scholarly journals Primary Prevention of Cardiovascular Risk in Octogenarians by Risk Factors Control

2019 ◽  
Vol 15 (2) ◽  
pp. 78-84 ◽  
Author(s):  
Pasquale Palmiero ◽  
Annapaola Zito ◽  
Maria Maiello ◽  
Annagrazia Cecere ◽  
Anna Vittoria Mattioli ◽  
...  

Primary prevention of cardiovascular events in older adults is a relevant problem, due to lack of evidence for safe and efficacious therapy, its costs and elderly quality of life, Italy’s aging population is constantly increasing, so cardiovascular disease (CVD) primary prevention in the elderly is a prime objective. Life expectancy has dramatically increased over the last 2 decades, the proportion of individuals aged 80 years and older has grown rapidly in Europe and the United States, but cost / effective ratio of CVD prevention through risk factors control is debated. It is therefore important to implement cardiovascular risk factors estimation in the elderly to maximize the quality of life of patients and to lengthen their healthy life expectancy, choosing the better treatment for each patient sharing the choice with himself when it is possible, always remembering that elderly patients often have multiple co-morbidities that require a high number of concurrent medications; this may increase the risk for drug-drug interactions, thereby reducing the potential benefits of CVD prevention therapy. Nevertheless, CVD is not an inevitable concomitant of aging. Sometimes, autopsy in the elderly reveals atheroma-free coronary arteries, a normal-sized heart and unscarred valves. All primary prevention strategy decisions should consider estimated life expectancy and overall function and not just the cardiovascular event risks, magnitude and time to benefit or harm, potentially altered adverse effect profiles, and informed patient preferences. CVD primary prevention needs to be more implemented in the elderly, this might contribute to improve health status and quality of life in this growing population if correctly performed.

Author(s):  
João Vítor Costa dos Santos Chaves ◽  
Keila Lindineia Silva Pinto ◽  
Kleicillainy Mota de Sousa ◽  
Lucas Oliveira Soares ◽  
André Luiz Lisboa Cordeiro

2019 ◽  
Vol 32 (8) ◽  
pp. 871-877 ◽  
Author(s):  
Roopa Vijayan ◽  
Nisha Bhavani ◽  
Praveen V. Pavithran ◽  
Vasantha Nair ◽  
Usha V. Menon ◽  
...  

Abstract Background The present study was designed to evaluate the metabolic profile, cardiovascular risk factors and quality of life in children with congenital adrenal hyperplasia (CAH) and compare it with age- and sex-matched controls. Methods Fifty-two patients aged 3–21 years with classic CAH due to 21-hydroxylase deficiency were included in the study. Metabolic profiling was done for 36 cases and compared with 28 healthy age- and sex-matched controls. Quality of life was assessed in all 52 children and their parents using a validated Pediatric Quality of Life Inventory (PedsQL) questionnaire and was compared with normative data from the same population. Results The median age was 12 years with 14 (27%) males and 38 (73%) females. Out of the total 52 patients, 35 (67%) had salt wasting and 17 (33%) had simple virilising CAH. The median height standard deviation score (SDS) of cases was similar to that of controls (−0.72 vs. −0.64, p = 0.57) and 81% of females had normal pubertal status indicating a good control of the disease. Weight SDS, body mass index (BMI) SDS, mean diastolic blood pressure and insulin resistance were significantly higher in cases when compared to controls (0.31 vs. −0.3; 0.96 vs. 0.17; 67.8 ± 10.49 vs. 61 ± 8.49 and 2.1 vs. 0.95, respectively). The quality of life was significantly reduced in all domains as per parents’ perspective, whereas the children reported reduced quality of social and school functioning. There was no significant correlation between quality of life and metabolic parameters. Conclusions Children with CAH despite a reasonably good control of the disease have a higher cardiovascular risk and reduced quality of life when compared to healthy controls.


Circulation ◽  
2020 ◽  
Vol 141 (7) ◽  
pp. 592-599 ◽  
Author(s):  
Anandita Agarwala ◽  
Erin D. Michos ◽  
Zainab Samad ◽  
Christie M. Ballantyne ◽  
Salim S. Virani

Cardiovascular disease (CVD) is the leading cause of death among women in the United States. As compared with men, women are less likely to be diagnosed appropriately, receive preventive care, or be treated aggressively for CVD. Sex differences between men and women have allowed for the identification of CVD risk factors and risk markers that are unique to women. The 2018 American Heart Association/American College of Cardiology Multi-Society cholesterol guideline and 2019 American College of Cardiology/American Heart Association guideline on the primary prevention of CVD introduced the concept of risk-enhancing factors that are specific to women and are associated with an increased risk of incident atherosclerotic CVD in women. These factors, if present, would favor more intensified lifestyle interventions and consideration of initiation or intensification of statin therapy for primary prevention to mitigate the increased risk. In this primer, we highlight sex-specific CVD risk factors in women, stress the importance of eliciting a thorough obstetrical and gynecological history during cardiovascular risk assessment, and provide a framework for how to initiate appropriate preventive measures when sex-specific risk factors are present.


Clinics ◽  
2008 ◽  
Vol 63 (6) ◽  
Author(s):  
Luiz Mário Baptista Martinelli ◽  
Bruno Moreira Mizutani ◽  
Anibal Mutti ◽  
Maria Paula Barbieri D'elia ◽  
Rodrigo Soler Coltro ◽  
...  

2019 ◽  
Vol 0 (Avance Online) ◽  
Author(s):  
Grace Fernanda Nunes ◽  
Luis Cuadrado Martins ◽  
Roberto Jorge da Silva Franco ◽  
Ivani Morales Xavier ◽  
Monica Marcelli de Souza ◽  
...  

Resumo Objetivo: Avaliar a associação entre nível de atividade física e fatores de risco cardiovascular, qualidade de vida e comorbidades dos pacientes hipertensos em Agudos (São Paulo - Brasil). Método: Foram avaliados 200 pacientes hipertensos e verificadas as associações entre Questionário Internacional de Atividade Física IPAQ, questionário de qualidade de vida SF-36, fatores de risco cardiovascular e comorbidades. Resultados: O nível de atividade física associou-se à qualidade de vida nos domínios capacidade funcional, limitações físicas e estado geral de saúde. Houve associação entre o nível de atividade física e qualidade de vida, mesmo ajustando-se para as variáveis de confusão (idade, sexo, profissão, acidente vascular encefálico prévio, internação previa por insuficiência cardíaca congestiva e diabetes). Conclusão: O nível de atividade física em hipertensos e diabéticos foi inferior ao desejado e associou-se a fatores de risco cardiovascular, comorbidades e vários indicadores de qualidade de vida. Resumen Objetivo: Evaluar la asociación entre nivel de actividad física y factores de riesgo cardiovascular, calidad de vida y comorbilidades de los pacientes del programa de atención a pacientes hipertensos en Agudos (São Paulo-Brasil). Método: 200 pacientes hipertensos fueron evaluados y se valoró la asociación entre el nivel de actividad física (mediante el Cuestionario Internacional de Actividad Física IPAQ), la calidad de vida (mediante el cuestionario SF-36), los factores de riesgo cardiovascular y las comorbilidades. Resultados: El nivel de actividad física se asoció con la calidad de vida en los ítems de capacidad funcional, limitaciones físicas y estado general de salud. Se obtuvo asociación entre el nivel de actividad física y dichos ítems de calidad de vida, independientemente de las variables de confusión (edad, sexo, profesión, accidente vascular encefálico previo, internamiento previo por insuficiencia cardíaca congestiva y diabetes). Conclusión: El nivel de actividad física en pacientes hipertensos y diabéticos fue menor de lo deseado y se asoció con factores de riesgo cardiovascular, comorbilidades y diversos indicadores de calidad de vida. Abstract Objetive: To evaluate the association between physical activity level and cardiovascular risk factors, quality of life, and comorbidities of hypertensive patients in Agudos (São Paulo-Brazil). Method: 200 hypertensive patients were evaluated and the associations between international physical activity Questionnaire IPAQ, questionnaire of quality of life SF-36, cardiovascular risk factors and comorbidities were verified. Results: The level of physical activity was associated with the quality of life in the areas functional capacity, physical limitations and general state of health. There was association between the level of physical activity and quality of life, even adjusting for the confounding variables. Conclusion: The level of physical activity in hypertensive and diabetic patients was lower than desired and was associated with cardiovascular risk factors, comorbidities and several indicators of quality of life.


2020 ◽  
Vol 1 ◽  
pp. 425-435
Author(s):  
Sergey Afanasyev ◽  
◽  
Sergey Rokutov ◽  
Viktoriya Proskura ◽  
Alexander Afanasieva ◽  
...  

Introduction. The data of the analysis of scientific and methodical literature on physical therapy of musculoskeletal lesions in elderly people with osteoarthritis, depending on sex, age and other risk factors are presented. Currently, osteoarthritis (OA) is a fairly common disease, especially in the elderly. As life expectancy increases, the problem becomes even more important. In Ukraine, the frequency of OA has remained quite high in recent years and continues to increase. The purpose of the study is systematization and generalization of modern scientific and methodical knowledge and practical experience in physical therapy of large joints of elderly patients taking into account risk factors. Material and Methods: analysis of special scientific methodical literature and Internet resources. Results. Chronic pain syndrome and the functional inability of the joints that accompany OA lead to a restriction of domestic physical activity and a decrease in quality of life. With age, the frequency of OA increases and among those over 65 years of age reaches 97%. Other factors include female sex, excessive body weight, low economic status, alcohol and smoking, congenital joint dysplasia, hormone changes, imbalance of cytokines. Local OA (mono- and oligoartrosis) and generalized (polyarthrosis) with the defeat of three or more joints are distinguished. Gonarthrosis is more common, because the knee joints are under constant load of body weight, more often exposed to traumatic factors. Treatment of OA using physical therapy methods is aimed at reducing pain and local inflammation, reducing the frequency of exacerbations, improving the quality of life, slowing the progression of the disease, reducing the probability of development disability of patients with this pathology. Scientists mainly pay attention to the treatment and rehabilitation of patients in the early stages of the disease. Conclusions. Many aspects of this problem have already been well studied and described. At the same time, a significant number of issues remain that require further study and discussion, in particular insufficient work on OA prevention; the problem of a differentiated approach to the development of modern rehabilitation programs for patients taking into account age, sex and complications remains incompletely investigated. Keywords: knee-joint arthrosis, aged, methods of physical rehabilitation


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