Clinical evaluation of Nasya Karma and Vatagajankusha Rasa effect in the management of Pakshaghata

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Kuldeep . ◽  
A. S. Prashanth ◽  
S. G. Chavan
Keyword(s):  
Blood Vessels ◽  
Brain Tissue ◽  
Blood Supply ◽  
Clinical Evaluation ◽  
The Other ◽  
Cerebral Blood Vessels ◽  
Modern Era ◽  
The Brain

Vata Vyadhi is considered one among the Ashta Maha Gada as told by Acharya’s. Out of all Nanatmaja Vata Vyadhis, the disease Pakshaghata is considered superior among the other Vataja disorders. In modern era, the Lakshana’s of Pakshaghata is closely resembles the disease Hemiplegia. In Hemiplegia, symptoms appears due to the Ischemia of Brain tissue which is an end result of improper blood supply to the brain either due to thrombus, embolism or may be due to rupture of any cerebral blood vessels. Acharya Bhela, has considered Pakshaghata as one among the Asthi Majjagata Roga’s. Acharya Sushruta also states that, the Mastulunga Majja is nothing but it is Majjadhara Kala. So, here an attempt has been made to evaluate the efficacy of Brimhana Nasya along with Shamanoushadi’s for the management of Pakashaghata.

scholarly journals Study of the changes in the position and the pattern of changes of the brain arteries in fetuses and full-term stillborns

2004 ◽  
Vol 4 (3) ◽  
pp. 7-10
Author(s):  
Amela Kulenović ◽  
Faruk Dilberović
Keyword(s):  
Blood Vessels ◽  
Full Term ◽  
The Other ◽  
Fetal Life ◽  
Brain Growth ◽  
Cerebral Blood Vessels ◽  
Brain Arteries ◽  
Gestation Age ◽  
Relationship Of ◽  
The Brain

We studied cerebral blood vessels in 20 fetuses of the gestation age between 16-36 weeks, and in 5 full-term stillborn cadavers by the method of dissection. One portion of the brain samples were processed by filling the blood vessels with 10% solution of formalin, whereas in the other group we used Mixobar and injected it through carotid artery to demonstrate brain arteries. In early fetal life the arteries are thin and have a straightforward pattern, which is in a direct correlation with the development of the brain. In brain arteries of a 28-week old fetus we observed progressive changes at all three brain arteries that began to assume more curved pattern. Since a significant increase in the brain growth and formation of the gyruses and sulcuses of the brain occurs in the 32nd week, the arteries also assume a wavier pattern, and the number of its branches increases. In full-term stillborns, the arteries are much larger in caliber, they branch abundantly, and due to relatively wide brain sulcuses we may also conclude that their pattern is partially tortuous. From our results it is evident that there are changes in the position, pattern and relationship of brain arteries that are parallel with the brain development and formation gyruses and sulcuses of the brain.

Morphological changes in the brain of wistar rats after insulin injection

2015 ◽  
Vol 9 (1) ◽  
pp. 0-0 ◽  
Author(s):  
Бантыш ◽  
B. Bantysh ◽  
Макишева ◽  
R. Makisheva ◽  
Субботина ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Brain Tissue ◽  
Cortical Neurons ◽  
Wistar Rats ◽  
Morphological Changes ◽  
Thrombus Formation ◽  
Visual Fields ◽  
Insulin Injection ◽  
Old Rats ◽  
The Brain

The morphological changes in the brain tissue of Wistar rats of different ages after intramuscular insulin injection in the dose of 1 IU/kg are typical for the hypoxic lesions of nervous tissue. The brain of rats at the age of 1-2 months responds to increased deposition of glycogen, moderate swelling around the cells and blood vessels. The effect of insulin on the brain Mature rats at the age of 5-7 months leads to vasodilatation, more pronounced swelling around the cells and blood vessels, hypertrophy of cells, aggregation and diabetes of red blood cells. The severity of ischemic changes significantly increased in the brain of old rats at the age of 20-24 months. These old rats had the senile dendrites, the widespread hypertrophic degenerative changes, i.e. flask-shaped vasodilation, hyperemia. In most of the visual fields are detected capillaries with the presence of aggregation on the side erythrocytes, signs of micro thrombosis, hemorrhage areas. The authors note that there is a loss of tone and tortuosity of the small arterioles, widespread swelling around the cells and around the blood vessels. Morphological signs of brain reaction on insulin injection reflect the death of cortical neurons, marked swelling of the brain tissue, disruption of vascular permeability, the thrombus formation and hemorrhages.

The Neurovascular Unit: Focus on the Regulation of Arterial Smooth Muscle Cells

2020 ◽  
Vol 16 (5) ◽  
pp. 502-515 ◽  
Author(s):  
Patrícia Quelhas ◽  
Graça Baltazar ◽  
Elisa Cairrao
Keyword(s):  
Blood Flow ◽  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Blood Vessels ◽  
Neurovascular Unit ◽  
Muscle Cells ◽  
Cerebral Blood Vessels ◽  
Mural Cells ◽  
Brain Pericytes ◽  
The Brain

The neurovascular unit is a physiological unit present in the brain, which is constituted by elements of the nervous system (neurons and astrocytes) and the vascular system (endothelial and mural cells). This unit is responsible for the homeostasis and regulation of cerebral blood flow. There are two major types of mural cells in the brain, pericytes and smooth muscle cells. At the arterial level, smooth muscle cells are the main components that wrap around the outside of cerebral blood vessels and the major contributors to basal tone maintenance, blood pressure and blood flow distribution. They present several mechanisms by which they regulate both vasodilation and vasoconstriction of cerebral blood vessels and their regulation becomes even more important in situations of injury or pathology. In this review, we discuss the main regulatory mechanisms of brain smooth muscle cells and their contributions to the correct brain homeostasis.

YOUNG INVESTIGATORS

2013 ◽  
Vol 17 (08) ◽  
pp. 53-56
Author(s):  
Geraldine Lai Dunlin ◽  
Ong Sher Lyn ◽  
See Jing Rou ◽  
Lily Yani ◽  
Lim Jia Min
Keyword(s):  
Platelet Aggregation ◽  
Blood Vessels ◽  
Blood Supply ◽  
Heart Attack ◽  
The Brain

P latelets have an important role to play in the clotting of blood. When platelet aggregation is not under control, excessive aggregation occurs, leading to theblockage of the blood vessels. Reduction in blood supply or the dislodging of clots from their site of origin may damage vital organs like the brain or heart; leading to a stroke or heart attack.

Mixed perfusion: A combined blood supply to the brain tissue by multiple arteries

2010 ◽  
Vol 37 (4) ◽  
pp. 201-210 ◽  
Author(s):  
R.P.H. Bokkers ◽  
P.J. van Laar ◽  
A. van der Zwan ◽  
W.P.Th.M. Mali ◽  
J. Hendrikse
Keyword(s):  
Brain Tissue ◽  
Blood Supply ◽  
The Brain

scholarly journals An Electro-Optical Method for Differential Diagnosis of Pathologies of Blood Supply to the Brain

Biomeditsina ◽  
2021 ◽  
Vol 17 (3) ◽  
pp. 68-73
Author(s):  
A. A. Nikolaev ◽  
N. N. Karkischenko ◽  
Yu. A. Chudina ◽  
D. B. Chaivanov ◽  
A. A. Vartanov
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Healthy Volunteers ◽  
Blood Vessels ◽  
Blood Supply ◽  
Experimental Studies ◽  
Significance Level ◽  
Cerebral Blood Supply ◽  
Simplified Method ◽  
The Brain

This work is devoted to the development of a new simplified method for express diagnostics of cerebral blood supply disorders of a vertebrogenic and non-vertebral nature based on electrocardiogram and photoplethysmogram data. The research was conducted using the example of vertebral artery syndrome in osteochondrosis of the cervical spine and somatoform dysfunction of the autonomic nervous system, respectively. Several experimental studies into the dynamics of heart rate variability and differential indicators of the coordinated work of the heart and blood vessels were carried out according to the data of electrocardiography and photoplethysmography. Three experimental groups included healthy volunteers and volunteers with cerebral blood supply disorders connected with either the loss of plasticity and narrowing of brain blood vessels or their mechanical squeezing. According to the research results, statistically significant (with a significance level of less than 0.05) differences by a number of indicators were revealed between the experimental groups. A conventional discriminant analysis of the indicators of the coordinated work of the heart and blood vessels was carried out for all experimental groups in order to determine criteria for differentiating people with vertebrogenic disorders, non-vertebral disorders and healthy volunteers. It is concluded that three variables can be used for such differentiation, each of which describes the coordinated work of the heart and blood vessels in a specific way.

scholarly journals Contribution to the knowledge of position, flow and arterial distribution of cerebral blood vessels in foetuses 4 to 9 months of age

2004 ◽  
Vol 4 (4) ◽  
pp. 59-62
Author(s):  
Amela Kulenović ◽  
Faruk Dilberović
Keyword(s):  
Brain Development ◽  
Blood Vessels ◽  
Gestational Age ◽  
Cerebral Arteries ◽  
Fetal Life ◽  
Cerebral Blood Vessels ◽  
Born Baby ◽  
Straight Flow ◽  
The Brain

We studied cerebral blood vessels in 25 fetuses of gestational age 16-36 weeks and in 10 cadavers of still-born babies by injection-corrosive method. In the early fetal life, arteries are thin with the straight flow, which is directly connected with the brain development. Progressive changes are observed in all the three cerebral arteries in 28-week old fetus, which straight flow becomes more and more tortuous. As in the 32nd week the brain develops faster and gyri and sulci are being formed, the arteries assume wavy flow and number of their rami increases. In a still-born baby, arteries are of rather bigger caliber; they branch abundantly; and due to their relatively broad cerebral sulci, it can be said that their flow is partly tortuous. Our results show evidently that position, flow and relation of cerebral arteries change concurrently with the brain development and appearance of cerebral gyri and sulci.

Irregularities in the formation of the Willis circle, their frequency and significance in the mentally ill

1901 ◽  
Vol 1 (7-8) ◽  
pp. 393-394
Author(s):  
N. A. Vyrubov
Keyword(s):  
Blood Vessels ◽  
Mentally Ill ◽  
The Other ◽  
Other Hand ◽  
The One ◽  
The Brain

Abstracts. Psychiatry.Dr. N.A. Vyrubov. Inaccuracies in the formation of the Willis circle, their frequency and significance in mentally ill patients.Review of psychiatry, neurology and experimental psychology.May, June, 1901.The author sets himself the task, on the one hand, to find out whether deviations in the formation of vessels of the Willis circle are encountered in the mentally ill more often than in the mentally healthy; on the other hand, do not the mentally ill have any or all of the arteries of the base of the brain a special tendency to deviate in education, that is, show with numbers in hand what anomalies in the formation of blood vessels are encountered most often in mentally ill.

scholarly journals ANAEROBIC GLYCOLYSIS OF THE BRAIN IN EXPERIMENTAL POLIOMYELITIS

1945 ◽  
Vol 81 (2) ◽  
pp. 151-159 ◽  
Author(s):  
Harland G. Wood ◽  
Irving I. Rusoff ◽  
John M. Reiner
Keyword(s):  
Brain Tissue ◽  
The Other ◽  
Anaerobic Glycolysis ◽  
Small Decrease ◽  
Wet Weight ◽  
Different Strains ◽  
The Brain ◽  
Experimentally Induced

The rate of anaerobic glycolysis of brain tissue was compared for normal animals and animals with experimentally induced poliomyelitis, using two different strains of mice and two different procedures. The report of interference of poliomyelitis with anaerobic glycolysis of brain was not confirmed. In one series there was a small increase and in the other series a small decrease in the brain QCOCO2N2 calculated for infected animals as compared to normal animals. When the calculations were made on the basis of wet weight of brain there was no difference in glycolysis. It is considered that the methods so far used for study of the enzymes may be inadequate, and that no decision is as yet possible on the effect of poliomyelitis on anaerobic glycolysis.

scholarly journals Morphological Features Of Microvascular Tissue Of The Brain At Hemorrhagic Stroke

2020 ◽  
Vol 02 (10) ◽  
pp. 53-59
Author(s):  
Kamalovamalika Ilkhomovna ◽  
◽  
Islamov Shavkat Eriyigitovich ◽  
Khaidarov Nodir Kadyrovich ◽  
◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Blood Vessels ◽  
Brain Tissue ◽  
Cerebral Edema ◽  
Hemorrhagic Stroke ◽  
Adverse Outcome ◽  
Morphological Features ◽  
Neuroimmune System ◽  
Younger Age ◽  
The Brain

Hemorrhagic stroke is less common than ischemic stroke and is heavier and in most cases has an adverse outcome in the form of death of a patient or permanent disability.Recently, there has been a tendency to increase the frequency of GI, which is increasingly found at a younger age. GI is based on a rupture of blood vessels, the development of hemorrhage and as a consequence - the formation of cerebral edema, ischemia of brain tissue, violation of the integrity of GBS, imbalance of the neuroimmune system, as well as violation of the function of other systems and organs.

Sign in / Sign up

Export Citation Format

Share Document