scholarly journals Wharton’s Jelly or Bone Marrow Mesenchymal Stromal Cells Improve Cardiac Function Following Myocardial Infarction for More Than 32 Weeks in a Rat Model: A Preliminary Report

2013 ◽  
Vol 8 (1) ◽  
pp. 46-59 ◽  
Author(s):  
Yelica Lpez ◽  
Barbara Lutjemeier ◽  
Kiran Seshareddy ◽  
Elizabeth M. Trevino ◽  
K. Sue Hageman ◽  
...  
Cytotherapy ◽  
2012 ◽  
Vol 14 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Sudha Balasubramanian ◽  
Parvathy Venugopal ◽  
Swathi Sundarraj ◽  
Zubaidah Zakaria ◽  
Anish Sen Majumdar ◽  
...  

FEBS Open Bio ◽  
2016 ◽  
Vol 6 (11) ◽  
pp. 1054-1066 ◽  
Author(s):  
Claire Mennan ◽  
Sharon Brown ◽  
Helen McCarthy ◽  
Eleni Mavrogonatou ◽  
Dimitris Kletsas ◽  
...  

Pharmaceutics ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1336
Author(s):  
Noelia Muñoz-Domínguez ◽  
Santiago Roura ◽  
Cristina Prat-Vidal ◽  
Joaquim Vives

Outstanding progress has been achieved in developing therapeutic options for reasonably alleviating symptoms and prolonging the lifespan of patients suffering from myocardial infarction (MI). Current treatments, however, only partially address the functional recovery of post-infarcted myocardium, which is in fact the major goal for effective primary care. In this context, we largely investigated novel cell and TE tissue engineering therapeutic approaches for cardiac repair, particularly using multipotent mesenchymal stromal cells (MSC) and natural extracellular matrices, from pre-clinical studies to clinical application. A further step in this field is offered by MSC-derived extracellular vesicles (EV), which are naturally released nanosized lipid bilayer-delimited particles with a key role in cell-to-cell communication. Herein, in this review, we further describe and discuss the rationale, outcomes and challenges of our evidence-based therapy approaches using Wharton’s jelly MSC and derived EV in post-MI management.


2015 ◽  
Vol 24 (22) ◽  
pp. 2649-2659 ◽  
Author(s):  
Mark van der Garde ◽  
Melissa van Pel ◽  
Jose Eduardo Millán Rivero ◽  
Alice de Graaf-Dijkstra ◽  
Manon C. Slot ◽  
...  

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