scholarly journals Postoperative cognitive recovery in children after both general and locoregional anesthesia and surgery

2020 ◽  
Author(s):  
Jalal El Hammoumi ◽  
Abdelkader Dahchour ◽  
Elmehdi Chhiti ◽  
Saïd Benlamkadem ◽  
Mohamed-Adnane Berdai ◽  
...  

Abstract Background and objectivesRecent researches have demonstrated that there is a progressive impairment in neurocognitive function following general anesthesia and surgery, and particularly, have evidenced that anesthetics impaired mechanisms of learning and memory, for days to months, in both adults and children.This study aimed to evaluate the influence of different types of anesthesia (General or Locoregional) on cognitive recovery by trial and error method, and also take into consideration other factors that would have an impact on the cognitive performance after anesthesia and surgery in children.MethodsIn the present cross-sectional study, 64 young children, aged between 10 and 15 years, have passed the CALM test (software based on trial and error method) 24h after their surgery, and the operating file filled by the anesthetist. The statistical analysis includes a descriptive part of our sample, a univariate, and multivariate analysis of the results of the CALM test and the various medical factors and lifestyles.Results and conclusionsThe cognitive performance of patients exposed to locoregional anesthesia (81.3%) was higher (p=0.01) when compared to patients under general anesthesia (34.4%). Both agitation (Neurological state) and postoperative pain significantly (p=0.02) altered the cognitive performance of patients. However, none of the other factors assessed such as gender, environmental living, schooling, pre-anesthetic consultation, and the type of intervention affects the postoperative cognitive performance of patients.Locoregional anesthesia has less effect on cognitive recovery when compared to general anesthesia. Both the postoperative pain and agitation alter cognitive performances of operated children.

2015 ◽  
Vol 62 (4) ◽  
pp. 140-152 ◽  
Author(s):  
Michelle Wong ◽  
Peter E. Copp ◽  
Daniel A. Haas

The objective of this study was to determine the prevalence, severity, and duration of postoperative pain in children undergoing general anesthesia for dentistry. This prospective cross-sectional study included 33 American Society of Anesthesiology (ASA) Class I and II children 4–6 years old requiring multiple dental procedures, including at least 1 extraction, and/or pulpectomy, and/or pulpotomy of the primary dentition. Exclusion criteria were children who were developmentally delayed, cognitively impaired, born prematurely, taking psychotropic medications, or recorded baseline pain or analgesic use. The primary outcome of pain was measured by parents using the validated Faces Pain Scale-Revised (FPS-R) and Parents' Postoperative Pain Measure (PPPM) during the first 72 hours at home. The results showed that moderate-to-severe postoperative pain, defined as FPS-R ≥ 6, was reported in 48.5% of children. The prevalence of moderate-to-severe pain was 29.0% by FPS-R and 40.0% by PPPM at 2 hours after discharge. Pain subsided over 3 days. Postoperative pain scores increased significantly from baseline (P < .001, Wilcoxon matched pairs signed rank test). Moderately good correlation between the 2 pain measures existed 2 and 12 hours from discharge (Spearman rhos correlation coefficients of 0.604 and 0.603, P < .005). In conclusion, children do experience moderate-to-severe pain postoperatively. Although parents successfully used pain scales, they infrequently administered analgesics.


Author(s):  
Lidiya Derbenyova

The article focuses on the problems of translation in the field of hermeneutics, understood as a methodology in the activity of an interpreter, the doctrine of the interpretation of texts, as a component of the transmission of information in a communicative aspect. The relevance of the study is caused by the special attention of modern linguistics to the under-researched issues of hermeneutics related to the problems of transmission of foreign language text semantics in translation. The process of translation in the aspect of hermeneutics is regarded as the optimum search and decision-making process, which corresponds to a specific set of functional criteria of translation, which can take many divergent forms. The translator carries out a number of specific translation activities: the choice of linguistic means and means of expression in the translation language, replacement and compensation of nonequivalent units. The search for the optimal solution itself is carried out using the “trial and error” method. The translator always acts as an interpreter. Within the boundaries of a individual utterance, it must be mentally reconstructed as conceptual situations, the mentally linguistic actions of the author, which are verbalized in this text.


Author(s):  
H. J. Godwin

The determination of a pair of fundamental units in a totally real cubic field involves two operations—finding a pair of independent units (i.e. such that neither is a power of the other) and from these a pair of fundamental units (i.e. a pair ε1; ε2 such that every unit of the field is of the form with rational integral m, n). The first operation may be accomplished by exploring regions of the integral lattice in which two conjugates are small or else by factorizing small primes and comparing different factorizations—a trial-and-error method, but often a quick one. The second operation is accomplished by obtaining inequalities which must be satisfied by a fundamental unit and its conjugates and finding whether or not a unit exists satisfying these inequalities. Recently Billevitch ((1), (2)) has given a method, of the nature of an extension of the first method mentioned above, which involves less work on the second operation but no less on the first.


2016 ◽  
Vol 4 (29) ◽  
pp. 11446-11452 ◽  
Author(s):  
Zhonglu Guo ◽  
Jian Zhou ◽  
Linggang Zhu ◽  
Zhimei Sun

Identifying suitable photocatalysts for photocatalytic water splitting to produce hydrogen fuelviasunlight is an arduous task by the traditional trial-and-error method.


2017 ◽  
Vol 5 (1) ◽  
pp. 23 ◽  
Author(s):  
Daniela Fernandes Tonholi ◽  
Gisele Oltramari

Aims: To determine the prevalence, cognitive performance and functionality of elderly people with Alzheimer's disease in long-stay institutions for the elderlyin the city of Bento Gonçalves. Methods: Cross-sectional study including 24 elderly residents in long-stay institutions for the elderly, sociodemographic datawere obtained, and the elderly were subjected to functional evaluation by the Functional Independence Measure and evaluation of cognitive performancethrough the mental state the Mini (MMSE). Results: Most of the residents were female (83%), as 54.2% schooling had completed junior high school, mostof the elderly (70.8%) was admitted by the will of the family, 100% of the elderly showed cognitive performance bad, and the smaller the more dependentcognitive performance was the individual. Conclusion: institutionalized elderly with Alzheimer's disease had negative results on cognitive performance,as well as deficits in their ability to perform activities of daily living, thus altering their functionality.Keywords: aging; functionality; cognition; Alzheimer Disease; long-stay institutions.


2009 ◽  
Vol 424 ◽  
pp. 197-204 ◽  
Author(s):  
W. Assaad ◽  
H.J.M. Geijselaers ◽  
K.E. Nilsen

The design of extrusion dies depends on the experience of the designer. After the die has been manufactured, it is tested during an extrusion process and machined several times until it works properly. The die is designed by a trial and error method which is expensive interms of time consumption and the amount of scrap. Research is going on to replace the trial pressing with finite element simulations that concentrate on material and tool analysis. In order to validate the tool simulations, an experiment is required for measuring the deformation of the die. Measuring the deformation of the die is faced with two main obstacles: high temperature and little free space. To overcome these obstacles a method is tried, which works by applying a laser beam on a reflecting surface. This cheap method is simple, robust and gives good results. This paper describes measuring the deformation of a flat die used to extrude a single U shape profile. In addition, finite element calculation of the die is performed. Finally, a comparison is performed between experimental and numerical results.


1969 ◽  
Vol 23 (2) ◽  
pp. 128-132 ◽  
Author(s):  
E. Alexander ◽  
B. S. Fraenkel

A routine method to adjust a grazing incidence spectrometer for maximum resolution is described. The trial and error method uses as variable, the distance of the slit from the Rowland circle. Examples of resolved doublets are shown.


2020 ◽  
Vol 6 (1) ◽  
pp. p1
Author(s):  
Shervin Assari ◽  
Shanika Boyce

Background: Due to a pattern known as Marginalization-related Diminished Returns (MDRs), historically oppressed non-Hispanic Black Americans show weaker effects of economic status on health and development, when compared to socially privileged non-Hispanic White Americans. Such MDRs are also documented for the effects of economic status on the school performance of non-Hispanic Black children. However, the existing knowledge is minimal on similar diminished returns on children’s intelligence. Aim: To compare racial and ethnic groups for the effect of subjective economic status on children’s cognitive performance, we compared non-Hispanic White and non-Hispanic Black children for the effects of subjective economic status on children’s matrix reasoning. Methods: This cross-sectional study included 7898 children from the Adolescent Brain Cognitive Development (ABCD) study. The predictor variable was subjective economic status, which was treated as a continuous measure. The primary outcome was children’s matrix reasoning, a domain of cognitive performance, measured by the Wechsler Intelligence Scales for Children-IV (WISC-V) matrix reasoning total score. Results: Overall, high subjective economic status was associated with higher matrix reasoning score. Race showed a statistically significant interaction with subjective economic status on children’s matrix reasoning score. This interaction suggested that high subjective economic status has a smaller boosting effect on increasing matrix reasoning score for non-Hispanic Black children relative to non-Hispanic White children. Conclusion: The degree by which subjective economic status correlates with matrix reasoning score, an important domain of cognitive performance, depends on race and racialization. Non-Hispanic Black children may show weaker gains in matrix reasoning from their subjective economic status than their non-Hispanic White counterparts. To minimize the racial gap in cognitive performance, we need to address diminished returns that occur as a result of the racialization of racial and ethnic minority children. Not only should we equalize economic status, but also increase the marginal returns of economic status for racial minorities, particularly non-Hispanic Black families. Such efforts require public policies that go beyond access and also consider how we can empower non-Hispanic Black communities and families so they can more effectively leverage and utilize their economic resources to secure measurable and tangible outcomes. Structural and societal barriers such as residential and school segregation may hinder non-Hispanic Black children from receiving the full effects of their family-level economic status on a variety of outcomes, including their cognitive performance.


2021 ◽  
Author(s):  
Prantik Dutta ◽  
Arun Gande ◽  
Gopi Ram

In this letter, a non-reciprocal filter with enhanced directivity is analyzed methodically and the filter parameters are optimized using an evolutionary algorithm. The return loss, insertion loss, and isolation characteristics of the filter exhibit a trade-off that makes manual tuning a trial-and-error method. The veracity of the numerical modeling is conformed by designing a 150 MHz lumped element non-reciprocal bandpass filter based on the parameters extracted using an evolutionary algorithm based particle swarm optimization (PSO). The simulated and measured results comply well with the modeling and the results exhibit maximum directivity of 28.2 dB without degradation in insertion loss (1.1 dB) and return loss (16.2 dB) within the passband. The algorithm can be utilized in designing non-reciprocal filters having different center frequencies and bandwidths.


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