scholarly journals Factors Associated With Low Relapse Rates of Schizophrenia In Southern Thailand: A University Hospital-Based Study

2021 ◽  
Author(s):  
Jarurin Pitanupong ◽  
Pran Ratanaapiromyakij ◽  
Teerapat Teetharatkul
Keyword(s):  
Life Events ◽  
Relapse Prevention ◽  
Medical Records ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Psychotic Episode ◽  
Psychiatric Unit ◽  
Factors Associated ◽  
Adherence To Medication ◽  
Relapse Rates

Abstract Background: Schizophrenia is a chronic disease that has residual symptoms and relapse. Relapse prevention research will provide useful knowledge for the employment of an effective caring process. This study aims to explore factors associated with relapse rates in hospital where there are comparatively low relapse rates for schizophrenia. Method: Medical records of patients who had their first schizophrenia diagnosis, in the Songklanagarind hospital’s inpatient psychiatric unit, were retrospectively reviewed for the period from January 2007 to December 2019. This yielded data outlining demographic information, profiles of schizophrenia and treatment. Descriptive statistical analysis was utilized to process all data; and factors associated to relapse were investigated using bivariate and multivariate analyses. Results: Reviewed medical records identified a sample size of 156 schizophrenias. The majority were male (50.6%), Buddhist (85.9%), unmarried (80.1%), unemployed (50.6%) and living with their families (90.4%). Their mean age was 39.2 years. Relapse was defined as readmission to a psychiatric unit within 5 years after their first psychotic episode. From the 156 patients, 53.8% featured relapse whereas 46.2% were in remission. Cumulatively, the first to the fifth-year relapse rate was 22.4%, 35.3%, 44.9%, 50.0%, and 53.8% respectively. Multivariate analysis indicated that patients having stressful life events, non-adherence to medication, prescription changes and lack of insight were all factors with a statistically significant association to relapse rates.Conclusions: Stressful life events, adverse events, medical non-adherence, change prescription, and lack of insight were related to relapse. Emphasizing multimodality of treatment could be key to successful relapse prevention for schizophrenia.

scholarly journals Factors Associated with Psychiatric Comorbidity in Depression Patients in Primary Health Care in Chile

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Alfredo Cancino ◽  
Marcelo Leiva-Bianchi ◽  
Carlos Serrano ◽  
Soledad Ballesteros-Teuber ◽  
Cristian Cáceres ◽  
...  
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Life Events ◽  
Psychiatric Comorbidity ◽  
Stressful Life Events ◽  
Clinical Severity ◽  
Stressful Life ◽  
Psychiatric Comorbidities ◽  
Factors Associated ◽  
Primary Health

Objective. To identify the clinical and psychosocial factors associated with psychiatric comorbidity in patients consulting for depression in Primary Health Care (PHC) in Chile. Methods. 394 patients with a diagnosis of major depression being treated in a Chilean PHC were evaluated using a sociodemographic and clinical interview, the mini-international neuropsychiatric interview (MINI), a childhood trauma events (CTEs) screening, the intimate partner violence (IPV) scale, the Life Experiences Survey (LES), and the Hamilton Depression Rating Scale (HDRS). Results. Positive correlations were established between higher number of psychiatric comorbidities and severity of depressive symptoms (r = 0.358), frequency of CTEs (r = 0.228), frequency of IPV events (r = 0.218), frequency of recent stressful life events (r = 0.188), number of previous depressive episodes (r = 0.340), and duration of these (r = 0.120). Inverse correlations were determined with age at the time of the first consultation (r = -0.168), age of onset of depression (r = -0.320), and number of medical comorbidities (r = -0.140). Of all associated factors, early age of the first depressive episode, CTEs antecedents, and recent stressful life events explain 13.6% of total variability in psychiatric comorbidities. Conclusions. A higher prevalence of psychiatric comorbidity among subjects seeking help for depression in Chilean PHCs is associated with early onset of depression, clinical severity, chronicity, and interpersonal adversity experienced since childhood.

scholarly journals Stressful Life Events In First Episode Psychosis

2021 ◽  
Vol 10 (1) ◽  
pp. 38-42
Author(s):  
B.D. Karki ◽  
D. Joshi ◽  
A.P. Adhikari
Keyword(s):  
Life Events ◽  
Perceived Stress ◽  
Stressful Life Events ◽  
First Episode Psychosis ◽  
Stressful Life ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Psychotic Episode ◽  
Episode Psychosis

Introduction: First episode psychosis refers to the first time someone experiences psychotic symptoms or a psychotic episode. There are evidences related to the role of major life events and childhood trauma in the development of first episode psychosis. There are few studies regarding the environmental exposure to stressful life events and how these events might influence the onset of a psychotic disorder, and role of perceived stress. This study aimed to identify the relationship between stressful life events and first episode psychosis in Nepalese context. Material And Method: It was a hospital based cross-sectional, descriptive study. A total of 50 cases of first episode psychosis were included and the diagnosis was made according to ICD 10- Diagnostic Criteria for Research and verified by two consultant psychiatrists. Semi Structured Performa was designed to collect the information about the socio demographic data and perceived stress was assessed with Presumptive Stressful Life Events Scale (PSLES). Results: There were 62% female and 38% male patients with first episode psychosis with mean age 26.32 years. Majority of the participants were from rural areas (94%), married (58%), educated up to primary level (38%) and housewife (40%). 60.7% of ATPD had stressful life events (P =0. 000)which was higher than the stressful life events in patient with Schizophrenia (P =0. 005). There was a positive correlation between stressful life events and gender, setting, socioeconomic status and Diagnosis (P <0.05). Conclusion: Results show the relevance of presence of stressful life events as a potent source of perceived stress in first episode psychosis sample. Therefore this study highlights the importance of psychosocial intervention in this vulnerable group for management of illness and might be an important strategy for prevention.

Case–control study of risk factors for suicide attempts in Isfahan, Iran

2017 ◽  
Vol 63 (2) ◽  
pp. 109-114 ◽  
Author(s):  
Parastoo Golshiri ◽  
Mojtaba Akbari ◽  
Abbas Zarei
Keyword(s):  
Social Support ◽  
Life Events ◽  
Religious Beliefs ◽  
Stressful Life Events ◽  
Case Control Study ◽  
Suicide Attempts ◽  
Perceived Social Support ◽  
Stressful Life ◽  
Factors Associated ◽  
Control Study

Background: Suicide is an important, preventable, public health problem worldwide, caused by the interaction of numerous environmental, biological and psychosocial factors. Aims: This study aimed to identify the factors associated with suicidal attempts in Isfahan, Iran, in 2015. Methods: In this case–control study, 175 cases who committed suicide and were admitted to emergency services were compared with 175 controls selected among outpatients from the same hospital without any history of suicide attempt. Demographic, psychosocial, personality traits, religiosity, coping skills, stressful life events, socioeconomic status and psychiatric distress were compared between groups. Multivariable logistic regression was used to identify independent risk factors for suicide. Results: Marital status, education, socioeconomic status, psychological distress, perceived social support, stress coping strategies, personality, religious beliefs, stress life events and general health condition were significantly different between groups. The regression analysis revealed that perceived social support (odds ratio (OR) = 0.962, 95% confidence interval (CI): 0.94–0.984), religious beliefs (OR = 0.923, 95% CI: 0.867–0.984) and stressful life event (OR = 1.524, 95% CI: 1.251–1.856) were significantly associated with suicide attempts. Conclusion: Our finding showed that religious beliefs, perceived social support and stressful life events are the main factors associated with suicide attempts. So, positive strategies such as improvements in life skills to control stressful life events, religiosity and perceived social support can be used to control suicide attempts.

scholarly journals Maternity “Blues”: Prevalence and Risk Factors

2008 ◽  
Vol 11 (2) ◽  
pp. 593-599 ◽  
Author(s):  
Alexandre Faisal-Cury ◽  
Paulo Rossi Menezes ◽  
Jose Júlio A Tedesco ◽  
Soubhi Kahalle ◽  
Marcelo Zugaib
Keyword(s):  
Risk Factors ◽  
Postpartum Depression ◽  
Life Events ◽  
Tobacco Use ◽  
Stressful Life Events ◽  
Married Women ◽  
Stressful Life ◽  
Factors Associated ◽  
Civil Status ◽  
Transversal Study

Objectives: estimate the prevalence and track the risk factors associated with, Maternity blues (MB).Methods: a transversal study was performed with 113 women, on the tenth day of puerperium. The following instruments were used: Pitt Scale (1968), Stein (1980), Inventory for stressful life events by Holmes & Rahe (1967), and a questionnaire with sociodemographic and obstetric data.Results: the prevalence of MB was 32.7% according to the Stein scale. In the univariated analysis, civil status and tobacco use were associated with MB. Legally married women and nonsmokers showed a risk approximately 4 times lower of experiencing the problem.Conclusions: MB was very prevalent in this sample. Obstetricians must be aware of this condition which may be associated with postpartum depression.

Are adult stressful life events associated with psychotic relapse? A systematic review of 23 studies

2020 ◽  
Vol 50 (14) ◽  
pp. 2302-2316
Author(s):  
Natasha Martland ◽  
Rebecca Martland ◽  
Alexis E. Cullen ◽  
Sagnik Bhattacharyya
Keyword(s):  
Systematic Review ◽  
Life Events ◽  
Prospective Studies ◽  
Psychotic Disorders ◽  
Stressful Life Events ◽  
Financial Burden ◽  
Stressful Life ◽  
Psychotic Symptoms ◽  
Psychotic Episode ◽  
Cross Sectional

AbstractRelapse rates among individuals with psychotic disorders are high. In addition to the financial burden placed on clinical services, relapse is associated with worse long-term prognosis and poorer quality of life. Robust evidence indicates that stressful life events commonly precede the onset of the first psychotic episode; however, the extent to which they are associated with relapse remains unclear. The aim of this systematic review is to summarize available research investigating the association between recent stressful life events and psychotic relapse or relapse of bipolar disorder if the diagnosis included psychotic symptoms. PsycINFO, Medline and EMBASE were searched for cross-sectional, retrospective and prospective studies published between 01/01/1970 and 08/01/2020 that investigated the association between adult stressful life events and relapse of psychosis. Study quality was assessed using the Effective Public Health Practice Project guidelines. Twenty-three studies met eligibility criteria (prospective studies: 14; retrospective studies: 6; cross-sectional: 3) providing data on 2046 participants in total (sample size range: 14–240 participants). Relapse was defined as a return of psychotic symptoms (n = 20), a return of symptoms requiring hospitalization (n = 2) and a return of symptoms or hospitalization (n = 1). Adult stressful life events were defined as life events occurring after the onset of psychosis. Stressful life events included but were not limited to adult trauma, bereavement, financial problems and conflict. Eighteen studies found a significant positive association between adult stressful life events and psychotic relapse and five studies found a non-significant association. We conclude that adult stressful life events, occurring after psychosis onset, appear to be associated with psychotic relapse.

Anxiety, depression and stressful life events among medical students: a prospective study in Antalya, Turkey

2001 ◽  
Vol 35 (1) ◽  
pp. 12-17 ◽  
Author(s):  
Mehmet Aktekin ◽  
Taha Karaman ◽  
Yesim Yigiter Senol ◽  
Sukru Erdem ◽  
Hakan Erengin ◽  
...  
Keyword(s):  
Medical Students ◽  
Prospective Study ◽  
Life Events ◽  
Stressful Life Events ◽  
Stressful Life ◽  
A Prospective Study ◽  
Anxiety Depression
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