Natural Approaches in Diabetes Management: A Review of Diet, Exercise, and Natural Products

2018 ◽  
Vol 24 (1) ◽  
pp. 84-98 ◽  
Author(s):  
William M. Schultz ◽  
Tina Varghese ◽  
Robert E. Heinl ◽  
Devinder S. Dhindsa ◽  
Elliot N. Mahlof ◽  
...  
Keyword(s):  
Natural Products ◽  
Diabetes Management ◽  
Lifestyle Modification ◽  
The United States ◽  
Oral Pharmacological Agents ◽  
High Quality ◽  
Pharmacological Agents ◽  
Current Therapies ◽  
Pharmacologic Treatments ◽  
Potential Interactions

Diabetes mellitus (DM) is a highly prevalent condition that causes significant morbidity and mortality in the United States and worldwide. Conventional therapies include lifestyle modification, oral pharmacological agents, and subcutaneous insulin. Emerging data suggest that natural approaches to the treatment of DM may help supplement current therapies for further glycemic control. Herein, we review the evidence of several natural modalities for DM treatment. We describe the pathophysiology of diabetes and its complications, provide an overview of current pharmacologic treatments, and finally, discuss natural approaches to diabetes management. Specifically, we will describe on the utility of diet, physical activity, and common natural products in the treatment of DM and focus on recent, high-quality studies. Adverse effects and potential interactions of each therapy will be highlighted where applicable.

scholarly journals Recent emerging gut Microbiome Management Modalities in Acute Diarrhea in Children: (a comparative study review of different probiotic strains). An Update. !

2020 ◽  
Vol 1 (6) ◽  
pp. 01-04
Author(s):  
AMR I.M. Hawal
Keyword(s):  
Comparative Study ◽  
Acute Diarrhea ◽  
Clinical Impact ◽  
Control Methods ◽  
High Quality ◽  
Oral Rehydration ◽  
Rehydration Solutions ◽  
Current Therapies ◽  
Probiotic Strains ◽  
Potential Interactions

Aims & Objectives: Acute Diarrhea (AD) is a highly prevalent condition that causes significant morbidity and mortality worldwide. Conventional therapies include oral Rehydration Solutions (ORS), Antibiotics and Zinc Products. Emerging data suggest that Probiotics use in the treatment & control of AD cases in children may help supplement current therapies for further control. Methods Herein, we review the evidence of several Probiotics modalities for AD treatment. We describe the Clinical Impact & prevalence of Acute Diarrhea in children and its complications, provide an overview of current treatments, and finally, discuss recent emergent Gut approaches to AD management. Specifically, we will describe - in a Comparative study - on the utility of different kinds of Probiotics known & used and common natural products in the treatment of Acute cases of AD and focus on recent, high-quality studies. Adverse effects and potential interactions of each therapy will be highlighted where applicable.

"Taming the Monster aka Uncontrolled Diabetes: A Viewpoint" (Preprint)

2020 ◽  
Author(s):  
Swati Anand ◽  
Amardeep Kalsi ◽  
Jonathan Figueroa ◽  
Parag Mehta
Keyword(s):  
Blood Glucose ◽  
Diabetes Management ◽  
Positive Impact ◽  
The United States ◽  
Phone Call ◽  
Diabetic Patients ◽  
Dietary Compliance ◽  
Glucose Levels ◽  
Uncontrolled Diabetes ◽  
Number Of Patients

BACKGROUND HbA1c between 6% and 6.9% is associated with the lowest incidence of all‐cause and CVD mortality, with a stepwise increase in all‐cause and cardiovascular mortality in those with an HbA1c >7%. • There are 30 million individuals in the United States (9.4% of the population) currently living with Diabetes Mellitus. OBJECTIVE Improving HbA1C levels in patients with uncontrolled Diabetes with a focused and collaborative effort. METHODS Our baseline data for Diabetic patients attending the outpatient department from July 2018 to July 2019 in a University-affiliated hospital showed a total of 217 patients for one physician. • Of 217 patients, 17 had HbA1C 9 and above. We contacted these patients and discussed the need for tight control of their blood glucose levels. We intended to ensure them that we care and encourage them to participate in our efforts to improve their outcome. • We referred 13 patients that agreed to participate to the Diabetic educator who would schedule an appointment with the patients, discuss their diet, exercise, how to take medications, self-monitoring, and psychosocial factors. • If needed, she would refer them to the Nutritionist based on patients’ dietary compliance. • The patients were followed up in the next two weeks via telemedicine or a phone call by the PCP to confirm and reinforce the education provided by the diabetes educator. RESULTS Number of patients that showed an improvement in HbA1C values: 11 Cumulative decrease in HbA1C values for 13 patients: 25.3 The average reduction in HbA1C: 1.94 CONCLUSIONS Our initiative to exclusively target the blood glucose level with our multidisciplinary approach has made a positive impact, which is reflected in the outcome. • It leads to an improvement in patient compliance and facilitates diabetes management to reduce the risk for complications CLINICALTRIAL NA

scholarly journals Natural and Nature-Derived Products Targeting Human Coronaviruses

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 448
Author(s):  
Konstantina Vougogiannopoulou ◽  
Angela Corona ◽  
Enzo Tramontano ◽  
Michael N. Alexis ◽  
Alexios-Leandros Skaltsounis
Keyword(s):  
Natural Products ◽  
Antiviral Agents ◽  
Critical Perspective ◽  
Human Coronavirus ◽  
State Of Emergency ◽  
Pharmacological Agents ◽  
Pure Compounds ◽  
Total Plant ◽  
Human Coronaviruses ◽  
The 1960S

The ongoing pandemic of severe acute respiratory syndrome (SARS), caused by the SARS-CoV-2 human coronavirus (HCoV), has brought the international scientific community before a state of emergency that needs to be addressed with intensive research for the discovery of pharmacological agents with antiviral activity. Potential antiviral natural products (NPs) have been discovered from plants of the global biodiversity, including extracts, compounds and categories of compounds with activity against several viruses of the respiratory tract such as HCoVs. However, the scarcity of natural products (NPs) and small-molecules (SMs) used as antiviral agents, especially for HCoVs, is notable. This is a review of 203 publications, which were selected using PubMed/MEDLINE, Web of Science, Scopus, and Google Scholar, evaluates the available literature since the discovery of the first human coronavirus in the 1960s; it summarizes important aspects of structure, function, and therapeutic targeting of HCoVs as well as NPs (19 total plant extracts and 204 isolated or semi-synthesized pure compounds) with anti-HCoV activity targeting viral and non-viral proteins, while focusing on the advances on the discovery of NPs with anti-SARS-CoV-2 activity, and providing a critical perspective.

The Current Status of Hearing Care: Can We Change the Status Quo?

2005 ◽  
Vol 16 (07) ◽  
pp. 410-418 ◽  
Author(s):  
Dennis Van Vliet
Keyword(s):  
United States ◽  
Hearing Loss ◽  
Care Delivery ◽  
The United States ◽  
Status Quo ◽  
Hearing Impaired ◽  
Current Status ◽  
High Quality ◽  
Scientific Database ◽  
The Status

The members of the profession of audiology often express concern that the services and products that have been developed to provide benefit to the hearing impaired are not sought after or delivered to the majority of those diagnosed with hearing loss. A critical look at the status quo of hearing care delivery in the United States is needed to verify this assumption and to develop strategies to improve the situation. A key concern is the lack of a comprehensive high-quality scientific database upon which to build continuous improvements in the effectiveness of the services and products that are provided to the hearing impaired.

Volunteers: An Effective Medium for Delivering Therapeutic Lifestyle Interventions

2021 ◽  
pp. 089011712110625
Author(s):  
Lillian M. Kent ◽  
Paul M. Rankin ◽  
Darren P. Morton ◽  
Rebekah M. Rankin ◽  
Roger L. Greenlaw ◽  
...  
Keyword(s):  
United States ◽  
Chronic Disease ◽  
Lifestyle Modification ◽  
Density Lipoprotein ◽  
Blood Lipid ◽  
The United States ◽  
Analysis Of Covariance ◽  
Health Improvement ◽  
Improvement Program ◽  
Blood Lipid Profile

Purpose Lifestyle modification programs have been shown to effectively treat chronic disease. The Coronary Health Improvement Program has been delivered by both paid professional and unpaid volunteer facilitators. This study compared participant outcomes of each mode in the United States. Design Pre-/post-analysis of CHIP interventions delivered between 1999 and 2012. Setting Professional-delivered programs in Rockford Illinois 1999-2004 and volunteer-delivered programs across North America 2005-2012. Subjects Adults ≥21 years (professional programs N = 3158 34.3% men, mean age = 54.0 ± 11.4 years; volunteer programs N = 7115 33.4% men, mean age = 57.4 ± 13.0 years). Measures Body mass index, blood pressure (systolic and diastolic), blood lipid profile (total cholesterol, high-density lipoprotein, triglycerides, low-density lipoprotein), and fasting plasma glucose. Analysis Analysis of Covariance, with adjustment for age, gender, BMI change and baseline biometric and effect sizes. Results The professional-delivered programs achieved significantly greater reductions in BMI (.4%, P < .001) and HDL (1.9%, P < .001) and the volunteer-delivered programs achieved greater reductions in SBP (1.4%, P < .001), DBP (1.1%, P < .001), TC (1.4%, P = .004), LDL (2.3%, P < .001), TG (4.0%, P = .006), and FPG (2.7%, P < .001). However, the effect size differences between the groups were minimal (Cohen’s d .1-.2). Conclusions Lifestyle modification programs have been shown to effectively treat chronic disease. The Complete Health Improvement Program (CHIP) lifestyle intervention has been delivered by both paid professional and unpaid volunteer facilitators. This study compared selected chronic disease biometric outcomes of participants in each mode in the United States. It found volunteer-delivered programs do not appear to be any less effective than programs delivered by paid professionals, which is noteworthy as volunteers may provide important social capital in the combat of chronic disease.

Safety assessment of natural products in Malaysia: current practices, challenges, and new strategies

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Nur Azra M. Pauzi ◽  
Manraj S. Cheema ◽  
Amin Ismail ◽  
Ahmad Rohi Ghazali ◽  
Rozaini Abdullah
Keyword(s):  
Natural Products ◽  
Animal Studies ◽  
Regulatory System ◽  
The United States ◽  
Regulatory Control ◽  
Health Maintenance ◽  
Traditional Medicines ◽  
Aristolochic Acids ◽  
United States Food ◽  
States Food

Abstract The belief that natural products are inherently safe is a primary reason for consumers to choose traditional medicines and herbal supplements for health maintenance and disease prevention. Unfortunately, some natural products on the market have been found to contain toxic compounds, such as heavy metals and microbes, as well as banned ingredients such as aristolochic acids. It shows that the existing regulatory system is inadequate and highlights the importance of thorough safety evaluations. In Malaysia, the National Pharmaceutical Regulatory Agency is responsible for the regulatory control of medicinal products and cosmetics, including natural products. For registration purpose, the safety of natural products is primarily determined through the review of documents, including monographs, research articles and scientific reports. One of the main factors hampering safety evaluations of natural products is the lack of toxicological data from animal studies. However, international regulatory agencies such as the European Food Safety Authority and the United States Food and Drug Administration are beginning to accept data obtained using alternative strategies such as non-animal predictive toxicological tools. Our paper discusses the use of state-of-the-art techniques, including chemometrics, in silico modelling and omics technologies and their applications to the safety assessments of natural products.

scholarly journals Lifestyle modifications: A key to manage diabetes

2020 ◽  
Vol 13 (3) ◽  
pp. 141-148
Author(s):  
Ashok B. Giri ◽  
Vishal T. Shinde ◽  
Pradip R. Lengare ◽  
Dr. Ramdas D. Shinde
Keyword(s):  
Management Strategy ◽  
Blood Sugar Level ◽  
Diabetes Management ◽  
Lifestyle Modification ◽  
Sedentary Lifestyle ◽  
Regular Exercise ◽  
Lifestyle Modifications ◽  
Effective Prevention ◽  
Abnormal Metabolism ◽  
Dietary Modifications

Diabetes is one of the leading challenges to the health care or`ganization across world. Worldwide, 422 million peoples suffering from diabetes 1. Diabetes mellitus is a metabolic disorder which is characterized by abnormal metabolism of carbohydrates, fats, protein. The main etiological factors contributes in the development of diabetes are sedentary lifestyle, obesity, intake of junk foods. It is mandatory to manage increased blood sugar level (BSL) to prevent microvascular as well as macrovascular complications. To manage diabetes, metformin and insulin play a key role hence these two medications added in the diabetes pharmacotherapy. Diabetes is not a treatable disease hence we have to maintain weight by doing regular exercise and implementation of dietary modifications. It is important to maintain the balance of daily calories intake and their utilization by practicing physical activity remain the primary and most effective prevention strategy for diabetes management. A management strategy basically involves promotion of effective weight loss and physical exercise, but it is compulsory to do exercise and follow dietary modifications regularly. This is a comprehensive review which focuses on lifestyle modifications in diabetes. How lifestyle modification play a key role in the management of both type of diabetes along with pharmacotherapy.

POLICY STATEMENT ON DAY CARE

PEDIATRICS ◽  
1973 ◽  
Vol 51 (5) ◽  
pp. 947-947
Keyword(s):  
Child Care ◽  
Day Care ◽  
The United States ◽  
Early Years ◽  
Alternative Methods ◽  
Policy Statement ◽  
High Quality ◽  
Governmental Agencies ◽  
Care Services ◽  
Family Discord

The American Academy of Pediatrics supports the continued expansion of high quality day care programs for the nation's children. It is preparing a booklet, Recommendations for Day Care Centers for Infants and Children, to serve as a guideline for establishing quality day care. The Academy also has embarked on a program to help pediatricians understand their role in fostering high quality day care. All children should have the opportunity to optimally develop their physical, intellectual, and social potential. The care and guidance they are given in their early years are of critical importance for such development. For most children, this child care and guidance are best given in their own homes, by their own families, but may need to be supplemented by child care services provided by private or governmental agencies. Because they are working, an increasing proportion of mothers are not at home to fulfill the maternal role in care and guidance. In 1971, 43% of mothers in the United States were employed: one-third of the mothers of preschool children and one-half of the single mothers of young children. For some children the home may not be the best place because of social or financial poverty or family discord which inhibit child development. Alternative methods of caring for children to help them achieve their fullest potential are needed more now than at any time in our history. Day care services should be a supplement to, not a substitute for, the family as the primary agent for the child's care and development.

Abstract 205: Does Overuse of Telemetry Impede Cost-effective Patient Care?

2020 ◽  
Vol 13 (Suppl_1) ◽  
Author(s):  
Kenneth B Brownell ◽  
Sowjanya Yenigalla ◽  
Parth Shah ◽  
Evan B Kudron ◽  
Abasin Amanzai ◽  
...  
Keyword(s):  
Quality Care ◽  
Tertiary Care ◽  
Total Duration ◽  
Heart Association ◽  
Cost Effective ◽  
The United States ◽  
Cardiac Monitoring ◽  
High Quality ◽  
Healthcare Expenditures ◽  
Evidenced Based

Background: Telemetry was first introduced in the 1950s in cardiac intensive care units (ICU) and has since expanded to beyond the ICU setting. With this expansion, concerns regarding the overutilization of telemetry have emerged. In response to these concerns, the American Heart Association (AHA) and the American College of Cardiology (ACC) released guidelines for evidenced-based telemetry utilization in 2004. Following this publication, numerous studies have shown that a significant number of non-ICU patients on telemetry do not meet evidenced-based indications leading to costly overutilization of a valuable resource. This overutilization is expensive in both the direct costs of equipment and labor as nurses spend an average of 20 minutes per patient day on telemetry related tasks. As healthcare expenditures in the United States continue to rise, efforts are needed to contain these rising costs if we wish to continue to provide high quality, affordable care. Methods: Using the electronic medical record (EMR) at our urban, tertiary-care, 482 bed teaching hospital, we performed an observational study looking at all admissions to a medical floor that were ordered telemetry in June 2019. We investigated if telemetry was ordered based upon the 2004 AHA guidelines. We then examined the total duration of telemetry utilized for non-AHA guideline indications. Next, we applied the average additional daily cost of $53.44, as reported in the literature, for monitored vs. non-monitored patients and then calculated an estimated total monthly expenditure for inappropriate use to cardiac monitoring. Annual costs were then projected based upon this figure. Results: There were 395 patients admitted in June 2019. After all inclusion criteria were applied, our sample consisted of 226 patients. Seventy-nine of these patients had telemetry ordered for an AHA guideline-based indication, while 147 patients had telemetry ordered for a non-AHA guideline indication for a total of 711 patient days, which adds $37,995.84 to monthly healthcare expenditures. Of the 147 patients that had telemetry ordered for non-AHA guideline indications, only one patient had a documented benefit, which was the detection of new-onset paroxysmal atrial fibrillation. Conclusions: Telemetry monitoring is frequently overused for patients admitted to non-critical care services. An effort to educate House Staff about the indications for ordering telemetry based on AHA guidelines can reduce healthcare-associated costs and help provide cost-effective, high-quality care to our patients.

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