scholarly journals Different Outcomes of Three Localized Primary Gastric Amyloidosis Cases

2020 ◽  
Author(s):  
Xuemei Liu ◽  
Lianjun Di ◽  
Jiaxing Zhu ◽  
Xinglong Wu ◽  
Hongping Li ◽  
...  

Abstract Background: Localized primary gastric amyloidosis is a rare disorder characterized by the extracellular deposition of insoluble fibrillary protein confined to the stomach, which can mimic various diseases, including gastrointestinal stromal tumors, gastric cancer and ulcers in endoscopic examination. Case presentation: Here, we report a series of 3 cases of localized gastric amyloidosis mimicking gastric mucosa-associated lymphoid tissue (MALT) lymphoma by endoscopic examination that were evaluated over the past ten years in our hospital. The different times of detection of this rare disease resulted in three totally different outcomes, indicating the significant importance of the early detection, diagnosis and treatment of this rare disease. The difficulty of making an accurate diagnosis and differential diagnosis is highlighted, and this report may provide more clinical experience for the diagnosis of localized primary gastric amyloidosis.Conclusions: Localized gastric amyloidosis is a rare metabolic disease that can look like MALT lymphoma. Early detection, diagnosis and treatment of this rare disease results in an excellent prognosis.

Author(s):  
Toshikatsu Naito ◽  
Ryo Yuge ◽  
Shinji Tanaka ◽  
Rina Otani ◽  
Hiroki Kadota ◽  
...  

AbstractA 53-year-old woman visited a doctor and complained of chest discomfort after meals. Esophagogastroduodenoscopy showed multiple granular elevations in the gastric body. After biopsies from the elevations, she was diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma. Polymerase chain reaction also detected Helicobacter pylori and H. suis. Treatment to eradicate H. pylori and H. suis was successful. Endoscopic examination after the bacterial eradication treatment showed that multiple granular elevations remained in the gastric body; however, no lymphoma cells were found during histopathological examination. Thus, we reported a case of H. pylori-positive gastric MALT lymphoma with a unique morphology associated with H. suis superinfection.


Author(s):  
Min Woo Kim ◽  
Min Young Kwak ◽  
Jun Yong Choi ◽  
Dong Sik Chang

Laryngeal amyloidosis is a rare disorder characterized by localized amyloid deposition and carries an excellent prognosis. On the other hand, mucosa associated lymphoid tissue (MALT) lymphoma is the most common type of marginal zone lymphoma. MALT lymphoma has a poorer prognosis compared to laryngeal amyloidosis due to more frequent local recurrence, distant metastasis and malignant changes. Despite the differences, as both are found in the form of benign mass and have slow progression, accurate diagnosis is necessary. This report deals with the case of a patient with voice change accompanied by a mass, in which the initial biopsy did not include enough specimen for an accurate diagnosis. However, in the second attempt, an adequate sample was obtained, hence the final diagnosis of laryngeal MALT lymphoma. Based on our recent experience and a review of related literature, we report a case of laryngeal MALT lymphoma mimicking laryngeal amyloidosis.


2021 ◽  
Author(s):  
Yongrui Zhao ◽  
Ronghua Hu ◽  
Rui Wu ◽  
Jiankun Xu

Abstract Background: Primary non-dural central nervous system (CNS) mucosa-associated lymphoid tissue (MALT) lymphoma is a rare indolent B-cell lymphoma, with only a few reported cases worldwide. Case presentation: This report presents the treatment of MALT lymphoma developing in the midbrain. The patient received radiotherapy, and the tumour was in complete remission. We also reviewed the literature on brain parenchymal-based MALT lymphoma, including the clinical presentation, treatment options and outcomes.Conclusions: Although there is no consensus on the optimal treatment for this rare disease, patients can respond well when treated with radiotherapy alone.


2014 ◽  
Vol 33 (4) ◽  
pp. 217-220
Author(s):  
Carol L. Beck ◽  
Lori Baas Rubarth

Genetic testing has made diagnosis and treatment possible for many infants. With the addition of many new tests over the past few years, it is important to understand the clinical usefulness of each of these tests. Selecting the correct method of genetic testing assists in obtaining an accurate diagnosis and development of a plan of care for the infant.


1992 ◽  
Vol 13 (1) ◽  
pp. 25-31
Author(s):  
Dennis W. Vane

The discovery of an abdominal mass in a child alarms and concerns both parents and the physician. The diagnosis and treatment of these lesions have undergone significant changes during the past few years, and the physician understandably may have some doubts about an appropriate diagnostic evaluation. An improved outcome can be expected with early detection and prompt treatment. As is the case in evaluating all abdominal problems, a careful physical examination is critical and may obviate the need for further investigations. An accurate history is also important, but this often is clouded by information from parents or other historians who may not have all the data at their disposal. The child may be too young, may not remember the exact chronology and occurrence of events, or may be afraid to relate them. This is particularly true if the incident involved trauma related to an act forbidden by the parents. It is critical that the child be calm and relaxed to make the examination effective, often a nearly impossible feat. This occasionally can be accomplished with a few words from the examiner and the assurance that no pain will result from simple palpation. Patience often is rewarded with a good examination; however, should this approach fail, the physician may resort to sedation.


2013 ◽  
Vol 4 (2) ◽  
pp. 26-34 ◽  
Author(s):  
A V Chupin ◽  
P Yu Orehov ◽  
D P Lebedev ◽  
P Yu Parshin ◽  
V N Lesnyak ◽  
...  

Report and literature review of the rare disease – celiac trunk compression syndrome are presented. We discuss as typical manifestations of disease, and the most controversial aspects of the pathogenesis, diagnosis and treatment. We propose a diagnostic algorithm for early detection of the disease, and show that to achieve a good effect, may be required several stages of intervention. With the accumulation and codifying of experience it is possible to develop a more detailed indications to different types of surgery.


2018 ◽  
Vol 56 (4) ◽  
pp. 500-505 ◽  
Author(s):  
E. M. Agafonova ◽  
T. V. Dubinina ◽  
Sh. F. Erdes

The review analyzes the foreign and Russian literature published in the past 30 years and devoted to the diagnosis and treatment of coxitis in ankylosing spondylitis (AS). The results of previous works have revealed the high rate of hip joint injury (HJI) in AS, but it is still unclear which diagnostic technique is the most sensitive for the early detection of coxitis. The latter has been shown to serve as one of the predictors of early disability in patients. The most studied treatment for coxitis is now HJI endoprosthesis, for which indications and contraindications have been clearly developed, while the question of drug therapy remains open.


Endoscopy ◽  
2011 ◽  
Vol 43 (S 03) ◽  
Author(s):  
Jian Chen ◽  
Liang Zhong ◽  
Jie Liu

2020 ◽  
pp. 1-5
Author(s):  
Anton Stift ◽  
Kerstin Wimmer ◽  
Felix Harpain ◽  
Katharina Wöran ◽  
Thomas Mang ◽  
...  

Introduction: Congenital as well as acquired diseases may be responsible for the development of a megacolon. In adult patients, Clostridium difficile associated infection as well as late-onset of Morbus Hirschsprung disease are known to cause a megacolon. In addition, malignant as well as benign colorectal strictures may lead to intestinal dilatation. In case of an idiopathic megacolon, the underlying cause remains unclear. Case Presentation: We describe the case of a 44-year-old male patient suffering from a long history of chronic constipation. He presented himself with an obscurely dilated large intestine with bowel loops up to 17 centimeters in diameter. Radiological as well as endoscopic examination gave evidence of a spastic process in the sigmoid colon. The patient was treated with a subtotal colectomy and the intraoperative findings revealed a stenotic stricture in the sigmoid colon. Since the histological examination did not find a conclusive reason for the functional stenosis, an immunohistochemical staining was advised. This showed a decrease in interstitial cells of Cajal (ICC) in the stenotic part of the sigmoid colon. Discussion: This case report describes a patient with an idiopathic megacolon, where the underlying cause remained unclear until an immunohistochemical staining of the stenotic colon showed a substantial decrease of ICCs. Various pathologies leading to a megacolon are reviewed and discussed.


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