Cervico-Vaginal Multiple Leiomyomas in a Labrador Dog: A Case Report

Author(s):  
Madhuri Hedau ◽  
V. S. Dhoke ◽  
M. V. Joshi

Leiomyomas are common in the canine female reproductive tract and accounts for 2.4% of all canine neoplasms (Hulland, 1978). Primary vaginal tumors are rare. They are usually secondary to either cervical or vulval lesions. In the vagina, leiomyoma usually presents as a solid single nodule mostly, firm consistency, brown color. In bitches, the tumor appears at middle and old age. Preoperative diagnosis of leiomyoma is challenging. Therefore leiomyoma is often diagnosed during postoperative histologic evaluation. Despite this, there are very few reports of them, apart from occasional surgical or clinical articles. The aim of this paper is to report a case of cervico-vaginal multiple leiomyoma in Labrador bitch.

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Amrit Nasta ◽  
Kunal Nandy ◽  
Yogesh Bansod

Introduction. Leiomyomas are common benign tumours of female reproductive tract and are rarely seen in extrauterine location.Case Report. We report an interesting case of a free lying abdominal leiomyoma presenting as a painless abdominal lump in an elderly gentleman.Discussion. Primary abdominal leiomyomas are uncommon and require surgical removal if symptomatic.


Author(s):  
Mai M. Said ◽  
Ramesh K. Nayak ◽  
Randall E. McCoy

Burgos and Wislocki described changes in the mucosa of the guinea pig uterus, cervix and vagina during the estrous cycle investigated by transmission electron microscopy. More recently, Moghissi and Reame reported the effects of progestational agents on the human female reproductive tract. They found drooping and shortening of cilia in norgestrel and norethindrone- treated endometria. To the best of our knowledge, no studies concerning the effects of mestranol and norethindrone given concurrently on the three-dimensional surface features on the uterine mucosa of the guinea pig have been reported. The purpose of this study was to determine the effect of mestranol and norethindrone on surface ultrastructure of guinea pig uterus by SEM.Seventy eight animals were used in this study. They were allocated into two groups. Group 1 (20 animals) was injected intramuscularly 0.1 ml vegetable oil and served as controls.


Author(s):  
R.P. Apkarian ◽  
J.S. Sanfilippo

The synthetic androgen danazol, is an isoxazol derivative of ethisterone. It is utilized in the treatment of endometriosis, fibrocystic breast disease, and has a potential use as a contraceptive. A study was designed to evaluate the ultrastructural changes associated with danazol therapy in a rat model. The preliminary investigation of the distal segment of the rat uterine horn was undertaken as part of a larger study intended to elucidate the effects of danazol on the female reproductive tract.Cross-sections (2-3 mm in length) of the distal segment of the uterine horn from sixteen Sprague-Dawley rats were prepared for SEM. Ten rats in estrus served as controls and six danazol treated rats were noted to have alterations of the estrus cycle i.e. a lag in cycle phase or noncycling patterns. Specimens were fixed in 3% glutaraldehyde in 0.05M phosphate buffer containing CaCl2 at pH 7.0-7.4 and chilled to 4°C. After a brief wash in distilled water, specimens were passed through a graded series of ethanol, critical point dryed in CO2 from absolute ethanol, and coated with 6nm Au. Observations were made with an IS1-40 SEM operated at 15kV.


Author(s):  
Lawrence M. Roth

The female reproductive tract may be the site of a wide variety of benign and malignant tumors, as well as non-neoplastic tumor-like conditions, most of which can be diagnosed by light microscopic examination including special stains and more recently immunoperoxidase techniques. Nevertheless there are situations where ultrastructural examination can contribute substantially to an accurate and specific diagnosis. It is my opinion that electron microscopy can be of greatest benefit and is most cost effective when applied in conjunction with other methodologies. Thus, I have developed an approach which has proved useful for me and may have benefit for others. In cases where it is deemed of potential value, glutaraldehyde-fixed material is obtained at the time of frozen section or otherwise at operation. Coordination with the gynecologic oncologist is required in the latter situation. This material is processed and blocked and is available if a future need arises.


1966 ◽  
Vol 25 (2) ◽  
pp. 406-409 ◽  
Author(s):  
G. A. Schul ◽  
C. W. Foley ◽  
C. D. Heinze ◽  
R. E. Erb ◽  
R. B. Harrington

1990 ◽  
Vol 2 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Anthony Duncan ◽  
Gabor Ungvari ◽  
Robert Russell ◽  
Annalise Seifert

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