scholarly journals Human Ageing is Associated with More Rigid Concept Spaces

2020 ◽  
Author(s):  
Sean Devine ◽  
Cassandra Neumann ◽  
David Levari ◽  
Robert Wilson ◽  
Ben Eppinger

Abstract Prevalence-induced concept change describes a cognitive mechanism by which someone’s definition of a concept shifts as the prevalence of instances of that concept changes. The phenomenon has real-world implications because this sensitivity to environmental characteristics may lead to substantial biases in judgements. While prevalence-induced concept change has been established in young adults, it is unclear how it changes as a function of human ageing. In this cross-sectional study, we explore how prevalence-induced concept change affects older adults’ lower-level, perceptual, and higher-order, ethical, judgements. We find that older adults are less sensitive to prevalence-induced concept change than younger adults across domains. Using a combination of computational and experimental approaches, we demonstrate that these changes in judgements are sensitive to the pace with which the stimuli occur in the environment and are affected by the effort that subjects invest in order to make accurate decisions. Based on findings from three experiments we argue that older adults’ concept spaces are more rigid than those of younger adults. However, what appear as an age-related cognitive “deficit” may turn out to be beneficial because it makes older adults less susceptible to biases in judgments.  

2020 ◽  
Author(s):  
Sean Devine ◽  
Cassandra Neumann ◽  
David Levari ◽  
Robert C Wilson ◽  
Ben Eppinger

Prevalence-induced concept change describes a cognitive mechanism by which someone’s definition of a concept shifts as the prevalence of instances of that concept changes. While this phenomenon has been established in young adults, it is unclear how it affects older adults. In this study, we explore how prevalence-induced concept change affects older adults’ lower-level, perceptual, and higher-order, ethical, decision-making. We find that older adults are less sensitive to prevalence-induced concept change than younger adults across both domains. Using a combination of computational and experimental approaches, we demonstrate that these age-related changes in judgements are driven by differences in response times between young and old adults, reflecting the time-sensitive and motivation-dependent nature of concept change. Overall, we argue that older adults’ concept spaces may be less flexible than younger adults’ in a changing world, which can make the elderly less sensitive to biases in their judgement.


Author(s):  
Ernest K. Ofori ◽  
Savitha Subramaniam ◽  
Shuaijie Wang ◽  
Tanvi Bhatt

Background: Recent studies demonstrate improvements in both postural stability and mobility among aging populations and those with stroke who are exposed to dance-based exergaming (DBExG). However, age-related deficits and aging with cortical pathology may lead to distinct movement adaptation patterns during DBExG, which could impact therapeutic outcomes.Aim: The aim of this study was to examine the movement kinematics (postural stability and mobility) of healthy older adults, older adults with stroke, and young adults for different paces of dance during DBExG. Method: The study included 33 particpants (11 participant from each group of healthy older adults, older adults with chronic stroke, and healthy young adults) who performed the DBExG using slow- (SP), medium- (MP), and fast-paced (FP) songs with movements in the anteroposterior (AP) and mediolateral (ML) directions. Center of mass (CoM) sway area, excursion (Ex), and peaks as well as hip, knee, and ankle joint excursions were computed. Results: Results of the study revealed that CoM sway areas and Exs were greater for healthy young adults than for older adults with stroke for the SP dance (p < 0.05) and that there were significantly more AP CoM peaks for young adults than for healthy older adults and those with stroke for the FP dance (p < 0.05). Young adults also exhibited greater hip and ankle Exs than older adults with stroke (p < 0.05) for all song paces. Similarly, knee and ankle Exs were greater for healthy older adults than for older adults with stroke for all song paces (p < 0.05). Conclusion: The quantitative evaluation and comparison of the movement patterns presented for the three groups could provide a foundation for both assessing and designing therapeutic DBExG protocols for these populations.


Author(s):  
Julia Seinsche ◽  
Wiebren Zijlstra ◽  
Eleftheria Giannouli

In order to design effective interventions to prevent age-related mobility loss, it is important to identify influencing factors. The concept of “motility” by Kaufmann et al. subdivides such factors into three categories: “access”, “skills”, and “appropriation”. The aim of this study was to assemble appropriate quantitative assessment tools for the assessment of these factors in frail older adults and to get first insights into their relative contribution for life-space and physical activity-related mobility. This is an exploratory cross-sectional study conducted with twenty-eight at least prefrail, retired participants aged 61–94. Life-space mobility was assessed using the “University of Alabama at Birmingham Life-space Assessment” (LSA) and physical activity using the “German Physical Activity Questionnaire” (PAQ50+). Factors from the category “appropriation”, followed by factors from the category “skills” showed the strongest associations with the LSA. Factors from the category “access” best explained the variance for PAQ50+. This study’s findings indicate the importance of accounting for and examining comprehensive models of mobility. The proposed assessment tools need to be explored in more depth in longitudinal studies with larger sample sizes in order to yield more conclusive results about the appropriateness of the motility concept for such purposes.


2021 ◽  
Vol 9 ◽  
Author(s):  
Yiwen Zhang ◽  
Xiao-Dan Wang ◽  
Yehua Song ◽  
Ruiqiang Peng ◽  
Ting Tang ◽  
...  

Background: Frequent/urgent urination is an event of multifactorial origin where involuntary leakage of urine occurs. Epidemiological study of this condition is of high importance due to its negative impact on the psychological, physical, and social well-being of the victims.Objective: This cross-sectional study aimed to investigate the prevalence of frequent/urgent urination in older adults in China.Method: In this study, a face-to-face questionnaire survey was conducted between April 2019 and August 2019 among 4,796 older adult populations in the communities of Tianjin jizhou and Xiamen jimei of China. Descriptive analysis, univariate regression, and all statistics were conducted in IBM SPSS v22. The count data were analyzed by chi-square test. P &lt; 0.05 was considered statistically significant.Results: In the total investigated population, the prevalence of frequent or urgent urination was found in 1,164 patients (24.3%) where 31.7% (664/2,097) were male patients and 18.7% (500/2,699) were female patients, having a male-to-female ratio of 1.7:1. The prevalence was higher in the 70- to 84-year-old group (men: 33.3–34.8%, women 19.5–20.8%), whereas it was relatively low in the 65- to 69-year-old group and in older adults over 85 years of age (men 28.8, 30.3%, women 16.7, 18.5%, respectively). In terms of the course of the disease, among the population aged 65 years and above, 17.3% men and 9.9% women had frequent urination/urgency lasting for 1–4 years; 5–9 years in about 4.5% population (7.4% men and 4.2% women); 10–19 years in 4.9% men and 2.3% women; and more than 20 years duration in 1.6% men and 1.9% women. On the severity scale, mild frequent/urgent urination was observed in 24.6% of men and 15.4% women of Chinese older adults. Moderate cases were observed in 6.3% of men and 2.9% of women, whereas severe cases were found in 0.8% men and 0.2% women. Benign prostatic hyperplasia (BPH)/hypertrophy was the main risk factor for frequent/urgent urination in Chinese older adult men (P &lt; 0.001). Obesity, hypertension, diabetes, heart disease, anxiety, depression, constipation, and brain injury were the other risk factors for frequent/urgent urination in Chinese older adult men and women. The results of this survey showed that smoking or drinking habits did not increase the prevalence of frequent/urgent urination in Chinese older adults.Conclusions: According to the results of this survey, the prevalence rate of frequent/urgent urination is high, and the course of the disease is long in Chinese older adults. BPH and depression, anxiety, and age-related chronic diseases increase the risk of frequent/urgent urination in Chinese older adults.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 368-368
Author(s):  
Randi Chen ◽  
Richard Allsopp ◽  
Bradley Willcox ◽  
Philip Davy

Abstract Aging demographics in the US, and other industrialized nations, are resulting in rapidly increasing health care costs from age-related diseases. New therapeutic interventions to extend healthspan in older adults requires understanding connections between basic aging biology and human longevity factors. Using clinical samples from the Kuakini Honolulu Heart Program (HHP) and their Offspring, we are examining potential links between molecular and cellular mechanisms of aging and the longevity associated FOXO3 genotype (carriage of SNP rs2802292 “G” allele). Telomere dynamics in leucocytes (LTL) have shown strong correlation with multiple lifestyle and health factors. We previously demonstrated a significant protective relation between FOXO3 longevity genotype and LTL in a cross-sectional study. Now we are assessing a longitudinal relation, at three time points over 20+ years, in older men. We are also exploring stem cell frequency and differentiation capacity in neurological and peripheral blood samples to assess FOXO3 genotype and human cell dynamics.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 215-215
Author(s):  
Jennifer Piazza ◽  
Jonathan Rush ◽  
Susan Charles

Abstract The current study examined levels of daily NA among people (N=413) who participated in three waves of the National Study of Daily Experiences (~1996; ~2008; ~2017). At each wave, participants reported how often they had experienced six negative emotional experiences every day for eight consecutive days. Cross-sectional analyses at each time-point show age-related decreases in NA. Trajectories over time, however, were moderated by age (Est = .006, SE = .002, p = .001), revealing a curvilinear pattern. Among people who were 25-50 years-old at the first wave, daily NA decreased over time, with decreases more pronounced among the younger adults. For people at least 50 years-old at the start of the study, daily NA increased over time, with the slopes steepest for older adults. Findings indicate that cross-sectional and longitudinal age-related patterns in NA differ when examining data collected from 1996 to 2017.


BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e027768 ◽  
Author(s):  
Tobias Braun ◽  
Christian Thiel ◽  
Carina Ziller ◽  
Julia Rasche ◽  
Carolin Bahns ◽  
...  

ObjectiveTo investigate the prevalence of frailty in older people in outpatient physiotherapy services in an urban region in the western part of Germany.DesignCross-sectional study.SettingOutpatient physiotherapy clinics were recruited in the municipal area of the city of Bochum, Germany, and selected randomly.ParticipantsOlder adults aged 65 years and older seeking outpatient physiotherapy.Primary and secondary outcome measuresPrevalence of frailty was assessed based on the frailty phenotype model of physical frailty and the accumulation of deficit model, expressed as a Frailty Index. Prevalence was calculated for the whole sample and according to age-related, sex-related and diagnosis-related subgroups.ResultsA total of 258 participants (74±6 years, 62% female) from 11 out of 130 (8%) different physiotherapy clinics were included. Participants’ main indication for physiotherapy was an orthopaedic or surgical condition (75%). According to the model of a physical frailty phenotype, 17.8% (95% CI 13.2 to 22.5) participants were frail and 43.4% (95% CI 37.4 to 49.5) were prefrail. The Frailty Index identified 31.0% (95% CI 25.4 to 36.7) of individuals as frail. In both models, prevalence increased with age and was higher in women than in men. Slow gait speed (34%), reduced muscle strength (34%) and exhaustion (28%) were the most prevalent indicators of physical frailty.ConclusionsFrailty is comparatively common in older patients attending physiotherapy care in Germany, with one out of three individuals being frail and every second individual being physically frail or prefrail.Trial registration numberDRKS00009384; Results.


2016 ◽  
Vol 24 (2) ◽  
pp. 311-321 ◽  
Author(s):  
Thais R.S. Paulo ◽  
Sheilla Tribess ◽  
Jeffer Eidi Sasaki ◽  
Joilson Meneguci ◽  
Cristiane A. Martins ◽  
...  

The aim of this study was to examine the association of physical activity with depression and cognition deficit, separately and combined, in Brazilian older adults. We analyzed data from 622 older adults. Physical activity was assessed using the International Physical Activity Questionnaire. Depressive symptoms were assessed using the Geriatric Depression Scale, while cognitive deficit was assessed using the Mini-Mental State Examination. Multinomial logistic regressions were used to assess associations of depression and cognitive deficit with sociodemographic, health, and behavioral variables. Prevalence of physical inactivity (< 150 min of moderate-to-vigorous physical activity/week), depression, and cognitive deficit were 35.7%, 37.4%, and 16.7%. Physical inactivity was associated with depression (OR: 1.83, 95% CI: 1.14–2.94) and with depression and cognitive deficit combined (OR: 4.23, 95% CI: 2.01–8.91). Physically inactive participants were also more likely to present limitations in orientation and language functions. Physical inactivity was associated with depression and also with depression and cognitive deficit combined in older adults.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Roosmarijne M. K. Kox ◽  
H. Roeline W. Pasman ◽  
Martijn Huisman ◽  
Wim Benneker ◽  
Bregje D. Onwuteaka-Philipsen

Abstract Background Literature shows that middle-aged and older adults sometimes experience a wish to die. Reasons for these wishes may be complex and involve multiple factors. One important question is to what extent people with a wish to die have medically classifiable conditions. Aim (1) Estimate the prevalence of a current wish to die among middle-aged and older adults in The Netherlands; (2) explore which factors within domains of vulnerability (physical, cognitive, social and psychological) are associated with a current wish to die; (3) assess how many middle-aged and older adults with a current wish to die do not have a medically classifiable condition and/or an accumulation of age-related health problems. Methods Data of 2015/16 from the Longitudinal Aging Study Amsterdam were used for this cross-sectional study (1563 Dutch middle-aged and older adults aged between 57 and 99 years), obtained through structured medical interviews and self-reported questionnaires. Three experienced physicians assessed whether the participants with a current wish to die could be classified as having a medically classifiable condition and/or an accumulation of age-related health problems. Results N = 62 participants (4.0%) had a current wish to die. Having a current wish to die was associated with multiple characteristics across four domains of vulnerability, among which: self-perceived health, problems with memory, self-perceived quality of life and meaningfulness of life. Fifty-four participants with a current wish to die were assessed with having a medically classifiable condition, of which one was also assessed with having an accumulation of age-related health problems. Six people were assessed to have neither, and for two people it was unclear. Conclusion A small minority of middle-aged and older adults in the Netherlands have a current wish to die. Most of them can be classified with a medical condition and one person with an accumulation of age-related health problems. Furthermore, the findings show that having a current wish to die is multi-faceted. There is still a need for more knowledge, such as insight in to what extent suffering stemming from the medical classifiable disease contributes to the development of the wish to die.


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