Pediatric Drug-Related Problems in an Indian Tertiary Care Hospital

Author(s):  
Qaiser Jahan ◽  
K. Pallavi ◽  
R. Hamshika ◽  
Varun Talla ◽  
Jupally Venkateshwar Rao ◽  
...  

Background: Improper drug usages expose patients to drug-related problems (DRPs) and can be the cause of patient morbidity and even mortality, especially frequent in hospitalized patients and pediatric groups. Objective: The objective of the present study was to identify and assess the drug-related problems in the pediatric department of tertiary care hospitals. Methods: The cross-sectional, observational study was carried out for six months included pediatric in-patients of age ≤15 years of either gender in pediatric units of tertiary care hospitals of India. The enrolled pediatric patients were observed for any drug-related problem that were further recorded and classified using the DRP registration format taken from Cipolle et al. The assessment of therapy was done by using positional statements from standard organizations and guidelines. Main outcome measure: Incidences of drug-related problems and their assessment and root cause analysis. Results: A total of 970 DRPs were identified in 296 patients, with an overall incidence of 49.3%. The incidence of DRPs was maximum in the age group of 2-12 years of children (51.2%). Patients who took six or more drugs were around eight (OR:8.41 , 95% CI: 5.22 to 13.55) times more likely to have DRPs compared to those patients who took less than six drugs. The incidences of DRPs were more in patients who were hospitalized for ≥ 7 days. Conclusion: The present study revealed significantly higher incidences of DRPs in hospitalized pediatric patients necessitating the involvement of clinical pharmacists in the pediatric department of tertiary care hospitals.

2020 ◽  
Vol 27 (11) ◽  
pp. 2492-2498
Author(s):  
Umair Tariq Mirza ◽  
Muhammad Luqman Ali Bahoo ◽  
Kanwal Ijaz

Objectives: In pediatric patients, ocular trauma is one of the most common causes of acquired blindness. This study aims to determine the epidemiology of ocular trauma in the pediatric age group, with its risk factors and consequences , visiting a Tertiary care Hospital in Mirpur Azad Kashmir. Study Design: Cross Sectional Observational study. Setting: Department of Ophthalmology at Mohammadi Teaching Hospital, Mohiuddin Islamic Medical College, Mirpur Azad Kashmir. Period: June 2016  and April 2017. Material & Methods: A cross sectional observational study was conducted in our hospital on children aged 0-10 years presenting with ocular trauma in Eye Out Patient Department. Detailed evaluation including Visual acuity, slit lamp examination and fundus assessment with 90D Lens was done. Various epidemiological parameters like age, sex distribution, place, nature, mode, object, time and type of injury along with visual acuity and treatment options were recorded. Results: Of total 40 patients most common age of presentation was 5 and 8 years. Males (72.5%) were more than females (27.5%). Out of total patients, 27 (67.5%) presented with closed globe injury as compared to open globe. Among the closed globe injury most common trauma was with wood followed by stick and fall. In cases of open globe injury, trauma with wood and scissor were common causes. Home was the most common place of injury (20 cases/ 50%), followed by park, road and school. Most frequent cause of admission and type of injury was corneal ulcer. Conclusion: Children susceptible to ocular trauma are commonly males at ages 5 and 8 years. They should not be left unsupervised even at home. Objects like wood, stick and scissors etc. should be out of reach of children. Immediate comprehensive primary management and secondary rehabilitation are mandatory in these cases.


2014 ◽  
Vol 38 (1) ◽  
pp. 15-18
Author(s):  
Mujibul Hoque ◽  
Md Muazzem Hussain ◽  
AT Reza Ahmad ◽  
Md Shahab Uddin

Objective: This study was carried out to find out the prevalence of CHD and their type among Children attended in the inpatient and out patient department of district tertiary care hospital of Sylhet. Methodology: This prospective cross sectional study was carried out in the department of Paediatrics of 4 medical college hospitals of Sylhet over a period of 1 year from January 2012 to December 2012. All children with the confirmed diagnosis of CHD with the age ranging from 1st day of life to 12 years were analyzed considering the pattern of CHD. Results: A total of 234 cases of CHD were admitted. Maximum cases of CHD were admitted between 29 days to 1year age group and 148 (63.25%) were male and the rest 86 (36.75%) were female. The male-female ration was 1.72:1. Most of the CHD (65.38%) were acyanotic and 34.42% cases were cyanotic. The commonest CHD was found VSD (33.33%) which was followed by ASD (16.24%), TOF (11.54%), Complex CHD (11.54%) and PDA (10.68%). Conclusion: It was concluded from this study that the male children are mostly sufferer from CHD and acyanotic heart disease was commonest type of CHD. DOI: http://dx.doi.org/10.3329/bjch.v38i1.20022 Bangladesh J Child Health 2014; VOL 38 (1) : 15-18


Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  

Author(s):  
Sarwat Memon

Background: The palatal rugae are special constructions that are inalterable in their position and pattern during the lifestyles of an individual. This imparts them an exceptional role in the forensic dentistry and may play potential role in malocclusion identification. This study was aimed to see association of rugae pattern with sagittal skeletal malocclusion in orthodontic patients visiting tertiary care hospital. Methods: This cross-sectional examination was completed on pretreatment records (lateral Cephalometric radiographs and maxillary dental casts) of 384 subjects at the orthodontic department of Ziauddin Dental Hospital, Karachi. The study duration was from January to July 2019. The samples were sub-divided into three sagittal skeletal groups based on ANB angle proposed by Steiner’s on lateral Cephalometric radiographs (Class I with ANB angle between 0° to 4°; Class II: ANB angle greater than 5°; Class III: ANB angle less than 0°). The shapes of three most-anterior primary rugae were then evaluated bilaterally using Kapali et al., Classification. Chi Square test was applied to find association of rugae pattern among sagittal skeletal malocclusions groups. Results: Circular and curved rugae shapes were the most prevalent in all skeletal malocclusions. The primary palatal rugae pattern was seen to be significantly different among three skeletal malocclusion groups (p<0.05). The right and left sided palatal rugae pattern showed significant difference in all three skeletal malocclusion groups (p<0.05). Conclusion: The present study showed no specific palatal rugae pattern associated with sagittal skeletal malocclusion. Further studies on larger sample and use of modern 3D technologies to scan the maxillary casts are required for results that are more precise.


Author(s):  
Nandini Chatterjee ◽  
Supratick Chakraborty ◽  
Mainak Mukhopadhyay ◽  
Sinjon Ghosh ◽  
Bikramjit Barkandaj ◽  
...  

2017 ◽  
Vol 6 (05) ◽  
pp. 5373
Author(s):  
Prabha Ponnusamy* ◽  
Radhika Katragadda ◽  
Thyagarajan Ravinder

Asymptomatic bacteriuria (ASB), most common during pregnancy is endangering as it may lead to maternal and fetal complications. Various organisms causing ASB combats the host defense mechanisms through virulence factors exhibited by them. In order to understand the pathogenesis and sequelae of infections, virulence factors like hemolysin production, gelatinase production, haemagglutination, biofilm production and many more should be identified. Hence, we aimed at studying the distribution of virulence factors among each organism causing asymptomatic bacteriuria in pregnant females attending a tertiary care hospital. Materials and Methods: This cross-sectional study was conducted in Department of Microbiology over a period of one year and six months (January 2014 to June 2015) at a tertiary care teaching hospital. A total of 1000 urine samples were included in study taken from pregnant women with asymptomatic bacteriuria. Isolation, identification of organisms was done according to standard microbiological techniques and virulence factors for individual organisms by phenotypic method were tested. Results: Out of 1000 samples screened for ASB, organisms were isolated in following frequency distribution: Escherichia coli, the commonest 54/118 (45.76%), Klebsiella pneumoniae 21/118 (17.80%), Staphylococcus aureus 19/118 (16.10%), Staphylococcus saprophyticus 10/118 (8.45%), Enterococcus faecalis 9/118 (7.63%), Pseudomonas aeruginosa 3/118 (2.54%) and Proteus mirabilis 2/118 (1.69%). Virulence factors for individual organisms and biofilm detection for all organisms were done. Conclusion: Multifactorial mechanisms determine the pathogenicity of an organism and it needs to be explored by analyzing each virulence factor and mechanism of invasion in combating the host defense systems. Hence analyzing the phenotypic expression of each virulence factor helps in better understanding about the complications of ASB.


Author(s):  
Vanajakshamma Velam ◽  
Vyshnavi Kancherla ◽  
Latheef Kasala ◽  
Anusha Kancherla ◽  
Mounica Reddy Pillaram

Abstract Background This study was an attempt to assess and compare the gender-wise lifestyle patterns and well-being status among the employees of a tertiary care teaching hospital. Material and Methods This is a cross-sectional, questionnaire-based study conducted at a tertiary care hospital between May and August 2019. A total of 777 employees belonging to both genders (male and female) and working at different professional levels were assessed. All the enrolled employees were subjected to a comprehensive study tool consisting of various dimensions of their health, which included physical, mental, social, spiritual and intellectual health dimensions. Results Among the participants, 327 (42.1%) were male and 450 (57.9%) were female. There was no significant difference in the mean age of male (37.91 ± 7.52) and female (36.85 ± 8.16) employees (p = 0.07). A significantly higher proportion of diabetes and hypertension were seen in male employees (9.8% and 14.4%, respectively) than in female (5.6% and 6.2% respectively). The overall well-being was better in male employees than in females and was statistically significant (p < 0.0001). We found that male employees had statistically significant better well-being in terms of physical, mental and social health whereas female employees had intellectual health. Conclusion The overall well-being in healthcare staff was good at our tertiary care hospital, and the outstanding/good well-being rate was higher in male employees than in female employees. Female employees experienced risks with regard to their physical health.


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