scholarly journals In Vivo Hepato-Nephroprotective Role of Nigella sativa Seed Extract Against Lead Nitrate [Pb(NO3)2] Induced Toxicity in Albino Mice

2019 ◽  
pp. 1262-1270
Author(s):  
KÜRŞAD YAPAR ◽  
KÜLTİĞİN ÇAVUŞOĞLU ◽  
EMİNE YALÇIN ◽  
ALİ ACAR ◽  
BARAN SEVEN
Keyword(s):  
Nigella Sativa ◽  
Lead Nitrate ◽  
Seed Extract ◽  
Albino Mice ◽  
Nigella Sativa Seed

Nigella sativa Seed Extract in Green Synthesis and Nanocomposite

2020 ◽  
pp. 179-190
Author(s):  
Raya Soltane ◽  
Dalila Mtat ◽  
Amani Chrouda ◽  
Noof Alzahrani ◽  
Youssef O. Al-Ghamdi ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Nigella Sativa ◽  
Seed Extract ◽  
Nigella Sativa Seed

scholarly journals Comparison of Antibacterial Efficacy of Fenugreek Seed Extract Rinse and Nigella Sativa Seed Extract Rinse against Streptococcus Mutant Colonies

2021 ◽  
pp. 79-86
Author(s):  
Nasima Iqbal ◽  
ATA UR Rehman ◽  
Syeda Amber Zaidi ◽  
Kiran Khan ◽  
Lubna Farooq ◽  
...  
Keyword(s):  
Nigella Sativa ◽  
Positive Control ◽  
Seed Extract ◽  
Control Group ◽  
Distilled Water ◽  
Post Hoc Analysis ◽  
Fenugreek Seed ◽  
Study Participants ◽  
Post Hoc ◽  
Nigella Sativa Seed

Background: Dental infections were caused by the bacterium overgrowth on the surface of the tooth, and treatment should always be set up to prevent this development.Antibiotics have long been used as a conventional antibacterial medication, but their overuse has resulted in microbes gaining resistance to many of the antibiotics, trying to make many commercialized therapeutic remedies ineffectual and resulting to infection recurrence. In this regard we aim to analyze the antibacterial activity of nigella sativa seeds’ and fenugreek seed extract rinses against S. mutans' colonies. Methodology: It was a preclinical experimental study conducted at Baqai Medical and Dental College Karachi., from January - June 2021. Calculated sample size was n = 80 Consecutive sampling technique was used. Plaque of study participants was collected on sterile strips that was transported to laboratory for culture in sterile containers.The extract of Fenugreek seed and nigella sativa seed was kept in an airtight bottle and stored in a refrigerator till usage. The extracts were diluted in distilled water in 1:4 (Extract: Distilled water). Study participants were instructed to not brush their teeth before sampling. Study participants were divided into four groups (negative control, positive control, fenugreek seed extract group and Nigella sativa group) each group had 20 participants. Diluted Fenugreek seed extract and Nigella sativa extract was given to experimental groups for rinses. Results: There was significant decrease in number of colonies in positive controls, fenugreek seed extract group and nigella sativa extract group and there was no change in number of colonies in control group. Furthermore, the analysis showed significant (p-value = 0.001) difference among the groups followed by post hoc analysis. Post hoc analysis showed no difference between positive control, fenugreek seed extract group and nigella sativa group. Conclusion: Fenugreek seed extract and Nigella Sativa seed extract showed comparable antibacterial properties. Also, the effect was found to be similar to commercially available mouth rinse.

scholarly journals Effect of Nigella sativa seed extract on carbon tetrachloride-induced hepatotoxicity in rats

2012 ◽  
Vol 2 (4) ◽  
pp. 107-113 ◽  
Author(s):  
Nandhini Krishnan ◽  
Suriyavathana Muthukrishnan
Keyword(s):  
Carbon Tetrachloride ◽  
Nigella Sativa ◽  
Seed Extract ◽  
Nigella Sativa Seed

Green synthesis, characterization and photocatalytic activity of silver nanoparticles synthesized with Nigella Sativa seed extract

2021 ◽  
Vol 763 ◽  
pp. 138218
Author(s):  
Kishore Chand ◽  
Cheng Jiao ◽  
Muhammad Nazim Lakhan ◽  
Ahmer Hussain Shah ◽  
Vinod Kumar ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Photocatalytic Activity ◽  
Green Synthesis ◽  
Nigella Sativa ◽  
Seed Extract ◽  
Nigella Sativa Seed

The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients

2007 ◽  
Vol 21 (5) ◽  
pp. 559-566 ◽  
Author(s):  
Mohammad Hossein Boskabady ◽  
H. Javan ◽  
M. Sajady ◽  
H. Rakhshandeh
Keyword(s):  
Nigella Sativa ◽  
Seed Extract ◽  
Prophylactic Effect ◽  
Asthmatic Patients ◽  
Nigella Sativa Seed

scholarly journals Nigella sativa seed extract protects against cadmium-induced cardiotoxicity in rats

2020 ◽  
Vol 10 (1-s) ◽  
pp. 174-177
Author(s):  
Ikenna Kingsley Uchendu ◽  
Ebuka Bitrus Nnedu ◽  
Ifeoma Blessing Ekeigwe
Keyword(s):  
Histopathological Examination ◽  
Nigella Sativa ◽  
Intraperitoneal Administration ◽  
Negative Control ◽  
Seed Extract ◽  
Albino Rats ◽  
High Dose ◽  
Protective Effects ◽  
Oral Group ◽  
Nigella Sativa Seed

Objective:  The aim of this study is to investigate the protective effects of methanolic extract of Nigella sativa (MENS) (Black seed) against cardiotoxicity of cadmium in albino rats.  Methods: Twenty five (25) male albino rats, weighing (150-170g), were randomly grouped into five groups: A-E. Group B (Negative Control) received intraperitoneal administration of cadmium chloride (CdCl2, 5mg/kg) only, group C received CdCl2 and low dose MENS (300mg/kg, oral), group D received CdCl2 and high dose MENS (600mg/kg, oral), group E (Positive control) received CdCl2 and Vitamin C (200mg/kg, oral), for 7 days. No treatment was administered to group A (Normal control). Cardiac injury was assessed by measuring serum levels of Aspartate aminotransferase (AST), Lactate dehydrogenase (LDH) and Creatine kinase (CK-MB) using standard methods. The heart was harvested for histopathological examination. Results: CdCl2 induced significant cardiotoxicity with marked elevation in the levels of biochemical markers of cardiac functions (p<0.05 or p<0.01); these were however attenuated by MENS. Histopathological examination of the heart sections supported the biochemical findings. Conclusion: Nigella sativa seed extract is potentially cardioprotective against harmful chemical toxins such as cadmium. Keywords: Cadmium, CdCl2, Nigella sativa, Medicinal food, cardiotoxicity

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