scholarly journals Omalizumab Treatment in Chronic Spontaneous Urticaria During Pregnancy: Report of A Case and Review of the Literature

2021 ◽  
Vol 19 (2) ◽  
pp. 114-117
Author(s):  
Andac Salman ◽  
Meryem Aktaş
Keyword(s):  
Pregnant Woman ◽  
Cohort Studies ◽  
Effective Treatment ◽  
Treatment Option ◽  
Congenital Abnormalities ◽  
Chronic Spontaneous Urticaria ◽  
Review Of The Literature ◽  
Effective Treatment Option ◽  
Increased Risk

ABSTRACT Omalizumab is a safe and effective treatment option for chronic spontaneous urticaria (CSU). Although cohort studies in patients with asthma show no increased risk of congenital abnormalities, very little data exist in the literature regarding the use of omalizumab for CSU during pregnancy. Herein, the safe and successful use of omalizumab updosing in a pregnant woman with CSU along with a review of the published literature is presented. Keywords: Chronic spontaneous urticaria, omalizumab, pregnancy, updosing

scholarly journals Abdominal pain and vomiting during pregnancy due to cholesterolosis

2019 ◽  
Vol 12 (3) ◽  
pp. e227826
Author(s):  
Emilie VJ van Limburg Stirum ◽  
Maria G van Pampus ◽  
Jeroen M Jansen ◽  
Erica WM Janszen
Keyword(s):  
Abdominal Pain ◽  
Pregnant Woman ◽  
Effective Treatment ◽  
Treatment Option ◽  
Hospital Admissions ◽  
Gallbladder Disease ◽  
Effective Treatment Option ◽  
Medical Specialists ◽  
Atypical Symptoms ◽  
In Pregnancy

We present a 22-year-old pregnant woman at 15 weeks of gestation, with abdominal pain and vomiting. We demonstrate that diagnosis and treatment of vomiting and abdominal pain in pregnancy can be difficult. Therefore, involvement of other medical specialists is important when common treatments fail. Cholesterolosis can cause symptoms similar to those caused by cholelithiasis. Controversial to gallstones, identification of cholesterolosis by ultrasound is hard. Cholecystectomy is the only effective treatment option for cholesterolosis and can be performed safely during pregnancy. Cholecystectomy in pregnancy should be considered if, despite atypical symptoms, gallbladder disease is suspected and other diagnoses are ruled out. This may reduce recurrent symptoms, hospital admissions, exposure to harmful drugs and obstetric complications.

scholarly journals 5-HT3 Antagonist for Pregnancy Associated Nausea and Vomiting

2021 ◽  
Vol 5 (9) ◽  
pp. RV9-RV11
Author(s):  
Sumit Ghosh ◽  
Nirankar Dev ◽  
David Matthews
Keyword(s):  
Pregnant Women ◽  
Effective Treatment ◽  
Treatment Option ◽  
First Trimester ◽  
Nausea And Vomiting ◽  
Congenital Defects ◽  
Effective Treatment Option ◽  
Health Authorities ◽  
Increased Risk

5-HT3 antagonists appear to be an effective treatment option in the treatment of nausea and vomiting associated with pregnancy. Literature suggests an increased risk of congenital defects in fetuses exposed to ondansetron during pregnancy, especially during first trimester. Health authorities now suggest that this drug should not be used during this period. However, this decision is debatable and whether ondansetron can be used in pregnant women is still controversial.

scholarly journals Improved artificial urinary sphincter outcomes using a transcorporal cuff placement in patients with a “fragile urethra”

2020 ◽  
Vol 14 (12) ◽  
Author(s):  
Elaine J. Redmond ◽  
Keith F. Rourke ◽  
Steven Tong ◽  
Logan Zemp ◽  
Nathan Hoy
Keyword(s):  
Effective Treatment ◽  
Treatment Option ◽  
Artificial Urinary Sphincter ◽  
Secondary Outcome ◽  
Effective Treatment Option ◽  
Erosion Rates ◽  
Increased Risk ◽  
Urinary Sphincter ◽  
Significant Difference ◽  
History Of

Introduction: The artificial urinary sphincter (AUS) is the most effective treatment option for incontinence after prostate cancer treatment. However, patients with a “fragile urethra” (defined as prior radiotherapy, previous failed AUS, or previous urethroplasty) are at increased risk of AUS failure. The aim of this study was to evaluate outcomes using standard and transcorporal cuff placement in this group of patients. Methods: A retrospective review was performed on patients with a fragile urethra who underwent AUS insertion between 2004 and 2017. The primary outcome was the need for AUS revision. Secondary outcome measures included change in pad use, patient satisfaction, continence (≤1 pad/day), improvement (≥50% change in pad use) and cuff erosion rates. Results: Seventy-six patients met the criteria for inclusion, with a mean age of 71.6 years and a mean followup of 37.9 months. A total of 42.1% had prior radiotherapy, 56.6% had a history of failed AUS, and 19.7% had previous urethroplasty. Transcorporal cuff placement was performed in 31.6% (n=24). These patients had lower revision (20.8% vs. 36.5%; p=0.05) and erosion rates (8.3% vs. 17.3%; p=0.09). There was no significant difference in functional outcomes such as continence (66.7% vs. 73.1%; p=0.57), improvement (100% vs. 90.4%;p=0.17), or satisfaction (82.6% vs. 69.4%; p=0.26), nor for 90-day complications (4.2% vs. 9.6%; p=0.41). Conclusions: AUS insertion is an effective treatment option for post-prostatectomy incontinence in the setting of a fragile urethra. Transcorporal cuff placement in this subset of patients may be recommended, as it is associated with lower revision and erosion rates compared to standard cuff placement.

scholarly journals Treatment of direct carotid-cavernous fistulas with flow diversion – does it work?

2018 ◽  
Vol 25 (2) ◽  
pp. 135-138 ◽  
Author(s):  
Zeynep Hüseyinoglu ◽  
Marvin D Oppong ◽  
Andrew S Griffin ◽  
Erik Hauck
Keyword(s):  
Effective Treatment ◽  
Treatment Option ◽  
Adjunctive Therapy ◽  
High Flow ◽  
Flow Diversion ◽  
Review Of The Literature ◽  
Effective Treatment Option ◽  
Post Traumatic ◽  
Carotid Cavernous Fistulas ◽  
Viable Treatment

Direct carotid-cavernous fistulas (CCFs) are high flow lesions that can be challenging to treat. A number of recent reports suggest that flow diversion may be a viable treatment option. We present a case of a post-traumatic CCF successfully treated with flow diversion and provide a review of the literature. Our results suggest that flow diversion is a potentially effective treatment option for CCFs and is most successful when used as an adjunctive therapy.

scholarly journals The Role of Cannabis within an Emerging Perspective on Schizophrenia

Medicines ◽  
2018 ◽  
Vol 5 (3) ◽  
pp. 86 ◽  
Author(s):  
Jegason Diviant ◽  
Jacob Vigil ◽  
Sarah Stith
Keyword(s):  
Effective Treatment ◽  
Treatment Option ◽  
Adjunctive Therapy ◽  
Review Of The Literature ◽  
Effective Treatment Option ◽  
Fresh Start ◽  
Monoamine Receptors ◽  
The Impact ◽  
Prevailing View

Background: Approximately 0.5% of the population is diagnosed with some form of schizophrenia, under the prevailing view that the pathology is best treated using pharmaceutical medications that act on monoamine receptors. Methods: We briefly review evidence on the impact of environmental forces, particularly the effect of autoimmune activity, in the expression of schizophrenic profiles and the role of Cannabis therapy for regulating immunological functioning. Results: A review of the literature shows that phytocannabinoid consumption may be a safe and effective treatment option for schizophrenia as a primary or adjunctive therapy. Conclusions: Emerging research suggests that Cannabis can be used as a treatment for schizophrenia within a broader etiological perspective that focuses on environmental, autoimmune, and neuroinflammatory causes of the disorder, offering a fresh start and newfound hope for those suffering from this debilitating and poorly understood disease.

scholarly journals COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease

2020 ◽  
Vol 4 (18) ◽  
pp. 4278-4281 ◽  
Author(s):  
Zahidee Rodriguez ◽  
Andi L. Shane ◽  
Hans Verkerke ◽  
Christopher Lough ◽  
Matthew G. Zimmerman ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Effective Treatment ◽  
Treatment Option ◽  
Congenital Heart ◽  
Effective Treatment Option ◽  
Immune Systems ◽  
Key Points ◽  
Donor Variability

Key Points COVID-19 convalescent plasma (CP) may be a safe and effective treatment option in SARS-CoV-2 infection refractory to remdesivir. Infants may benefit from CP despite developing immune systems and donor variability emphasizes the need for characterization prior to use.

scholarly journals Gentamicin susceptibility among a sample of multi-drug resistantNeisseria gonorrhoeaeisolates in India

2016 ◽  
pp. AAC.01907-16 ◽  
Author(s):  
Manju Bala ◽  
Vikram Singh ◽  
Aradhana Bhargava ◽  
Monika Kakran ◽  
Naveen Chandra Joshi ◽  
...  
Keyword(s):  
Effective Treatment ◽  
Treatment Outcomes ◽  
Treatment Option ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Dual Therapy ◽  
Clinical Treatment ◽  
Antimicrobial Susceptibility Testing ◽  
Effective Treatment Option

Antimicrobial susceptibility testing of 258N. gonorrhoeaeisolates by Etest determined that 60.1% were MDR while 5% strains had decreased susceptibility to currently recommended extended-spectrum cephalosporins (ESCs). Among these, 84.5% MDR and 76.9% strains having decreased susceptibility to ESCs were susceptible to gentamicin. No MDR isolate was resistant to gentamicin. Thesein vitroresults suggest that gentamicin might be an effective treatment option for the MDR strains and in dual therapy for gonorrhea. However, further research regarding the clinical treatment outcomes is essential.

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