Incorporation of Alginate/Chitosan Nano capsules Loaded with Sesame Oil or Omega-3 Oil in Cellulose Fabrics for Wound Healing Bandage

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Aya Sedik ◽  
mohamed mosaad ◽  
Hanan Othman ◽  
Amina Mohamed
Keyword(s):  
Wound Healing ◽  
Sesame Oil ◽  
Omega 3 ◽  
Cellulose Fabrics

scholarly journals The Effectiveness Test of Oil Phase Ointment Containing Snakehead Fish (Channa striata) Extract on Open Stage II Acute Wounded Wistar Strain Male Rats

2017 ◽  
Vol 22 (2) ◽  
pp. 97 ◽  
Author(s):  
Fransisca Daisa ◽  
Mohamad Andrie ◽  
Wintari Taurina
Keyword(s):  
Wound Healing ◽  
Healing Process ◽  
Negative Control ◽  
Stage Ii ◽  
Male Rats ◽  
Wound Healing Process ◽  
Omega 3 ◽  
Significant Difference ◽  
Healing Power ◽  
Channa Striata

The snakehead (Channa striata) contained fatty acids omega-3 and omega-6 are useful as nutrients in accelerating the wound healing process. This study aims to determine the effectiveness of the oil phase extract ointment snakehead in the healing of acute wounds open stage II. Testing the effectiveness of wound healing using 6 groups: normal, gel bioplacenton (positive control), ointment base (negative control), ointments snakehead extract oil phase concentration of 10; 20 and 40% of the 4 rats with acute wounds open stage II and observation until day 16 injury. The area of the wound was measured with the image J program Macbiophotonic, calculated% healing power, and AUC values. A statistical test to the total AUC values per rat with SPSS for Windows 22.0 program using One Way ANOVA and Post-hoc LSD test. The results showed a significant difference in the negative group with ointment concentration of 20% (p <0.05). The treatment group phase ointment fish oil extract is effective for wound healing is best to have a concentration of 20% for percentage of wound healing power of 97.157% and the average AUC value of 865.683% of the day.

Topical application of omega-3-, omega-6-, and omega-9-rich oil emulsions for cutaneous wound healing in rats

2018 ◽  
Vol 9 (2) ◽  
pp. 418-433 ◽  
Author(s):  
Wan Maznah Wan Ishak ◽  
Haliza Katas ◽  
Ng Pei Yuen ◽  
Maizaton Atmadini Abdullah ◽  
Mohd Hanif Zulfakar
Keyword(s):  
Wound Healing ◽  
Topical Application ◽  
Cutaneous Wound Healing ◽  
Omega 3 ◽  
Cutaneous Wound ◽  
Omega 6 ◽  
3 Omega ◽  
Oil Emulsions

scholarly journals Role of Arginine and Omega-3 Fatty Acids in Wound Healing and Infection

2014 ◽  
Vol 3 (11) ◽  
pp. 682-690 ◽  
Author(s):  
J. Wesley Alexander ◽  
Dorothy M. Supp
Keyword(s):  
Fatty Acids ◽  
Wound Healing ◽  
Omega 3 Fatty Acids ◽  
Omega 3

Preparation and Comparison of Effects of Different Herbal Oil Ointments as Wound-Healing Agents

2019 ◽  
Vol 207 (3-4) ◽  
pp. 177-186 ◽  
Author(s):  
Alireza Valizadeh ◽  
Mahdieh Shirzad ◽  
Mohammad Reza Pourmand ◽  
Maryam Farahmandfar ◽  
Hassan Sereshti ◽  
...  
Keyword(s):  
Wound Healing ◽  
Healing Process ◽  
Dorsal Surface ◽  
Inflammatory Cells ◽  
Hair Follicles ◽  
Sesame Oil ◽  
Full Thickness ◽  
Olive Oils ◽  
Complex Process ◽  
And Control

Wound healing is a complex process and some agents have been reported to accelerate it. The aim of this study was to evaluate the healing effect of Eucerin-based ointments of lemon, sesame and olive oils on infected full-thickness wounds in rats. Wounds were created on the dorsal surface of Male Albino Wistar rats (n = 12). Wounds were treated with an Eucerin-based ointment containing either of lemon, sesame or olive oils (33% w/w) twice a day for 14 days. Histopathology results showed that contraction of wounds treated with lemon and sesame oils was higher than in the olive oil and control groups on days 10 and 14. In the lemon- and sesame-oil treated groups, on day 14, 50% of rat lesions were completely healed. Total number of inflammatory cells in lemon oil treatment group was significantly smaller than that of others on day 14 (p < 0.001). Also, thickness of the epidermal layer and rejuvenation of the hair follicles and other skin appendages was normal in lemon and sesame oil treated groups. The lemon and sesame oil ointments accelerated the healing process of wounds in macroscopic, morphological and morphmetrical analyses. Therefore, lemon and sesame oil ointments could be considered as alternative dressings for infected full-thickness wounds because of improved wound healing characteristics.

scholarly journals Pro-Resolution Potency of Resolvins D1, D2 and E1 on Neutrophil Migration and in Dermal Wound Healing

Nano LIFE ◽  
2017 ◽  
Vol 07 (01) ◽  
pp. 1750002 ◽  
Author(s):  
Riyesh Menon ◽  
Paulina Krzyszczyk ◽  
François Berthiaume
Keyword(s):  
Wound Healing ◽  
Neutrophil Migration ◽  
Treated Group ◽  
Omega 3 ◽  
Excessive Pressure ◽  
Macrophage Phagocytosis ◽  
Strong Linear Correlation ◽  
Excisional Wound

An exuberant inflammatory response may exacerbate the primary tissue damage caused by injuries to the skin due to burns, surgery, excessive pressure, and other etiologies, thus increasing the time to heal. We hypothesized that application of factors that decrease inflammation would allow the skin to more quickly restore its barrier function, and promote the return to homeostasis. Resolvins are endogenous, pro-resolving lipid mediators derived from omega-3 fatty acids that serve to inhibit neutrophil migration and enhance macrophage phagocytosis, thus promoting the resolution of inflammation and the beginning of the proliferative phase of wound healing. Resolvins are derived either from docosahexaenoic (D-series) or eicosapentaenoic (E-series) acid. Herein, we compare the effects of resolvins D1 (RvD1), D2 (RvD2) and E1 (RvE1) on their abilities to inhibit neutrophil migration in vitro and to promote wound healing in vivo. In Transwell experiments, all resolvins inhibited neutrophil migration, with RvE1 being the most effective at a 2000[Formula: see text]nM concentration. In an in vivo murine excisional wound (1[Formula: see text]cm[Formula: see text][Formula: see text][Formula: see text]1[Formula: see text]cm) healing model, topically applied resolvins accelerated wound closure. RvE1-treated wounds healed by 19.4[Formula: see text][Formula: see text][Formula: see text]1.5 days post-wounding, which was significantly shorter than the RvD2-treated and RvD1-treated groups ([Formula: see text]0.05), which closed by an average of 22.8[Formula: see text][Formula: see text][Formula: see text]1.8 and 24.4[Formula: see text][Formula: see text][Formula: see text]2.2 days, respectively. Furthermore, all resolvin-treated groups healed faster than vehicle controls ([Formula: see text]0.05), which closed at 28.6[Formula: see text][Formula: see text][Formula: see text]1.5 days. There was a strong linear correlation ([Formula: see text]0.9384) between each resolvin’s potency in inhibiting neutrophil migration in vitro versus accelerating wound healing in vivo. Furthermore, upon histological analysis, the RvE1-treated group exhibited more mature collagen organization and re-epithelialization.

Lipid Emulsion Enriched in Omega-3 PUFA Accelerates Wound Healing: A Placebo-Controlled Animal Study

2017 ◽  
Vol 42 (6) ◽  
pp. 1714-1720 ◽  
Author(s):  
Yi-Chi Peng ◽  
Fwu-Lin Yang ◽  
Yi-Maun Subeq ◽  
Chin-Chieh Tien ◽  
Yann-Fen C. Chao ◽  
...  
Keyword(s):  
Wound Healing ◽  
Animal Study ◽  
Lipid Emulsion ◽  
Omega 3

scholarly journals PENGARUH PEMBERIAN MINYAK IKAN LEMURU (Sardinella Longiceps) SECARA SISTEMIK TERHADAP JUMLAH OSTEOBLAS PADA PROSES PENYEMBUHAN SOKET GIGI

DENTA ◽  
2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Eddy Hermanto ◽  
Soemartono Soemartono ◽  
Dwi Surya Sudrajat
Keyword(s):  
Wound Healing ◽  
Fish Oil ◽  
Tooth Extraction ◽  
Control Group ◽  
Omega 3 ◽  
Control Group Design ◽  
Tooth Socket ◽  
Post Test ◽  
Socket Healing ◽  
Sardinella Longiceps

<pre><em><strong>Background</strong>: Sockets healing is a dynamic, continuous and overlapping process. Osteoblasts are important cells in healing sockets that will mineralize into bone until the injured tissue heals. Lemuru fish oil (Sardinella longiceps) contains omega 3 which can increase the number of osteoblasts so that it accelerates the process of socket healing after tooth extraction. <strong>Objective</strong>: To determine the effect lemuru fish oil that given systemically in increasing the number of osteoblasts in post-extraction tooth socket wound healing. <strong>Materials and methods</strong>: Experimental research laboratories with post test only control group design. Samples of 33 male Wistar mice were divided randomly into 3 groups. Group K as a control group that was not given lemuru fish oil, group P1 as a group given lemuru fish oil 1.5ml / 200g BB, and P2 group as a group given 1 ml / 200g BB lemuru fish oil. Extraction of left mandibular first incisor was carried out, then extract was given once a day for 7 days with gastric sonde. Observations were made on the 14th day after tooth extraction by calculating the number of osteoblasts in the histology sample using HE (Hematoxylin Eosin). <strong>Results</strong>: In each treatment group there were significant differences (P &lt;0.05) and significant comparisons (P&gt; 0, 05). <strong>Conclusion</strong>: Giving lemuru fish oil can increase the number of osteoblasts to post-extraction tooth socket wound healing.</em></pre><p><em> </em></p>

scholarly journals Uporabnost maščobnih kislin omega-3 pri obravnavi ran na koži

2015 ◽  
Vol 49 (1) ◽  
Author(s):  
Dominika Vrbnjak ◽  
Majda Pajnkihar ◽  
Tomaž Langerholc
Keyword(s):  
Wound Healing ◽  
Fatty Acid ◽  
Fish Oil ◽  
Polyunsaturated Fatty Acid ◽  
Omega 3

Uvod: Namen članka je prikazati analizo podatkov o učinkih maščobnih kislin omega-3 na celjenje ran ter njihovo uporabnost pri obravnavi ran na koži. Metode: Za pregled literature ter analizo dobljenih virov so bile uporabljene podatkovne baze: PubMed, CINAHL, Medline in ScienceDirect. Iskanje je bilo izvedeno s ključnimi besedami v angleščini: omega-3, fish oil, polyunsaturated fatty acid (PUFA), wound, wound healing, in Boolovim operatorjem AND. V analizo so bile vključene eksperimentalne ali randomizirane klinične raziskave, objavljene v angleškem jeziku in izdane od 1993 do januarja 2014, ki so vključevale preprečevanje ali zdravljenje akutnih ali kroničnih ran na koži z uporabo maščobnih kislin omega-3. Izključitveni kriterij je bil obravnava uporabe maščobnih kislin omega-3 pri opeklinah. Iz iskalnega nabora 1151 zadetkov je bilo v podrobno analizo vključenih 15 raziskav. Rezultati: Rezultati analize literature so pokazali, da so maščobne kisline omega-3 večinoma neučinkovite pri obravnavi travmatskih in kirurških ran na koži, potencialno učinkovite pri obravnavi diabetičnih ran in učinkovite pri obravnavi razjed zaradi pritiska. Diskusija in zaključek: Protivnetni učinek maščobnih kislin omega-3 upočasnjuje in moti celjenje akutnih ran na koži, vendar lahko z njimi obvladujemo lokalne vnetne odzive in pospešujemo reepitelizacijo pri kroničnih ranah. Za oblikovanje natančnih smernic uporabe bodo potrebna nadaljnja raziskovanja.

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