Functional analysis of chondroitin 4 sulfate constituting osseointegration

Impact ◽  
2019 ◽  
Vol 2019 (8) ◽  
pp. 18-20
Author(s):  
Shuhei Tsuchiya
Keyword(s):  
Functional Analysis ◽  
Extracellular Matrix ◽  
Dental Implants ◽  
Maxillofacial Surgery ◽  
The Body ◽  
Oral And Maxillofacial Surgery ◽  
Direct Connection ◽  
Tooth Replacement ◽  
Living Bone ◽  
Natural Tooth

Osseointegration can be defined as a direct connection, both structural and functional, between living bone and the surface of an artificial implant. Indeed, the word comes from the Greek term for 'bone' and 'to make whole'. In dentistry, once dental implants are placed, the body will react with osseointegration, enabling the implants to become a permanent part of the jaw. There are many benefits to this type of implant, compared with traditional tooth replacement options, not least that dental implants mimic the strength and functionality of a natural tooth. Dr Shuhei Tsuchiya is a researcher based in the Division of Oral and Maxillofacial Surgery at Nagoya University, Japan, who is interested in a range of areas, including regenerative medicine and the extracellular matrix. One of his key preoccupations, though, is shedding light on osseointegration. He and his team are working to unravel the mysteries of the mechanism.

Main Approaches to the Use of Biomaterials in Oral and Maxillofacial Surgery: A Brief Systematic Review

2021 ◽  
pp. 42-48
Author(s):  
Henrique Esteves Magalhães ◽  
Priscilla Janaína de Lima Borelli Bovo ◽  
Luciano Rodrigues Neves ◽  
Marcelo Henrique Batista Santos ◽  
Rogério Luiz de Araújo Vian ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Tissue ◽  
Dental Implants ◽  
Bone Growth ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Success Rates ◽  
Dental Implantation ◽  
Regeneration Of Bone Tissue ◽  
Regeneration Of Bone

Introduction: In recent years, procedures with the use of dental implants have increased worldwide, reaching approximately one million dental implants per year. In recent years, a platelet concentrate called FRP (fibrin-rich plasma) has been the subject of clinical studies. Associated with this, the biomaterial Bio-Oss® (Geistlich), as it is biodegradable, biocompatible, non-toxic, and has low immunogenicity, and bio stimulators can act in the regeneration of bone tissue, as it establishes with the cells the appropriate biological niche (favorable microenvironment) for bone growth. Objective: Therefore, the present study aimed to evaluate, through a brief systematic review, the results that involve bone formation for dental implantation, with the use of biomaterials such as fibrin-rich plasma and Bio-Oss®. Methods: The model used for the review was PRISMA. Was used databases such as Scopus, Scielo, Lilacs, Google Scholar, PubMed. Results: Fibrin-rich plasma (FRP) as an autologous biomaterial for use in oral and maxillofacial surgery presents most leukocytes, platelets, and growth factors, forming a fibrin matrix, with three-dimensional architecture. The Bio-Oss® biomaterial (Geistlich), as it is biodegradable, biocompatible, non-toxic, and has low immunogenicity and bio stimulators can act in the regeneration of bone tissue, since it establishes with the adenomatous mesenchymal stem cells the appropriate biological niche for bone growth and, thus, allowing the dental implant to be as effective as possible. Conclusion: The use of FRP associated with Bio-Oss® seems to illustrate high success rates with minimal costs, which may reduce the amount of bone graft needed to fill the sinus cavity, reducing the costs of the procedure.

scholarly journals 1359 Everyone Deserves to Smile: An Audit on The Success Rate of Dental Implants in Complex Maxillofacial Patients

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
P Lugaric ◽  
C Frezzini ◽  
A Patterson
Keyword(s):  
Dental Implants ◽  
Maxillofacial Surgery ◽  
Survival Rates ◽  
Oral And Maxillofacial Surgery ◽  
Head And Neck Reconstruction ◽  
Success Rates ◽  
Native Bone ◽  
Local Standard ◽  
Edentulous Patients ◽  
Surgery Department

Abstract Aim To determine the success rates of dental implants in complex patients treated in the Oral and Maxillofacial Surgery Department at Rotherham General Hospital (RGH). Method All patients who received dental implants in the period January 2010 – March 2017 at RGH were included in the audit. Standards 90% local standard Results 68 dental implants were placed in 22 patients: 15 patients head and neck reconstruction, 5 atrophic edentulous patients, 2 trauma. Conclusions Survival rates for dental implants in the literature is variable ranging from 91 -96% in native bone and mucosa and 46 - 98% in irradiated tissue.

scholarly journals Dental Implant Placement with Simultaneous Anterior Maxillary Reconstruction with Block and Particulate Fresh Frozen Allograft Bone: A Case Report with 24-Month Follow-Up Data

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
J. S. Vieira ◽  
E. M. Brandão-Filho ◽  
F. R. Deliberador ◽  
J. C. Zielak ◽  
A. F. Giovanini ◽  
...  
Keyword(s):  
Case Report ◽  
Dental Implants ◽  
Clinical Success ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Allograft Bone ◽  
Anterior Maxilla ◽  
Implant Placement ◽  
Fresh Frozen ◽  
Fixed Prosthesis

Fresh frozen allograft bone is routinely used in orthopedic surgery for the reconstruction of large bone defects, and its use in oral and maxillofacial surgery is increasing. The purpose of this case was to demonstrate the installation of dental implants and the use of fresh frozen bone for reconstruction of anterior maxilla in the same surgery. This case report presents the insertion of dental implants followed immediately by a placement of fresh frozen allograft in block and particle for a reconstruction of atrophic anterior maxillary in the same surgery. Ten months subsequent to this procedure, provisional fixed prosthesis was installed on the implants. Four months later (postoperative month 14), the final fixed prosthesis was installed and the clinical success was observed. The insertion of dental implants followed immediately by a placement of fresh frozen allograft is a safe and efficient process that results in the successful return of dental function and aesthetic rehabilitation for the patient.

scholarly journals Local Hemostatic Measures in Oral and Maxillofacial Surgery

2019 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Platelet Aggregation ◽  
Continuous Process ◽  
Maxillofacial Surgery ◽  
Blood Gases ◽  
The Body ◽  
Oral And Maxillofacial Surgery ◽  
Hormone Signaling ◽  
Signaling System ◽  
Metabolic Products ◽  
Internal Body

Homeostasis is continuous process by which internal body system monitor and maintain constant internal environment. Blood is a connective tissue in fluid state closely connected to all tissues of the body. It has many roles including transport of nutrients, metabolic products, blood gases, thermal regulation hormone signaling system, heat conduction, immune response. Hemostasis is homeostasis of intravascular blood volume and is an important function of blood. It involves four major steps: vasoconstriction, platelet aggregation, coagulation and fibrinolysis [1]. The phase of vasoconstriction reduces the blood flow in preparation for platelet aggregation phase. However, the larger the size of the injured blood vessel the less possibility of vasoconstriction especially with high pressure.

scholarly journals The Role of Chemical Agents in the Microbial Flora with Major Risk of Interventios in Maxilo-facial Surgery

2019 ◽  
Vol 70 (6) ◽  
pp. 1988-1991
Author(s):  
Carmen Gabriela Stelea ◽  
Iulian Constantin ◽  
Cristian Budacu ◽  
Alexandra Lorina Platon ◽  
Mihail Balan ◽  
...  
Keyword(s):  
Oral Surgery ◽  
Maxillofacial Surgery ◽  
The Body ◽  
Small Scale ◽  
Oral And Maxillofacial Surgery ◽  
Periodontal Surgery ◽  
Facial Surgery ◽  
Chemical Agents ◽  
Infectious Etiology

The pathology of the oro-maxilo-facial territory comprises a vast chapter of diseases with primary or secondary infectious etiology, the mouth being the natural cavity of the organism with the most varied and variable flora of bacterial contamination. By the continuity solutions created by the mechanical act of mastication, decubitus of defective prosthetic works, local dento-periodontal infectious processes, but especially of dental or small-scale interventions, open gates and possibilities of penetration into the blood circulation of the microorganisms, which cause the transient bacteria. The study included 243 randomly selected patients, with the address of the Oral and Maxillofacial Surgery Clinic in the period 2016-2018. The inoculation of microorganisms in the oral cavity in circulating blood as a result of oral surgery or dental care procedures is much more common than in other areas of the body. Aggressive dental maneuvers that create solutions of continuity of oral mucosa, gingiva, periodontal surgery, periodontal surgery techniques can cause bacteria.

Prevalence and pattern of oral and maxillofacial trauma in Chhattisgarh- A retrospective study

2021 ◽  
Vol 7 (3) ◽  
pp. 131-134
Author(s):  
Sushmita Batra ◽  
Surabhi Singhai ◽  
Pramod Krishna B ◽  
Rajdeep Singh ◽  
Sushant Soni
Keyword(s):  
Maxillofacial Surgery ◽  
The Body ◽  
Maxillofacial Trauma ◽  
Treatment Modalities ◽  
Oral And Maxillofacial Surgery ◽  
Mandibular Fractures ◽  
High Morbidity ◽  
Maxillofacial Injuries ◽  
Facial Region ◽  
Clinical Records

Maxillofacial trauma is any physical trauma to the facial region, commonly encountered by maxillofacial surgeons, and is often associated with high morbidity and so constitute quite a significant portion of the workload of the oral and maxillofacial surgeon. Maxillofacial injuries can occur as an isolated injury or may be associated with multiple injuries in other parts of the body. To assess the patterns, etiology, and treatment modalities of maxillofacial trauma in a teaching hospital in central India, over a 12-year period. Patients with maxillofacial trauma were identified using the department database and clinical records. 264 patients were identified with maxillofacial trauma in the department of oral and maxillofacial surgery between January 2006 and December 2018. The study showed that there was a male preponderance in all age groups over female. Of the 264 patients with maxillofacial injuries, 83,33% had isolated lower face (mandibular) fractures, followed by midface fractures (10.60%) and panfacial fractures (6.06%). Road traffic accidents (87.12%) were the most common form of etiology for trauma followed by assaults (10.98%). Most trauma were treated with open reduction internal fixation (89%) than closed reduction (11%). The etiology and pattern of maxillofacial injuries reflect the trauma patterns within the community and can thus provide a guide to help design programs toward prevention and treatment.

scholarly journals Knowledge and Attitude of Patients toward Dental Implants as an Option for Replacement of Missing Teeth

2013 ◽  
Vol 14 (1) ◽  
pp. 115-118 ◽  
Author(s):  
AR Yusuf Ahammed ◽  
Suprakash Boddu ◽  
Amit Thareja ◽  
Raghavendra Kandaswamy ◽  
Nilesh Kumar ◽  
...  
Keyword(s):  
Dental Implants ◽  
Treatment Modality ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Missing Teeth ◽  
Level Of Knowledge ◽  
Test Of Significance ◽  
Knowledge And Attitude ◽  
Student’S T ◽  
Implant Treatment

ABSTRACT Objective The present study was undertaken to access the level of knowledge and attitude of patients toward implant treatment as an option for replacement of missing teeth. Materials and methods An epidemiological study was conducted among 440 subjects who attended the OPD of two Departments (Prosthodontics and Oral and Maxillofacial Surgery). A self-administered structured closed ended questionnaire pretested through a pilot survey was used in the study. The data were analyzed using the SPSS version 15.0. The Student's t-test and ANOVA test were used as test of significance. Results Out of 440 subjects asked about the knowledge and attitude about implants, only 33.3% had heard of implants as a treatment modality and dentists were the main source of information. Very few people had undergone implant surgery. The level of awareness increased with education. The main factor for not having implants was due to its high treatment charges. However, they were interested to know more about the implant treatment modality. Conclusion The survey was conducted in a dental institute and majority of the participants were unaware about dental implants. It also showed that need for providing more information to the patients about this treatment modality. How to cite this article Suprakash B, Ahammed ARY, Thareja A, Kandaswamy R, Kumar N, Bhondwe S. Knowledge and Attitude of Patients toward Dental Implants as an Option for Replacement of Missing Teeth. J Contemp Dent Pract 2013;14(1):115-118.

The Role of Extracellular Fluid on the Electrical and Electromechanical Properties of Bone: A Review

1987 ◽  
Vol 110 ◽  
Author(s):  
Dennis A. Chakkalakal
Keyword(s):  
Extracellular Matrix ◽  
Blood Vessels ◽  
Weight Bearing ◽  
Extracellular Fluid ◽  
The Body ◽  
Solid Matrix ◽  
Long Bones ◽  
Electromechanical Properties ◽  
Living Bone ◽  
Pore Fraction

The cells in living bone – osteocytes, osteoblasts and osteoclasts – are embedded in a porous material consisting of an organic-inorganic composite solid containing a distribution of fixed charges, permeated by ionic fluids flowing through a complex network of channels. In the weight-bearing long bones of the body, the largest of these channels are up to a few hundred microns in diameter and contain blood vessels which are connected to the blood supply in the central canal of the long bones. These channels establish fluid connectivity with the cells (osteocytes) responsible for maintenance of the bone tissue through small canals (canaliculi) with diameters ranging down to a tenth of a micron. Outside the blood vessels, perivascular fluid permeates these channels. The solid matrix is itself porous with a high degree of composite material organization beginning at the macromolecular level. The internal connectivity of the pore fraction of the solid, which is not as extensive as the network of channels, and the connectivity of this pore fraction with the fluid channels may affect physiological functions, through its influence on mechanical, electrical and electromechanical properties of the extracellular matrix. It seems apparent that the structure and physical properties of the extracellular material of bone will largely determine the physicochemical environment of the cells. Thus, a materials characterization of the extracellular matrix of living bone has become an essential part of the efforts to advance our knowledge of bone physiology and pathology. This paper is a review of the present state of knowledge of the electrical and electromechanical properties of this material with emphasis on studies that appear to have the most physiological significance.

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