scholarly journals COGNITIVE FUNCTIONS CONDITION OF POST-STROKE PATIENTS

Author(s):  
V. R. Gerasymchuk ◽  
I. F. Uwa-Agbonikhena ◽  
L. T. Maksymchuk ◽  
M. Yu. Kupnovytska-Sabadosh ◽  
T. I. Nehrych ◽  
...  

60 patients after a hemispheric ischemic stroke (IS) were examined. Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), Trail Making Test A and B (TMT), and the Clock Drawing Test (CDT) were used for the cognitive status assessment. A decrease in the MMSE, FAB and MoCA score compared to the control group (CG) (p<0.05) was observed, with probable differences mainly in the domains of attention (p<0.05) and executive functions (p<0.05). An increase in the time of task execution by 45.5% was detected for TMT A (p <0.05) and 61.9% for TMT B (p <0.01), and violation of CDT performance compared to the CG (p<0.05). Thus, the study of cognitive status using TMT and CDT may be recommended for timely detection of the initial executive functions impairment.

Author(s):  
V. R. Gerasymchuk ◽  
I. F. Uwa-Agbonikhena ◽  
L. T. Maksymchuk ◽  
M. Yu. Kupnovytska-Sabadosh ◽  
T. I. Nehrych ◽  
...  

60 patients after a hemispheric ischemic stroke (IS) were examined. Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), Trail Making Test A and B (TMT), and the Clock Drawing Test (CDT) were used for the cognitive status assessment. A decrease in the MMSE, FAB and MoCA score compared to the control group (CG) (p<0.05) was observed, with probable differences mainly in the domains of attention (p<0.05) and executive functions (p<0.05). An increase in the time of task execution by 45.5% was detected for TMT A (p <0.05) and 61.9% for TMT B (p <0.01), and violation of CDT performance compared to the CG (p<0.05). Thus, the study of cognitive status using TMT and CDT may be recommended for timely detection of the initial executive functions impairment.


2013 ◽  
Vol 5 (1) ◽  
Author(s):  
Tirzha N. Paparang ◽  
Corry N. Mahama ◽  
Denny J. Ngantung

Abstract: Stroke is a major cause of cognitive dysfunction. The incidences of cognitive dysfunction increase three-fold after strokes, usually involving impairement of abilities in visuo-spacial, memory, orientation, speech, attention, and performance functions. The rapid, practical, and approved examinations used to evaluate and confirm the decline in cognitive functions are the Mini Mental State Examination (MMSE), the Clock Drawing Test (CDT), and the Trail Making Test (TMT). This study aimed to reveal the cognitive functions of outpatients with stroke histories in the Neurology Polyclinic, Prof. Dr. R.D. Kandou Hospital Manado by using the above mentioned examinations. This was a descriptive study with a cross-sectional design conducted in November 2012. The results showed that there were 51 respondents who fulfilled the inclusion criteria consisting of 32 males and 19 females. The highest decline of cognitive function by age, the educational level, and employment was 60-79 years, more than 9 years of education, and retired workers, respectively. The results of the MMSE, CDT, and TMT examinations for cognitive impairment evaluation were as follow: MMSE 62.75%, CDT 56.86%, TMT A 96.08%, and TMT B 84.31%. Conclusion: Most of the outpatients with stroke histories in the Neurology Polyclinic, Prof. Dr. R.D. Kandou Hospital Manado showed cognitive impairments. Keywords: CDT, cognitive function, MMSE, stroke, TMT-A and B.   Abstrak: Stroke merupakan penyebab utama gangguan fungsi kognitif. Insiden gangguan kognitif meningkat tiga kali lipat setelah stroke, dan biasanya melibatkan kemampuan visuospasial, memori, orientasi, bahasa, perhatian dan fungsi eksekutif. Pemeriksaan yang digunakan untuk mengevaluasi dan mengonfirmasi penurunan  fungsi kognitif yang cepat dan praktis namun bernilai tinggi ialah Mini Mental State Examination (MMSE), Clock Drawing Test (CDT), dan Trail Making Test (TMT). Penelitian ini bertujuan untuk mengetahui gambaran fungsi kognitif pada pasien rawat jalan dengan riwayat stroke di Poliklinik Saraf RSUP Prof. Dr. R.D. Kandou Manado. Penelitian ini bersifat deskriptif dengan cross-sectional design dan dilaksanakan selama bulan November 2012. Hasil penelitian memperlihatkan bahwa 51 responden memenuhi kriteria inklusi, terdiri dari 32 laki-laki dan 19 perempuan. Berdasarkan usia, tingkat pendidikan, dan pekerjaan, penurunan fungsi kognitif terbanyak pada usia 60-79 tahun, tingkat pendidikan terakhir >9 tahun, dan pekerjaan pensiunan. Hasil pemeriksaan MMSE, CDT, dan TMT terhadap fungsi kognitif responden ialah: MMSE 62,75%, CDT 56,86%, TMT A 96,08%, dan TMT B 84,31%. Simpulan: Sebagian besar pasien rawat jalan dengan riwayat stroke di Poliklinik Saraf RSUP Prof. Dr. R.D. Kandou Manado telah memperlihatkan gagguan fungsi kognitif.Kata kunci: stroke, fungsi kognitif, MMSE, CDT, TMT-A dan B.


2020 ◽  
Vol 30 (1) ◽  
pp. 43-47
Author(s):  
Alexandru Martis ◽  
Dumitru Zdrenghea ◽  
Gabriel Gusetu ◽  
Gabriel Cismaru ◽  
Bogdan Dutu ◽  
...  

Bradyarrhythmias cause low cerebral blood flow and imbalance of the cerebral autore-gulation, favoring neuronal ischemia and cognitive dysfunction. The main treatment in bradyarrhythmia is pacemaker (PM) implantation, which keeps the heart rate in normal range and increase cardiac output. The present study proposed the cognitive evaluation of PM group patients and a control group (CG), but with similar cardiovascular risk factors. Cognitive assessment has been achieved by applying the Mini-Mental State Examination (MMSE), Clock-Drawing Test (CDT) and Mini Clock for both groups.


e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Reza B. Susanto ◽  
Rizal Tumewah ◽  
Arthur H. P. Mawuntu

Abstract: Indonesia has the highest growth of elderly population. Health problem that often occurs in the elderly is impaired cognitive function which can be examined by using various examinations. Rapid examinations with practical high values are Mini Mental State Examination (MMSE), Clock Drawing Test (CDT), as well as Trail Making Test A and B (TMT A and B). These are done by giving a series of commands to a person and then his/her accuracy will be assessed. This was a cross-sectional study conducted from December 2014 to January 2015 at the Agape elderly nursing home Tondano. The results showed that there were 12 respondents that met the inclusion criteria consisted of eight females and four males. The results of the four tests showed that MMSE had 67% of respondents with normal cognitive function, CDT had 75% with normal executive function, TMT A had 100% with experienced executive interference, and TMT B had 92% with experienced executive interference. Conclusion: Most respondents showed MMSE with normal cognitive function and CDT with, normal executive function, however, all respondents showed TMT A with experienced executive interference, and nearly all respondents showed TMT B with experienced executive interference. Cognitive dysfunction were more frequent among the elderly of ≥75 years, female, primary school education, and unemployment.Keywords: elderly, cognitive function, executive functionAbstrak: Indonesia merupakan negara tertinggi dalam pertumbuhan penduduk lanjut usia. Peningkatan jumlah penduduk lanjut usia tersebut menimbulkan masalah kesehatan, masalah kesehatan yang sering terjadi pada usia lanjut antara lain gangguan fungsi kognitif. Gangguan fungsi kognitif ini dapat di periksa dengan berbagai pemeriksaan. Pemeriksaan yang cepat dan praktis namun nilainya tinggi adalah pemeriksaan Mini Mental State Examination (MMSE), Clock Drawing Test (CDT), Trail Making Test A dan B (TMT A dan B). Pemeriksaan ini dilakukan dengan memberi serangkaian perintah pada seseorang dan ketepatannya dinilai. Penelitian ini menggunakan desain potong lintang, dilakukan pada bulan Desember 2014 hingga Januari 2015 bertempat di Panti Werdha Agape Tondano. Hasil penelitian mendapatkan 12 responden yang memenuhi kriteria penelitian, terdiri dari 8 perempuan dan 4 laki-laki. Hasil pemeriksaan MMSE menunjukkan 67% responden dengan fungsi kognitif normal, CDT menunjukkan 75% dengan fungsi eksekutif normal, TMT A menunjukkan 100% dengan gangguan eksekutif, dan TMT B menunjukkan 92% mengalami gangguan eksekutif. Simpulan: Sebagian besar responden menunjukkan hasil pemeriksaan MMSE dengan fungsi kognitifnya normal, CDT dengan fungsi eksekutif normal, sedangkan untuk TMT A seluruh responden mengalami gangguan eksekutif, dan TMT B hampir seluruh responden mengalami gangguan eksekutif. Secara keseluruhan, gangguan fungsi kognitif lebih banyak pada lansia perempuan usia ≥ 75 tahun, pendidikan SD, dan tidak bekerja.Kata kunci: lansia, fungsi kognitif, fungsi eksekutif


Geriatrics ◽  
2020 ◽  
Vol 5 (2) ◽  
pp. 29
Author(s):  
Miyuki Nemoto ◽  
Hiroyuki Sasai ◽  
Noriko Yabushita ◽  
Keito Tsuchiya ◽  
Kazushi Hotta ◽  
...  

We aimed to develop a novel exercise to improve visuospatial ability and evaluate its feasibility and effectiveness in older adults with frailty. A non-randomized preliminary trial was conducted between June 2014 and March 2015. We recruited 35 adults with frailty (24 women), aged 66–92 years. Participants were assigned to either locomotive- or visuospatial-exercise groups. All participants exercised under the supervision of physiotherapists for 90 min/week for 12 weeks. The visuospatial exercise participants used cubes with six colored patterns and were instructed to “reproduce the same colored pattern as shown in the photo”, using the cubes. In the locomotive exercise group, lower extremity functional training was provided. Rates of retention and attendance measured feasibility. Most participants completed the intervention (77.3%, locomotive; 84.6%, visuospatial) and had good attendance (83.8%, locomotive; 90.7%, visuospatial). Mini-mental state examination (MMSE), clock drawing test (CDT), and seven physical performance tests were conducted before and after interventions. The improvement in the MMSE score, qualitative analysis of CDT, grip strength, and sit and reach assessments were significantly greater in the visuospatial exercise group than in the locomotive exercise group. The cube exercise might be a feasible exercise program to potentially improve visuospatial ability and global cognition in older adults with frailty.


2019 ◽  
Vol 77 (5) ◽  
pp. 330-334 ◽  
Author(s):  
Luis Felipe Scarabelot ◽  
Mariane de Moraes Monteiro ◽  
Mauren Carneiro da Silva Rubert ◽  
Viviane de Hiroki Flumignan Zetola

ABSTRACT Mini-Mental State Examination (MMSE) results are strongly influenced by educational level. The Brief Cognitive Screening Battery (BCSB) is an alternative assessment tool that provides more accurate results in individuals with less education. Objective: Our aim was to compare the MMSE and BCSB as screening tests. Methods: The MMSE and BCSB were assessed in 112 participants by two evaluators blind to the other test's result. Participants were classified according to their level of education. The influence of education level was analyzed using the Kruskal-Wallis and multiple comparison tests. Results: Scores of the MMSE (p < 0.0001) and the clock-drawing test (p < 0.0001) were influenced by education level but the delayed recall test score was not (p = 0.0804). The verbal fluency test (p = 0.00035) was influenced only by higher educational levels. It took three minutes less to apply the MMSE than to apply the BCSB (p < 0.0001). Conclusions: These findings suggest that the delayed recall test and the verbal fluency test of the BCSB are better than the MMSE and clock-drawing test as tools for evaluating cognition in people with limited education.


2015 ◽  
Vol 9 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Mirela Ward ◽  
Juliana F. Cecato ◽  
Ivan Aprahamian ◽  
José Eduardo Martinelli

OBJECTIVE: To evaluate apraxia in healthy elderly and in patients diagnosed with Alzheimer's disease (AD) and Mild cognitive impairment (MCI). METHODS: We evaluated 136 subjects with an average age of 75.74 years (minimum 60 years old, maximum 92 years old) and average schooling of 9 years (minimum of 7 and a maximum of 12 years), using the Mini-Mental State examination (MMSE), Cambridge Cognitive Examination (CAMCOG) and the Clock Drawing Test. For the analysis of the presence of apraxia, eight subitems from the CAMCOG were selected: the drawings of the pentagon, spiral, house, clock; and the tasks of putting a piece of paper in an envelope; the correct one hand waiving "Goodbye" movements; paper cutting using scissors; and brushing teeth. RESULTS: Elder controls had an average score of 11.51, compared to MCI (11.13), and AD patients, whose average apraxia test scores were the lowest (10.23). Apraxia scores proved able to differentiate the three groups studied (p=0.001). In addition, a negative correlation was observed between apraxia and MMSE scores. CONCLUSION: We conclude that testing for the presence of apraxia is important in the evaluation of patients with cognitive impairments and may help to differentiate elderly controls, MCI and AD.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Nunzia Giordano ◽  
Valérie Tikhonoff ◽  
Paolo Palatini ◽  
Anna Bascelli ◽  
Giovanni Boschetti ◽  
...  

In 288 men and women from general population in a cross-sectional survey, all neuropsychological tests were negatively associated with age; memory and executive function were also positively related with education. The hypertensives (HT) were less efficient than the normotensives (NT) in the test of memory with interference at 10 sec (MI-10) (−33%,P=0.03), clock drawing test (CLOX) (−28%,P<0.01), and mini-mental state examination (MMSE) (−6%,P=0.02). Lower MMSE, MI-10, and CLOX were predicted by higher systolic (odds ratio, OR, 0.97,P=0.02; OR 0.98,P<0.005; OR 0.95,P<0.001) and higher pulse blood pressure (BP) (OR 0.97,P=0.02; OR 0.97,P<0.01; and 0.95,P<0.0001). The cognitive reserve index (CRI) was 6% lower in the HT (P=0.03) and was predicted by higher pulse BP (OR 0.82,P<0.001). The BP vectors of lower MMSE, MI-10, and CLOX were directed towards higher values of systolic and diastolic BP, that of low CRI towards higher systolic and lower diastolic. The label of hypertension and higher values of systolic or pulse BP are associated to worse memory and executive functions. Higher diastolic BP, although insufficient to impair cognition, strengthens this association. CRI is predicted by higher systolic BP associated to lower diastolic BP.


2013 ◽  
Vol 71 (10) ◽  
pp. 763-768 ◽  
Author(s):  
Jonas Jardim de Paula ◽  
Debora Marques de Miranda ◽  
Edgar Nunes de Moraes ◽  
Leandro Fernandes Malloy-Diniz

The Clock Drawing Test (CDT) is a cognitive screening tool used in clinical and research settings. Despite its role on the assessment of global cognitive functioning, the specific cognitive components required for test performance are still unclear. We aim to assess the role of executive functioning, global cognitive status, visuospatial abilities, and semantic knowledge on Shulman’s CDT performance. Fifty-three mild cognitive impairment, 60 Alzheimer’s dementia, and 57 normal elderly controls performed the CDT, the Frontal Assessment Battery, the Mini-Mental State Examination, the Stick Design Test, and a naming test (TN-LIN). An ordinal regression assessed specific neuropsychological influences on CDT performance. All the cognitive variables were related to the CDT, accounting for 53% of variance. The strongest association was between the CDT and executive functions, followed by global cognitive status, visuospatial processing, and semantic knowledge. Our result confirms the multidimensional nature of the test and the major role of executive functions on performance.


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