scholarly journals Urine di-(2-Ethylhexyl) Phthalate Metabolites Are Independently Related To Body Fluid Status in Adults: Results From a U.S. Nationally Representative Survey

2021 ◽  
Author(s):  
Wei-Jie Wang ◽  
Chia-Sung Wang ◽  
Chi-Kang Wang ◽  
An-Ming Yang ◽  
Chien-Yu Lin
Keyword(s):  
Body Fat ◽  
Body Fluid ◽  
Adult Population ◽  
Linear Regression Analysis ◽  
Extracellular Fluid ◽  
Sampling Strategy ◽  
Fluid Status ◽  
The Relationship ◽  
Ethylhexyl Phthalate ◽  
Dehp Exposure

Abstract Background Di-(2-ethylhexyl) phthalate (DEHP) has been utilized in many daily used products for decades. Previous studies have reported DEHP exposure could induce renin-angiotensin-aldosterone system activation and increase epithelial sodium channel (ENaC) activity, which contributes to extracellular fluid (ECF) volume expansion. However, there is also no previous study to evaluate the association between DEHP exposure and body fluid status. Methods We selected 1,678 subjects (aged ≧ 18 years) from a National Health and Nutrition Examination Survey (NHANES) in 2003–2004 to determine the relationship among urine DEHP metabolites and body composition (body measures, bioelectrical impedance analysis (BIA)). Results After weighted for sampling strategy, we reported higher levels of DEHP metabolites was correlated with increases in body measures (body weight, body mass index (BMI), waist), parameters of BIA (estimated fat mass, percent body fat, ECF, and ECF /intracellular fluid (ICF) ratio) in multiple linear regression analysis. The relationship between DEHP metabolites with ECF/ICF ratio were more evident in subjects with younger age (20–39 year-old), women, non-Hispanic white ethnic, and subjects who were not active smokers. Conclusions Besides positively correlated with body measures and body fat, we found urine DEHP metabolites are positively correlated with ECF, ECF/ICF ratio in the US general adult population. It is necessary to do further research to clarify this causal relationship.

scholarly journals Characteristics of Intracellular and Extracellular Fluid Ratio for the Varying Body Impedances in Fixed Total Body Fluid

2017 ◽  
Author(s):  
JungHun Choi
Keyword(s):  
Human Body ◽  
High Frequency ◽  
Body Fluid ◽  
Extracellular Fluid ◽  
Bioelectrical Impedance ◽  
The Body ◽  
Horizontal Axis ◽  
Fluid Status ◽  
Total Body ◽  
Frequency Current

A bioelectrical impedance analysis is a proven method to measure body composition in clinical situations. It uses the relation between the body fluid and the impedances in a variety of frequencies. A body model can be simplified as a parallel combination of a capacitor and two resistors which represent a cell membrane, Intracellular Fluid (ICF), and Extracellular Fluid (ECF). Low frequency current passes through ECF and high frequency current also passes through ICF in a body. A Cole-Cole plot is a graphical interpretation of the path of impedances and each axis represents resistance and reactance with variable frequencies. A high value of resistance in a horizontal axis is a resistance value of ECF and a low value of resistance at a high frequency presents ICF. Interpolation technique is needed to find out the exact cross-point between impedance values and the horizontal axis. The two estimated impedance values are used to derive Total Body Water (TBW), ICF, ECF, Fat Free Mass (FFM), and Fat Mass (FM) from various published equations [1]. Minimizing the possible error of fluid volume assessment and accurate prediction of fluid status in a human body is essential for appropriate therapy. Different techniques of fluid status assessment in a human body can be applicable, such as physical examination, orthostatic vital signs, blood volume measurement, acoustic cardiograph, chest radiography, and thoracic ultrasonography [2]. In this study, a bioelectrical impedance spectroscopy device and simple body models were used to collect data such as TBW, ICF, ECF, FM, and FFM. The ratio between ICF and ECF was investigated for the same values of TBW, FM, and FFM by varying impedance values.

Relationship of Heart Rate and Oxygen Uptake Kinetics during Deep Water Running in the Adult Population—Ages 50 to 70 Years

1998 ◽  
Vol 6 (3) ◽  
pp. 248-255 ◽  
Author(s):  
Stanley P. Brown ◽  
Joel C. Jordan ◽  
Linda F. Chitwood ◽  
Kim R. Beason ◽  
John G. Alvarez ◽  
...  
Keyword(s):  
Older Adults ◽  
Heart Rate ◽  
Oxygen Uptake ◽  
Deep Water ◽  
Adult Population ◽  
Linear Regression Analysis ◽  
Regression Equations ◽  
Physiological Variables ◽  
The Relationship ◽  
Deep Water Running

This study was performed to investigate the relationship between heart rate (HR) as a percentage of peak HR and oxygen uptake (V̇O2) as a percentage of peak V̇O2 in older adults while performing deep water running (DWR). Twenty-three (14 male and 9 female) apparently healthy older adults, age 50 to 70 years, volunteered. Deep water running to V̇O2peak was performed in 3-min stages at leg speeds controlled by a metronome beginning at 60 strides per minute and increasing 12 strides per minute each additional stage. Oxygen uptake and HR were continuously monitored by open-circuit spirometry and radiotelemetry, respectively. Simple linear regression analysis was used to establish the relationship between the physiological variables. The relationship between %V̇O2peak and %HRpeak was statistically significant, with the male (%V̇O2peak = 1.5301 [%HRpeak] − 54.4932 [r = .96, SEE = 6.0%]) and female (%V̇O2peak = 1.5904 [%HRpeak] - 62.3935 [r = .91, SEE = 6.9%]) regression equations being significantly different (p < .05). The regression equations of older adults and those for college-aged males (%VO2peak = 1.4634 [%HRpeak] − 49.619) and females (%V̇O2peak = 1.6649 [%HRpeak] − 67.862) were not significantly different.

scholarly journals Anthropometric Indicators of Adiposity Related to Body Weight and Body Shape as Cardiometabolic Risk Predictors in British Young Adults: Superiority of Waist-to-Height Ratio

2018 ◽  
Vol 2018 ◽  
pp. 1-15 ◽  
Author(s):  
Farzad Amirabdollahian ◽  
Fahimeh Haghighatdoost
Keyword(s):  
Young Adults ◽  
Body Weight ◽  
Body Fat ◽  
Body Shape ◽  
Dietary Habits ◽  
Adult Population ◽  
Linear Regression Analysis ◽  
Height Ratio ◽  
Body Adiposity ◽  
Waist To Height Ratio

Frequently reported poor dietary habits of young adults increase their risk of metabolic syndrome (MetS). Excess adiposity is the most established predictor of MetS, and numerous anthropometric measures have been proposed as proxy indicators of adiposity. We aimed to assess prevalence of MetS in young adult population and to make comparison between weight- and shape-oriented measures of adiposity to identify the best index in association with measured body fat and as a risk predictor for MetS. Healthy males and females aged 18–25 years from the Northwest of England were recruited using convenience sampling (n=550). As part of the assessment of the overall health of young adults, the biochemical variables and adiposity measures BMI, waist circumference (WC), waist-to-height ratio (WHtR), waist-to-hip ratio (WHR), new BMI, Body Adiposity Index (BAI), Clinica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE), and A Body Shape Index (ABSI) were assessed. Linear regression analysis was used to investigate the association between the proxy indices of adiposity and measured percentage body fat. The odds ratio with 95% confidence interval was used to investigate the relationship between cardiometabolic (CM) risk factors and proxy measures of adiposity. The discriminatory power of these measures for diagnosis of MetS was investigated using area under the receiver operating characteristic curve. Body weight-related indicators of adiposity, particularly CUN-BAE, had stronger association with measured body fat compared with body shape-related indices. In relation with MetS, body shape-related indices, particularly elevated WC and WHtR, had stronger associations with CM risk compared with body weight-related measures. Amongst all indices, the best predictor for CM risk was WHtR, while ABSI had the weakest correlation with body fat, MetS, and CM risk. Indices directly associated with WC and specifically WHtR had greater diagnostic power in detection of CM risk in young adults.

scholarly journals Effects of Refractive Errors and Age on Binocular Function in Normal Adult Population

2020 ◽  
Author(s):  
Xiaodong Zhou ◽  
Man She ◽  
Tao Li ◽  
Qianqian Hu ◽  
Jie Zhu
Keyword(s):  
Adult Population ◽  
Linear Regression Analysis ◽  
Age Groups ◽  
Normal Adult ◽  
Comfort Zone ◽  
Mean Values ◽  
Binocular Function ◽  
The Mean ◽  
The Relationship ◽  
Vision Function

Abstract Purpose: To investigate the relationship between binocular function with gender, ages, and spherical equivalent (SE) .Methods: This observational study enrolled 243 healthy, non-strabismic adults, including 94 men and 149 women aged from 20 to 59 years. The subjects were divided into three groups according to SE: myopic group, emmetropic group and hyperopic group. The subjects were also divided into four groups according to age: 20-29 years group, 30-39 years group, 40-49 years group, and 50-59 years group. The binocular vision function was measured with a synoptophore, including subjective angle (SA), divergence, convergence and fusional vergence range (FVR). Results: The mean values of SA, divergence, convergence and range of fusion for the whole sample group were 3.33±0.16°, 9.72±0.26°, 19.34±0.54°, and 29.06±0.62°, respectively. The mean values of SA and divergence in myopic group were significantly larger than the emmetropic group (both p<0.05). SE, SA, divergence and FVR were significantly different among age groups (all p<0.05). Besides, linear regression analysis showed SE was correlated with SA and divergence (p=0.007, p=0.003). Age was correlated with SE, SA, divergence and FVR (p<0.001, p<0.001, p=0.005, p=0.002, respectively). In addition, the proportion of SA being in comfort zone (defined as the value of SA located in the middle 1/3 area of FVR) in age groups were statistically different. (χ2=8.283, p=0.041)Conclusion: Both SA and motor fusion are associated with age and SE in normal adult population.

scholarly journals Epidemiologic Data of Vitamin D Deficiency and Its Implication in Cardio-Cerebrovascular Risk in a Southern Italian Population

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Rocco Capuano ◽  
Federica Marchese ◽  
Raffaella Sica ◽  
Eduardo Capuano ◽  
Marzia Manilia ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Southern Italy ◽  
Close Association ◽  
Adult Population ◽  
Linear Regression Analysis ◽  
Hdl Cholesterol ◽  
Blood Cholesterol ◽  
Italian Population ◽  
The Relationship

Background. Vitamin D (25(OH)D) deficiency is a prevalent condition worldwide. However, the highest prevalence rates of 25(OH)D deficiency have been attributed to regions with higher latitude. A close association between 25(OH)D and cardio-cerebrovascular (CCV) risk factors and major health problems has been identified. Aim. To establish the prevalence of 25(OH)D deficiency and to investigate the relationship between 25(OH)D levels and CCV risk factors (blood cholesterol, triglycerides, glucose concentrations, body mass index, and systolic and diastolic blood pressure) in a cohort representative of Southern Italy. Methods. The prevalence of 25(OH)D levels was evaluated in 1200 subjects aged 25–74 years (600 males and 600 females), enrolled in the “VIP” (from Italian for Irno Valley Prevention) Project, whereas multiple linear regression analysis was used to determine the relationship between 25(OH)D levels and CCV risk factors. Results. Only 13.3% of females and 11.1% of males showed adequate serum concentrations of 25(OH)D (≥30 ng/ml), while 59.3% of females and 55.1% of males showed 25(OH)D deficient levels (<20 ng/ml). We observed an independent association between 25(OH)D concentrations and metabolic syndrome score, LDL cholesterol, HDL cholesterol, and corrected QT (cQT). Conclusions. We report a high prevalence of 25(OH)D deficiency across the largest Italian adult population studied so far and, in particular, the first across Southern Italy; furthermore, we provide data on the association between 25(OH)D deficiency and higher CCV risk factors.

The Influences of Palindromes in mRNA on Protein Folding Rates

2020 ◽  
Vol 27 (4) ◽  
pp. 303-312 ◽  
Author(s):  
Ruifang Li ◽  
Hong Li ◽  
Sarula Yang ◽  
Xue Feng
Keyword(s):  
Protein Folding ◽  
Regression Analysis ◽  
Linear Regression ◽  
Linear Regression Analysis ◽  
Folding Rate ◽  
Folding Rates ◽  
Negative Linear Correlation ◽  
Protein Folding Rate ◽  
The Relationship ◽  
Structure Environment

Background: It is currently believed that protein folding rates are influenced by protein structure, environment and temperature, amino acid sequence and so on. We have been working for long to determine whether and in what ways mRNA affects the protein folding rate. A large number of palindromes aroused our attention in our previous research. Whether these palindromes do have important influences on protein folding rates and what’s the mechanism? Very few related studies are focused on these problems. Objective: In this article, our motivation is to find out if palindromes have important influences on protein folding rates and what’s the mechanism. Method: In this article, the parameters of the palindromes were defined and calculated, the linear regression analysis between the values of each parameter and the experimental protein folding rates were done. Furthermore, to compare the results of different kinds of proteins, proteins were classified into the two-state proteins and the multi-state proteins. For the two kinds of proteins, the above linear regression analysis were performed respectively. Results : Protein folding rates were negatively correlated to the palindrome frequencies for all proteins. An extremely significant negative linear correlation appeared in the relationship between palindrome densities and protein folding rates. And the repeatedly used bases by different palindromes simultaneously have an important effect on the relationship between palindrome density and protein folding rate. Conclusion: The palindromes have important influences on protein folding rates, and the repeatedly used bases in different palindromes simultaneously play a key role in influencing the protein folding rates.

scholarly journals Is Hip Muscle Strength Associated with Dynamic Knee Valgus in a Healthy Adult Population? A Systematic Review

2021 ◽  
Vol 18 (14) ◽  
pp. 7669
Author(s):  
Ali Mohammed Alzahrani ◽  
Msaad Alzhrani ◽  
Saeed Nasser Alshahrani ◽  
Wael Alghamdi ◽  
Mazen Alqahtani ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Adult Population ◽  
Knee Valgus ◽  
Journal Articles ◽  
Hip Muscle ◽  
Hip Abductor ◽  
Hip Muscles ◽  
Analysis System ◽  
The Relationship ◽  
External Rotator

This study aimed to systematically review research investigating the association between hip muscle strength and dynamic knee valgus (DKV). Four databases (MEDLINE, PubMed, CINAHL, and SPORTDiscus) were searched for journal articles published from inception to October 2020. Seven studies investigating the association between hip muscle strength and DKV using a two-dimensional motion analysis system in healthy adults were included. The relationship between hip abductor muscle strength and DKV was negatively correlated in two studies, positively correlated in two studies, and not correlated in three studies. The DKV was associated with reduced hip extensor muscle strength in two studies and reduced hip external rotator muscle strength in two studies, while no correlation was found in three and five studies for each muscle group, respectively. The relationship between hip muscle strength, including abductors, extensors, and external rotators and DKV is conflicting. Considering the current literature limitations and variable methodological approaches used among studies, the clinical relevance of such findings should be interpreted cautiously. Therefore, future studies are recommended to measure the eccentric strength of hip muscles, resembling muscular movement during landing. Furthermore, high-demand and sufficiently challenging functional tasks revealing lower limb kinematic differences, such as cutting and jumping tasks, are recommended for measuring the DKV.

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