scholarly journals Pulmonary fibrosis following infection with SARS-CoV-2 in a pregnant woman: case report

2020 ◽  
Author(s):  
Somaye Moeindarbary ◽  
Salmeh Dadgar ◽  
Parvaneh Layegh ◽  
Zahra Shahriari ◽  
Faezeh Fayyaz ◽  
...  

Abstract Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the third coronavirus that make a global concern in 21th century. Pregnant women are particularly at higher risk of developing severe viral pneumonia, possibly because of a partial immune suppression during their pregnancy. Under such critical and rapidly evolving circumstances, these poor findings might be helpful for the treatment of infected pregnant women with 2019-nCoV.Case presentation: In this study, we have reported a pregnant woman at 25 gestational weeks with COVID-19 who has developed severe complications, including hypoxemia, acute respiratory distress syndrome (ARDS), pulmonary fibrosis, and bilateral pleural effusion. In the end, she died one month after admission to the hospital.Conclusion: Pregnant population are especially more at risk of viral pneumonia caused by coronaviruses, further research on the prevention and treatment of new coronavirus is necessary.

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Somayeh Moeindarbary ◽  
Salmeh Dadgar ◽  
Parvaneh Layegh ◽  
Zahra Shahriari ◽  
Faezeh Fayyaz ◽  
...  

Abstract Introduction Severe acute respiratory syndrome coronavirus 2 is the third member of the coronavirus family to cause global concern in the twenty-first century. Pregnant women are particularly at higher risk of developing severe viral pneumonia, possibly because of a partial immune suppression during their pregnancy. Under such critical and rapidly evolving circumstances, these poor findings might be helpful for the treatment of infected pregnant women with the 2019 novel coronavirus. Case presentation In this study, we report the case of a 33-year-old Asian pregnant woman at 25 gestational weeks with coronavirus disease 2019 who developed severe complications, including hypoxemia, acute respiratory distress syndrome, pulmonary infiltration, and bilateral pleural effusion. She died 1 month after admission to the hospital. Conclusion Pregnant populations are especially at higher risk of viral pneumonia development caused by severe acute respiratory syndrome coronavirus 2. Further research on the prevention and treatment of the new coronavirus is necessary.


2021 ◽  
pp. 38-55
Author(s):  
A. V. Vlasenko ◽  
E. A. Evdokimov ◽  
E. P. Rodionov

The paper summarizes data on modern approaches to the diagnosis, prevention and treatment of severe acute parenchymal respiratory failure of various origins, including ARDS due to bacterial viral pneumonia. The work is based on the data of modern well-organized studies, analysis of international clinical guidelines with a high degree of evidence, as well as the results of our own long-term experimental studies and clinical observations of the treatment of patients with ARDS of various origins, including viral pneumonia of 2009, 2016, 2020. Scientifically grounded algorithms for prevention, differential diagnosis and personalized therapy of severe acute respiratory failure using innovative medical technologies and a wide range of respiratory and adjuvant treatment methods have been formulated. The authors tried to adapt as much as possible the existing current recommendations for the daily clinical practice of anesthesiologists and resuscitators.


2020 ◽  
Vol 9 (7-8) ◽  
pp. 698-699
Author(s):  
M. Ginzburg

Dr. Davis reported three fatal cases of vomiting during pregnancy. In the first of them, the pregnant woman suffered from gastric disorders before pregnancy; her vomiting was incessant and very exhausted her. She died at 2 months of pregnancy. Before dying, she developed a petechia-shaped spotty rash. In the second case, severe nausea and vomiting occurred at 3 weeks of pregnancy with severe pain and belching, locally: prolapsus and anteflexio uteri. The usual treatment. At 14 weeks, the anteflexed uterus was infringed at the bottom behind the pubis; the correction did not reduce vomiting. The expansion of the neck was accompanied by a slight improvement. It was decided to empty the uterus, which was done without difficulty and with minor bleeding. The patient, however, died soon after. An autopsy showed that the tissue of the uterine cervix was abnormally hard (fibrous); the uterus, ovaries, and tubes were normal; the blood was thin, fatty degeneration of the heart. In the third case, the patient, in addition to nausea and vomiting, suffered from severe pain in the epigastric region and vomiting had a coffee color. Everything possible was done, but nothing helped: the patient died.


2018 ◽  
Vol 5 (6) ◽  
pp. 643
Author(s):  
Erly Krisnanik ◽  
Kraugusteeliana Kraugusteeliana ◽  
Vini Indriasari

<p class="Abstrak">Sistem pakar merupakan salah satu aplikasi yang dapat digunakan oleh manusia sebagai media untuk mendapatkan data dan informasi secara tepat berdasarkan pengetahuan dan pengalaman seorang pakar kandungan dan pakar gizi. Proses pengetahuan data pakar tadi disimpan dalam basis pengetahuan yang disertai aturan berdasarkan konklusi yang telah ditetapkan oleh peneliti untuk dijadikan sebagai referensi. Hasil dari pelacakan data kemudian di informasikan kepada pengguna sistem dalam hal ini wanita hamil (wamil) yang ingin mengetahui menu sehat dan nutrisi tambahan. Untuk mengetahui menu sehat wamil peneliti menggunakan metode cooper sebagai acuan perhitungan yang dimasukkan kedalam mesin inferensi. Adapun hal yang dijadikan sebagai perhitungan gizi menu sehat bagi wamil berdasarkan usia wamil, tri semester, usia kandungan, perhitungan gizi, berat ideal wamil berdasarkan tinggi badan, hitung kalori minimal, dan hitung kalori berdasarkan aktifitas wamil. Sedangkan metode yang digunakan untuk aplikasi pakar menggunakan pendekatan forward chaining dengan DFS untuk mekanisme pelacakan datanya. Luaran yang dihasilkan dari penelitian ini adalah berupa desain model sistem pakar kebutuhan menu dan nutrisi bagi wanita hamil dengan pendekatan metode cooper yang bertujuan memudahkan wamil mendapatkan informasi dengan cepat dan tepat.</p><p class="Abstrak"> </p><p><strong><em>Abstract</em></strong></p><p><em></em><br /><em>The expert system is one of the applications used by humans as a media to acquire precise data and information based on obstetricians and nutritionist’s knowledge and experience. The expert’s instruction is stored in a knowledge base accompanied by rules based on a fixed conclusion for references. The result of the data trace is informed to a system user. In this case pregnant woman who wanted to know the healthy menu and additional nutrition. Many pregnant women rarely consult obstetricians and nutritionist due to their routine and the high cost of it. This caused pregnant women cannot control their nutrition growth as well as and their baby’s nutrition. Based on that case, we design an expert system to know suitable healthy menu for a pregnant woman using cooper’s method. The menu of pregnant woman is calculated using the following parameters: 1) The age of pregnant women; 2) The third month of pregnancy; 3) Nutrition calculation; 4) Ideal weights of pregnant women based on their heights; 5) Minimum calorie count of pregnant women; and 6) Calorie count of pregnant women based on their activities. While the method used for the expert system application is based on forwarding chaining approach with DFS as it is data tracking system mechanism. The output resulted from this research is a model design of the expert system to find a suitable healthy menu and additional nutrition for pregnant women with cooper’s method as an approach, intended to help pregnant women to acquire quick and accurate information.</em></p><p> </p>


2021 ◽  
pp. 38-54
Author(s):  
A. V. Vlasenko ◽  
E. A. Evdokimov ◽  
E. Р. Rodionov

The paper summarizes data on modern approaches to the diagnosis, prevention and treatment of severe acute parenchymal respiratory failure of various origins, including ARDS due to bacterial viral pneumonia. The work is based on the data of modern well-organized studies, analysis of international clinical guidelines with a high degree of evidence, as well as the results of our own long-term experimental studies and clinical observations of the treatment of patients with ARDS of various origins, including viral pneumonia of 2009, 2016, 2020. Scientifically grounded algorithms for prevention, differential diagnosis and personalized therapy of severe acute respiratory failure using innovative medical technologies and a wide range of respiratory and adjuvant treatment methods have been formulated. The authors tried to adapt as much as possible the existing current recommendations for the daily clinical practice of anesthesiologists and resuscitators.


2020 ◽  
pp. 65-67
Author(s):  
K. Arun Vishnu ◽  
Athul.C. Angaj ◽  
Trinath Dash

PULMONARY FIBROSIS IS A FREQUENT COMPLICATION IN PATIENTS WITH VIRAL PNEUMONIA-INDUCED ACUTE RESPIRATORY DISTRESS SYNDROME. HOWEVER, CT SCANS HAVE SHOWN THAT THE SIGNS OF PULMONARY FIBROSIS AFTER VIRAL PNEUMONIA CAN PARTIALLY REGRESS OVER TIME. SO NOW A DAYS, AS A PART OF COVID TREATMENT, FOR PREVENTING FIBROSIS, WE ARE GIVING ANTI FIBROTICS AND STEROIDS. BUT WE DON’T KNOW THE ACTUAL SEQUALE OF LESIONS IN LUNG DUE TO COVID. HERE WE WOULD LIKE TO DISCUSS ABOUT OUR CASE OF SEVERE COVID-19 INFECTION WHO WAS MANAGED WITH ANTI-FIBROTICS, NIV, ANTI-VIRALS, STEROIDS AND PRONE VENTILATION. THIS PARTICULAR PATIENT HAD CT SEVERITY SCORE OF 21/25 WITH B/L GGOs, FIBROTIC BANDS AND CONSOLIDATORY CHANGES. A 1 MONTH FOLLOW-UP CT SCAN SHOWED A REDUCTION IN CT SEVERITY SCORE (15/25) AND GROSS RESOLUTION IN CONSOLIDATORY CHANGES AND GGOs. THE CLINICAL CONDITION SHOWED A SIGNIFICANT IMPROVEMENT.


2020 ◽  
Vol 17 (3) ◽  
pp. 61-78
Author(s):  
A. V. Vlasenko ◽  
E. A. Evdokimov ◽  
E. P. Rodionov

The review summarizes data on contemporary approaches to diagnosis, prevention and treatment of severe acute parenchymal respiratory failure of various origins including in acute respiratory distress syndrome (ARDS) caused by bacterial and viral pneumonia. It is based on the data of modern properly organized studies, an analysis of international clinical guidelines with a high degree of evidence, as well as the results of many years of own experimental research and clinical observations of treatment of patients with ARDS of various origin, including those with viral pneumonia in 2009–2016–2020. The article states scientifically-based procedures for prevention, differential diagnosis and personalized treatment of severe acute respiratory failure with the use of innovative medical technologies and a wide range of respiratory treatments. The authors did their best to adapt specific proposals for everyday clinical practice.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Chunjuan Shen ◽  
Ling Ai ◽  
Kai Li ◽  
Yunfei Cao ◽  
Hanbing Wu ◽  
...  

Abstract Background Metastatic choriocarcinoma in the third trimester of pregnancy is extremely rare. Case presentation A 25-year-old Chinese woman (gravida 3, para 0) who was 28 weeks pregnant was admitted for sudden convulsion, aconuresis, and unconsciousness. The decision was made to perform an emergency cesarean delivery and craniotomy, hematoma clearance, and decompression. Pathological examination confirmed choriocarcinoma with brain metastasis. The patient underwent chemotherapy with the etoposide, cisplatin (EP) and etoposide, methotrexate and dactinomycin alternating with cyclophosphamide and vincristine (EMACO) regimens. A satisfactory result was achieved. Conclusions When encountering intracranial mass or bilateral pulmonary nodules in a pregnant woman, especially one in the third trimester, metastatic choriocarcinoma should be considered.


2021 ◽  
pp. 25-37
Author(s):  
A. V. Vlasenko ◽  
E. A. Evdokimov ◽  
E. P. Rodionov

The paper summarizes data on modern approaches to the diagnosis, prevention and treatment of severe acute parenchymal respiratory failure of various origins, including ARDS due to bacterial viral pneumonia. The work is based on the data of modern well-organized studies, analysis of international clinical guidelines with a high degree of evidence, as well as the results of our own long-term experimental studies and clinical observations of the treatment of patients with ARDS of various origins, including viral pneumonia of 2009, 2016, 2020. Scientifically grounded algorithms for prevention, differential diagnosis and personalized therapy of severe acute respiratory failure using innovative medical technologies and a wide range of respiratory and adjuvant treatment methods have been formulated. The authors tried to adapt as much as possible the existing current recommendations for the daily clinical practice of anesthesiologists and resuscitators.


2018 ◽  
Vol 3 (1) ◽  
pp. 1
Author(s):  
Murwati Murwati ◽  
Emy Suryani ◽  
Intan Kurniawati

Anxiety is an unclear worried and widespread related to uncertain and helpless feelings. Anxiety before birth was questioning and wondering whether she could giving birth normally, how to push, whether something could happen during childbirth, and pain during labor. Anxiety in the third trimester of pregnant women can have an impact inhibiting the labor. Antenatal class is one form of counseling as an effort to overcome anxiety to face labour for third trimester pregnant mother. The aims of this study is to determine the relation of class participation of pregnant mother with the anxiety to face labour among third trimester pregnant woman. This was an observational analytic study with cross sectional design. The sample were the third trimester pregnant woman in Jogonalan II Klaten public health center area totalling 36 people using purposive sampling. The study instrument used was questionnaire of pregnant women's class participation and an anxiety rating scale (HARS) of the Hamilton Anxiety Rating Scale. Data analysis was performed using Spearman test. The results of this study shown that most of respondent age was 20-35 years which is 91.7%, high school education accounted for 52.8%, unemployed accounted for 69.4% and multigravida accounted for 63.9%. Antenatal class participation rate was 52.8% and mother who did not experience anxiety accouted for 63,9%. The result of statistical test obtained ρ = 0,001. There was an association between antenatal class participation with anxiety level in facing childbirth in third trimester pregnant women. Keywords: Antenatal class participation, anxiety of third trimester pregnant mother in facing childbirth 


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