scholarly journals Physico-Chemical analysis of Gandharvahasta Taila - A Polyherbal formulation

2020 ◽  
Vol 5 (05) ◽  
pp. 255-258
Author(s):  
Sachin Seth1 ◽  
Gangaprasad Asore ◽  
Vishakha Vivek Sonawane
Keyword(s):  
Refractive Index ◽  
Chemical Analysis ◽  
Specific Gravity ◽  
Physicochemical Parameters ◽  
Dosage Form ◽  
Physicochemical Analysis ◽  
Polyherbal Formulation ◽  
Drug Of Choice ◽  
Saponification Value ◽  
Physico Chemical

Sneha Kalpana, a group of medicated Taila and Ghrita is an important dosage form described in Ayurveda. It is the only dosage form that can be administered conveniently both internally and externally depending on the diseased conditions. Among these, Taila Kalpana is considered as the drug of choice for Vatavikaras. Gandharvahasta Taila is mentioned in Ashtanga Sangraha in the context of Vidradhivrudhi Chikitsa indicated in Vidradhi, Pleeha, Vata disorders, etc. Aim: The aim of the study was to prepare and analyze the physicochemical parameters of Gandharvahastadi Taila. Materials and Methods: Gandharvahasta Taila was prepared as per the reference in Ashtanga Sangraha. The obtained product was subjected to organoleptic and physicochemical analysis. Results: Physicochemical parameters obtained are refractive index at 25°C - 1.463, saponification value - 190 mg/g, unsaponifiable matter - 1.4%, specific gravity at 30°C - 0.9201, and viscosity at 30°C - 880cp. Conclusion: The values obtained after analysis were found to be within the permissible limits of API.

scholarly journals QUALITY CHARACTERISTICS OF CASSIA SIEBERIANA L.SEED OIL

2016 ◽  
Vol 3 (3) ◽  
pp. 293-297
Author(s):  
A. A. Warra
Keyword(s):  
Refractive Index ◽  
Chemical Analysis ◽  
Iodine Value ◽  
Peroxide Value ◽  
Seed Oil ◽  
Acid Value ◽  
Quality Characteristics ◽  
Saponification Value ◽  
Physico Chemical ◽  
Soxhlet Apparatus

Oil was extracted from the seed of Cassia sieberiana Lusing soxhlet apparatus. The oil yield was 9.26±0.01% and the colour of the seed oil was dark yellow. The results of the physico-chemical analysis revealed the following; acid value, iodine value, saponification value, peroxide value, relative density and refractive index of 0.35±0.01 mgKOH/g , 135.60 ±0.10 gI2/100g, 235.62 ±0.01 mgKOH/g, 1.8 ±0.10meq H2O2 , 0.8185±0.00 (g/cm3) and 1.4415 ±5.77 respectively indicating the suitability of the seed oil for pharmaceutical and cosmetic applications.

Physico-chemical Analysis of Tangashree Ghrita

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Asha F. Hosur ◽  
Mamatha K. V. ◽  
Veena B. Kupati
Keyword(s):  
Refractive Index ◽  
Chemical Analysis ◽  
Moisture Content ◽  
Iodine Value ◽  
Acid Value ◽  
Who Guidelines ◽  
Saponification Value ◽  
Physico Chemical ◽  
Chemical Studies

Quality of the drug is basic need of the era, Analytical tests are helpful to overcome the impurity or substandard of drugs. By following these tests we can ensure the qualities of drugs and promise the good result in treating the disease. Materials and methods: Physico‐chemical studies like Refractive index, Acid value, Saponification value, Iodine value and moisture content were carried out as per the WHO guidelines, Ayurvedic Pharmacopoeia and Indian Pharmacopoeia. Conclusion: Standardization tests done on Tangashri Ghrita are useful in authentication and ensuring the quality of the same.

Quality Control Parameters of Mandukarni Syrup - A classical memory enhancing dosage form

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Almas Tarannum ◽  
Prathviraj Puranik ◽  
Suma V. Mallya
Keyword(s):  
Quality Control ◽  
Refractive Index ◽  
Specific Gravity ◽  
Dosage Form ◽  
Reducing Sugar ◽  
Standard Protocol ◽  
Direct Impact ◽  
Control Parameters ◽  
Quality Control Parameters ◽  
Memory Enhancing

Ayurveda is the healing medicine. Dosha, Dhatu, Mala and Agni play important role in maintaining health of a person, but without equilibrium of Atma, Indriya and Manas they are helpless. Manas is one entity which is the controller of health. There are several herbs which have direct impact on Manas, among them Mandukaparni is one. Swarasa of Mandukaparni is highly effective, but it is not easily available for children. This study is intended to make Syrup form of Mandukaparni and evaluate its pharmacognostical parameters. According to the methodology refractive index, total solids, specific gravity, reducing and non Reducing sugar and HPTLC parameters were assessed. The results were found to be genuine fulfilling the standard protocol. This study is under taken to evaluate the pharmacognostic properties of Mandukaparni syrup.

scholarly journals Standardisation Process of <i>Saye</i>, a Traditional Polyherbal Formulation Remedy for Malaria: Physico-chemical Analysis and Phytochemical Investigation

2020 ◽  
Vol 8 (1) ◽  
pp. 33
Author(s):  
Jules Yoda ◽  
Jean Claude Ouedraogo ◽  
Salfo Ouedraogo ◽  
Maminata Traore-Coulibaly ◽  
Felix Kini ◽  
...  
Keyword(s):  
Chemical Analysis ◽  
Polyherbal Formulation ◽  
Phytochemical Investigation ◽  
Physico Chemical

scholarly journals Modification of Kakubhadi Churna into malahara and its physicochemical analysis

2021 ◽  
Vol 12 (4) ◽  
pp. 866-872
Author(s):  
Neha Semwal ◽  
Rakshitha D ◽  
Govinda Sharma K
Keyword(s):  
Chemical Analysis ◽  
Shelf Life ◽  
Physicochemical Analysis ◽  
Dosage Forms ◽  
Raw Material ◽  
Physico Chemical

Samskara is the process of modification of Guna of a given substance which is responsible for conversion of a raw material into medicine. These Samskara are responsible for the change in quality and property of any medicine. Primary preparations of Bhaisajya Kalpana known as Panchavidha kashaya Kalpana are modified into secondary dosage forms like Vati, Avaleha, Malahara, Sneha kalpana etc in order to achieve better shelf life, easy administration and palatability. Churna kalpana is an Upkalapana of Kalka kalpana, it is mentioned to be used in many disease conditions. One among these is Kakubhadi churna, which is indicated to be sprinkled externally on Dushta Vrana. As this method of application is cumbersome and not patient friendly, an attempt has been made to modify Kakubhadi churna into Malahara. Malahara is similar to ointments and creams in modern pharmaceutics. When compared to Churna, it has as an extended shelf life and also drugs in the form of Malahara are easy to apply and store. Taking all this under consideration, present study was taken up to modify Kakubhadi churna into Malahara. Physico chemical analysis of prepared Churna and Malahara was also done to achieve preliminary standard.

scholarly journals A COMPARATIVE PHARMACEUTICO ANALYTICAL STUDY OF YASTIMADHU KSHEERAPAKOTTHA GHRITHA AND YASTIMADHU GHRITHA

2021 ◽  
pp. 129-132
Author(s):  
Dr.Ramakiran ◽  
Dr.Harshitha M
Keyword(s):  
Refractive Index ◽  
Qualitative Analysis ◽  
Clinical Research ◽  
Key Words ◽  
Analytical Study ◽  
Drug Research ◽  
Chemical Properties ◽  
Special Property ◽  
Saponification Value ◽  
Physico Chemical

Drug research is an important part of pharmaceutical field especially in Ayurveda pharmaceutics to revalidate and establish various formulations. Ghritha kalpana has got prime importance due to a special property of Ghritha i.e Samskarasyanuvartana. Ksheera ghritha and Ghritha are explained with different properties in Ayurveda classics. Present study is to compare between Yastimadhu Ksheera ghritha and classical Yastimadhu ghritha by organoleptic and analytical parameters. Ksheera ghritha procedure may bypass the long procedure , maximise the percentage of extract in Ghritha. Reference of Ksheera ghritha is available in various classical texts like Sushruta samhitha1 etc. Ksheera ghritha said to have properties like Netrya , Sangrahi , Rakthapitta hara etc. Ksheera ghritha of Yastimadhu prepared by preparing Ksheerapaka taken as G1 and Yastimadhu Ghritha prepared by normal classical way taken as G2. Analytical study for standardization of both samples were carried out on the basis of classically illustrated organoleptic tests and modern parameters of physico-chemical properties like LOD, Refractive index , Saponification value etc., and TLC done for qualitative analysis. By this study the major difference between Ksheera ghritha and Ghritha are established giving further scope for clinical research to establish efficacy of same. KEY WORDS : Ayurveda, Ghritha, Yastimadhu, Ksheerapaka.

scholarly journals Quality Characterisation and HPTLC fingerprinting of Vachadi syrup: A polyherbal formulation

2016 ◽  
Vol 5 (6) ◽  
pp. 234-237
Author(s):  
Lowkesh Chandravanshi ◽  
◽  
Chethan Kumar VK ◽  
Nagaratna Jartarghar ◽  
◽  
...  
Keyword(s):  
Refractive Index ◽  
Specific Gravity ◽  
Physical Constant ◽  
Reducing Sugar ◽  
Acorus Calamus ◽  
Bioactive Constituents ◽  
Total Solids ◽  
Polyherbal Formulation ◽  
Trachyspermum Ammi

Polyherbal formulations (PHFs) are potential for their safety, cost effectiveness and better acceptability than allopathic drugs. PHFs help in amelioration of various serious disorders. Therapeutic efficacy of herbal medicine is exerted due to the bioactive constituents of plants. The present study was aimed to prepare and standardize a polyherbal formulation (Vachadi syrup) including traditional drugs such as Acorus calamus (rhizomes), Trachyspermum ammi (fruits), Phyllanthus emblica (fruits), Terminalia bellirica (fruits), Terminalia chebula (fruits), Zingiber officinalis (rhizomes). Methods: Prepared polyherbal formulation was subjected to determine the physical constants (pH determination, refractive index, specific gravity, total solids, reducing and non reducing sugar) and HPTLC fingerprinting. Results: The analysis revealed the physical constant such as refractive index 1.43418, specific gravity 1.256, pH 3.5, total solids 61.50, total sugar 17.64 and reducing sugar 4.46. HPTLC fingerprinting profile showed different band patterns at different wavelength under short UV, long UV and at 620nm after derivatisation with vanillin sulphuric acid spraying reagent. Unique Rf patterns were recorded. Conclusion: Vachadi syrup was authenticated according to pharmacopeial standards as its analysis was important to ensure the quality of drug.

scholarly journals ANALYTICAL STUDY OF SHATAHWADI GHRITA

2020 ◽  
Vol 8 (9) ◽  
pp. 4381-4384
Author(s):  
Renu Prasad ◽  
Gunjan Sharma ◽  
Radhika Menon ◽  
Aditi 4
Keyword(s):  
Refractive Index ◽  
Iodine Value ◽  
Peroxide Value ◽  
Physicochemical Parameters ◽  
Analytical Study ◽  
Classical Method ◽  
Chemical Study ◽  
Therapeutic Impact ◽  
Polyherbal Formulation

Shatahwadi ghrita is an Ayurvedic formulation mentioned in Ashtanga hridaya in the management of Timira. The main contents of this Ghrita are Shatahwa, Nalada, Kakoli, Ksheerakakoli, Yashtimadhu, Pra-poundarika, Sarala, Pippali, Devadaru. It’s prepared by classical method of Ghrita kalpana. Aim: To prepare and do the physio-chemical study of finished product. Materials and Methods: Shatahwadi ghrita is a polyherbal formulation which is formulated by classical method of Ghrita paka. It contains drugs having properties such as Tridoshahara, Chakshushya and Ra-sayana. Results: Standardization of Shatahwadi ghrita shows remarkable results regarding Refractive index, sapon-ification value, iodine value, peroxide value etc. Conclusion: The prepared Shatahwadi ghrita matches the physicochemical parameters and can impact good therapeutic impact.

scholarly journals IMPACT OF FERMENTING AGENTS ON MARKETED PATENT PROPRIETARY FORMULATION ASHWAGANDHA KALPA

2017 ◽  
Vol 10 (16) ◽  
pp. 63
Author(s):  
Ambika Thakur ◽  
Renuka Thakur ◽  
Dileep Singh Baghel
Keyword(s):  
Refractive Index ◽  
Secondary Metabolites ◽  
Specific Gravity ◽  
Physicochemical Parameters ◽  
Total Solid ◽  
Solid Content ◽  
Quantitative Assay ◽  
Marked Variation ◽  
Alcohol Content ◽  
Total Solid Content

  Objective: The present work is aimed to formulate Ashwagandha kalpa and evaluate the impact of fermenting agent.Methods: A. kalpa is a marketed patent proprietary Ayurvedic product prepared by adopting the Ayurvedic principles of madya sandhana and it belongs to the class of formulations known as Sandhana kalpana. It is given to the patients suffering from hypertension, insomnia, paralysis, loss of concentration, etc. In the preparation of madya sandhana, the sandhana dravya (fermenting agents) play a key role. The present study was taken up to see the effect of three different sandhana dravya (fermenting agents), i.e., Dhataki pushpa (DAK), Madhuka (MAK), and yeast (YAK) on the formulation characterization of A. kalpa.Results: The prepared samples were tested for their physicochemical parameters, i.e., total solid, pH, specific gravity, sugar content, alcohol content, refractive index, phytochemical screening, quantitative assay for secondary metabolites, and high-performance thin-layer chromatography (HPTLC) fingerprinting. The findings of phytochemical evaluation, quantitative assay, and HPTLC fingerprint show marked variation among three different prepared samples of A. kalpa. The preliminary phytochemical estimation for the detection of secondary metabolites was done. The study revealed the presence of highest percentage of alkaloids in YAK, tannins in DAK and saponins in YAK. Total solid content was found to the highest in MAK. Physicochemical parameters such as pH, total solid content, refractive index, alcohol content, and specific gravity also showed marked variation. Alcohol content for the DAK and YAK was found same.Conclusion: sandhana dravya (fermenting agent) causes variations in different physicochemical and phytochemical parameters in the formulation and development of A. kalpa.

Evaluation of Physicochemical and Biodegradability Properties of Selected Nigerian Non-Edible Oilseeds as Potential Cutting Fluids

2015 ◽  
Vol 58 (3) ◽  
pp. 122-129
Author(s):  
Titilope John Jayeoye ◽  
Mary Bosede Ogundiran ◽  
David Abimbola Fadare ◽  
Adeniyi Adewale Ogunjobi
Keyword(s):  
Specific Gravity ◽  
Iodine Value ◽  
Peroxide Value ◽  
Physicochemical Parameters ◽  
Extraction Process ◽  
Mineral Oil ◽  
Oil Extraction ◽  
Cutting Fluid ◽  
Cutting Fluids ◽  
Saponification Value

This paper reports evaluation of physicochemical and biodegradability properties of selected non edible Nigerian oilseeds as a potential cutting fluid. Oil extraction process was carried on the oilseeds, with physicochemical parameters and biodegradability of the extracts were equally assessed. The established physicochemical parameters were percentage oil yield (5.58-61.8%), specific gravity (0.86-0.94), acidvalue (2.89-18.2 mgKOH/g), iodine value (15.7-104 mg iodine/g), peroxide value (1.35-10.9 mg/g oil), saponification value (173-286 mg KOH/g) and viscosity (37.9-53.1centipoises), while biodegradabilityranged between (50.0-63.8%) in comparison with the mineral oil with values less than 20%. Based on this study, the oil extracts of Caesalpinia bonduc and Calophyllum inophyllum appeared to be the most suitable as potential cutting fluids for further formulation studies and machining trials. 

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