scholarly journals Frailty and sarcopenia in elderly non-dialysis patients with chronic kidney disease stage 3-5: a cross sectional study

2020 ◽  
Author(s):  
Jing Chang ◽  
Yan-Fei Wang ◽  
Wen-Wen Hou ◽  
Yan-Chun Li ◽  
Zhuo-Ran Qi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Cross Sectional Study ◽  
Disease Stage ◽  
Sectional Study ◽  
Dialysis Patients ◽  
Cross Sectional ◽  
Independent Risk Factors

Abstract Background With the aging of the population, chronic kidney disease (CKD) and sarcopenia are the common diseases among the elderly. Non-dialysis patients with CKD account for a relatively high proportion, and the analysis of their general clinical characteristics has been more familiar. However, the study of sarcopenia in non-dialysis with CKD is not enough. Methods This is a cross sectional study. Non-dialysis patients with CKD stage 3–5 were continuously selected. Patients were divided into 3 groups based on the Fried scale, Non-frail group, Pre-frail group and Frail group. At the same time, muscle mass of the hospitalized patients was measured by dual-energy X-ray absorptiometry (DXA), and according to the test results, they were divided into sarcopenia and non-sarcopenia group. Baseline data and the measurement of the sarcopenia of the two groups were analyzed. Results A total of 102 elderly patients with chronic kidney disease stage 3–5 were continuously enrolled. There were 21 patients (20.6%) categorized as sarcopenia, 81 patients (79.4%) categorized as non-sarcopenia according to the measurement results of DXA. Frailty was assessed by the criteria of frailty phenotype, there were 13 patients of sarcopenia in the frail group, 6 patients of sarcopenia in the pre-frail group, and 2 patients of sarcopenia in the non-frail group, accounting for 31.7%, 20.0%, 6.5%, respectively. Moreover, the analysis of the related risk factors of sarcopenia showed that body mass index (BMI)༜23 kg/m2(OR = 3.82, 95%CI 1.33–10.97, P = 0.013), MNA-SF ≤ 11(OR = 3.97, 95%CI 1.08–14.58, P = 0.038) were the independent risk factors for sarcopenia in non-dialysis patients with chronic kidney disease stage 3–5. Conclusions The prevalence of sarcopenia in elderly non-dialysis patients with chronic kidney disease stage 3–5 was high, and sarcopenia was common in the frail patients. BMI༜23 kg/m2 and MNA-SF ≤ 11were the independent risk factors for sarcopenia in non-dialysis patients with chronic kidney disease stage 3–5.

scholarly journals Secreted Klotho and FGF23 in chronic kidney disease Stage 1 to 5: a sequence suggested from a cross-sectional study

2012 ◽  
Vol 28 (2) ◽  
pp. 352-359 ◽  
Author(s):  
Ivana Pavik ◽  
Philippe Jaeger ◽  
Lena Ebner ◽  
Carsten A. Wagner ◽  
Katja Petzold ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Cross Sectional Study ◽  
Disease Stage ◽  
Sectional Study ◽  
Cross Sectional ◽  
Stage 1

scholarly journals Public Knowledge of Chronic Kidney Disease in a Resource-Limited Setting: A Cross-Sectional Study.

2021 ◽  
Author(s):  
Abdella Birhan YABEYU ◽  
Kaleab Haile ◽  
Yared Belay ◽  
Henok Tegegn
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Knowledge Score ◽  
Cross Sectional Study ◽  
Public Knowledge ◽  
General Knowledge ◽  
Sectional Study ◽  
Cross Sectional ◽  
One Way Anova

Aim: Awareness of chronic kidney disease (CKD) includes general knowledge of CKD and its risk factors. The current study aimed at assessing the public knowledge of CKD by using a validated tool. Methods: A community-based cross-sectional study was conducted. The target population of this study was lay public, and health professionals were excluded from the study. Proportional numbers of study participants were included from each sub-city based on their total population size. The data was analyzed using SPSS version 21. Frequencies, table’s percentage, mean and standard deviation were used to describe participants’ responses: Independent T-test and one way ANOVA statics was used to identify factors associated with public knowledge of CKD. Results: A total of 350 individuals were approached, 301 of whom completed and returned the questionnaire, giving a response rate of 86%. In this study, the mean (S.D.) knowledge score of participants was 11.12 (±4.21), with a minimum of 0 and a maximum of 22. Concerning the distribution of the CKD knowledge score, half of the respondents score 11 and less. One way ANOVA revealed that educational level had a significant effect on knowledge of CKD. Respondents who had an educational background of degree had relatively higher knowledge scores than the other category participants (P-value= 0.015). An independent t-test was also performed but failed to reveal any association between socio-demographic characteristics and knowledge score. Conclusions: The general knowledge level of the Ethiopian population about CKD and its risk factors is low. Currently, non-communicable disease such as diabetes and hypertension becomes public health concern and are one of the significant risk factors for CKD. As the study indicated, even these groups of populations were not adequately informed regarding their increased risk of developing CKD. Keywords: chronic kidney disease, public knowledge, Ethiopia

scholarly journals Distribution of Pruritus and Its Association With Serum Parathormone Level in Chronic Kidney Disease (Stage-5) Patients On Maintenance Hemodialysis

2020 ◽  
Vol 28 (1) ◽  
pp. 54-59
Author(s):  
Rafiqul Hasan ◽  
Md Nizamuddin Chowdhury ◽  
Md Nazrul Islam ◽  
Parvez Iftekher Ahmed ◽  
ASM Tanim Anwar ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Normal Serum ◽  
Disease Stage ◽  
Maintenance Hemodialysis ◽  
Cross Sectional ◽  
Maintenance Haemodialysis

Background: Pruritus is a common manifestation in patients on hemodialysis. The aim of this study is to determine the distribution of pruritus and evaluate the association between pruritus and serum parathormone levels in chronic kidney disease patients on maintenance haemodialysis. Methods:This analytic, descriptive, cross-sectional study was performed over 191 patients of maintenance haemodialysis in 2014. Information related to the patients including age, gender, residence, pruritus was extracted from questionnaires. Serum levels of intact parathormone were measured & data were analyzed. Results: 68% of the patients had pruritus. The Mean ± SD of serum parathormone was 53.25±7.96 pg/ml in patients with pruritus and 81.91±9.34 pg/ml in patients without pruritus. Our study showed that most patients with pruritus had normal serum parathormone levels and no significant association was found between pruritus and serum parathormone levels. Conclusion: serum parathormone level may not play a role in uraemic pruritus in these patients. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 54-59

scholarly journals Risk factors for chronic kidney disease: a hospital based cross sectional study from Visakhapatnam

2018 ◽  
Vol 5 (9) ◽  
pp. 3909
Author(s):  
Sindhura Moparthi ◽  
Madhavi Seepana ◽  
Devi Madhavi Bhimarasetty
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Data Entry ◽  
Public Health Problem ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Dialysis Unit

Background: Chronic kidney disease (CKD) is being increasingly recognised as a leading public health problem. In India, given its population >1 billion, the rising incidence of CKD is likely to pose major problems for both healthcare and the economy in future years. Diabetes and hypertension are strong predictors for development and progression of chronic kidney disease. The objective of the study was to assess risk factors for chronic kidney disease among patients undergoing dialysis in King George Hospital (KGH), Visakhapatnam.Methods: This is an observational descriptive cross sectional study done in dialysis unit in KGH. A total of 100 patients were selected out of 141 registered CKD patients by simple random sampling technique. Study is done in the month of October- November 2015. A pretested semi structured schedule was administered. Informed written consent was taken from the patients. MS excel 2007 was used for data entry. Data was analysed by SPSS trial version 20. Categorical data was analysed by Chi square test.Results: Among 100 study subjects 72 were females and 28 were males. 91% of the CKD patients were Hypertensive, among whom 73.6% were males and 26.4% were females. This difference was not found to be statistically significant (p=0.446). 22% of the CKD patients were Diabetic, among whom 81.8% were males and 18.2% were females.Conclusions: Better understanding of the role of risk factors in CKD is needed. Large community based cross sectional studies are needed to study in detail about CKD risk factors. 

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