –101.29 μg/mg eq QUE respectively. The results indicated that the ethanolic extracts showed highest in vitro antioxidant activity. It can be conclude from the study that Curcuma species may serve as an important bioresource as an antioxidant drug.