scholarly journals The Impact of Testicular Loss on The Psychopathology of Young Patients: Population-Based Analysis Of 4 Million Examinees of Manpower Administration Database

2016 ◽  
Vol 9 (1) ◽  
pp. 147-147
Author(s):  
S. Lee ◽  
◽  
J. Kim ◽  
K. Moon ◽  
J. Park ◽  
...  

Objective: Patients of hypogonadism have high risk of depression and anxiety with impaired quality of life but the psychopathological impact of testicular loss without hypogonadism is rarely reported. We studied the impact of unilateral or bilateral testicular loss on psychopathology. Design and Method: We retrospectively analyzed 4 million cases of Manpower Administration (MA) database for the evaluation of the psychopathological status of men with testicular loss. For screening psychopathological status, we used the Military Multiphasic Personality Inventory (MMPI). The examinees of testicular loss were defined at least 50% decrease of testicular volume at CT scan. The examinees without severe medical disability were classified as normal control group. The abnormal result of MMPI scale was defined as a score more than one standard deviation. Results: In this cross-sectional study, total 3932 unilateral testicular absent examinees (UTAE) and 203 bilateral testicular absent examinees (BTAE) were screened. After exclusion of examinees with abnormal response, total 3562 UTAEs and 171 BTAEs were included for final analysis. The abnormal rate of anxiety (15.5% vs. 9.5%), depression (18.3% vs. 10.6%), somatization (18.6% vs 8.7%) and personality disorder (16.8% vs. 13.7%) were higher in UTAE group than matched control. The abnormal rate of depression (18.3% vs. 15.8%) and somatization (18.6% vs. 12.6%) in UTAE group were even higher than in BTAE group. Conclusions: Our population based study suggests young patients with testicular loss are psychopathological vulnerable condition. More active psychopathological screening is indicated for young testicular loss patients.

2020 ◽  
Author(s):  
Ελισάβετ Ντουντουλάκη

Suicide is a worldwide phenomenon and is a major problem in social and health care. For many decades, there has been a growing interest in developing suicide prevention strategies. Suicide is recognized as a serious, worldwide public health concern and has been proven to be the tenth leading cause of death worldwide. The approximate international burden of suicide is one million deaths a year and public awareness is needed to effectively prevent suicide. Suicide rates varyby region and country, and the risk of suicide varies according to gender, age, employment status and quality of physical and mental health. A considerable number of substantial studies have been conducted to investigate risk factors that predict suicidal ideation and behavior. In particular, studies have shown that demographic factors such as gender and age have been found to be essential risk factors associated with suicide. Numerous studies have also investigated the association between chronic medical disease and Greek financial crisis with the existence and increased risk of suicidal behavior. The cross-sectional study had the following objectives: 1) To evaluate mental stress, suicide beahavior, patients' illness perception, sence of coherence, resilienceand religiousness of patients with chronic medical diseases. The prospective study had the following objectives: 1) to assess the course of mental stress and quality of life of patients with chronic medical diseases during a semester 2) to identify the factors associated with suicide behavior in the overall sample but also separately in patients and in the control group 3) to identify factors for improving suicide beahior in patients and in the control group 4) to identify factors affecting the relationship of suicide behavior with perceived influence of financial crisis. In the cross-sectional study participated 821 subjects, 629 of whom were in the group of patients with chronic medical diseases and 129 in the control group. In the prospective study, 464 patients with chronic medical diseases and 110 healthy subjects participated in the first phase of the study, participated in the second assessment 6 months later. The data were collected through semi-structured psychiatric interview, as well as by completing questionnaires. The findings of the 150 study showed a high prevalence of major depressive disorder, suicidal ideation and behavior and Generalized Anxiety Disorder (GAD) in patients with chronic medical diseases visiting the University Hospital of Ioannina during the Greek financial crisis. At the same time, a significant proportion of the healthy sample had depressive symptoms, however smaller than the patient sample. In addition, the results ofcurrent research verify the association between chronic physical illness and comorbidity with major depressive disorder and suicidal behavior. In addition, analyses occurred six months after baseline found that all outcomes (ie, severity of depressive symptom, risk of suicide, quality of life relatedto health) were significantly improved. The results of the prospective study on factors related to suicidality during follow-up showed that psychiatric history was significantly associated with suicidality in the overall sample of patients and healthy subjects (control group) participated in the study. Specifically, the high RASS Suicide Score and the diagnosis of depression (PHQ> 10) at baseline seem to be positively correlated with suicide scores on the follow up. On the contrary, depression improvement is negatively related to suicide on follow up assessment. Regarding theimprovement of suicide in the patient sample, three variables were found statistically significant: RASS suicidality and PHQ-9 depression diagnosis at baseline, and improvement in depression measured with the PHQ-9 scale during 6 months. These variables are same with the variables identified as important for predicting suicidality in the second measurement after a 6-month follow-up throughout the study sample. In the healthy population sample, age, diagnosis of depression (PHQ>10), and lower RASS scores were found to be negatively correlated with improved suicidality. Finally, the most important new finding is that the impact of the current financial crisis is linked to the risk of suicide, but this correlation is moderated by the presence of a psychiatric disorder: the greater the impact of the crisis, the greater the risk of suicide only when a psychiatric disorder or generalized anxiety disorder is diagnosed. In this light, as the rates of depression, anxiety disorder, and suicide in patients with chronic medical diseases were significant in the present study,clinicians should be aware that referral for psychiatric intervention is important in patients with chronic medical diseases.


2017 ◽  
Vol 2 (4) ◽  
pp. e020478
Author(s):  
Marta Dzhus

Background Young adults with juvenile idiopathic arthritis (JIA) often have an active disease with significant functional impairment in adulthood that can affect their physical and mental functions Aim To determine the impact of JIA on quality of life (QoL) in young adults with JIA during the transition healthcare Materials and methods The cross-sectional study of 89 young adults aged 16 to 22 years with a history of JIA regardless of the presence or absence of active inflammation at the time of the survey was performed in the Oleksandrivsky Central Clinical Hospital in Kyiv, Ukraine in the period between April 2015 and February 2017. 25 age- and sex-matched controls (without rheumatic disease) were included. There was performed an evaluation of the age at disease onset, duration, JIA activity, received therapy and quality of life Results Out of 89, 37 (41,6%) patients were considered to be in remission. Juvenile idiopathic arthritis had a large impact on the physical scales of quality of life. Patients with JIA had worse (p <0.001) physical health in comparison with the control group. The pain was the most important factor affecting the quality of life in cases of juvenile idiopathic arthritis. The indices responsible for the physical (p<0.001), role (borderline significance, p=0.04) functioning, and intensity of pain (p<0.001) were decreased, compared with the control group. However, the indicators responsible for psychological function in patients with JIA did not differ from the control group. The correlation analysis revealed significant negative association between disability severity (HAQ) and physical function (r=-0,56, p<0.001), role function (r=-0,33, p<0.001), pain intensity (r=-0,60, p<0.001), general health (r=-0,40, p=0.01), vital activity (r=-0,46, p<0.001), social function (r=-0,48, p<0.001), mental health (r=-0,42, p<0.001) Conclusion In our transitional cohort of patients at the era of biological therapies, juvenile idiopathic arthritis had a larger effect on the physical than mental SF-36 subscale. The pain was the main factor influencing the quality of life


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
D B O Souza ◽  
L P Barbosa ◽  
P A Santini ◽  
M B A Barros ◽  
M G Lima

Abstract Background Repetitive Strain Injury (RSI)/Work-related Musculoskeletal Disorders (WMSD) and tendonitis are considered a serious problem in the area of Occupational Health. The present study aims to estimate the prevalence of these disorders on the adult population of a metropolis in the state of São Paulo and to analyze their impact on Health-Related Quality of Life (HRQoL), according to gender. Methods A population-based cross-sectional study was conducted using data from the “Campinas City Health Survey (ISACamp 2014/15)”. The sample consisted of 2,166 individuals aged 18 years or older and the SF-36 instrument was used for HRQoL analysis. The association between the variables was verified by the chi-square test and the Poisson simple and multiple regression models were used to estimate the prevalence ratios (PR). In HRQoL estimates, the average SF-36 scores were calculated according to the independent variables. Results The prevalence of tendonitis and RSI/WMSD was 8.5%, with 6.7% tendonitis and 2.7% RSI/WMSD. The prevalence was higher among women (11%; 1.34-2.56), on individuals aged between 40-59 years (PR = 3.63; 2.28-5.80), who were on occupational activity (PR = 2.04; 1.12-3.68) or on work leave (PR = 7.07; 2.77-18.03) and on the most educated (PR = 2.45; 1.28-4.70). Subjects with these morbidities decreased in 6 of the 8 HRQoL domains and on stratification by gender, we observed that women had greater decreases in mental component scores in the presence of RSI/WMSD and men in physical component (p &lt; 0.05). Conclusions The diseases analyzed can affect men and women differently, and it is essential to consider the peculiarity of the impact between the sexes in the elaboration of interventions and preventive measures aimed at improving the quality of life. Key messages No population-based studies were found that assess the impact of RSI/WMSD on HRQoL, according to gender differences, showing the relevance of this study. It is very important to understand how these diseases affect men and women differently so that specific and more effective preventive and rehabilitative measures can be carried out.


2013 ◽  
Vol 16 (3) ◽  
pp. 748-762 ◽  
Author(s):  
Luisa Sorio Flor ◽  
Mônica Rodrigues Campos ◽  
Josué Laguardia

This study investigates whether occupation, variable that reflects social position, is associated with good quality of life among Brazilians. It is a cross-sectional study based on data obtained from a population-based survey carried out in Brazil in 2008. The sample composed of 12,423 Brazilians, older than 20 years. Physical and mental quality of life were both measured by SF-36 and scores were grouped in "above the mean" and "below the mean" to set binary outcomes. Logistic regression analysis was carried out to verify the impact of occupational position on the chances of better physical and mental quality of life, controlling it by socio-demographic and health variables. Results showed that Brazilians included on the labour market have better chances of a good physical and mental quality of life, even if controlled by other variables.


2018 ◽  
Vol 31 (3) ◽  
Author(s):  
Jolanta Majer ◽  
Sandra Pyda ◽  
Jerzy Robert Ladny ◽  
Antonio Rodriguez-Nunez ◽  
Lukasz Szarpak

2018 ◽  
Author(s):  
Dave L Dixon ◽  
William L Baker

BACKGROUND The impact and quality of a faculty members publications is a key factor in promotion and tenure decisions and career advancement. Traditional measures, including citation counts and journal impact factor, have notable limitations. Since 2010, alternative metrics have been proposed as another means of assessing the impact and quality of scholarly work. The Altmetric Attention Score is an objective score frequently used to determine the immediate reach of a published work across the web, including news outlets, blogs, social media, and more. Several studies evaluating the correlation between the Altmetric Attention Score and number of citations have found mixed results and may be discipline-specific. OBJECTIVE To determine the correlation between higher Altmetric Attention Scores and citation count for journal articles published in major pharmacy journals. METHODS This cross-sectional study evaluated articles from major pharmacy journals ranked in the top 10% according to the Altmetric Attention Score. Sources of attention that determined the Altmetric Attention Score were obtained, as well each articles open access status, article type, study design, and topic. Correlation between journal characteristics, including the Altmetric Attention Score and number of citations, was assessed using the Spearman’s correlation test. A Kruskal-Wallis 1-way analysis of variance (ANOVA) was used to compare the Altmetric Attention Scores between journals. RESULTS Six major pharmacy journals were identified. A total of 1,376 articles were published in 2017 and 137 of these represented the top 10% with the highest Altmetric Attention Scores. The median Altmetric Attention Score was 19 (IQR 15-28). Twitter and Mendeley were the most common sources of attention. Over half (56.2%) of the articles were original investigations and 49.8% were either cross-sectional, qualitative, or cohort studies. No significant correlation was found between the Altmetric Attention Score and citation count (rs=0.07, P = 0.485). Mendeley was the only attention source that correlated with the number of citations (rs=0.486, P<0.001). The median Altmetric Attention Score varied widely between each journal (P<0.001). CONCLUSIONS The overall median Altmetric Attention score of 19 suggests articles published in major pharmacy journals are near the top 5% of all scientific output. However, we found no correlation between the Altmetric Attention Score and number of citations for articles published in major pharmacy journals in the year 2017.


BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hui-Yin Yow ◽  
John Jeh Lung Tiong ◽  
Chun-Wai Mai ◽  
Esther van der Werf ◽  
Zulkifli Md Zainuddin ◽  
...  

Abstract Background Nocturia is widely prevalent condition with detrimental effects on quality of life and general health. In Malaysia, there is a lack of up-to-date prevalence study on nocturia. This study aimed to investigate the prevalence of nocturia and awareness pertaining to nocturia among Malaysian adults. Methods A cross-sectional population-based study was conducted among Malaysian adults aged ≥ 18 years old. The data was collected by mixed mode self-administered questionnaire from May 2019 to September 2019. Nocturia was defined as one or more voids at night. Results There were a total of 4616 respondents with 74.5% of response rate. The overall prevalence of nocturia among Malaysian adults was found to be 57.3%. In multivariate analysis, respondents aged 31–40 (1.91 [1.52–2.40]) or > 60 years old (2.03 [1.48–2.71]), and those who presented with hypertension (2.84 [2.28–3.53]), diabetes mellitus (1.78 [1.42–2.25]), renal disease (3.58 [1.93–6.63]) or overactive bladder (1.61 [1.10–2.35]) were associated with higher prevalence of nocturia. A significantly lower disease prevalence (p < 0.05) was noted among those aged 41–50 (0.73 [0.59–0.91]), male (0.78 [0.69–0.88]) and Chinese (0.47 [0.30–0.74]) or Indian (0.34 [0.21–0.54]) ethnicities. A total of 37.3% of respondents with nocturia reported that they faced sleeping difficulty about half the time or more after waking up in the middle of night. Those who had ≥ 2 voids per night experienced significantly higher mean bother score than those who had 1 void per night (p < 0.001). Approximately half (56.7%) of all respondents were not aware that night time urination is a medical condition. Only 25.2% of respondents with nocturia had sought medical attention for their nocturia. Conclusions The prevalence of nocturia among Malaysian adults is high and strongly influenced by age, sex, race and comorbidities. However, the general awareness pertaining to nocturia being a health issue remains low among Malaysians. The findings also highlighted the impact of nocturia on sleep and the need for nocturia education to better address this disease.


2013 ◽  
Vol 70 (10) ◽  
pp. 935-939 ◽  
Author(s):  
Jelena Peric ◽  
Natasa Maksimovic ◽  
Janko Jankovic ◽  
Biljana Mijovic ◽  
Vesna Reljic ◽  
...  

Background/Aim. Acne is a common problem in adolescent children with considerable emotional and psychological effects. The aim of this study was to determine the self-reported prevalence of acne and to assess its impact on the quality of life in high school pupils in Serbia. Methods. The cross-sectional study was conducted in May 2011 in two medical high schools in Serbia. Only pupils who gave a written informed consent to participate in the study (n = 440) were asked to fill in two questionnaires: short demographic questionnaire and Cardiff Acne Disability Index (CADI), a disease-specific questionnaire measuring disability induced by acne. Internal consistency (tested by Cronbach?s alpha) and item-total score correlations (Spearman's correlation analysis) were used for reliability analyses. Results. The study population consisted of 440 pupils, 281 from Belgrade and 159 from Uzice. Among them 371 (84.3%) were girls and 69 (15.7%) boys, with similar sex distribution in Belgrade and Uzice. The total mean age of pupils was 16.48 years (SD = 0.55). Out of 440 pupils 228 (51.8%) self-reported their acne. The acne prevalence was significantly higher in pupils from Uzice (73.6%) than in those from Belgrade (39.6%). The overall mean CADI score for the whole sample was 2.87 ? 2.74, with the similar quality of life impairment in adolescents from Belgrade and from Uzice. The mean Cronbach?s alpha was 0.82. Conclusion. This study shows that the quality of life impairment due to acne is mild for the majority of the affected pupils. The Serbian version of the CADI is a reliable, valid, and valuable tool for assessing the impact of acne on the quality of life.


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