Study on Clinico-Haematol-Biochemical Alterations in Goats Suffering from Trichostrongylosis in Anand District of Gujarat

2019 ◽  
Vol 15 (02) ◽  
pp. 10-13
Author(s):  
N R Rajpura ◽  
G C Mandali ◽  
Neha Rao ◽  
A C Patel

This cross-sectional study was aimed at determining the effect of trichostrongylosis on clinical, hematological, and biochemical parameters in goats. The study included eight healthy control goats and 48 naturally infected goats from the Anand district of Gujarat. The cases having a history of diarrhea, anorexia, weakness, dullness, loss of weight, and not dewormed were selected. Fecal samples of infected goats were examined by direct smear method for the presence of Trichostrongylus spp. eggs and the infection was confirmed by quantitative evaluation and coproculture of the samples for the identification of larvae. The result indicated that the infected goats have significantly elevated rectal temperature, pulse rate, and respiration rate along with diarrhea, dullness, depression, emaciation, and loss of condition. Moreover, there was a significant decrease in the mean Hb, TEC, PCV, lymphocyes, as well as serum total protein, calcium and phosphorus, and a significant increase in TLC, neutrophils, eosinophils, ALT, AST and ALP in infected goats.

Author(s):  
P. Kalpana ◽  
A. Kavitha

Background: The objective was to study the determinants of anemia among pregnant women. There is a negative effect on the health of the mother and as well as that of the child due to anemia in women with pregnancy. Death rate is more in women who are pregnant and having anemia. The objective of this study was to study the determinants of anemia among pregnant women.Methods: A hospital based cross sectional study was carried out among 40 pregnant women over a period of six months. Demographic data like age, residence, occupation etc was recorded. Obstetric data like gravida, parity, previous LSCS was also recorded. The data was presented as means and student’s t test was applied.Results: The mean age was 23.43±3.4 years. Majority were young between the ages of 19-22 years. Majority belonged to urban residents i.e. 57.5%. 20% of the subjects were found to be illiterate. Majority of the mothers were housewives i.e. 82.5%. Majority were multi-gravida i.e. 60%. Majority had no history of abortions in the past i.e. 75%. Out of total 19 repeat pregnancies, majority i.e. 84.2% had lower segment cesarean section. Majority reported that they had normal menstrual history. The mean hemoglobin level was found out to be 7.94 gm/dl. It was found that the mean hemoglobin level did not differ significantly across age, residence, education, occupation, gravidity, history of abortions, type of delivery but differed significantly by abnormal menstrual cycle.Conclusions: Mean hemoglobin level was more in women with normal menstrual history compared to those women with abnormal menstrual history and this difference was found out to be statistically significant. Hence abnormal menses should be promptly treated, hemoglobin assessed.


2018 ◽  
Vol 29 (3) ◽  
pp. 309-315
Author(s):  
Lisiane Bernardi ◽  
Bárbara Capitanio de Souza ◽  
Nicole Canalli Sonda ◽  
Fernanda Visioli ◽  
Pantelis Varvaki Rados ◽  
...  

Abstract The aim of this study was to investigate salivary levels of TGFβ1 and proliferation/ maturation of epithelial mucosa cells in diabetic and hypertensive patients. Design: in this cross-sectional study, whole stimulated saliva and oral mucosa exfoliative cytology specimens were collected from 39 patients that were healthy (control, n=10) or presented history of arterial hypertension (HAS, n=9), diabetes mellitus (DM, n=10) or both (DM+HAS, n=10). Salivary flow rate (SFR), TGFβ1 level in saliva, AgNORs and the epithelial maturation were evaluated. Non-parametric Kruskal-Wallis test, followed by Dunn’s multiple comparison post-test and the Spearman test correlation analysis were used. SFR showed a significant decreased in DM and DM+HAS (0.47±0.11 and 0.64±0.43 mL/min) when compared to control (1.4±0.38 mL/min). DM+HAS presented the highest value of TGFβ1 concentration (24.72±5.89 pg/mL). It was observed a positive correlation between TGFβ1 and glycaemia (R=0.6371; p<0.001) and a negative correlation between TGFβ1 and saliva (R=-0.6162; p<0.001) and glycaemia and SFR (R=-0.5654; P=0.001). AgNORs number and status of maturation of mucosa cells were similar for all conditions. DM and DM+HAS presented the lowest SFR, which correlated with increased TGFβ1 levels. Despite the higher TGFβ1 secretion it was not observed changes in the morphology or proliferation of epithelial cells when diabetes or hypertension was present.


Cephalalgia ◽  
2021 ◽  
pp. 033310242110386
Author(s):  
Koji Sekiguchi ◽  
Narumi Watanabe ◽  
Naoki Miyazaki ◽  
Kei Ishizuchi ◽  
Chisato Iba ◽  
...  

Background Headache is an adverse event of coronavirus 2019 (COVID-19) vaccination. Whether patients with history of headache suffer more from vaccination-induced headaches is unknown. We aimed to uncover if headache patients develop more headaches after COVID-19 mRNA vaccination than healthy controls. Methods We performed a questionnaire survey for nursing staff in our hospital from April to May 2021. Based on baseline characteristics, we divided the participants into migraine, non-migrainous headache, and healthy control, and examined the occurrence and features of headache after COVID-19 vaccinations. Results We included 171 participants (15.2% migraine and 24.6% non-migrainous headache). Headache incidence after vaccinations was significantly higher in the migraine (69.2%) and non-migrainous headache (71.4%) groups than in the healthy control (37.9%) group. The incidence of headaches was significantly higher after the second dose compared to the first (45.6% vs. 20.5%). Conclusion Migraineurs and non-migrainous headache participants developed more headaches compared to the healthy controls after COVID-19 vaccination.


2021 ◽  
Vol 11 (3) ◽  
pp. 9-13
Author(s):  
Nourollah Ramroodi ◽  
Seyed Mehdi Hashemi ◽  
Mehrdad Ramroudi

Objective: The aim of the present study was to investigate the epidemiological pattern of factors associated with ischemic stroke among patients under 50 years old. Methods: The present cross-sectional study was performed on 197 Stroke patients. Individuals with confirmed ischemic stroke based on of CT scan were included in the study. Demographic information included age, sex, history of smoking, place of residence, season of disease incidence, history of contraceptive use in women, history of hypertension, having high blood pressure at the onset of diabetes, hyperlipidemia, heart disease and patient weight. Finally, the collected data was analyzed using SPSS ver. 22. Results: The mean age of participants was 40.18 years. The mean weight, height, body mass index (BMI) were 79.83, 168.63, and 28.12, respectively. A total of 60.4% of the participants were male and 39.6% were female. Moreover, 66.9% were urban residents, 38.6% had complications in winter, 67% were smokers, and 50% used contraceptives. The history of hypertension, diabetes, hyperlipidemia, and heart disease was seen in 69%, 49.7, 66%, and 73.6% of cases, respectively. Also, 53.8% of patients had high blood pressure upon admission. Conclusion: The present study showed that a history of heart disease and a history of hypertension in the past and nicotine use are very common in people with stroke. Considering the above mentioned epidemiological factors, it is recommended to prioritize the mentioned factors when identifying new cases


2019 ◽  
Author(s):  
Haile Woretaw Alemu ◽  
Anthony Carlson

Abstract Objective Cross-sectional study design were used to assess willingness to pay for spectacles among south Gondar presbyopic population.Results Of the total 322 people participating in the study, only 53.4% (172) were experienced by spectacles users. The median gross monthly income of participants was US$ 75.0 (ranged US$ 7.1 - 321.4) and the mean amount of money willing to pay for a pair of spectacles was US$ 17.9 (ranged US$ 1.1-107.1). Participants who were willing to pay US$ 12.5 for a pair of spectacles from a government optical accounted for 63.0% (95% CI: 57.8-68.3), while those willing to pay the minimum international pair of spectacle price US$ 5.6 were accounted 73.9% (95% CI: 68.9-79.2%) and spectacle from local private optical price US$ 17.8 accounted 46.6% (95% CI: 40.4-52.2). Multivariate logistic regression analysis indicated factors such as age (P=0.049), occupation (0.001), monthly income (0.001) and history of the previous spectacle wear (0.005) to be significantly associated with willingness to pay for a pair of spectacles. Public willingness to pay for a pair of spectacle has to be supported with the accessible provision of spectacles to increase spectacle coverage among presbyopic individuals.


Author(s):  
Nasim Shirgholami ◽  
Fatemeh Abdi ◽  
Mahta Mazaheri ◽  
Razieh Sadat Tabatabaee

Background: Amniocentesis, like other invasive methods, has complications such as abortion, premature rupture - second pregnancy and at 29 weeks of membranes, infection, bleeding, etc. Here, we aimed to study the complications of amniocentesis in pregnant women. Methods: This descriptive cross-sectional study was included 409 women with positive first and second stage screening or required amniocentesis referred to Baghaeipour Clinic in 2017. Data was collected by a pre-prepared questionnaire. Results: The mean age of the patients and gestational age was 33.49 ± 6.51 years and 17.39 ± 1.36  weeks, respectively. 132 patients (32.2%) had a history of abortion. Regarding the frequency of needle passage through the placenta, the results showed that in 369 people (90.2%) the needle did not pass through the placenta and in 40 people (9.8%). The needle has passed through the pair. Regarding the frequency distribution of amniocentesis complications, fetal death in (2.4%), bleeding in (2.2%) and PROM (1.7%) were observed in patients and no case of infection and abortion was observed. In terms of age, gestational age, gestational number, placental location, needle passage, aspirated fluid color, history of abortion and type of delivery, there were no significant differences. Conclusion: In this study the most common complication of amniocentesis was fetal death (2.4%), followed by bleeding and Spotting (2.2%), PROM (1.7%), infection and abortion, respectively.


2017 ◽  
Vol 4 (5) ◽  
pp. 1412
Author(s):  
Vinayak Chauhan ◽  
Kashyap Buch

Background: In order to control any disease basic knowledge about the prevalence and risk factors of the particular disease is required.Methods: In this cross-sectional study, 2600 individuals aged between 25 and 70 years old were recruited. Participants were selected from the general population residing in Bhuj, Gujarat, India via simple random sampling. Demographic data were collected. Urine and blood test were performed, and the glomerular filtration rate was estimated.Results: One hundred and thirty participants (10%) had CKD. The mean age was significantly higher in the CKD group. Hypertension and diabetes mellitus were significantly more prevalent among the participants with CKD than those without CKD (P < 0.001 for both). Proteinuria was significantly associated with CKD, whereas a history of urinary tract infection, a history of nephrolithiasis, smoking, serum uric acid level, lipid profile, and blood glucose level were not.Conclusions: Overall, it seems that CKD is a common health problem in Gujarat, but further studies in other parts of this country is recommended for the better estimation of CKD prevalence. This study shows the importance of screening for CKD.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Jacques Mbaz Musung ◽  
Placide Kambola Kakoma ◽  
Clarence Kaut Mukeng ◽  
Stéphane Lubamba Tshimanga ◽  
Jeef Paul Munkemena Banze ◽  
...  

Background. Hypertension is the leading cause of cardiovascular disease morbidity and mortality worldwide. Its struggle involves knowing its prevalence. Insufficient data on hypertension in adults in Lubumbashi, Democratic Republic of Congo (DRC), prompted the conduct of this study. The objectives were to determine the prevalence of hypertension and to identify the associated factors in adults in Lubumbashi. Methodology. A cross-sectional study was carried out among 6,708 adults from October 15th to November 24th, 2018, in Lubumbashi. Anthropometric data, lifestyle, and medical history were collected. Hypertension was defined when the mean of the last two blood pressure (BP) measurements was greater than or equal for systolic (SBP) at 140 mmHg and for diastolic (DBP) at 90 mmHg or a history of taking antihypertensive medication whatever the value of the BP. Logistic regression was used to identify the relative effects of hypertension risk factors and all statistical tests were declared significant at a p value <0.05. Results. The female participants numbered 4479 (66.8%). The mean age of all participants was 47.9 ± 16.5 years. The mean SBP and DBP were 128.4 ± 25.9 mmHg and 79.1 ± 15.3 mmHg, respectively. The overall prevalence of hypertension was 33.6%. This prevalence was statistically higher in women than in men (34.5% vs. 31.7%; p = 0.024 ). After logistic regression, the risk of hypertension increased with age >50 years (aOR = 5.85 [5.19–6.60]), overweight (aOR = 1.25 [1.11–1.41]), obesity (aOR = 1.25 [1.11–1.41]), central obesity (aOR = 1.37 [1.16–1.61]), diabetes mellitus (aOR = 2.19 [1.63–2.95]), alcohol consumption (aOR = 1.21 [1.05–1.39]), nonconsumption of vegetables (aOR = 1.35 [1.02–1.80]), and history of stroke (aOR = 2.57 [1.88–3.51]). Hypertension was inversely associated with being underweight (aOR = 0.68 [0.53–0.87]). Conclusion. The prevalence of hypertension in the city of Lubumbashi is high as in other cities of the DRC and Africa. This situation requires the implementation of prevention, detection, and treatment programs for hypertension.


BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e032711 ◽  
Author(s):  
Warot Lamyai ◽  
Kitkawee Pono ◽  
Danai Indrakamhaeng ◽  
Apichat Saengsin ◽  
Nartya Songhong ◽  
...  

ObjectiveTo determine factors related to recent methamphetamine-associated psychosis (MAP) among individuals recently using methamphetamine (MA).DesignCross-sectional study carried out between July 2015 and June 2017.SettingFour mental health hospitals and one substance abuse treatment centre in Thailand.ParticipantsIndividuals recruited onto the study included those aged 18 years or over, of both sexes, who reported MA use in the month prior to admission.MeasuresAny recent psychosis was confirmed using the Mini International Neuropsychiatric Interview-Plus psychotic module. The Timeline Follow Back was used to determine days of MA use. The severity of MA dependence was assessed using the Severity of Dependence Scale. Quantitative hair analysis was carried out to confirm recent use of MA and to measure the amount of MA use. We compared several characteristics between those who had recently experienced psychosis and those who had not.ResultsThis study included 120 participants without MAP and 113 participants with MAP. The mean age was 28 years and the mean abstinence was 17 days. The levels of MA concentration in hair were not significantly different between groups (p=0.115). Based on the final logistic regression model, the independent factors associated with MAP (OR and 95% CI) included being male (OR 4.03, 95% CI 1.59 to 10.20), ≥16 days of MA use in the past month (OR 2.35, 95% CI 1.22 to 4.52), MA dependence (OR 9.41, 95% CI 2.01 to 44.00) and hospitalisation history related to substance abuse (OR 3.85, 95% CI 2.03 to 7.28).ConclusionsHealth professionals should closely monitor the development of MAP in MA-dependent men who frequently use MA and have a history of hospitalisation for substance abuse. The measure of MA concentration levels in the hair may add no benefit for the prediction of the development of MAP.


2016 ◽  
Vol 46 (5) ◽  
pp. 199
Author(s):  
Andhika T. Hutapea ◽  
Budi Setiabudiawan ◽  
Myrna Soepriadi ◽  
Diet Sadiah Rustama

Background Cord blood-IgE (CB-IgE) levels have been usedwidely as a specific marker of atopic diseases. In some previousstudies, CB-IgE levels in subjects with and without a family historyof atopic diseases have been controversial.Objective To determine the CB-IgE level in newborns and to iden-tify the association between CB-IgE and family history of atopicdiseases.Methods A cross-sectional study was done to compare the CB-IgElevels in neonates with or without a family history of atopic diseasesin mother, father, or siblings. Subjects of this study were 124 new-borns who consecutively born in Puskesmas Kiaracondong,Bandung, during the period of March 2001 to July 2002. Subjectswere divided into 2 groups based on history of atopic diseases.Measurements of CB-IgE levels were done by sandwich ELISAmethods. Data were analyzed by c 2 statistics, t test, ANOVA, andDunkan’s test.Results The mean CB-IgE levels in the group with and without afamily history of atopic diseases were 3.2±2.5 IU/ml and 0.5±0.5IU/ml (P<0.001), respectively. The mean CB-IgE levels in maleand female infants with a family history of atopic diseases were3.3±2.7 IU/ml and 3.03±2.2 IU/ml (P>0.05), respectively. Basedon the cut-off point (1.3 IU/ml), CB-IgE levels had significant posi-tive association with a family history of atopic diseases (OR 156,95%CI 29.61;1104.24). CB-IgE levels in neonates with 1, 2, and 3atopic family members were 1.67±0.78 IU/ml, 3.76±2.11 IU/ml, and6.6±2.7 IU/ml, respectively (F=32.603; P<0.001).Conclusion Most newborns with a family history of atopic dis-eases showed high levels of CB-IgE, but there were no correlationwith gender. The probability of having atopic diseases increase inconcord with the number of family with atopic diseases


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