A Comparative Study between Apamarga Pratisaraniya Kshara and Shireesha Beejadi Lepa in the management of Arsha

Author(s):  
Dr. Chandrashekhar . ◽  
Dr. Pallavi A. Hegde

Background: Arsha is fleshy projection that pains like an enemy and creates obstruction in Guda Marga which can be compared with haemorrhoids and one among the Astamahagada. Arsha presents with clinical features as bleeding per rectum, prolapse, feeling of mass, pain, anaemia. Peak age is 4rd to 6th decade while majority of patients report regarding onset of disease in 5th decade of life and increased prevalence in women compared with men. Objectives of the Study: To compare the efficacy of Shireesha Beejadi Lepa over Apamarga Pratisaraniya Kshara in the management of Arsha with special refence to Internal Haemorrhoids. Methods: 30 patients were selected on the basis of inclusion criteria and divided into 2 groups with 15 patients in each group by computerized random technique. Group A was treated with Apamarga Pratisaraniya Kshara, while Group B was treated with Shireesha Beejadi Lepa. Results: It was found that the main clinical features like Pain were reduced 84.09% in Group A and 90.90% in Group B, Bleeding per Rectum were 68.18% in Group A and 86.36% in Group B. Colour of Pile mass changes of 75% in Group A and 81.81% in Group B. Size of Pilemass reduced 70.45% in Group A and 68.18% in group B after 7th day of treatment. Conclusion: Apamarga Pratisaraniya Kshara had significant result over Shireesha Beejadi Lepa Yoga in both subjective and objective parameters with P value less than 0.0001

2020 ◽  
Vol 21 (2) ◽  
pp. 105-110
Author(s):  
Md Shawkat Alam ◽  
Sudip Das Gupta ◽  
Hadi Zia Uddin Ahmed ◽  
Md Saruar Alam ◽  
Sharif Muhammod Wasimuddin

Objective: To compare the clean intermittent self-catheterization (CISC) with continuous indwelling catheterization (CIDC) in relieving acute urinary retention (AUR) due to benign enlargement of prostate (BEP). Materials and Methods :A total 60 patients attending in urology department of Dhaka Medical college hospital were included according to inclusion criteria ,Patients were randomized by lottery into two groups namely group –A and group –B for CISC and IDC drainage respectively . Thus total 60 patients 30 in each group completed study. Results : Most men can safely be managed as out-patients after AUR due to BPH. The degree of mucosal congestion and inflammation within the bladder was found to be lower in those using CISC and the bladder capacity in these patients was also found higher.Patients with an IDC had a high incidence of UTIs then that of patients with CISC. During the period of catheterization the incidence of UTI was 43.3% in group B in comparison to 40% in group A; before TURP 36% in group B in comparison to 10% incidence in group A.According to patient’s opinion CISC is better than IDC in the management of AUR. Experiencing bladder spasm, reporting blood in urine, management difficulties, incidence and severity of pain were less in CISC group, and the method of CISC was well accepted by patients as well as their family members. Conclusion: From the current study it may be suggested that CISC is better technique for management of AUR patient due to BPH than IDC. It can also be very helpful when surgery must be delayed or avoided due to any reasons in this group of patients. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p.105-110


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
N A Fahmy ◽  
S M Alfawal ◽  
H S Abdelsamie ◽  
A M Hassan

Abstract Background Atrial fibrillation (AF) is the most common sustained arrhythmia affecting humans. It is an electrical disturbance that leads to rapid, disorganized, and asynchronous contraction of the atrial muscle. In clinical practice, it accounts for approximately one-third of hospitalizations for cardiac rhythm disturbances. The incidence of AF increases from less than 0.1% per year in those under 40 years old to exceed 1.5% per year in women and 2% per year in men older than 80 years. Aim of the Work: to discuss the effect of variation in amiodarone use (including dosage and duration) on dysrhythmia recurrence in patients with new-onset AF in ICU. Patients and Methods This was a prospective observational study conducted over 6 months, 60 patients who fulfilled inclusion criteria were included in the study divided in two groups according to amiodarone dosage, each group is 30 patients: Group (A): received a loading dose of amiodarone followed by an infusion (1200mg amiodarone). Group (B): received a loading dose of amiodarone not followed by an infusion (300mg amiodarone). Results a significant positive correlation was observed between level of C-reactive protein (CRP) and the rate of AF recurrence. As regard effect of CRP on AF recurrence; in AF recurrent patients, mean is (191±77.3) with range from 15 to 352 which significantly differed from Non-recurrent AF patients, mean is (89±63) with range from 20 to 223 (p value <0.001). AF recurrence was higher in group (B) than group (A),. In group (A) 8 patients had recurrent AF representing 26.7 % and in group (B) 19 patients had AF recurrence representing 63.3% (p value =0.004). Conclusion Patients with new-onset AF in (ICU) who are treated with amiodarone should receive a loading dose, immediately followed by an infusion.


Author(s):  
Shivpal Moond ◽  
K.P. Banerjee ◽  
Rakhi Arya

Objective: To compare efficacy, safety and tolerance of combination of Mifepristone and Misoprostol versus Misoprostol alone in induction of labour in late intrauterine fetal death (>24 weeks). Methods: This prospectively study included 160 women with late intrauterine fetal death (IUFD) after 24 weeks of gestation and divided the women randomly into two groups each containing 80 women. In Group-A : Mifepristone 200 mg single dose was given and after 24 hrs Tab Misoprostol (intravaginally) administered and repeated 4 hourly upto a maximum of 5 doses, while in Group-B : Only Tab Misoprostol administered intravaginally 4 hourly upto maximum 5 doses. Induction-delivery interval and number of doses of Misoprostol was calculated.    Results: The mean induction-delivery interval in Group-A was 13.02 ± 3.74 hours and in Group-B was 16.09 ± 2.99 hours (p-value <0.0001). Mean doses of Misoprostol required in Group-A was 3.36 ± 1.08 hours and in Group-B was 4.32 ± 0.65 hours (p-value <0.0001). Conclusion: Combination of Mifepristone and Misoprostol is more effective as comparison to Misoprostol in terms of induction-delivery interval and number of doses of misoprostol required.    Keywords: IUFD, mifepristone, misoprostol, induction of labour, induction-delivery interval.


2015 ◽  
Vol 2 (1) ◽  
pp. 22-26
Author(s):  
Bilal Khattak ◽  
Faiz -Ur- Rahman ◽  
Irfan -Ul-Islam Nasir ◽  
Muhammad Iftikhar ◽  
Imtiaz Ahmad Khattak ◽  
...  

Objective:To evaluate the safety regarding anastomotic failure of single layer interrupted extra mucosal intestinal anastomosis in comparison with double layer intestinal anastomosisMethodology:This prospective comparative study was conducted in surgical A unit of Lady reading Hospital Peshawar from 1st June 2007 to 1st February 2008 (8 months).Patients were divided into two groups, each comprising 60 patients. First 60 consecutive patients were included in Group A, for single layer extra mucosal anastomosis while Group B included last 60 consecutive patients for double layer inverting anastomosis (continuous inner and interrupted outer Lambert sutures). All the cases were admitted through OPD and emergency. The safety of two techniques of anastomosis was analyzed by comparing the outcome in terms of complications.Results:In this study, anastomosis leakage occurred only in 4 (3.33%) patients, one (1.67%) in group A and three (5%) in group B with a P-Value 0.138. Mean age of patient in group A was 36.15 years (+/- 6.0 years) and in group B was 33.25 years (+/- 5.5 years).Conclusion:Single layer extra-mucosal anastomosis has least anastomotic leakage and other complication like wound infection, septicemia, and collection and burst abdomen than in patients with double layer investing anastomosis.


2021 ◽  
Vol 17 (3) ◽  
pp. 222-226
Author(s):  
Anum Malik ◽  
Arshad Shahani ◽  
Jawad Zahir ◽  
Hassam Zulfiqar ◽  
Tabassum Aziz

Objective: To compare the efficacy of dexamethasone 8mg versus ondansetron 4mg in preventing postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy Methodology: This quasi-experimental study was conducted at the Department of Anaesthesia and Intensive Care, Holy Family Hospital from 29th July 2018 to 28th January 2019.  Anesthesia was induced with propofol (2mg/kg IV) and Atracurium (0.5 mg/kg IV) was given to facilitate tracheal intubation. Nalbuphine (0.2mg/kg) was used as analgesic.Patients were randomly divided into two groups. Patients in Group A received 4mg ondansetron at end of surgery and Group B received 8mg dexamethasone at induction. Results: A total of 90 patients were included according to the inclusion criteria of the study. The mean age (years) in the study was 37.11+10.60 years. Frequency and percentage of nausea (up to 24 hours) among both the groups was 28 (62.2) and 28 (62.2) respectively (p-value = 1.0) while the frequency and percentage of vomiting (within 24 hours after extubation) was 28 (62.2) and 27 (60.0) respectively (p-value = 0.829) Conclusion: The study concluded that there was no significant difference dexamethasone and ondansetron in preventing postoperative nausea and vomiting.


Author(s):  
Anu Gupta ◽  
Kalpana Patni

Background: Amavata is the most common form of inflammatory arthopathy seen in India. Among adult population below the age of 50 years this is the most common form of arthritis. For the present study, on Amavata as shaman therapy, Khanda Shunthi and Prasarni Avleha the Ushnaveeryadravya medicaments were chosen. Aims & Objective: The present research work aimed at to evaluate efficacy and establish safe use of Khanda Shunthi and Prasarni Aavaleha in Amavata. Materials & Methods: 40 subjects of Amavata fulfilling the inclusion criteria were selected from OPD and IPD of Desh Bhagat Ayurvedic Hospital, Mandi Gobindgarh, Punjab and randomly divided into two groups, group A and B, comprising each of 20 patients. Group-A subjects received Khanda Shunthi for 60 days, Group-B subjects received Prasarni Avaleha for 60 days. Assessments were done on 0th and 60th day of treatment. Results and Conclusions: In both the groups, highly significant results were observed in all the cardinal parameters with P value for fever and Hb are greater than 0.05 hence there is no significant difference in effect of Group A and Group B on fever and Hb. P values for all other symptoms are less than 0.05 hence we conclude that there is significant difference in effect of group A and group B on pain, swelling, stiffness, fever, ESR, walking time and grip strength. On comparison group A treatment is more effective than group B for all assessment criteria.


2006 ◽  
Vol 13 (02) ◽  
pp. 175-177
Author(s):  
ANEEL ASLAM ◽  
FAWAD ALAM ◽  
ADEEL ASLAM

A comparative study was conducted in CMH, Malir, CMH, Kharian andWT (Pvt) Ltd. Gynaecology and Obstetrics, Multan from April 2001 to March 2004. The Apgar score of neonate wascompared for thiopentone or propofol in C-section patients. Two groups of patients were made. Group-A was inducedwith thiopentone and group-B was induced with propofol. Each group had 100 patients. In group-A 13 neonatesrequired manipulation and 2 neonates in group-B also required manipulation like mask ventilation or endotrachealintubation and one of drugs like atropine to improve apgar score. 13% neonates in group-A and 1% neonates in group-B required manipulation. This clearly shows the superiority of propofol over thiopentone as an induction agent in Csection.The P value of group-A was 0.13 and for group B was 0.02 and had had a statistically significant difference.


Author(s):  
Renu K. Sinha ◽  
Santoshi Gupta

Background: At term, infection remains the most serious complication associated with PROM for the mother and the neonate Induction of labour significantly reduces the risk of maternal and foetal infection. This randomized comparative study has been done to compare the effectiveness and safety of low and high dosage (25 mcg and 50mcg) regimen of vaginal misoprostol for induction in term PROM patients.Methods: At term, infection remains the most serious complication associated with PROM for the mother and the neonate Induction of labour significantly reduces the risk of maternal and foetal infection. This randomized comparative study has been done to compare the effectiveness and safety of low and high dosage (25 mcg and 50mcg) regimen of vaginal misoprostol for induction in term PROM patients.Results: PROM to delivery interval was significantly shorter with 50mcg vaginal misoprostol as compared to 25 mcg vaginal misoprostol (15.71±3.29 hours vs. 18.23±3.23 hours, (p value = 0.0023) Number of doses required was less with 50mcg vaginal misoprostol group as compared to 25mcg vaginal misoprostol (1.22±0.42 vs. 1.91±0.80, p value <0.05). 83.6% women in group A and 69.09% women in group B underwent spontaneous vaginal delivery within 24 hours. 3.64% women in group A and 7.27% in group B had instrumental delivery. Caesarean section was performed in 12.27% cases in group A and 23.64% cases in group B. The complication rate was comparable.Conclusions: 50mcg vaginal misoprostol is more effective and safe for induction of labour at term PROM as compared to 25 mcg vaginal misoprostol 


2020 ◽  
Vol 27 (05) ◽  
pp. 1038-1042
Author(s):  
M. Rehman Gulzar ◽  
Faiqa Aslam ◽  
Muhammad Umar Farooq ◽  
Shahbaz Ahmad ◽  
Sabeen Adil ◽  
...  

Objectives: To compare the results of linear closure technique with purse string closure technique in terms of surgical site infection, wound healing (scar cosmesis) and wound length. Study Design: Comparative Study. Setting: Surgical Unit V, Faisalabad Medical University, Faisalabad. Period: January 2016 to January 2019. Material & Methods: A total of 100 patients were operated in our unit during the study period & were allocated into two groups randomly: Group A (Linear closure) Group B (Purse string closure) included 50 patients in each group. The primary outcome measures were, surgical site infection, wound healing (scar cosmesis) and wound length. Results: During follow up period Surgical site infection was noted in 17 patients out of 100 with 14 patients in Group A and 03 Patients in Group B (p value 0.002). Regarding wound healing 60% patients were having good scar and 20% patients were having satisfactory and 20% having poor scar in Group A. while in Group B 82% patients were having good scar and 18% patients were having satisfactory scar (p value 0.00). Mean wound length in Group A was 5.14 with SD 1.2978 while in Group B mean length was 3.8 with SD 1.3095. Conclusion: Our study concludes that purse string closure is superior to linear closure technique in terms of surgical site infection, wound healing (scar cosmesis) and wound length.


2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Ahmed Abdelwahed ◽  
Izabela Slezak ◽  
Sarah Witting ◽  
Narayanan Vinod Kumar ◽  
Rudolf Zach ◽  
...  

Abstract Aim To assess whether the new direct pathway (requested by GP) has improved OGD accessibility and time of diagnosis for patients with suspected UGI cancer. The new system aimed to bypass a formal referral to UGI clinic. Methodology Retrospective study, compared two groups of patients (total 329). Group A (173 patients, TWW referral to UGI clinic who had endoscopy between March and May 2017), and Group B (156 patients, Direct access pathway by the GP to have the endoscopy between March and May 2018). inclusion criteria includes patients referred directly by the GP between March and May 2018, TWW patients referred March-May 2017. Patients who had OGD with suspected diagnosis other than UGI cancer were excluded. Data was compared in terms of gender, age, interval time between referral and OGD, and cancer findings. Findings Time between presentation and diagnosis in patients referred via Direct Access pathway was shown to be significantly shorter compared to patients admitted via TWW. The difference was 7 days in favor of the Direct Access pathway which was statistically significant (p value 0.001). Recommendations Direct access pathway has decreased the waiting time, expedited the management, potential money saved, more available clinic space and less administrative work.


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