scholarly journals Case Report: Gastric Cancer Combined With Bilateral Ovarian Metastasis In Pregnancy

2021 ◽  
Author(s):  
Zhenhua Zhang ◽  
Gang Lv ◽  
Mei Liu ◽  
Miaohui Lin ◽  
Meilin Xie ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Case Report ◽  
Early Diagnosis ◽  
Malignant Tumors ◽  
Ovarian Metastasis ◽  
Ovarian Mass ◽  
Health Checkup ◽  
Case Presentation ◽  
Treatment Plans ◽  
In Pregnancy

Abstract Background: The early manifestations of gastric cancer during pregnancy are non-specific. Ovarian mass and ascites are the main manifestations of late ovarian metastasis. Case presentation: A case of late gastric cancer with bilateral ovarian metastasis in pregnancy was reported in our study. Cesarean section and full staging of ovarian malignant tumors were performed at 28+5 weeks of pregnancy, and the prognosis was poor. We performed Cesarean delivery and extracted a vital male newborn of 35 cm, 1020 g, Ap score 3. The newborn is alive and grows normally. Three months later the mother died. The key to improving the prognosis is early diagnosis, and the pre-pregnancy health checkup must be emphasized. Conclusions: During pregnancy, ultrasound, gastroscopy, MRI and other related examinations should be performed to confirm the diagnosis, and individualized treatment plans should be formulated to maximize the protection of the mother and child's interests.

scholarly journals Primary Hyperparathyroidism in Pregnancy: A Two-Case Report and Literature Review

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
A. D. Herrera-Martínez ◽  
R. Bahamondes-Opazo ◽  
R. Palomares-Ortega ◽  
C. Muñoz-Jiménez ◽  
M. A. Gálvez-Moreno ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Early Diagnosis ◽  
Literature Review ◽  
Primary Hyperparathyroidism ◽  
Serum Levels ◽  
Second Trimester ◽  
Uncommon Disease ◽  
Fetal Complications ◽  
In Pregnancy

Primary hyperparathyroidism (PHPT) in pregnant women is an uncommon disease. It could be easily misdiagnosed because of physiologic changes during pregnancy; in some cases, patients could remain asymptomatic maintaining elevated calcium serum levels, and this situation represents a threat to the health of both mother and fetus. We present two cases of PHPT during pregnancy and their evolution after surgical treatment in the second trimester; there were no observed complications during pregnancy or delivery in our patients. Early diagnosis and medical/surgical treatment in PHPT are necessary for avoiding maternal and fetal complications which could not be predicted based on duration or severity of hypercalcemia. An appropriate management of PHPT during pregnancy is necessary for preserving the health of both the woman and the fetus.

Circulating serum exosomal miR-92a-3p as a novel biomarker for early diagnosis of gastric cancer

2021 ◽  
Vol 17 (8) ◽  
pp. 907-919
Author(s):  
Xu Lu ◽  
Jianxin Lu ◽  
Siqi Wang ◽  
Yu Zhang ◽  
Ye Ding ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Diagnosis ◽  
Malignant Tumors ◽  
Area Under The Curve ◽  
Tumor Biomarker ◽  
Diagnostic Efficiency ◽  
Node Metastasis ◽  
Tumor Node Metastasis Stage ◽  
Combined Detection ◽  
Serum Exosomes

Gastric cancer (GC) is one of the common malignant tumors with high mortality. The abundance of miRNAs in serum exosomes has proved to have a high application value as a new noninvasive diagnostic method. The purpose of this study was to investigate whether serum exosomal miR-92a-3p could be used as a new biomarker for early diagnosis of GC and evaluate its clinical application value by detecting the expression of serum exosomal miR-92a-3p in 131 patients with primary GC and 122 healthy controls by real-time quantitative (qRT)-PCR. The results showed that the expression level of serum exosomal miR-92a-3p in GC patients was significantly lower than that in normal controls (p < 0.0001). In addition, the level was closely correlated with lymph node metastasis and tumor node metastasis stage of GC patients. The area under the curve for serum exosomal miR-92a-3p was 0.829, significantly higher than for other indicators. Furthermore, combined detection of serum exosomal miR-92a-3p, CEA and CA19-9 was more sensitive than any of the three alone or any pair. These results showed that serum exosomal miR-92a-3p could be used as a novel new tumor biomarker to improve diagnostic efficiency in GC.

Acute leukemia in pregnancy with ovarian metastasis: a case report and review of the literature

2003 ◽  
Vol 13 (6) ◽  
pp. 904-908 ◽  
Author(s):  
M. C. Terek ◽  
E. Ozkinay ◽  
O. Zekioglu ◽  
Y. Erhan ◽  
S. Cagirgan ◽  
...  
Keyword(s):  
Case Report ◽  
Acute Leukemia ◽  
Ovarian Metastasis ◽  
Review Of The Literature ◽  
In Pregnancy

scholarly journals Advancing Mandibular Swelling: A Diagnostic Dilemma

2013 ◽  
Vol 14 (4) ◽  
pp. 754-758
Author(s):  
KF Basavaraj ◽  
AU Madihalli ◽  
Abdul Mujeeb ◽  
Samir Mansuri ◽  
Mohammed Abid Hussain
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Early Diagnosis ◽  
Treatment Planning ◽  
Malignant Tumors ◽  
Accurate Diagnosis ◽  
Illustrative Case ◽  
Diagnostic Dilemma ◽  
Radiological Features ◽  
The Face

ABSTRACT Asymmetrical swelling of the mandible in adolescence may pose a significant diagnostic dilemma. The differential diagnosis ranges from traumatic, infectious, and metabolic processes to benign and malignant tumors. Also may present with similar clinical and radiological features, making an accurate diagnosis quite difficult. This is an illustrative case involving a 30-year-old female who initially presented with complaint of pain and swelling in the lower left side of the face for 2 months. Multiple investigations and several biopsies were required to arrive at a diagnosis. This paper deals with a case report of a fibrosarcoma involving the mandible highlighting the importance of early diagnosis and treatment planning. How to cite this article Basavaraj KF, Madihalli AU, Mujeeb A, Mansuri S, Hussain MA. Advancing Mandibular Swelling: A Diagnostic Dilemma. J Contemp Dent Pract 2013;14(4):754-758.

scholarly journals Hibernoma of Thigh: A Case Report of 39-Year-Old Male

2021 ◽  
Vol 11 (10) ◽  
Author(s):  
Nasser Sulaiman Alqadhib ◽  
Osama Saleh Alshaya
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Malignant Tumors ◽  
Present Report ◽  
Brown Fat ◽  
Medial Aspect ◽  
Case Presentation ◽  
Tissue Tumor ◽  
Atypical Lipoma

Introduction: Hibernoma is an uncommon benign lipomatous tumor that originates from residual brown fat. It commonly affects adult patients aged between 30 and 40 with a slight predominance in male more than female and usually seen in the thigh, shoulder, back, chest, axilla, and neck. The present report aimed to highlight on a viable differential diagnosis of thigh mass including liposarcoma and atypical lipoma. Case Presentation: This is the case report with detailed history, examination of 39-year-old male patient with hibernoma over medial aspect of thigh. Marginal surgical resection was carried and sent to histopathology to confirm the diagnosis of hibernoma. Conclusion: Hibernoma is a rare benign lipomatous soft tissue tumor with no known risk for malignant transformation or metastasis. Based on imaging examination, it can mimic malignant tumors such as, liposarcoma, in which we believe that biopsy is required in order to reach the diagnosis in most of the cases. Keywords: Soft tissue tumor, hibernoma, brown fat, liposarcoma.

scholarly journals Management of Pheochromocytoma in Pregnancy: Case Report and Review of the Literature

2013 ◽  
Vol 5 (1) ◽  
pp. 45-47
Author(s):  
A. Reklou ◽  
A. Kamparoudis ◽  
A. Mamopoulos ◽  
A. Lazaridis ◽  
P. Rakitzi ◽  
...  
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Early Pregnancy ◽  
Mortality Rates ◽  
Review Of The Literature ◽  
Fetal Complications ◽  
In Pregnancy

Pheochromocytoma during pregnancy is rare and lethal to the mother and fetus. Its diagnosis is often missed during pregnancy and is usually made during labour or immediately postpartum with increased mortality rates for both the mother and fetus. Early diagnosis and timely, appropriate management reduce possible maternal and fetal complications. A case of pheochromocytoma recognized at early pregnancy is described

scholarly journals Case Report: Gastric Carcinoma Diagnosed at the Second Trimester of Pregnancy

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Tayfur Cift ◽  
Begüm Aydogan ◽  
Murat Akbaş ◽  
Burcu Aydın ◽  
Fuat Demirkiran ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Differential Diagnosis ◽  
Case Report ◽  
Rare Case ◽  
Normal Pregnancy ◽  
Metastatic Gastric Cancer ◽  
Second Trimester ◽  
Cancer In Pregnancy ◽  
Very High ◽  
In Pregnancy

We report a rare case of gastric cancer in pregnancy. A 26-year-old woman presented at the 20th week of pregnancy complaining of nausea and vomiting. Although the patient considered the condition to be related with pregnancy and underestimated its importance, her complaints persisted over the following weeks and she was hospitalized for investigation. The diagnostic workup revealed a metastatic gastric cancer. Gastric cancer is very rare in pregnancy, and therefore it may be left out of differential diagnosis by physicians. Diagnosis may be further delayed because of overlapping symptoms occurring during normal pregnancy (nausea, vomiting, and fatigue). All these factors may contribute to a very high mortality of this malignancy during pregnancy.

scholarly journals COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report

2021 ◽  
Author(s):  
Nadine El Kassis ◽  
Wael Abdallah ◽  
Rim Abou Chakra ◽  
Wissam Arab ◽  
Serge Sassine ◽  
...  
Keyword(s):  
Case Report ◽  
Pregnant Woman ◽  
Cesarean Section ◽  
Protective Effect ◽  
Passive Immunization ◽  
Prior History ◽  
Case Presentation ◽  
Maternal Vaccination ◽  
History Of ◽  
In Pregnancy

Aim: Evaluating the newborn passive immunization after maternal vaccination against SARS-COV-2. Case presentation: We present the case of a pregnant woman, with no prior history of COVID-19 infection, who got her second dose of mRNA vaccine against SARS-COV-2, 3 days before the start of her spontaneous labor. She was delivered by cesarean section after dynamical dystocia. Placental cord blood was retrieved immediately and sent to evaluate the titers of COVID-19 antibodies. Vaccine-generated antibodies were present in the umbilical cord with IgG spike >100 AU/ml. Conclusion: By reviewing the literature, vaccination seems to give hope about the potential protective effect of the maternal vaccination on her baby. Thus, pregnant women deserve a priority in the COVID-19 vaccination program.

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