scholarly journals Giant Intramuscular Lipoma of Biceps Brachii – A Rare Case Report

2021 ◽  
Author(s):  
Saifullah Nizam ◽  
Dinesh Kardam ◽  
Raghav Yelamanchi ◽  
Udit Khurana
Keyword(s):  
Biceps Brachii ◽  
Soft Tissue Tumors ◽  
Interesting Case ◽  
Uneventful Recovery ◽  
Mesenchymal Tumors ◽  
Primary Tumors ◽  
Left Elbow ◽  
Intramuscular Lipoma ◽  
Rare Case Report ◽  
Giant Lipoma

Abstract Lipomas are benign mesenchymal tumors. They are the most common type of soft tissue tumors. Intramuscular lipoma is a relatively uncommon condition and accounts for about1.8% of all primary tumors of adipose tissue and are relatively rare in upper extremity. When deep, large and unusual in location, magnetic resonance imaging (MRI) can identify and localise these tumours and is the best modality to differentiate lipoma and liposarcoma. We report an extremely rare and interesting case of giant intramuscular biceps brachii lipoma. A 22-year male patient presented with insidious onset, firm and non-tender swelling in the left elbow without any distal neurovascular deficits. MRI and biopsy were suggestive of lipoma. Wide local excision was done and patient had an uneventful recovery. Post-operative histopathology was suggestive of lipoma. To conclude, intramuscular giant lipoma of biceps brachii is an infrequent clinical entity due to its location. Imaging is necessary to differentiate it from its malignant counterpart and to plan surgical management.

scholarly journals Giant Intramuscular Lipoma Otot Biceps Brachii

2017 ◽  
Vol 2 (2) ◽  
pp. 79-83
Author(s):  
Eristan N. Napitupulu ◽  
Bambang Supriyadi ◽  
Yana Supriatna
Keyword(s):  
Soft Tissue ◽  
Ct Scan ◽  
Signal Intensity ◽  
Biceps Brachii ◽  
Soft Tissue Mass ◽  
Biceps Brachii Muscle ◽  
Tissue Mass ◽  
Primary Tumors ◽  
Intramuscular Lipoma ◽  
Giant Lipoma

Intramuscular lipoma is a relatively uncommon condition and accounts for just 1,8% of all primary tumors of adipose tissue and less than 1% of all lipoma. This tumor arises within skeletal muscle fibers at various locations. However, giant intramuscular lipomas of biceps brachii muscle are rare tumors. A 48-years old man presented with a mass on his right upper-arm. The mass existed for one year and has since increased in size. On physical examination, the mass was pain upon palpation and completely mobile. Plain radiography, the soft tissue mass unremarkable. Computed tomography (CT) scan revealed a hypodense mass situated within right biceps brachii muscle with -72 until -83 Hounsfield. Magnetic resonance imaging (MRI), the mass was found inside of biceps brachii muscle. In T1- and T2- weighted images, the lesion area demonstrated high signal intensity, and SPAIR showed signal suppression similar to normal fat. The patient underwent radical excision of the lesion, which was found to be greater than 12 cm in size. Final pathology revealed intramuscular lipoma. A lipoma of greater than 5 cm is classified as a giant lipoma. Giant lipoma in the upper extremities and involving biceps brachii muscle are rare. The plain radiographs may either be unremarkable or may demonstrate a radiolucent soft tissue mass of fat opacity. On CT and MRI, the lipoma appears as an non-invasive mass with homogenous fat signal intensity. The main differential diagnosis of intramuscular lipomas is well-differentiated liposarcomas. The proper management is open excision. The pathological report is vital to confirm the diagnosis. We reported a rare case of giant intramuscular lipoma of biceps brachii who was successfully opened excision at our institute. CT scan and MRI can identify and localize these tumours, and facilitate the operative planning

scholarly journals Primary Adrenal Leiomyosarcoma in an Arab Male: A Rare Case Report with Immunohistochemistry Study

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Veena Nagaraj ◽  
Mohammed Mustafa ◽  
Essa Amin ◽  
Waleed Ali ◽  
Shamil Naji Sarsam ◽  
...  
Keyword(s):  
The Body ◽  
Biological Behavior ◽  
Renal Neoplasm ◽  
Tumor Type ◽  
Mesenchymal Tumors ◽  
Rare Form ◽  
Radiological Investigation ◽  
Primary Tumors ◽  
Rare Case Report ◽  
Rule Out

Primary adrenal leiomyosarcoma is a rare form of adrenal mesenchymal tumors. Immunohistochemistry (IHC) together with histology takes a major role in determining the tumor type and predicting their biological behavior and differentiating them from adrenal cortical carcinoma. Appropriate radiological investigation is necessary to rule out metastatic disease from primary tumors elsewhere in the body. In this case, we report a primary leiomyosarcoma of the adrenal gland in a 61-year-old Bahraini male clinically presumed to be a renal neoplasm.

Diagnostic Value of Electron Microscopy in Soft Tissue Tumors

1970 ◽  
Vol 28 ◽  
pp. 220-221
Author(s):  
Gerald Fine ◽  
Azorides R. Morales
Keyword(s):  
Cardiac Myxoma ◽  
Osteogenic Sarcoma ◽  
Diagnostic Value ◽  
Soft Tissue Tumors ◽  
Amelanotic Melanoma ◽  
Growth Patterns ◽  
Light Microscopic Level ◽  
Mesenchymal Tumors ◽  
Good Agreement

For years the separation of carcinoma and sarcoma and the subclassification of sarcomas has been based on the appearance of the tumor cells and their microscopic growth pattern and information derived from certain histochemical and special stains. Although this method of study has produced good agreement among pathologists in the separation of carcinoma from sarcoma, it has given less uniform results in the subclassification of sarcomas. There remain examples of neoplasms of different histogenesis, the classification of which is questionable because of similar cytologic and growth patterns at the light microscopic level; i.e. amelanotic melanoma versus carcinoma and occasionally sarcoma, sarcomas with an epithelial pattern of growth simulating carcinoma, histologically similar mesenchymal tumors of different histogenesis (histiocytoma versus rhabdomyosarcoma, lytic osteogenic sarcoma versus rhabdomyosarcoma), and myxomatous mesenchymal tumors of diverse histogenesis (myxoid rhabdo and liposarcomas, cardiac myxoma, myxoid neurofibroma, etc.)

scholarly journals FOXO1 gene involvement in a non-rhabdomyosarcomatous neoplasm

2021 ◽  
Author(s):  
Simon Haefliger ◽  
Muriel Genevay ◽  
Michel Bihl ◽  
Romina Marone ◽  
Daniel Baumhoer ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Soft Tissue ◽  
Genetic Heterogeneity ◽  
Gene Fusion ◽  
Fusion Gene ◽  
Soft Tissue Tumors ◽  
Gene Fusions ◽  
Mesenchymal Tumors ◽  
Myoepithelial Differentiation ◽  
Foxo1 Gene

AbstractMyoepithelial neoplasms of soft tissue are rare tumors with clinical, morphological, immunohistochemical, and genetic heterogeneity. The morphological spectrum of these tumors is broad, and the diagnosis often requires immunostaining to confirm myoepithelial differentiation. Rarely, tumors show a morphology that is typical for myoepithelial neoplasms, while the immunophenotype fails to confirm myoepithelial differentiation. For such lesions, the term “myoepithelioma-like” tumor was introduced. Recently, two cases of myoepithelioma-like tumors of the hands and one case of the foot were described with previously never reported OGT-FOXO gene fusions. Here, we report a 50-year-old woman, with a myoepithelial-like tumor localized in the soft tissue of the forearm and carrying a OGT-FOXO1 fusion gene. Our findings extend the spectrum of mesenchymal tumors involving members of the FOXO family of transcription factors and point to the existence of a family of soft tissue tumors that carry the gene fusion of the OGT-FOXO family.

NECROTISING SOFT TISSUE INFECTION OF BILATERAL UPPER LIMB CAUSED BY THE INJECTION OF ORAL BACTERIA: A CASE REPORT

Hand Surgery ◽  
2013 ◽  
Vol 18 (02) ◽  
pp. 243-246 ◽  
Author(s):  
Yuichi Yoshii ◽  
Tomoo Ishii ◽  
Shinsuke Sakai
Keyword(s):  
Soft Tissue ◽  
Upper Limb ◽  
Soft Tissue Infection ◽  
Soft Tissues ◽  
Biceps Brachii ◽  
Subcutaneous Tissue ◽  
Oral Bacteria ◽  
Tissue Infection ◽  
Left Elbow ◽  
The Right

Necrotising soft tissue infection is a rare and rapid process with devastating consequence. We report one case of necrotising soft tissue infection in a bilateral upper limb with uncommon oral bacteria. Radiological imaging revealed the presence of gas in upper limb soft tissues, and an MRI showed the localised signal changes in the biceps muscle of the right upper arm, and the subcutaneous tissue of the left elbow. The patient was treated with surgical resection of the infected muscle and wide debridement of the subcutaneous tissue. Antibiotics were initiated. The patient recovered immediately without functional deficit. The unique features of this patient were possible to observe in the progression of the necrotising soft tissue infection in the bilateral upper limb with intentional injection of oral bacteria, and the effect of biceps brachii resection in a prime age worker.

scholarly journals Gingival Lipoma: A Rare Case Report

2017 ◽  
Vol 1 (1) ◽  
pp. 37-39
Author(s):  
Sweta Shrestha ◽  
Shaili Pradhan ◽  
Ranjita Shrestha Gorkhali
Keyword(s):  
Rare Case ◽  
Surgical Excision ◽  
Soft Tissue Tumors ◽  
Rare Case Report ◽  
Postsurgical Complication ◽  
Benign Tumours ◽  
One Year ◽  
Slow Growing ◽  
Oral Soft Tissue

Lipomas are benign tumours of mesenchymal origin (mature adipocytes) that are comparatively uncommon in the oral cavity corresponding to less than 4.4% of all benign oral soft tissue tumors. Clinically, they present as slow growing, soft, asymptomatic masses. Histopathologically, they appear as thinly encapsulated lesion composed of mature adipocytes with inconspicuous vascularity. The pathogenetic mechanisms of oral lipomas are still unclear. They are usually treated by surgical excision and bear excellent prognosis. Here we report a case of intraoral lipoma in 54 year old male patient in the left lower lingual alveolar mucosal region that was treated by surgical excision using electrocautery without any postsurgical complication. One-year follow-up showed no evidence of recurrence.

scholarly journals Case Reports in Oncological Medicine Myoepithelioma: A New Rearrangement Involving the LPP Locus in a Case of Multiple Bone and Soft Tissue Lesions

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Géraldine Pairet ◽  
Gaëlle Tilman ◽  
Rafaël Sciot ◽  
Thomas Schubert ◽  
Vasiliki Perlepe ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Protein Expression ◽  
Case Reports ◽  
S100 Protein ◽  
Soft Tissue Tumors ◽  
Molecular Karyotyping ◽  
Genomic Alteration ◽  
Navicular Bone ◽  
Mesenchymal Tumors ◽  
Epithelial Markers

We report a case of multiple myoepithelioma with synchronous bone and soft tissue tumors, associated with a new genomic alteration of the LPP locus. The lesions occurred in the foot by presenting one lump in the plantar soft tissue, and three lesions were detected in the calcaneus and in the navicular bone. All tumors showed the double immunophenotype of epithelial markers and S100 protein expression. No rearrangement of the EWSR1 and FUS loci was detected as reported in myoepitheliomas. However, molecular karyotyping detected an unbalanced rearrangement of the LPP locus, not involving the HMGA2 locus, which is the most frequent translocation partner observed in benign mesenchymal tumors such as lipomas (of soft tissue as well as parosteal) and pulmonary chondroid hamartoma.

scholarly journals Intracranial Myxoid Mesenchymal Tumor/Myxoid Subtype Angiomatous Fibrous Histiocytoma: Diagnostic and Prognostic Challenges

Neurosurgery ◽  
2020 ◽  
Vol 88 (1) ◽  
pp. E114-E122
Author(s):  
Ricardo A Domingo ◽  
Tito Vivas-Buitrago ◽  
Mark Jentoft ◽  
Alfredo Quinones-Hinojosa
Keyword(s):  
Vasogenic Edema ◽  
Camp Response Element Binding ◽  
Soft Tissue Tumors ◽  
Mesenchymal Tumor ◽  
Mesenchymal Tumors ◽  
Camp Response Element ◽  
Radiographic Evidence ◽  
Clinical Behavior ◽  
Element Binding Protein ◽  
Middle Aged Adults

ABSTRACT BACKGROUND AND IMPORTANCE In the setting of intracranial neoplasms, EWSR1-cAMP Response Element-Binding Protein (CREB) transcription factor family fusions have been described in myxoid mesenchymal tumors, extremely rare entities with a close histopathologic and immunologic resemblance to myxoid subtype angiomatoid fibrous histiocytomas (AFH). Controversy exists on whether these central nervous system lesions are a subtype of myxoid AFH or a completely separate entity, which entitles a distinct clinical behavior and, consequently, a different approach to management. Upon review of the literature, only 14 cases of intracranial tumors harboring an EWSR1-CREB family fusion were identified, with only 3 cases presenting in middle-aged adults, none of which reported an EWSR1-CREM fusion mutation. Significant variability in reported radiographic and histopathological characteristics, as well as in clinical outcomes, was noted. Their similarity with other soft tissue tumors, added to the scarce information on its clinical behavior, represents a great diagnostic and therapeutic challenge to the treating physician. CLINICAL PRESENTATION We present a rare case of EWSR1-CREM mutated intracranial myxoid mesenchymal tumor/myxoid subtype AFH presenting as persistent headaches in a 36-yr-old woman with radiographic evidence of rapid growth and extensive vasogenic edema, for which she underwent surgical resection. CONCLUSION This represents a unique case of EWSR1-CREM mutated intracranial myxoid mesenchymal tumor presenting in adulthood, with evidence of aggressive behavior.

scholarly journals Intramuscular lipoma: a review of the literature

2014 ◽  
Vol 6 (4) ◽  
Author(s):  
Shane McTighe ◽  
Ivan Chernev
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
Clinical Features ◽  
Common Type ◽  
Fatty Tissue ◽  
Review Of The Literature ◽  
Mesenchymal Tumors ◽  
Intramuscular Lipoma ◽  
Imaging Characteristics ◽  
Well Differentiated

Lipomas are the most common type of soft tissue mesenchymal tumors. They are typically located subcutaneously and consist of mature fatty tissue. When they occur under the enclosing fascia, they are called deep-seated lipomas. Infrequently, lipomas can arise inside the muscle and are called intramuscular lipomas. Intramuscular lipomas have been commonly investigated and categorized in the same group as other deep-seated and superficial lipomatous lesions. Their clinical, histological and imaging characteristics may resemble well-differentiated liposarcomas, further adding to the difficulties in the differential diagnosis. This article summarizes the available literature and describes the typical epidemiological, pathological and clinical features of intramuscular lipomas, as well as delineating their treatment and prognosis.

scholarly journals Gastrointestinal stromal tumor presenting as ileo-ileal intussusception: a rare case report

2019 ◽  
Vol 6 (12) ◽  
pp. 4563
Author(s):  
Dheer S. Kalwaniya ◽  
M. Ranjith Kumar ◽  
M. Vignesh ◽  
Jaspreet S. Bajwa
Keyword(s):  
Gastrointestinal Stromal Tumors ◽  
Rare Case ◽  
Acute Intestinal Obstruction ◽  
Stromal Tumor ◽  
Elderly Male ◽  
Mesenchymal Tumors ◽  
Stromal Tumors ◽  
Uncommon Presentation ◽  
Rare Case Report ◽  
Sixth Decade

Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors that can arise in any part of gastrointestinal tract. It is commonly seen in the fifth or sixth decade of life with slight male preponderance.Intussusception and subsequent obstruction is a very uncommon presentation of these lesions because of their tendency to grow in an extraluminal fashion. In the literature, very few cases of small bowel intussusceptions from a stromal tumor in adults have been described. We report a rare case of GIST presenting as acute intestinal obstruction due to intussusception in an elderly male.

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