scholarly journals Thermos Ability in Maintaining Crystalloid Liquid Temperature (Ringer’s Lactate and Normal Saline 0,9%): an Alternative in Maintaining Resuscitation Fluid Temperature

2013 ◽  
Vol 9 (2) ◽  
pp. 187-195
Author(s):  
Ninda Saputri ◽  
◽  
Abdurrahman Wahid ◽  
Tina Handayani Nasution ◽  
Gia Eka Negara
Keyword(s):  
Normal Saline ◽  
Haemorrhagic Shock ◽  
Fluid Temperature ◽  
Ringer Lactate ◽  
Temperature Changes ◽  
Significant Difference ◽  
Resuscitation Fluid ◽  
Ringer’S Lactate ◽  
Infusion Fluid

Haemorrhagic shock should be treated with fluid therapy at 390°C to avoid hypothermia. Storage of infusion fluid in a rice thermos is one method to maintain the temperature of the infusion fluid. This study aimed to determine the effect of using a thermos to maintain a temperature of 390C crystalloid liquid (ringer lactate and normal saline 0,9%) at a room temperature of 250C. This research method uses experimental quantitative (pre-experimental) with a one-shot case study design. Six bottles of Ringer's lactate and six bottles of normal saline 0,9% were warmed to 390C, then stored in a rice thermos at 250C and the temperature changes were measured for 6 hours. A digital thermometer was used to take measurements. The Mann-Whitney test was used to analyze the data. The results show that the temperature of Ringer's lactate fluid was reduced by an average of 4,60C, and normal saline was reduced by an average of 4,30C. There was a significant difference in temperature changes in the ringer's lactate fluid and normal saline 0,9% (p=0,000;α=0,05). The results of the study were that the rice thermos was able to maintain the temperature of ringer's lactate fluid at 390C for 96 minutes and normal saline 0,9% for 78 minutes, while to prevent hypothermia (360C) ringer's lactate fluid for 4 hours 59 minutes and normal saline 0,9 % for 4 hours 55 minutes.

scholarly journals Effectiveness of Thermos to Maintain the Temperature of Ringer Lactate and Normal Saline 0.9% at AC Temperature 18˚C

2013 ◽  
Vol 9 (2) ◽  
pp. 204-211
Author(s):  
Rifda Nur A Arif ◽  
◽  
Abdurrahman Wahid ◽  
Ifa Hafifah ◽  
Gia Eka Negara
Keyword(s):  
Fluid Resuscitation ◽  
Normal Saline ◽  
P Value ◽  
Ringer Lactate ◽  
Temperature Changes ◽  
Significant Difference ◽  
The Media ◽  
Study Type ◽  
Statistical Results

Hemorrhagic shock patients require fluid resuscitation, but extra efforts should be made to provide 39 C fluids to avoid hypothermia. One of the media to maintain temperature is a thermos. The purpose of this research is to identify whether the flasks can keep 39-degree crystalloid fluids at 18 degrees Celsius. This study used a pre-experimental method, with One-Shot Case Study type, 12 bottles of crystalloid liquid was warmed to 39°C, then put into 2 rice flasks, and temperature changes were measured for 6 hours at AC temperature 18˚C. The study was conducted on 30 November 2019. The findings show that temperatures in 6 bottles of RL liquid decreased by 6.8 -7.4 C and in 6 bottles of NS 0.9% liquid decreased by 5.3 - 6.4 C. Statistical results using the Mann-Whitney p-value is 0,000. It was concluded that there was a significant difference between changes in temperature of lactate Ringer's fluid and normal saline 0,9%. A thermos can maintain a temperature of 39˚C for about 1 hour and can prevent hypothermia from reaching 36˚C for about 3 hours.

Side-Effects of Rinsing Fluids on the Rat Femoral Artery

1997 ◽  
Vol 22 (5) ◽  
pp. 568-573 ◽  
Author(s):  
O. DELAERE ◽  
U. MENNEN ◽  
W. VAN HEERDEN ◽  
E. RAUBENHEIMER ◽  
A. M. WIESE ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Side Effects ◽  
Femoral Artery ◽  
Normal Saline ◽  
Vessel Wall ◽  
Experimental Conditions ◽  
Femoral Arteries ◽  
Heparinized Saline ◽  
Significant Difference ◽  
Ringer’S Lactate

Rinsing rat femoral arteries with various fluids in experimental conditions similar to those in clinical practice was found to have deleterious effects on the intimal and medial layers of the vessels. No statistically significant difference was found between the effects of Ringer’s lactate and normal saline. Heparinized saline produced significantly less damage to the medial layer and less platelet cell deposition. Lignocaine 2% was found to be extremely damaging to the whole vessel wall, and highly thrombogenic. Nevertheless, all the arteries in each group remained patent 4 days after rinsing.

scholarly journals Effect of Woolen Cloth to Maintain Temperature 39°C of Crystaloid Fluid Ringer Lactate at Room Temperature 18°C

2021 ◽  
Vol 9 (1) ◽  
pp. 64-71
Author(s):  
Helna Fitriana ◽  
◽  
Abdurrahman Wahid ◽  
Tina Handayani Nasution ◽  
Gia Eka Negara
Keyword(s):  
Room Temperature ◽  
P Value ◽  
Ringer Lactate ◽  
Additional Material ◽  
Temperature Changes ◽  
Crystalloid Fluid ◽  
Significant Difference ◽  
Woolen Cloth ◽  
The Difference ◽  
Wool Cloth

Fluid resuscitation with 39ᵒC is one of the main therapies for hypovolemic (hemorrhagic) shock patients to prevent complications. In this time, we already have tools to keep the fluid warm, but not all health services have these tools. To find out the effectiveness of using woolen cloth against the temperature of Ringer Lactate 39°C crystalloid fluid at room temperature 18°C. This study used a pre-experimental method, with a static group comparison approach, with 4 Ringer Lactate liquid samples divided into 2 groups, namely groups using wool cloth and those not using woolen cloth. Data collected through observation sheets. Data analyzed using the Mann Whitney test. With this p value (0.00001) <α (0.05), it can be concluded that there is a significant difference between the use of woolen cloth and those that do not use woolen cloth. The woolen cloth is effective to slow down the decrease in temperature of the crystalloid liquid Ringer Lactate 39ᵒC at room temperature 18ᵒC. The difference in temperature changes in the Ringer Lactate crystalloid fluid is influenced by several things including humidity, ambient temperature, and additional material used.

scholarly journals Effects of Ringer Lactate Normal Saline Combination Vs Normal Saline during Renal Transplantation Surgery on Early Postoperative Outcome

2019 ◽  
Author(s):  
Pejman Pourfakhr ◽  
Alireza Sohrabi Nodehi ◽  
Hamid Reza Shariefnia ◽  
Mohammad Reza Khajavi
Keyword(s):  
Renal Transplantation ◽  
Normal Saline ◽  
Urine Output ◽  
Postoperative Outcome ◽  
Fluid Replacement ◽  
Kidney Transplant Recipients ◽  
Ringer Lactate ◽  
Serum Chloride ◽  
Significant Difference ◽  
Kidney Transplantations

Background: Traditionally normal saline is the most common crystalloid solution that is used in transplant surgery. Normal saline (NS) because of the higher risk of acidosis and higher levels of serum chloride may have more deleterious effects in kidney transplant recipients Thus; the aim of this study was to determine the safety of ringer lactate normal saline combination if used during a renal transplant. Methods: One Hundred adults undergoing kidney transplantations were enrolled in a double-blinded randomized prospective clinical trial. They were divided into two groups in order to receive RL& NS and NS infusion as intraoperative IV fluid replacement therapy. All patients received 40 ml/kg fluid during surgery. Serum chloride, sodium, Cr and BUN were checked before operation and 6hour after surgery. Urine output BUN and Cr was also checked in 1, 3 and 7 day after surgery. At the end of surgery, we corrected the acid base status with bicarbonate according to base excess< -15 or PH<7.15 if needed in both groups. Results: There was a significant difference in the serum chloride level (p= 0.001) and urine output (p= 0.003) between the two groups at the 6 hours after transplantations. Postoperative BUN and Cr level at 2,3 and 7 days in RL&NS group was significantly lower than group of NS (P= 0.011). Also, urine output during this study time was significantly higher in RL&NS group (p=0.001). Conclusion: Combination of Ringer lactate &normal saline crystalloid solutions are associated with higher urinary output and most favorited out come in the early post-operative days after renal transplantation surgeries.

scholarly journals Comparison of the Effects of Albumin 5% versus Ringer's Lactate on Blood Loss and Coagulation after Vascular Surgery Using Thromboelastography

2019 ◽  
Vol 7 (8) ◽  
pp. 1335-1341
Author(s):  
Ahmed Abdalla Mohamed ◽  
Nadia Gameel Elsharkawi ◽  
Osama Ismail Zaid ◽  
Ahmed Farag Mohamed ◽  
Nashwa Nabeel Mohamed ◽  
...  
Keyword(s):  
Blood Loss ◽  
Vascular Surgery ◽  
Trigger Point ◽  
Demographic Data ◽  
Human Albumin ◽  
Ringer Lactate ◽  
Randomised Study ◽  
Coagulation Profile ◽  
Significant Difference ◽  
Ringer’S Lactate

AIM: Comparing the effects of Albumin 5% versus Ringer's lactate on blood loss and coagulation after vascular surgery using METHODS: In this randomised study, 60 patients, aged (18-60 years) ASA physical status (I-III) undergoing vascular surgery were included in the study and randomly allocated into two groups using a random number generator, to receive either Human albumin or Ringer lactate after obtaining written informed consent. Group A received 1-2 ml per minute of human albumin 5% combined with normal saline (0.9%). Group B received Ringer's lactate only as of the main solution. Variables were measured after administration of fluids as postoperative measures. The amount of blood needed for testing was 4 ml drawn before the operation and at the end of surgery with a citrate tube (blue tube) from the venous line or using a regular needle. The standard time of 15 minutes was considered to begin processing. RESULTS: There was no statistically significant difference observed between both groups regarding demographic data, surgical wound drainage, haemoglobin level, hematocrit level and coagulation profile. Regarding ROTEM thermoelectrometry variables showed that there was no statistically significant difference was found between the two groups In-TEM variables (Ex-TEM Clotting time, TEM Clot Formation Time) but In-TEM Alpha Angel measured in degrees showed a Statistically significant difference between the two groups. P < 0.001 and Ex-TEM Maximum Clotting Firmness MCF values measured in mm, there was a statistically significant difference between the two groups P = 0.045. CONCLUSION: This study concluded that the use of human albumin (5%) in vascular surgeries before reaching the trigger point for blood transfusion didn’t improve blood loss or coagulation profile compared to the use of ringer lactate only. Therefore, ringer lactate can be used as a good replacement for human albumin. Ringer lactate is readily available and inexpensive while human albumin may be costly.

scholarly journals Heat Generation and Temperature Control during Bone Drilling for Orthodontic Mini-Implants: An In Vitro Study

2021 ◽  
Vol 11 (16) ◽  
pp. 7689
Author(s):  
Ibrahim Barrak ◽  
Gábor Braunitzer ◽  
József Piffkó ◽  
Emil Segatto
Keyword(s):  
In Vitro Study ◽  
Vitro Study ◽  
Fluid Temperature ◽  
Drilling Speed ◽  
Temperature Changes ◽  
Irrigation Fluid ◽  
Pilot Hole ◽  
Significant Difference ◽  
The Impact

Background: The purpose of our in vitro study was to evaluate the impact of different irrigation fluid temperatures in combination with different drilling speeds on intraosseous temperature changes during mini-implant site preparation. Methods: Porcine ribs were used as bone specimens. Grouping determinants were as follows: irrigation fluid temperature (10 and 20 °C) and drilling speed (200, 600, 900, and 1200 RPM). The axial load was controlled at 2.0 kg. Temperature measurements were conducted using K-type thermocouples. Results: Extreme increments were observed only in the unirrigated groups. Irrigation invariably made a significant difference within groups defined by the same drilling speed. The comparison of the different temperature irrigation fluids (10 and 20 °C) in combination with the same drilling speed (200, 600, 900, or 1200 rpm) resulted in a statistically significant difference between the two different temperatures, whereas the use of irrigation fluid at a controlled room temperature of 20 °C showed significantly higher temperature changes. Conclusions: Based on the results of the study, we conclude that irrigation while preparing a pilot hole for a self-tapping orthodontic miniscrew is of utmost importance, even at low drilling speeds. The temperature of the cooling fluid does influence local temperature elevation to a significant extent.

scholarly journals Changes of Walking Activity During the First Cycle Phases of COVID-19 Pandemic: A Case Study of Seoul, Korea

2021 ◽  
pp. 193758672110265
Author(s):  
Youngjun Park ◽  
Haekwon Chung ◽  
Sohyun Park
Keyword(s):  
Public Health ◽  
Physical Inactivity ◽  
Voluntary Participation ◽  
Walking Activity ◽  
Significant Difference ◽  
Before And After ◽  
Acceleration And Deceleration ◽  
Preliminary Study ◽  
The Government

Aim: This study explores the changes in regular walking activities during the phases of the pandemic. Background: With the spread of COVID-19 transmission, people are refraining from going out, reducing their physical activity. In South Korea, COVID-19 broke out in the 4th week of 2020 and experienced the first cycle phases of the pandemic, such as outbreak, widespread, and decline. In response to the pandemic, the government encouraged voluntary participation in social distancing campaigns, and people reduced their outside activities. Methods: This article examines the decrease and increase of the Prevalence of Regular Walking (≥30 min of moderate walking a day, on ≥5 days a week) by the COVID-19 phases. This study is based on weekly walking data for 15 weeks in 2020, via the smartphone healthcare app, which is managed by 25 public health offices of the Seoul government. Results: According to the findings, the level of prevalence of regular walking (PRW) has a significant difference before and after the outbreak, and every interval of the four-stage COVID-19 phases, that is, pre-pandemic, initiation, acceleration, and deceleration. The level of PRW sharply decreased during initiation and acceleration intervals. In the deceleration interval of COVID-19, the PRW kept increasing, but it has not yet reached the same level as the previous year when the COVID-19 did not exist. Conclusions: As a preliminary study, this study explains empirically how COVID-19 changed PRW in Seoul. It would be helpful to enhance our understanding of the changes in physical inactivity in the pandemic period.

scholarly journals Outcome of the use of 0.9% saline versus 0.45% saline for fluid rehydration in moderate and severe diabetic ketoacidosis in children

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Nora El Said Badawi ◽  
Mona Hafez ◽  
Heba Sharaf Eldin ◽  
Hend Mehawed Abdelatif ◽  
Shimaa Atef ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Diabetic Ketoacidosis ◽  
Normal Saline ◽  
Sodium Concentration ◽  
Saline Group ◽  
Serum Electrolytes ◽  
Serum Chloride ◽  
Significant Difference ◽  
Rehydration Solution ◽  
The Moment

Abstract Background The debate for the optimum sodium concentration in the rehydration solution in diabetic ketoacidosis (DKA) persists till the moment. The aim was to compare the outcome of 0.9% saline versus 0.45% saline in children with moderate and severe (DKA) regarding the effect on serum electrolytes, duration of DKA resolution and the incidence of hyperchloremia. Results A retrospective analysis of 121 children with moderate or severe DKA was done. After the initial 4 h in which both groups received normal saline, patients were divided into two groups continuing on 0.9% (N=72) or switched to 0.45% saline (N=49). Serum chloride and Cl/Na ratios were significantly higher in 0.9% saline group at 4 and 8 h. The 0.9% saline group had significantly higher proportion of hyperchloremia at 4 and 8 h (P value: 0.002, 0.02). The median duration of correction of DKA (14 h among 0.9% saline versus 10 h among 0.45% saline) without significant difference (P value= 0.43). The change in plasma glucose, effective osmolarity, corrected Na levels were comparable between groups. Conclusion There is an unavoidable iatrogenically induced rise in serum chloride with higher incidence of hyperchloremia with the use of normal saline in rehydration of children presenting in DKA and shock. The use of 0.45% saline as post-bolus rehydration fluid is not associated with a decline in the corrected serum sodium concentration and does not affect the rate of correction of acidosis or rate of drop in blood glucose or duration of DKA resolution when compared to normal saline.

scholarly journals Artificial life and ‘nature’s purposes’: The question of behavioral autonomy

Human Affairs ◽  
2020 ◽  
Vol 30 (4) ◽  
pp. 587-596
Author(s):  
Elena Popa
Keyword(s):  
Artificial Life ◽  
Life Forms ◽  
Behavioral Traits ◽  
Ethical Implications ◽  
Autonomous Behavior ◽  
Significant Difference ◽  
Behavioral Autonomy ◽  
Synthetic Life ◽  
Biological Organisms

AbstractThis paper investigates the concept of behavioral autonomy in Artificial Life by drawing a parallel to the use of teleological notions in the study of biological life. Contrary to one of the leading assumptions in Artificial Life research, I argue that there is a significant difference in how autonomous behavior is understood in artificial and biological life forms: the former is underlain by human goals in a way that the latter is not. While behavioral traits can be explained in relation to evolutionary history in biological organisms, in synthetic life forms behavior depends on a design driven by a research agenda, further shaped by broader human goals. This point will be illustrated with a case study on a synthetic life form. Consequently, the putative epistemic benefit of reaching a better understanding of behavioral autonomy in biological organisms by synthesizing artificial life forms is subject to doubt: the autonomy observed in such artificial organisms may be a mere projection of human agency. Further questions arise in relation to the need to spell out the relevant human aims when addressing potential social or ethical implications of synthesizing artificial life forms.

scholarly journals 1241. PfSPZ Vaccine Administered by Direct Venous Inoculation to Prevent Plasmodium falciparum Malaria is as Safe as Normal Saline – a Meta-analysis of 12 Randomized Controlled Clinical Trials

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S639-S640
Author(s):  
L W Preston Church
Keyword(s):  
Plasmodium Falciparum ◽  
Random Effects ◽  
Normal Saline ◽  
Meta Analysis ◽  
Laboratory Data ◽  
Plasmodium Falciparum Malaria ◽  
Sub Saharan Africa ◽  
Sensitivity Analyses ◽  
Double Blind ◽  
Significant Difference

Abstract Background Sanaria’s PfSPZ Vaccine prevents Plasmodium falciparum (Pf) infection transmitted in the field and by controlled human malaria infection. Safety of PfSPZ Vaccine has been demonstrated in 12 randomized, double-blind, placebo-controlled trials (RCT) varying in regimen from 3 to 5 doses over 4 to 20 weeks and in size from 18 to 332 subjects in adults in the US and EU and 5-month to 65-year-olds in 5 countries in sub-Saharan Africa. This study was conducted to analyze solicited adverse event (AE) and laboratory data by random effects meta-analysis. Methods PfSPZ Vaccine is composed of radiation-attenuated, aseptic, purified, cryopreserved Pf sporozoites (SPZ) administered by direct venous inoculation (DVI). Normal saline (NS) is always the placebo. Data from all completed RCTs were included as either age &gt; 18 years (n=598) or age 5 months to 17 years (n=641). Any subject receiving at least one dose was included. A random-effects model was used to study vaccine safety and I2 to evaluate heterogeneity. Analysis was performed for any systemic solicited AE and for the most frequently observed AEs and laboratory abnormalities. Sensitivity analyses were performed by removal of trials with zero events to evaluate potential bias. Results When examined individually, only 1 trial had a significant difference between PfSPZ Vaccine and NS for any AE (myalgias in adults). In the adult meta-analysis, there was no difference in the random effects risk ratios (RR) for having any vaccine-related AEs (1.40, 95% confidence interval (CI) 0.88-2.28), or for fever (0.75, 0.24-2.35), headache (1.23, 0.74-2.02), fatigue (0.72, 0.19-2.54), or myalgia (1.09, 0.26-4.68). In the pediatric meta-analysis there was no difference between the RR for PfSPZ Vaccine and NS for any AE (0.84, 0.59-1.18) or for fever (1.09, 0.44-2.69). No significant differences in the most common grade 2 or higher laboratory abnormalities – declines in hemoglobin, neutrophil or platelet count – were detected. Sensitivity analysis did not change the results. Conclusion There was no difference in risk for AEs or lab abnormalities between PfSPZ Vaccine and NS, indicating that PfSPZ Vaccine administered by DVI was extremely safe and well tolerated in 5-month- to 65-year-olds. Disclosures LW Preston Church, MD, FIDSA, Sanaria Inc. (Employee)

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