scholarly journals Effects of Refractive Errors and Age on Binocular Function in Normal Adult Population

2020 ◽  
Author(s):  
Xiaodong Zhou ◽  
Man She ◽  
Tao Li ◽  
Qianqian Hu ◽  
Jie Zhu
Keyword(s):  
Adult Population ◽  
Linear Regression Analysis ◽  
Age Groups ◽  
Normal Adult ◽  
Comfort Zone ◽  
Mean Values ◽  
Binocular Function ◽  
The Mean ◽  
The Relationship ◽  
Vision Function

Abstract Purpose: To investigate the relationship between binocular function with gender, ages, and spherical equivalent (SE) .Methods: This observational study enrolled 243 healthy, non-strabismic adults, including 94 men and 149 women aged from 20 to 59 years. The subjects were divided into three groups according to SE: myopic group, emmetropic group and hyperopic group. The subjects were also divided into four groups according to age: 20-29 years group, 30-39 years group, 40-49 years group, and 50-59 years group. The binocular vision function was measured with a synoptophore, including subjective angle (SA), divergence, convergence and fusional vergence range (FVR). Results: The mean values of SA, divergence, convergence and range of fusion for the whole sample group were 3.33±0.16°, 9.72±0.26°, 19.34±0.54°, and 29.06±0.62°, respectively. The mean values of SA and divergence in myopic group were significantly larger than the emmetropic group (both p<0.05). SE, SA, divergence and FVR were significantly different among age groups (all p<0.05). Besides, linear regression analysis showed SE was correlated with SA and divergence (p=0.007, p=0.003). Age was correlated with SE, SA, divergence and FVR (p<0.001, p<0.001, p=0.005, p=0.002, respectively). In addition, the proportion of SA being in comfort zone (defined as the value of SA located in the middle 1/3 area of FVR) in age groups were statistically different. (χ2=8.283, p=0.041)Conclusion: Both SA and motor fusion are associated with age and SE in normal adult population.

scholarly journals Relationship between age, refractive errors and motor fusion in a normal Chinese adult population: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Man She ◽  
Tao Li ◽  
Qianqian Hu ◽  
Jie Zhu ◽  
Xiaodong Zhou
Keyword(s):  
Adult Population ◽  
Linear Regression Analysis ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Comfort Zone ◽  
Cross Sectional ◽  
Mean Values ◽  
Chinese Adult ◽  
The Mean

Abstract Background To investigate the relationships between motor fusion and sex, age and spherical equivalent (SE). Methods This observational study enrolled 243 healthy, nonstrabismic adults, including 94 men and 149 women aged 20 to 59 years. The subjects were divided into three groups according to SE: myopic, emmetropic and hyperopic groups. The subjects were also divided into four groups according to age: 20–29, 30–39, 40–49 and 50–59 years groups. Motor fusion was measured with a synoptophore, including subjective angle (SA), divergence, convergence and fusional vergence range (FVR). Results The mean values of divergence, convergence and FVR for the whole sample group were 9.72 ± 0.26°, 19.34 ± 0.54°, and 29.06 ± 0.62°, respectively. A higher value of divergence was found in the myopic group than in the emmetropic group (p < 0.05). SE and divergence were significantly different among age groups (all p < 0.05). In addition, linear regression analysis showed that SE was correlated with divergence (p = 0.003). Age was correlated with SE, divergence and FVR (p < 0.001, p = 0.005, p = 0.002, respectively). In addition, the proportion of SA being in the comfort zone (defined as the value of SA satisfying Percival’s criterion) in the age groups was significantly different (χ2 = 8.283, p = 0.041). Conclusions Motor fusion is associated with age and SE in the normal Chinese adult population.

How landscape and climate affect the spatial variability of the Italian rainfall extremes? Some initial clues based on I2-RED

2021 ◽  
Author(s):  
Paola Mazzoglio ◽  
Ilaria Butera ◽  
Pierluigi Claps
Keyword(s):  
Spatial Variability ◽  
Linear Regression Analysis ◽  
Alpine Region ◽  
Annual Rainfall ◽  
Mean Values ◽  
Rainfall Extremes ◽  
Geomorphological Parameters ◽  
The Mean ◽  
The Relationship ◽  
Italian Territory

&lt;p&gt;The intensity and the spatial distribution of precipitation depths are known to be highly dependent on relief and geomorphological parameters. Complex environments like mountainous regions are prone to intense and frequent precipitation events, especially if located near the coastline. Although the link between the mean annual rainfall and geomorphological parameters has received substantial attention, few literature studies investigate the relationship between the sub-daily maximum annual rainfall depth and geographical or morphological landscape features.&lt;br&gt;In this study, the mean of the rainfall extremes in Italy, recently revised in the so-called I&lt;sup&gt;2&lt;/sup&gt;-RED dataset, are investigated in their spatial variability in comparison with some landscape and also some broad climatic characteristics. The database includes all sub-daily rainfall extremes recorded in Italy from 1916 until 2019 and this analysis considers their mean values (from 1 to 24 hours) in stations with at least 10 years of records, involving more than 3700 stations.&lt;br&gt;The geo-morpho-climatic factors considered range from latitude, longitude and minimum distance from the coastline on the geographic side, to elevation, slope, openness and obstruction morphological indices, and also include an often-neglected robust climatological information, as the local mean annual rainfall.&lt;br&gt;Obtained results highlight that the relationship between the annual maximum rainfall depths and the hydro-geomorphological parameters is not univocal over the entire Italian territory and over different time intervals. Considering the whole of Italy, the highest correlation is reached between the mean values of the 24-hours records and the mean annual precipitation (correlation coefficient greater than 0.75). This predominance remains also in sub-areas of the Italian territory (i.e., the Alpine region, the Apennines or the coastal areas) but correlation decreases as the time interval decreases, except for the Alpine region (0.73 for the 1-hour maximum). The other geomorphological parameters seem to act in conjunction, making it difficult to evaluate, with a simple linear regression analysis, their impact. As an example, the absolute value of the correlation coefficient between the elevation and the 1-hour extremes is greater than 0.35 for the Italian and the Alpine regions, while for the 24-hours interval it is greater than 0.35 over the coastal areas.&lt;br&gt;To further investigate the spatial variability of the relationship between rainfall and elevation, a spatial linear regression analysis has been undertaken. Local linear relationships have been fitted in circles centered on any of the 0.5-km size pixels in Italy, with 1 to 30 km radius and at least 5 stations included. Results indicate the need of more comprehensive terrain analysis to better understand the causes of local increasing or decreasing relations, poorly described in the available literature.&lt;/p&gt;

scholarly journals Near Points of Convergence and Accommodation in a Population of University Students in IranNear Points of Convergence and Accommodation in a Population of University Students in Iran

2019 ◽  
Author(s):  
Hassan Hashemi ◽  
Mojgan Pakbin ◽  
Babak Ali ◽  
Abbasali Yekta ◽  
Hadi Ostadimoghaddam ◽  
...  
Keyword(s):  
University Students ◽  
Adult Population ◽  
Age Groups ◽  
Multiple Linear Regression Model ◽  
Total Sample ◽  
Cluster Sampling ◽  
Young Student ◽  
Mean Values ◽  
Snellen Chart ◽  
The Mean

Purpose: To determine the distribution of the near point of convergence (NPC) and near point of accommodation (NPA) in a young student population in Iran. Methods: The subjects were selected using a cluster sampling method. All students underwent optometry tests, including visual acuity measurement, refraction, and cover test, as well as ophthalmic examinations. The NPC and NPA were measured using an accommodative target (near Snellen chart). Results: Of 1,595 students, the data of 1,357 were analyzed. The mean NPC and NPA in the total sample were 7.25 cm (95% confidence interval [CI], 7.02 to 7.48) and 9.99 cm (95% CI, 9.69 to 10.29), respectively. Older age was associated with an increase in the NPC, which increased from 6.98 cm in 18–20 years olds to 9.51 cm in those over 30 years. The NPA was significantly associated with age and refractive errors in the multiple linear regression model, increasing from 9.92 cm in 18–20 years olds to 11.44 cm in those over 30 years (P = 0.003). Hyperopic eyes had lower NPA than myopic and emmetropic eyes (P = 0.001). In younger age groups, the mean accommodation amplitude was lower than the mean Hofstetter value. Moreover, with age, especially after 30 years, the mean values surpassed those determined using the Hofstetter formula. Conclusion: The NPC values in this study were lower than those previously reported for identical age groups. The Hofstetter formula is not always an accurate predictor of the accommodation amplitude in the Iranian adult population.

scholarly journals The relationship between demographic features, anthropometric parameters, sleep duration, and physical activity with ECG parameters in Fasa Persian cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Alireza Mirahmadizadeh ◽  
Mojtaba Farjam ◽  
Mehdi Sharafi ◽  
Hossein Fatemian ◽  
Maryam Kazemi ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cohort Study ◽  
Linear Regression ◽  
Sleep Duration ◽  
Linear Regression Analysis ◽  
Previous History ◽  
Multivariate Linear Regression Analysis ◽  
Mean Values ◽  
The Mean ◽  
The Relationship

Abstract Backgrounds Cardiovascular Diseases (CVDs) are the first leading cause of death worldwide. The present study aimed to investigate the relationship between demographics, anthropometrics, sleep duration, physical activity, and ECG parameters in the Fasa Persian cohort study. Methods In this cross-sectional study, the basic information of 10,000 participants aged 35–70 years in the Fasa cohort study was used. The data used in this study included demographic data, main Electrocardiogram (ECG) parameters, anthropometric data, sleep duration, and physical activity. Data analysis was performed using t-test, chi-square, and linear regression model. Results Based on multivariate linear regression analysis results, increased age was significantly associated with all study parameters. Nevertheless, gender and body mass index showed no significant relationship with SV3 and PR. Wrist circumference, hip circumference and waist circumference significantly increased the mean values of the ECG parameters. However, sleep duration was not significantly associated with the ECG parameters. In addition, hypertension was major comorbidity, which was shown to increase the mean values of the ECG parameters. Conclusion Several factors affected the ECG parameters. Thus, to interpret ECGs, in addition to age and gender, anthropometric indices, physical activity, and previous history of comorbidities, such as hypertension and ischemic heart disease, should be taken into consideration.

scholarly journals AB0101 THE IMPACT OF TIME SPAN TO ACHIEVE BOOLEAN REMISSION FOR MAINTAINING DISEASE ACTIVITY AFTER ACQUISITION IN RHEUMATOID ARTHRITIS PATIENT

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1079.1-1079
Author(s):  
I. Yoshii
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Disease Duration ◽  
Remission Rate ◽  
Mean Value ◽  
Time Span ◽  
Mean Values ◽  
The Mean ◽  
The Relationship

Background:Boolean remission criteria is one most popular and stringent criteria in treating patient with rheumatoid arthritis (RA), because it may guarantees a stable clinical course after attaining remission.Objectives:Impact of time span from initiation to achieving Boolean remission on maintaining disease activity, daily activities, and quality of life after attaining Boolean remission was investigated from daily clinical practice data.Methods:685 patients with RA since August 2010 under the T2T strategy were treated. They were monitored for their TJC, SJC, PGA, EGA, CRP, and disease activity indices such as CDAI, SDAI, DAS28, and Boolean criteria at every visit. HAQ-DI score, pain score using visual analog scale (PS-VAS), and EQ-5D were also monitored, and the quality of life score (QOLS) calculated from EQ-5D was determined at every visit from the time of diagnosis (baseline).Of 685 patients, 465 patients had achieved Boolean remission >1 times, and were consecutively followed up for >3 years. These patients were enrolled in the study. Time span from the first visit to first Boolean remission was calculated. The relationship between the time span and each of background parameters, and the relationship between the time span and each of the mean values of the SDAI score, HAQ score, PS-VAS, SHS, and QOLS at the first Boolean remission and thereafter was evaluated statistically.Patients were subsequently divided into the G ≤ 6 and G > 6 groups based on the achievement of first Boolean remission within two groups: time span G ≤ 6 months and G > 6 months. The two groups were compared with regard to the SDAI score, HAQ score, PS-VAS, SHS, and QOLS at first visit and at the time of first Boolean remission, and the mean values of these parameters after remission were evaluated statistically. Moreover, changes of these parameters and the mean Boolean remission rate after the first remission, and SDAI remission rate at the first Boolean remission to thereafter were compared between the two groups statistically.Results:Out of 465 patients, females comprised 343 (73.7%), and the mean age was 67.8 years (range, from 21–95 years). The mean disease duration at first visit was 6.1 years (range, from 1 months–45 years). The mean follow up length was 88.1 months (range: 36–122 months; median: 85 months) and mean time span from the first visit to the first Boolean remission was 8.1 months. The mean SDAI score, HAQ score, PS-VAS, and the QOLS at first visit were 13.3, 0.467, 33.2, and 0.834, respectively. Among the study parameters, PS-VAS and QOLS were significantly correlated with the time span. For parameters at the first Boolean remission, HAQ-DI score, PS-VAS, and QOLS demonstrated significant correlation with the time span, whereas SDAI, HAQ-DI score, PS-VAS, SHS, and QOLS after the Boolean remission demonstrated significant correlation with the time span.The comparison between the G ≤ 6 and the G > 6 groups revealed that the disease duration, HAQ score, and PS-VAS at baseline in the G > 6 were significantly higher than that in the G ≤ 6 group, and QOLS in the G ≤ 6 group was significantly higher than that in the G > 6 group at baseline. Similarly, the HAQ score and PS-VAS at the first Boolean remission in the G > 6 group were significantly higher than that in the G ≤ 6 group, whereas QOLS in the G ≤ 6 group demonstrated no significant difference compared with that in the G > 6 group.The mean value of the SDAI score after the first Boolean remission in the G > 6 group was significantly higher than that in the G ≤ 6 group. Similarly, the SDAI score, HAQ score, and PS-VAS after the first Boolean remission in the G > 6 group were also significantly higher than those in the G ≤ 6 group, and the mean value of the QOLS in the G ≤ 6 group were significantly higher than that in the G > 6 group. The Boolean remission rate and SDAI remission rate after the first Boolean remission were significantly higher in the G ≤ 6 group than those in the G > 6 group.Conclusion:Attaining Boolean remission ≤ 6 months for RA has significant benefit for more stable disease control, that leads good maintenance of ADL.Disclosure of Interests:None declared

scholarly journals Determinants of serum 25-hydroxyvitamin D in Hong Kong

2015 ◽  
Vol 114 (1) ◽  
pp. 144-151 ◽  
Author(s):  
Cuiling Xu ◽  
Ranawaka A. P. M. Perera ◽  
Yap-Hang Chan ◽  
Vicky J. Fang ◽  
Sophia Ng ◽  
...  
Keyword(s):  
Vitamin D ◽  
Hong Kong ◽  
Southern China ◽  
Age Groups ◽  
Dietary Vitamin ◽  
Skeletal Health ◽  
Mean Values ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
The Mean

Vitamin D plays an important role in skeletal health throughout life. Some studies have hypothesised that vitamin D may reduce the risk of other diseases. Our study aimed to estimate age-specific and sex-specific serum 25-hydroxyvitamin D (25(OH)D) status and to identify the determinants of serum 25(OH)D status in Hong Kong, a subtropical city in southern China. In 2009–2010, households in Hong Kong were followed up to identify acute respiratory illnesses, and sera from 2694 subjects were collected in three to four different study phases to permit measurement of 25(OH)D levels at different times of the year. A questionnaire survey on diet and lifestyle was conducted among children, with simultaneous serum collection in April and May 2010. The mean of serum 25(OH)D levels in age groups ranged from 39 to 63 nmol/l throughout the year with the mean values in all age groups in spring below 50 nmol/l. Children aged 6–17 years, and girls and women had significantly lower serum 25(OH)D levels than adults, and boys and men, respectively (allP< 0·001). We estimated that serum 25(OH)D levels in Hong Kong followed a lagged pattern relative to climatic season by 5 weeks with lowest observed levels in early spring (March). For children aged 6–17 years, reporting a suntan, having at least 1 servings of fish/week and having at least 1 serving of eggs/week were independently associated with higher serum 25(OH)D levels. Adequate sunlight exposure and increased intake of dietary vitamin D could improve vitamin D status, especially for children and females in the winter and spring.

​Impact of Extreme Hot Environmental Temperature Period on Marker Enzymes of Carbohydrate Metabolism in Non-descript Sheep from Arid Tracts of Rajasthan

2021 ◽  
Author(s):  
Anandita Srivastava ◽  
Nalini Kataria
Keyword(s):  
Carbohydrate Metabolism ◽  
Environmental Temperature ◽  
Age Groups ◽  
Extreme Temperature ◽  
Mean Value ◽  
Marker Enzymes ◽  
Mean Values ◽  
The Mean ◽  
The Impact ◽  
Enzymes Of Carbohydrate Metabolism

Background: The present investigation was envisaged to find out the impact of extreme hot environmental temperature period (ETP) on marker enzymes of carbohydrate metabolism in male and female non-descript sheep of various age groups i.e. 4 to 13 months from arid tracts of Rajasthan. Glucose-6-phosphate dehydrogenase (G-6-PDH) and malate dehydrogenase (MDH) marker enzymes of carbohydrate metabolism were considered for study. Methods: During the period October 2016-June 2017 blood samples were collected to harvest sera for spectrophotometric method from 240 healthy animals selected from private slaughter house during moderate and extreme hot environmental temperature periods (ETPs). The mean values of markers attained during moderate ETP were reckoned as the control. It was 10.00 ± 0.10 UL-1 and 42.00±1.00 respectively. Conclusion: The mean value of MDH was significantly (p≤0.05) higher while G-6-PDH significantly (p≤0.05) lowers during extreme hot temperature in comparison to moderate period. Therefore, it could be concluded that variations in enzyme markers were associated with changes in environmental temperatures. Probably ETP were able to produce a profound effect on carbohydrate metabolism in sheep. Therfore it can be suggested that during the period of extreme temperature balanced ration must be provided to the animal along with proper management to decrease the severity of temperature impact.

scholarly journals OR30-01 Real-World Minimed™ 670G System Use and Glycemic Outcomes of Pediatric and Adult Individuals Living with Type 1 Diabetes (T1D) in the United States

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Robert Alan Vigersky ◽  
Michael Stone ◽  
Pratik Agrawal ◽  
Alex Zhong ◽  
Kevin Velado ◽  
...  
Keyword(s):  
Glycemic Control ◽  
Real World ◽  
Adult Population ◽  
Age Groups ◽  
The United States ◽  
System Use ◽  
System Data ◽  
The Mean ◽  
The Impact ◽  
The U.S

Abstract Introduction: The MiniMed™ 670G system was FDA-approved in 2016 for adults and adolescents ≥14yrs, and in 2018 for children ages 7-13yrs with T1D. Since then, use of the system has grown to over 180,000 people in the U.S. The glycemic control benefits of real-world MiniMed™ 670G system Auto Mode use in the U.S. were assessed. Methods: System data (aggregated five-minute instances of sensor glucose [SG]) uploaded from March 2017 to July 2019 by individuals (N=118,737) with T1D and ≥7yrs of age who enabled Auto Mode were analyzed to determine the mean % of overall time spent &lt;54mg/dL/&lt;70mg/dL (TBR); between 70-180mg/dL (TIR); and &gt;180mg/dL/&gt;250mg/dL (TAR). The impact of Auto Mode was further assessed in a sub-group of individuals (N=51,254) with, at least, 7 days of SG data for both Auto Mode turned ON and turned OFF. The % of TIR, TBR and TAR, and the associated glucose management indicator (GMI) were evaluated for the overall OFF (2,524,570 days) and ON (6,308,806 days) periods, and across different age groups. Results: System data TIR was 71.3%; TBR was 0.4% and 1.9%, respectively; and TAR was 26.8% and 6.2%, respectively. User-wise data of Auto Mode OFF versus ON showed a mean of 70.3% of the time spent in Auto Mode, that TIR increased from 60.9% to 69.9%; and that both TBR and TAR decreased. For those 7-13yrs (N=1,417), TIR increased from 48.7% to 61.5%; TBR increased from 0.5% to 0.6% and from 2.0% to 2.2%, respectively; and TAR decreased from 49.3% to 36.3% and from 20.5% to 13.0%, respectively. For those 14-21yrs (N=4,194), TIR increased from 51.0% to 61.5%; TBR decreased from 0.7% to 0.6% and from 2.3% to 2.0%, respectively; and TAR decreased from 46.7% to 36.5% and from 18.5% to 12.5%, respectively. For those ≥22yrs (N=45,643), TIR increased from 62.2% to 70.9%; TBR decreased from 0.7% to 0.5% and from 2.6% to 1.9%, respectively; and TAR decreased from 35.2% to 27.3% and from 9.9% to 6.3%, respectively. The mean GMI decreased by 0.23% (overall), 0.48% (7-13yrs), 0.35% (14-21yrs), and 0.22% (≥22yrs), respectively, with Auto Mode ON versus OFF. Discussion: In over 6 million days of real-world MiniMed™ 670G system Auto Mode use in the U.S., TIR of a large pediatric and adult population with T1D improved by 9% compared to when Auto Mode was OFF, which was comparable to or exceeded the TIR observed in the smaller pivotal trials. These results further support outcomes of the pivotal trials and increased glycemic control with system use.

Blood and plasma volume in adult males

1962 ◽  
Vol 17 (2) ◽  
pp. 195-198 ◽  
Author(s):  
Marvin J. Yiengst ◽  
Nathan W. Shock
Keyword(s):  
Plasma Volume ◽  
Age Groups ◽  
Dilution Method ◽  
Total Blood Volume ◽  
Adult Males ◽  
Age Changes ◽  
Total Blood ◽  
Mean Values ◽  
The Mean ◽  
Blood Volumes

Total blood volumes were estimated in 94 normal ambulatory males, aged 19–95 years, by the T-1824 dye dilution method. There were no significant age changes when results were expressed in terms of either body weight or surface area. The mean values for individual age groups between 40'49 and 80'95 years varied between 46.7 ± 1.5 and 51.5 ± 1.5 ml/kg body wt. for plasma volume and between 75.1 ± 2.0 and 82.3 ± 2.0 ml/kg body wt. for total blood volume. Submitted on October 16, 1961

scholarly journals Preservation of phase-type distributions under Poisson shock models

1992 ◽  
Vol 24 (01) ◽  
pp. 223-225 ◽  
Author(s):  
M. Manoharan ◽  
Harshinder Singh ◽  
Neeraj Misra
Keyword(s):  
Continuous Phase ◽  
Finite Mixture ◽  
Life Distribution ◽  
Mean Values ◽  
Shock Models ◽  
Phase Type ◽  
Phase Type Distributions ◽  
Discrete Phase ◽  
The Mean ◽  
The Relationship

In this paper, we consider the life distribution H(t) of a device subject to shocks governed by a finite mixture of homogeneous Poisson processes. It will be shown that if (pk ), the probabilities that the device fails on the kth shock, has a discrete phase-type (DPH) distribution, then H(t) is continuous phase-type (CPH). The relationship between the mean values of (pk ) and H(t) is established.

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